Details for: E2F6
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 110.4823
Cell Significance Index: -17.1900 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 65.4462
Cell Significance Index: -16.6000 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 37.0947
Cell Significance Index: -15.0700 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 15.7844
Cell Significance Index: -15.0700 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 14.3882
Cell Significance Index: -17.7400 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 6.2564
Cell Significance Index: -16.7600 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 4.5134
Cell Significance Index: -17.8100 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 3.7442
Cell Significance Index: -11.5000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.9848
Cell Significance Index: 68.1100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.9149
Cell Significance Index: 90.5100 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.8942
Cell Significance Index: 12.2000 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.8545
Cell Significance Index: 23.2600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6838
Cell Significance Index: 617.3800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.6569
Cell Significance Index: 76.5500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.6452
Cell Significance Index: 128.0400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.5480
Cell Significance Index: 14.6900 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.5412
Cell Significance Index: 108.5700 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.5384
Cell Significance Index: 58.5700 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.5295
Cell Significance Index: 31.7900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.4968
Cell Significance Index: 80.8000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.3552
Cell Significance Index: 9.1300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.3440
Cell Significance Index: 9.9100 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.3363
Cell Significance Index: 9.6400 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.3111
Cell Significance Index: 19.6100 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.3084
Cell Significance Index: 13.9800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.2633
Cell Significance Index: 7.0300 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2280
Cell Significance Index: 81.7900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.2232
Cell Significance Index: 4.8400 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 0.2033
Cell Significance Index: 4.9600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1997
Cell Significance Index: 88.3100 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.1917
Cell Significance Index: 6.6600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1848
Cell Significance Index: 35.1700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.1792
Cell Significance Index: 22.0400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.1704
Cell Significance Index: 8.8500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1590
Cell Significance Index: 21.8300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.1590
Cell Significance Index: 12.2100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1550
Cell Significance Index: 27.9500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.1547
Cell Significance Index: 11.5300 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.1421
Cell Significance Index: 18.3600 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1401
Cell Significance Index: 96.9100 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.1385
Cell Significance Index: 75.6600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.1096
Cell Significance Index: 5.1500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.1023
Cell Significance Index: 5.7400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0643
Cell Significance Index: 3.0000 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0580
Cell Significance Index: 0.9700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.0542
Cell Significance Index: 1.5200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0502
Cell Significance Index: 3.5500 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0424
Cell Significance Index: 5.4400 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.0392
Cell Significance Index: 1.0300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0373
Cell Significance Index: 1.3100 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.0358
Cell Significance Index: 0.7500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.0247
Cell Significance Index: 1.6600 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: 0.0231
Cell Significance Index: 0.6800 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0122
Cell Significance Index: 0.2600 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 0.0046
Cell Significance Index: 0.0500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0001
Cell Significance Index: -0.2500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0004
Cell Significance Index: -0.2600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0069
Cell Significance Index: -12.7500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0080
Cell Significance Index: -12.2500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0099
Cell Significance Index: -4.5000 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0103
Cell Significance Index: -14.0500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0128
Cell Significance Index: -9.4000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0143
Cell Significance Index: -10.8100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0148
Cell Significance Index: -10.9900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0231
Cell Significance Index: -13.0400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0316
Cell Significance Index: -19.7200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0394
Cell Significance Index: -4.6500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0416
Cell Significance Index: -7.1000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0436
Cell Significance Index: -1.9300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0477
Cell Significance Index: -4.8700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0494
Cell Significance Index: -14.2200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0513
Cell Significance Index: -5.8800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0572
Cell Significance Index: -2.1700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0625
Cell Significance Index: -9.0900 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: -0.0784
Cell Significance Index: -1.1900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0863
Cell Significance Index: -18.1800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1114
Cell Significance Index: -7.1900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1154
Cell Significance Index: -7.0900 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.1258
Cell Significance Index: -0.7600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1272
Cell Significance Index: -7.8000 - Cell Name: type II muscle cell (CL0002212)
Fold Change: -0.1376
Cell Significance Index: -2.2200 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.1398
Cell Significance Index: -2.4700 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1503
Cell Significance Index: -3.8400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1505
Cell Significance Index: -7.9000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1636
Cell Significance Index: -17.0400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1778
Cell Significance Index: -9.2600 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.1828
Cell Significance Index: -4.5700 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1949
Cell Significance Index: -15.4400 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.2107
Cell Significance Index: -10.6500 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.2292
Cell Significance Index: -6.5400 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2383
Cell Significance Index: -4.6500 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.2551
Cell Significance Index: -2.0800 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: -0.2883
Cell Significance Index: -3.0100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.2901
Cell Significance Index: -9.2900 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.3010
Cell Significance Index: -6.5900 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.3058
Cell Significance Index: -8.1800 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.3468
Cell Significance Index: -2.3500 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.3506
Cell Significance Index: -11.4800 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.3532
Cell Significance Index: -11.2500 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.3599
Cell Significance Index: -4.2900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1157676999
Symbol: E2F6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9689056
Title: Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6.
