Details for: EXT2

Gene ID: 2132

Symbol: EXT2

Ensembl ID: ENSG00000151348

Description: exostosin glycosyltransferase 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 243.7233
    Cell Significance Index: -37.9100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 144.2577
    Cell Significance Index: -36.5900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 81.9067
    Cell Significance Index: -38.6700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 78.8417
    Cell Significance Index: -32.0300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 33.6216
    Cell Significance Index: -32.1000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 31.1690
    Cell Significance Index: -38.4300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 13.6588
    Cell Significance Index: -36.5900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 10.4478
    Cell Significance Index: -32.0900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 9.7667
    Cell Significance Index: -38.5400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 8.3707
    Cell Significance Index: -18.3200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.9448
    Cell Significance Index: 390.1300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.6564
    Cell Significance Index: 114.5500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.3587
    Cell Significance Index: 487.3600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.1129
    Cell Significance Index: 1004.8900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.8278
    Cell Significance Index: 46.4500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.8262
    Cell Significance Index: 18.0900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.7988
    Cell Significance Index: 30.2500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7873
    Cell Significance Index: 156.2500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7498
    Cell Significance Index: 81.5600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.7475
    Cell Significance Index: 33.0700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.7421
    Cell Significance Index: 44.5500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.6717
    Cell Significance Index: 51.5500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6708
    Cell Significance Index: 109.1100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.6143
    Cell Significance Index: 424.8400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.5680
    Cell Significance Index: 38.1900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.4933
    Cell Significance Index: 30.3200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4363
    Cell Significance Index: 43.1600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.4084
    Cell Significance Index: 7.9700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3629
    Cell Significance Index: 44.6200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3586
    Cell Significance Index: 7.7700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3462
    Cell Significance Index: 47.5400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2991
    Cell Significance Index: 53.9200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2817
    Cell Significance Index: 8.1200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2660
    Cell Significance Index: 145.2700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.2604
    Cell Significance Index: 7.4300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2426
    Cell Significance Index: 6.7800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2402
    Cell Significance Index: 30.7900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2121
    Cell Significance Index: 9.8900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.1906
    Cell Significance Index: 9.9300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1708
    Cell Significance Index: 7.7400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1532
    Cell Significance Index: 29.1500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.1408
    Cell Significance Index: 3.6200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.1226
    Cell Significance Index: 2.9400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0866
    Cell Significance Index: 38.2800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0852
    Cell Significance Index: 160.4200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0821
    Cell Significance Index: 126.4600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0654
    Cell Significance Index: 1.1200
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.0572
    Cell Significance Index: 0.7100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0551
    Cell Significance Index: 25.0000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0535
    Cell Significance Index: 98.6100
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.0521
    Cell Significance Index: 0.7500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0476
    Cell Significance Index: 30.2300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0414
    Cell Significance Index: 1.9500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0221
    Cell Significance Index: 30.0500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0218
    Cell Significance Index: 1.1300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0162
    Cell Significance Index: 0.5700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0123
    Cell Significance Index: 2.1000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0176
    Cell Significance Index: -0.4700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0237
    Cell Significance Index: -3.4400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0361
    Cell Significance Index: -26.4700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0385
    Cell Significance Index: -29.1200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0404
    Cell Significance Index: -29.9200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0657
    Cell Significance Index: -37.0700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0670
    Cell Significance Index: -8.6600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0683
    Cell Significance Index: -42.6400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0899
    Cell Significance Index: -1.5100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1052
    Cell Significance Index: -10.7500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1155
    Cell Significance Index: -13.4700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1157
    Cell Significance Index: -33.2800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1768
    Cell Significance Index: -4.4200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1960
    Cell Significance Index: -22.4600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1995
    Cell Significance Index: -42.0300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2180
    Cell Significance Index: -16.2500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2471
    Cell Significance Index: -29.1400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2537
    Cell Significance Index: -17.9400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2691
    Cell Significance Index: -5.7300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2735
    Cell Significance Index: -7.4500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2743
    Cell Significance Index: -17.2900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2835
    Cell Significance Index: -29.5200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3155
    Cell Significance Index: -6.5500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3381
    Cell Significance Index: -4.6100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3429
    Cell Significance Index: -22.1300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3675
    Cell Significance Index: -12.7700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.3927
    Cell Significance Index: -8.2200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3975
    Cell Significance Index: -12.7300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.4042
    Cell Significance Index: -8.6400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4383
    Cell Significance Index: -34.7100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.4543
    Cell Significance Index: -11.6100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4714
    Cell Significance Index: -24.7500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.5032
    Cell Significance Index: -10.6800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.5093
    Cell Significance Index: -16.2200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.5153
    Cell Significance Index: -16.8700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.5156
    Cell Significance Index: -14.7800
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.5365
    Cell Significance Index: -6.6900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.5487
    Cell Significance Index: -11.0200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.5503
    Cell Significance Index: -14.7500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5636
    Cell Significance Index: -14.8200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.6069
    Cell Significance Index: -12.0000
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.6259
    Cell Significance Index: -9.2400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6265
    Cell Significance Index: -38.4100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** EXT2 is a glycosyltransferase enzyme that catalyzes the addition of glucuronic acid and N-acetylglucosamine to the core protein of HSPGs. The enzyme is composed of two subunits, EXT1 and EXT2, which work together to generate a wide range of HSPGs with varying degrees of sulfation and glycosylation. EXT2 is specifically involved in the synthesis of dermatan sulfate (DS) and heparan sulfate (HS), two important types of HSPGs. **Pathways and Functions** EXT2 is involved in several cellular pathways, including: 1. **Cell Signaling**: HSPGs play a crucial role in cell signaling, and EXT2 is involved in the regulation of various signaling pathways, including the fibroblast growth factor (FGF) pathway. 2. **Growth and Differentiation**: HSPGs are involved in the regulation of cell growth and differentiation, and EXT2 is required for the proper formation of chondrocytes and endochondral bone morphogenesis. 3. **Blood Pressure Regulation**: EXT2 is involved in the regulation of blood pressure, and mutations in the EXT2 gene have been associated with hypertension. 4. **Vasodilation**: HSPGs are involved in the regulation of vasodilation, and EXT2 is required for the proper functioning of endothelial cells. **Clinical Significance** Mutations in the EXT2 gene have been associated with Exostoses 2, a rare genetic disorder characterized by the formation of multiple bony tumors. Exostoses 2 is caused by mutations in the EXT1 gene, which leads to the accumulation of abnormal HSPGs and the formation of osteochondromas. EXT2 mutations have also been associated with other diseases, including: 1. **Exostoses 1**: Mutations in the EXT1 gene have been associated with Exostoses 1, a rare genetic disorder characterized by the formation of multiple bony tumors. 2. **Trps2**: Mutations in the EXT2 gene have been associated with Trps2, a rare genetic disorder characterized by the formation of multiple bony tumors. 3. **Chds**: Mutations in the EXT2 gene have been associated with Chds, a rare genetic disorder characterized by the formation of multiple bony tumors. 4. **Hypertension**: EXT2 mutations have been associated with hypertension, and HSPGs play a crucial role in the regulation of blood pressure. In summary, EXT2 is a crucial gene involved in the biosynthesis of HSPGs, and mutations in the EXT2 gene have been associated with several diseases, including Exostoses 2, Trps2, Chds, and hypertension. Further research is needed to fully understand the role of EXT2 in human disease and to develop effective therapeutic strategies for the treatment of EXT2-related disorders.

