Details for: ACSL1

Gene ID: 2180

Symbol: ACSL1

Ensembl ID: ENSG00000151726

Description: acyl-CoA synthetase long chain family member 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 254.4276
    Cell Significance Index: -39.5800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 162.5511
    Cell Significance Index: -41.2300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 87.3585
    Cell Significance Index: -35.4900
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 76.9462
    Cell Significance Index: -39.5800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 37.2247
    Cell Significance Index: -35.5400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 33.3649
    Cell Significance Index: -41.1400
  • Cell Name: sebaceous gland cell (CL2000021)
    Fold Change: 25.0732
    Cell Significance Index: 32.4400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 14.2897
    Cell Significance Index: -38.2800
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 13.8593
    Cell Significance Index: 233.4600
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 10.8966
    Cell Significance Index: 47.4400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.6524
    Cell Significance Index: -42.0400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 10.2134
    Cell Significance Index: -31.3700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.0195
    Cell Significance Index: -19.7400
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 5.1932
    Cell Significance Index: 126.7100
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 5.0650
    Cell Significance Index: 63.7800
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: 2.8819
    Cell Significance Index: 46.5000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.9232
    Cell Significance Index: 17.7100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.6856
    Cell Significance Index: 31.1600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.6049
    Cell Significance Index: 123.1600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.5738
    Cell Significance Index: 183.4100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.2350
    Cell Significance Index: 235.0200
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 1.0734
    Cell Significance Index: 2.4200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.0437
    Cell Significance Index: 207.1200
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.0034
    Cell Significance Index: 14.8100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.9469
    Cell Significance Index: 24.3400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.6430
    Cell Significance Index: 30.2200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6195
    Cell Significance Index: 124.2700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6140
    Cell Significance Index: 554.4000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.5695
    Cell Significance Index: 26.5600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4985
    Cell Significance Index: 89.8600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4187
    Cell Significance Index: 150.1900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3616
    Cell Significance Index: 58.8100
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 0.2674
    Cell Significance Index: 1.5400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.2375
    Cell Significance Index: 16.8000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.2278
    Cell Significance Index: 24.7800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2053
    Cell Significance Index: 25.2500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2020
    Cell Significance Index: 89.3300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1680
    Cell Significance Index: 116.2100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1321
    Cell Significance Index: 72.1200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1069
    Cell Significance Index: 201.2600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0799
    Cell Significance Index: 58.5500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0692
    Cell Significance Index: 43.9700
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.0646
    Cell Significance Index: 1.0000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0597
    Cell Significance Index: 5.9100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0581
    Cell Significance Index: 26.3900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0490
    Cell Significance Index: 6.3300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0474
    Cell Significance Index: 35.9000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0274
    Cell Significance Index: 42.2000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.0163
    Cell Significance Index: 1.6600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.0067
    Cell Significance Index: 0.4000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0059
    Cell Significance Index: 0.1700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0017
    Cell Significance Index: 3.1200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0018
    Cell Significance Index: -0.3100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0045
    Cell Significance Index: -3.3000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0154
    Cell Significance Index: -1.0700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0166
    Cell Significance Index: -9.3600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0166
    Cell Significance Index: -22.6200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0178
    Cell Significance Index: -2.4500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0239
    Cell Significance Index: -14.9300
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0466
    Cell Significance Index: -0.3800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0831
    Cell Significance Index: -1.8000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0869
    Cell Significance Index: -18.3100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0968
    Cell Significance Index: -11.4200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1165
    Cell Significance Index: -16.9400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1166
    Cell Significance Index: -33.5400
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1240
    Cell Significance Index: -1.8300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.1609
    Cell Significance Index: -3.1400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1621
    Cell Significance Index: -8.4200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1727
    Cell Significance Index: -22.1400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1728
    Cell Significance Index: -10.6000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1905
    Cell Significance Index: -21.7500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1990
    Cell Significance Index: -5.5600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2013
    Cell Significance Index: -8.9000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.2111
    Cell Significance Index: -9.5700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2165
    Cell Significance Index: -14.5600
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.2228
    Cell Significance Index: -3.2000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2294
    Cell Significance Index: -23.8900
  • Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
    Fold Change: -0.2458
    Cell Significance Index: -2.4600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2511
    Cell Significance Index: -9.5100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2535
    Cell Significance Index: -20.0800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2540
    Cell Significance Index: -16.3900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3090
    Cell Significance Index: -35.4000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3594
    Cell Significance Index: -7.4600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3596
    Cell Significance Index: -22.1000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3891
    Cell Significance Index: -29.0000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.4491
    Cell Significance Index: -28.3100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.4593
    Cell Significance Index: -16.1400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.5216
    Cell Significance Index: -27.1700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.5441
    Cell Significance Index: -14.5600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.5606
    Cell Significance Index: -14.9700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.5777
    Cell Significance Index: -9.9000
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.5802
    Cell Significance Index: -25.2300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.5803
    Cell Significance Index: -16.5600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.5942
    Cell Significance Index: -33.3500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.6229
    Cell Significance Index: -13.6400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.6489
    Cell Significance Index: -16.2200
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.6885
    Cell Significance Index: -8.6900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.6891
    Cell Significance Index: -36.1800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.7003
    Cell Significance Index: -14.9200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.7108
    Cell Significance Index: -22.7700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** ACSL1 is a long-chain acyl-CoA synthetase, which means it is responsible for the synthesis of long-chain acyl-CoA molecules from fatty acids. The enzyme is composed of multiple subunits, which are involved in the catalytic activity of the enzyme. ACSL1 is highly expressed in various tissues, including adipose tissue, skeletal muscle, and liver, where it plays a significant role in regulating lipid metabolism. Notably, ACSL1 is activated by PPARα (peroxisome proliferator-activated receptor alpha), a transcription factor that regulates the expression of genes involved in lipid metabolism. **Pathways and Functions** ACSL1 is involved in several key pathways and functions, including: 1. **Fatty acid biosynthesis**: ACSL1 is responsible for the synthesis of long-chain acyl-CoA molecules from fatty acids, which are then used to produce energy, synthesize lipids, and regulate cell signaling. 2. **Fatty acid metabolism**: ACSL1 plays a crucial role in regulating fatty acid metabolism, particularly in the context of obesity and metabolic disorders. 3. **Lipid biosynthesis**: ACSL1 is involved in the synthesis of triglycerides, which are an essential component of lipids. 4. **Cell signaling**: ACSL1 is activated by PPARα, which regulates the expression of genes involved in lipid metabolism and cell signaling. 5. **Energy production**: ACSL1 is involved in the production of energy from fatty acids, which is essential for maintaining energy homeostasis. **Clinical Significance** ACSL1 has been implicated in various metabolic disorders, including: 1. **Obesity**: ACSL1 has been shown to play a role in regulating fat storage and energy expenditure, making it a potential target for obesity treatment. 2. **Insulin resistance**: ACSL1 has been implicated in the development of insulin resistance, a key feature of type 2 diabetes. 3. **Metabolic syndrome**: ACSL1 has been shown to play a role in the development of metabolic syndrome, a cluster of metabolic disorders that increase the risk of cardiovascular disease. 4. **Cancer**: ACSL1 has been implicated in the development and progression of certain types of cancer, including breast and prostate cancer. In conclusion, ACSL1 is a critical enzyme involved in the regulation of fatty acid metabolism and lipid biosynthesis. Its dysregulation has been implicated in various metabolic disorders, making it a potential target for the treatment of obesity, insulin resistance, and metabolic syndrome.

