Details for: ERCC3

Gene ID: 2071

Symbol: ERCC3

Ensembl ID: ENSG00000163161

Description: ERCC excision repair 3, TFIIH core complex helicase subunit

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: germ cell (CL0000586)
    Fold Change: 2.94
    Marker Score: 5132
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 1.62
    Marker Score: 2329
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.47
    Marker Score: 168265
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 1.46
    Marker Score: 422
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.19
    Marker Score: 10206
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.16
    Marker Score: 1786
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.15
    Marker Score: 10860
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.13
    Marker Score: 69704
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.13
    Marker Score: 11651
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.13
    Marker Score: 10717
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.04
    Marker Score: 38189
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 1.01
    Marker Score: 8807
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71713
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47938
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30394
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.98
    Marker Score: 897
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 0.97
    Marker Score: 1221
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2399
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.92
    Marker Score: 476
  • Cell Name: neuron (CL0000540)
    Fold Change: 0.92
    Marker Score: 3750
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.92
    Marker Score: 3560
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.91
    Marker Score: 432
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.9
    Marker Score: 2708
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 0.89
    Marker Score: 17617
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 0.88
    Marker Score: 33520
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5294
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 0.86
    Marker Score: 6575
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.85
    Marker Score: 4876
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.85
    Marker Score: 306
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 0.84
    Marker Score: 12615
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.81
    Marker Score: 2768
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 0.79
    Marker Score: 786
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.78
    Marker Score: 313
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1260
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 0.77
    Marker Score: 3206
  • Cell Name: interneuron (CL0000099)
    Fold Change: 0.77
    Marker Score: 351
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 0.77
    Marker Score: 309
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.76
    Marker Score: 577
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 0.75
    Marker Score: 414
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 0.75
    Marker Score: 356
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 0.75
    Marker Score: 261
  • Cell Name: plasmablast (CL0000980)
    Fold Change: 0.74
    Marker Score: 987
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.74
    Marker Score: 1559
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 0.72
    Marker Score: 2802
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.72
    Marker Score: 3031
  • Cell Name: multi-ciliated epithelial cell (CL0005012)
    Fold Change: 0.72
    Marker Score: 1371.5
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 0.72
    Marker Score: 2999
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.72
    Marker Score: 372
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 0.72
    Marker Score: 15272
  • Cell Name: large pre-B-II cell (CL0000957)
    Fold Change: 0.71
    Marker Score: 1922.5
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.69
    Marker Score: 764
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.69
    Marker Score: 335
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 0.68
    Marker Score: 452
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.68
    Marker Score: 173
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.67
    Marker Score: 610
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.66
    Marker Score: 1968
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.66
    Marker Score: 664
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 0.66
    Marker Score: 3050
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.65
    Marker Score: 475
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 0.65
    Marker Score: 273
  • Cell Name: blood cell (CL0000081)
    Fold Change: 0.65
    Marker Score: 7571.5
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.64
    Marker Score: 338
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.64
    Marker Score: 685
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.63
    Marker Score: 549
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.62
    Marker Score: 1367.5
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 0.62
    Marker Score: 1194
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 0.61
    Marker Score: 661
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 0.61
    Marker Score: 250
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 0.61
    Marker Score: 280
  • Cell Name: hematopoietic precursor cell (CL0008001)
    Fold Change: 0.61
    Marker Score: 214
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.61
    Marker Score: 404
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.61
    Marker Score: 6117
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.61
    Marker Score: 455
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 0.61
    Marker Score: 1651
  • Cell Name: oocyte (CL0000023)
    Fold Change: 0.6
    Marker Score: 148
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.6
    Marker Score: 9357
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.59
    Marker Score: 295
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.59
    Marker Score: 627
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 0.59
    Marker Score: 733
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 0.59
    Marker Score: 4359
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 0.58
    Marker Score: 957.5
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.58
    Marker Score: 658
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 0.57
    Marker Score: 206
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.57
    Marker Score: 209
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 0.56
    Marker Score: 647
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.56
    Marker Score: 2200
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.56
    Marker Score: 1169
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.56
    Marker Score: 226
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.56
    Marker Score: 3616
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: 0.56
    Marker Score: 558
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.55
    Marker Score: 141
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 0.55
    Marker Score: 192
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 0.55
    Marker Score: 344
  • Cell Name: erythroid progenitor cell, mammalian (CL0001066)
    Fold Change: 0.55
    Marker Score: 176
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.55
    Marker Score: 576
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.55
    Marker Score: 145
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.55
    Marker Score: 365
  • Cell Name: Unknown (CL0002371)
    Fold Change: 0.55
    Marker Score: 580
  • Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
    Fold Change: 0.54
    Marker Score: 1055
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.54
    Marker Score: 427