Genular Protein ID: 1112176334

Symbol: EXT2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q93063 B2R5Z6 C9JU51 J3KPT2 O15288

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 2 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CAZy 2 CCDS 2 CORUM 1 CTD 1 ChEBI 31 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 24 Ensembl 6 GO 33 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 6 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 6 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 3 RefSeq 3 Rhea 4 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8782816

Title: The EXT2 multiple exostoses gene defines a family of putative tumour suppressor genes.

PubMed ID: 8782816

DOI: 10.1038/ng0996-25

PubMed ID: 8894688

Title: Positional cloning of a gene involved in hereditary multiple exostoses.

PubMed ID: 8894688

DOI: 10.1093/hmg/5.10.1547

PubMed ID: 9110175

Title: The structure of the human multiple exostoses 2 gene and characterization of homologs in mouse and Caenorhabditis elegans.

PubMed ID: 9110175

DOI: 10.1101/gr.7.4.359

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10679296

Title: Association of EXT1 and EXT2, hereditary multiple exostoses gene products, in Golgi apparatus.

PubMed ID: 10679296

DOI: 10.1006/bbrc.2000.2219

PubMed ID: 10545594

Title: A direct interaction between EXT proteins and glycosyltransferases is defective in hereditary multiple exostoses.

PubMed ID: 10545594

DOI: 10.1093/hmg/8.12.2155

PubMed ID: 18337501

Title: Heparan sulfate biosynthesis enzymes EXT1 and EXT2 affect NDST1 expression and heparan sulfate sulfation.

PubMed ID: 18337501

DOI: 10.1073/pnas.0705807105

PubMed ID: 22660413

Title: Syndecan-syntenin-ALIX regulates the biogenesis of exosomes.

PubMed ID: 22660413

DOI: 10.1038/ncb2502

PubMed ID: 35137078

Title: A dominant negative splice variant of the heparan sulfate biosynthesis enzyme NDST1 reduces heparan sulfate sulfation.