PubMed ID: 9689056
PubMed ID: 9704927
Title: E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription.
PubMed ID: 9704927
PubMed ID: 15081404
Title: Human E2F6 is alternatively spliced to generate multiple protein isoforms.
PubMed ID: 15081404
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9501179
Title: E2F-6, a member of the E2F family that can behave as a transcriptional repressor.
PubMed ID: 9501179
PubMed ID: 12004135
Title: A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells.
PubMed ID: 12004135
PubMed ID: 15960975
Title: Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF.
PubMed ID: 15960975
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
Sequence Information:
- Length: 281
- Mass: 31844
- Checksum: 539E049C15AD3508
- Sequence:
MSQQRPARKL PSLLLDPTEE TVRRRCRDPI NVEGLLPSKI RINLEDNVQY VSMRKALKVK RPRFDVSLVY LTRKFMDLVR SAPGGILDLN KVATKLGVRK RRVYDITNVL DGIDLVEKKS KNHIRWIGSD LSNFGAVPQQ KKLQEELSDL SAMEDALDEL IKDCAQQLFE LTDDKENERL AYVTYQDIHS IQAFHEQIVI AVKAPAETRL DVPAPREDSI TVHIRSTNGP IDVYLCEVEQ GQTSNKRSEG VGTSSSESTH PEGPEEEENP QQSEELLEVS N
Genular Protein ID: 3981682292
Symbol: Q6Q9Z5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15081404
Title: Human E2F6 is alternatively spliced to generate multiple protein isoforms.
PubMed ID: 15081404
Sequence Information:
- Length: 129
- Mass: 14440
- Checksum: 97F8FC3A3E748510
- Sequence:
MEDALDELIK DCAQQLFELT DDKENERLAY VTYQDIHSIQ AFHEQIVIAV KAPAETRLDV PAPREDSITV HIRSTNGPID VYLCEVEQGQ TSNKRSEGVG TSSSESTHPE GPEEEENPQQ SEELLEVSN
Genular Protein ID: 813063836
Symbol: Q53YM3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
PubMed ID: 15081404
Title: Human E2F6 is alternatively spliced to generate multiple protein isoforms.
PubMed ID: 15081404
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 206
- Mass: 22982
- Checksum: 6C79669AFD6F42EC
- Sequence:
MDLVRSAPGG ILDLNKVATK LGVRKRRVYD ITNVLDGIDL VEKKSKNHIR WIGSDLSNFG AVPQQKKLQE ELSDLSAMED ALDELIKDCA QQLFELTDDK ENERLAYVTY QDIHSIQAFH EQIVIAVKAP AETRLDVPAP REDSITVHIR STNGPIDVYL CEVEQGQTSN KRSEGVGTSS SESTHPEGPE EEENPQQSEE LLEVSN
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.