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Other Information

**Key characteristics:** * ERCC3 is a multi-functional protein that is involved in both DNA repair and genome-wide epigenetic regulation. * It is a key component of the TFIIH helicase complex, which is responsible for repairing DNA damage caused by a variety of agents, including ionizing radiation and chemicals. * ERCC3 is also involved in the regulation of gene expression through epigenetic mechanisms. **Pathways and functions:** * ERCC3 is involved in a variety of cellular processes, including DNA repair, genome-wide epigenetic regulation, and gene expression. * In DNA repair, ERCC3 is responsible for repairing double-strand DNA breaks caused by a variety of agents, including ionizing radiation and chemicals. * In genome-wide epigenetic regulation, ERCC3 helps to maintain the integrity of the genome by repairing DNA damage that could alter gene expression. * In gene expression, ERCC3 is involved in the regulation of a variety of genes, including those involved in DNA repair, cell cycle control, and apoptosis. **Clinical significance:** * Mutations in ERCC3 have been linked to a number of human diseases, including cancer and neurodegenerative disorders. * ERCC3 inhibitors are being investigated as potential cancer drugs. **Additional notes:** * ERCC3 is a highly conserved protein, with homologs found in a variety of other species. * ERCC3 is a relatively new protein, with the first human gene encoding this protein identified in 2003.

Genular Protein ID: 1993828114

Symbol: ERCC3_HUMAN

Name: General transcription and DNA repair factor IIH helicase subunit XPB

UniProtKB Accession Codes:

P19447 Q53QM0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CORUM 1 CTD 1 ChEBI 6 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EC 2 EMBL 5 EMDB 32 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 31 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 MoonProt 1 NCBI Taxonomy 1 NCBIfam 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PDB 40 PDBsum 35 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 29 RefSeq 1 Rhea 1 SAM 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2111438

Title: Molecular cloning and biological characterization of the human excision repair gene ERCC-3.

PubMed ID: 2111438

DOI: 10.1128/mcb.10.6.2570-2581.1990

PubMed ID: 2167179

Title: A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders Xeroderma pigmentosum and Cockayne's syndrome.

PubMed ID: 2167179

DOI: 10.1016/0092-8674(90)90122-u

PubMed ID: 1956789

Title: Structure and expression of the human XPBC/ERCC-3 gene involved in DNA repair disorders xeroderma pigmentosum and Cockayne's syndrome.

PubMed ID: 1956789

DOI: 10.1093/nar/19.22.6301

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8157004

Title: Correction of xeroderma pigmentosum repair defect by basal transcription factor BTF2 (TFIIH).

PubMed ID: 8157004

DOI: 10.1002/j.1460-2075.1994.tb06428.x

PubMed ID: 7724549

Title: The 62- and 80-kDa subunits of transcription factor IIH mediate the interaction with Epstein-Barr virus nuclear protein 2.

PubMed ID: 7724549

DOI: 10.1073/pnas.92.8.3259

PubMed ID: 9852112

Title: Immunoaffinity purification and functional characterization of human transcription factor IIH and RNA polymerase II from clonal cell lines that conditionally express epitope-tagged subunits of the multiprotein complexes.

PubMed ID: 9852112

DOI: 10.1074/jbc.273.51.34444

PubMed ID: 10024882

Title: Reconstitution of the transcription factor TFIIH: assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7.

PubMed ID: 10024882

DOI: 10.1016/s1097-2765(00)80177-x

PubMed ID: 10882074

Title: The FBP interacting repressor targets TFIIH to inhibit activated transcription.

PubMed ID: 10882074

DOI: 10.1016/s1097-2765(00)80428-1

PubMed ID: 11239393

Title: Defective interplay of activators and repressors with TFIH in xeroderma pigmentosum.