PubMed ID: 35137078

DOI: 10.1093/glycob/cwac004

PubMed ID: 36402845

Title: Structure of the human heparan sulfate polymerase complex EXT1-EXT2.

PubMed ID: 36402845

DOI: 10.1038/s41467-022-34882-6

PubMed ID: 36593275

Title: Structural basis for heparan sulfate co-polymerase action by the EXT1-2 complex.

PubMed ID: 36593275

DOI: 10.1038/s41589-022-01220-2

PubMed ID: 26246518

Title: Old gene, new phenotype: mutations in heparan sulfate synthesis enzyme, EXT2 leads to seizure and developmental disorder, no exostoses.

PubMed ID: 26246518

DOI: 10.1136/jmedgenet-2015-103279

PubMed ID: 9326317

Title: Mutation screening of the EXT1 and EXT2 genes in patients with hereditary multiple exostoses.

PubMed ID: 9326317

DOI: 10.1086/515505

PubMed ID: 10480354

Title: Mutation analysis of hereditary multiple exostoses in the Chinese.

PubMed ID: 10480354

DOI: 10.1007/s004399900058

PubMed ID: 10429361

Title: Germline mutations in the EXT1 and EXT2 genes in Korean patients with hereditary multiple exostoses.

PubMed ID: 10429361

DOI: 10.1007/s100380050149

PubMed ID: 10738008

Title: An R223P mutation in EXT2 gene causes hereditary multiple exostoses.

PubMed ID: 10738008

DOI: 10.1002/(sici)1098-1004(200004)15:4<390::aid-humu35>3.0.co;2-e

PubMed ID: 11170095

Title: Mutation frequencies of EXT1 and EXT2 in 43 Japanese families with hereditary multiple exostoses.

PubMed ID: 11170095

DOI: 10.1002/1096-8628(20010215)99:1<59::aid-ajmg1115>3.0.co;2-z

PubMed ID: 11169766

Title: Diminished levels of the putative tumor suppressor proteins EXT1 and EXT2 in exostosis chondrocytes.

PubMed ID: 11169766

DOI: 10.1002/1097-0169(200102)48:2<149::aid-cm1005>3.0.co;2-3

PubMed ID: 11668521

Title: Ext-mutation analysis in Italian sporadic and hereditary osteochondromas.

PubMed ID: 11668521

DOI: 10.1002/1097-0215(20011120)95:6<378::aid-ijc1067>3.0.co;2-f

PubMed ID: 11432960

Title: Genotype-phenotype correlation in hereditary multiple exostoses.

PubMed ID: 11432960

DOI: 10.1136/jmg.38.7.430

PubMed ID: 19344451

Title: New mutations of EXT1 and EXT2 genes in German patients with Multiple Osteochondromas.

PubMed ID: 19344451

DOI: 10.1111/j.1469-1809.2009.00508.x

Sequence Information:

  • Length: 718
  • Mass: 82255
  • Checksum: 9048CD3A5B63C5CB
  • Sequence:
    • MCASVKYNIR GPALIPRMKT KHRIYYITLF SIVLLGLIAT GMFQFWPHSI ESSNDWNVEK 
RSIRDVPVVR LPADSPIPER GDLSCRMHTC FDVYRCGFNP KNKIKVYIYA LKKYVDDFGV 
SVSNTISREY NELLMAISDS DYYTDDINRA CLFVPSIDVL NQNTLRIKET AQAMAQLSRW 
DRGTNHLLFN MLPGGPPDYN TALDVPRDRA LLAGGGFSTW TYRQGYDVSI PVYSPLSAEV 
DLPEKGPGPR QYFLLSSQVG LHPEYREDLE ALQVKHGESV LVLDKCTNLS EGVLSVRKRC 
HKHQVFDYPQ VLQEATFCVV LRGARLGQAV LSDVLQAGCV PVVIADSYIL PFSEVLDWKR 
ASVVVPEEKM SDVYSILQSI PQRQIEEMQR QARWFWEAYF QSIKAIALAT LQIINDRIYP 
YAAISYEEWN DPPAVKWGSV SNPLFLPLIP PQSQGFTAIV LTYDRVESLF RVITEVSKVP 
SLSKLLVVWN NQNKNPPEDS LWPKIRVPLK VVRTAENKLS NRFFPYDEIE TEAVLAIDDD 
IIMLTSDELQ FGYEVWREFP DRLVGYPGRL HLWDHEMNKW KYESEWTNEV SMVLTGAAFY 
HKYFNYLYTY KMPGDIKNWV DAHMNCEDIA MNFLVANVTG KAVIKVTPRK KFKCPECTAI 
DGLSLDQTHM VERSECINKF ASVFGTMPLK VVEHRADPVL YKDDFPEKLK SFPNIGSL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.