PubMed ID: 11239393

DOI: 10.1016/s0092-8674(01)00223-9

PubMed ID: 10447254

Title: A summary of mutations in the UV-sensitive disorders: xeroderma pigmentosum, Cockayne syndrome, and trichothiodystrophy.

PubMed ID: 10447254

DOI: 10.1002/(sici)1098-1004(1999)14:1<9::aid-humu2>3.0.co;2-6

PubMed ID: 19106100

Title: MCAF1/AM is involved in Sp1-mediated maintenance of cancer-associated telomerase activity.

PubMed ID: 19106100

DOI: 10.1074/jbc.m807098200

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 30894545

Title: Functional interplay between TFIIH and KAT2A regulates higher-order chromatin structure and class II gene expression.

PubMed ID: 30894545

DOI: 10.1038/s41467-019-09270-2

PubMed ID: 23385459

Title: Structure of the C-terminal half of human XPB helicase and the impact of the disease-causing mutation XP11BE.

PubMed ID: 23385459

DOI: 10.1107/s0907444912045040

PubMed ID: 8304337

Title: Clinical heterogeneity within xeroderma pigmentosum associated with mutations in the DNA repair and transcription gene ERCC3.

PubMed ID: 8304337

PubMed ID: 9012405

Title: A mutation in the XPB/ERCC3 DNA repair transcription gene, associated with trichothiodystrophy.

PubMed ID: 9012405

PubMed ID: 10862089

Title: Identification of four single nucleotide polymorphisms in DNA repair genes: XPA and XPB (ERCC3) in Polish population.

PubMed ID: 10862089

DOI: 10.1002/1098-1004(200006)15:6<577::aid-humu11>3.0.co;2-w

PubMed ID: 16947863

Title: Phenotypic heterogeneity in the XPB DNA helicase gene (ERCC3): xeroderma pigmentosum without and with Cockayne syndrome.

PubMed ID: 16947863

DOI: 10.1002/humu.20392

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 782
  • Mass: 89278
  • Checksum: F5F4D3A89A7DF826
  • Sequence:
    • MGKRDRADRD KKKSRKRHYE DEEDDEEDAP GNDPQEAVPS AAGKQVDESG TKVDEYGAKD 
YRLQMPLKDD HTSRPLWVAP DGHIFLEAFS PVYKYAQDFL VAIAEPVCRP THVHEYKLTA 
YSLYAAVSVG LQTSDITEYL RKLSKTGVPD GIMQFIKLCT VSYGKVKLVL KHNRYFVESC 
HPDVIQHLLQ DPVIRECRLR NSEGEATELI TETFTSKSAI SKTAESSGGP STSRVTDPQG 
KSDIPMDLFD FYEQMDKDEE EEEETQTVSF EVKQEMIEEL QKRCIHLEYP LLAEYDFRND 
SVNPDINIDL KPTAVLRPYQ EKSLRKMFGN GRARSGVIVL PCGAGKSLVG VTAACTVRKR 
CLVLGNSAVS VEQWKAQFKM WSTIDDSQIC RFTSDAKDKP IGCSVAISTY SMLGHTTKRS 
WEAERVMEWL KTQEWGLMIL DEVHTIPAKM FRRVLTIVQA HCKLGLTATL VREDDKIVDL 
NFLIGPKLYE ANWMELQNNG YIAKVQCAEV WCPMSPEFYR EYVAIKTKKR ILLYTMNPNK 
FRACQFLIKF HERRNDKIIV FADNVFALKE YAIRLNKPYI YGPTSQGERM QILQNFKHNP 
KINTIFISKV GDTSFDLPEA NVLIQISSHG GSRRQEAQRL GRVLRAKKGM VAEEYNAFFY 
SLVSQDTQEM AYSTKRQRFL VDQGYSFKVI TKLAGMEEED LAFSTKEEQQ QLLQKVLAAT 
DLDAEEEVVA GEFGSRSSQA SRRFGTMSSM SGADDTVYME YHSSRSKAPS KHVHPLFKRF 
RK

Genular Protein ID: 325580115

Symbol: B3KRG2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KRG2

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 5 DNASU 1 EC 1 EMBL 2 GO 6 Gene3D 1 GenomeRNAi 1 InterPro 7 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PeptideAtlas 1 Pfam 3 RefSeq 1 Rhea 1 SAM 1 SMART 2 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 718
  • Mass: 82012
  • Checksum: 37BB0F843DAB4BD9
  • Sequence:
    • MPLKDDHTSR PLWVAPDGHI FLEAFSPVYK YAQDFLVAIA EPVCRPTHVH EYKLTAYSLY 
AAVSVGLQTS DITEYLRKLS KTGVPDGIMQ FIKLCTVSYG KVKLVLKHNR YFVESCHPDV 
IQHLLQDPVI RECRLRNSEG EATELITETF TSKSAISKTA ESSGGPSTSR VTDPQGKSDI 
PMDLFDFYEQ MDKDEEEEEE TQTVSFEVKQ EMIEELQKRC IHLEYPLLAE YDFRNDSVNP 
DINIDLKPTA VLRPYQEKSL RKMFGNGRAR SGVIVLPCGA GKSLVGVTAV CTVRKRCLVL 
GNSAVSVEQW KAQFKMWSTI DDSQICRFTS DAKDKPIGCS VAISTYSMLG HTTKRSWEAE 
RVMEWLKTQE WGLMILDEVH TIPAKMFRRV LTIVQAHCKL GLTATLVRED DKIVDLNFLI 
GPKLYEANWM ELQNNGYIAK VQCAEVWCPM SPEFYREYVA IKTKKRILLY TMNPNKFRAC 
QFLIKFHERR NDKIIVFADN VFALKEYAIR LNKPYIYGPT SQGERMQILQ NFKHNPKINT 
IFISKVGDTS FDLPEANVLI QISSHGGSRR QEAQRLGRVL RAKKGMVAEE YNAFFYSLVS 
QDTQEMAYST KRQRFLVDQG YSFKVITKLA GMEEEDLAFS TKEEQQQLLQ KVLAATDLDA 
EEEVVAGEFG SRSSQASRRF GTMSSMSGAD DTVYMEYHSS RSKAPSKHVH PLFKRFRK

Genular Protein ID: 1633057564

Symbol: B3KTH1_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KTH1

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 5 DNASU 1 EC 1 EMBL 2 GO 6 Gene3D 1 GenomeRNAi 1 InterPro 7 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PeptideAtlas 1 Pfam 3 RefSeq 2 Rhea 1 SAM 1 SMART 2 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 718
  • Mass: 81886
  • Checksum: 33369E27C1EB5D16
  • Sequence:
    • MPLKDDHTSR PLWVAPDGHI FLEAFSPVYK YAQDFLVAIA EPVCRPTHVH EYKLTAHSLY 
AAVSVGLQTS DITEYLRKLS KTGVPDGIMQ FIKLCTVSYG KVKLVLKHNR YFVESCHPDV 
IQHLLQDPVI RECRLRNSEG EATELITETF TSKSAISKTA ESSGGPSTSR VTDPQGKSDI 
PMDLFDFYEQ MDKDEEEEEE TQTVSFEVKQ EMIGELQKRC IHLEYPLLAE YDFRNDSVNP 
DINIDLKPTA VLRPYQEKSL RKMFGNGRAR SGVIVLPCGA GKSLVGVTAA CTVRKRCLVL 
GNSAVSVEQW KAQFKMWSTI DDSQICRFTS DAKDKPIGCS VAISTYSMLG HTTKRSWEAE 
RVMEWLKTQE WGLMILDEVH TIPAKMFRRV LTIVQAHCKL GLTATLVRED DKIVDLNFLI 
GPKLYEANWM ELQNNGYIAK VQCAEVWCPM SPEFYREYVA IKTKKRILLY TMNPNKFRAC 
QFLIKFHERR NDKIIVFADN VFALKEYAIR LNKPYIYGPT SQGERMQILQ NFKHNPKINT 
IFISKVGDTS FDLPEANVLI QISSHGGSRR QEAQRLGRVL RAKKGMVAEE YNAFFYSLVS 
QDTQEMAYST KRQRFLVDQG YSFKVITKLA GMEEEDLAFS TKEEQQQLLQ KVLAATDLDA 
EEEVVAGEFG SRSSQASRRF GTMSSMSGAD DTVYMEYHSS RSKAPSKHVH PLFKRFRK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.