Genular Protein ID: 376631604

Symbol: ACSL1_HUMAN

Name: Acyl-CoA synthetase 1

UniProtKB Accession Codes:

P33121 B7Z452 D3DP57 P41215 Q8N8V7 Q8TA99

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CPTAC 2 CTD 1 ChEBI 67 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 EC 3 EMBL 11 Ensembl 9 ExpressionAtlas 1 GO 27 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 4 RefSeq 12 Rhea 22 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissLipids 2 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1607358

Title: Human long-chain acyl-CoA synthetase: structure and chromosomal location.

PubMed ID: 1607358

DOI: 10.1093/oxfordjournals.jbchem.a123707

PubMed ID: 8584017

Title: Molecular cloning and sequencing of human palmitoyl-CoA ligase and its tissue specific expression.

PubMed ID: 8584017

DOI: 10.1007/bf01076899

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10548543

Title: Identification and molecular characterization of acyl-CoA synthetase in human red cells and erythroid precursor.

PubMed ID: 10548543

DOI: 10.1042/bj3440135

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21242590

Title: Long-chain acyl-CoA synthetase 4 modulates prostaglandin E(2) release from human arterial smooth muscle cells.

PubMed ID: 21242590

DOI: 10.1194/jlr.m013292

PubMed ID: 22633490

Title: The Sjogren-Larsson syndrome gene encodes a hexadecenal dehydrogenase of the sphingosine 1-phosphate degradation pathway.

PubMed ID: 22633490

DOI: 10.1016/j.molcel.2012.04.033

PubMed ID: 24269233

Title: Identification of acyl-CoA synthetases involved in the mammalian sphingosine 1-phosphate metabolic pathway.

PubMed ID: 24269233

DOI: 10.1016/j.bbrc.2013.11.036

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

Sequence Information:

  • Length: 698
  • Mass: 77943
  • Checksum: FD6669453589D362
  • Sequence:
    • MQAHELFRYF RMPELVDFRQ YVRTLPTNTL MGFGAFAALT TFWYATRPKP LKPPCDLSMQ 
SVEVAGSGGA RRSALLDSDE PLVYFYDDVT TLYEGFQRGI QVSNNGPCLG SRKPDQPYEW 
LSYKQVAELS ECIGSALIQK GFKTAPDQFI GIFAQNRPEW VIIEQGCFAY SMVIVPLYDT 
LGNEAITYIV NKAELSLVFV DKPEKAKLLL EGVENKLIPG LKIIVVMDAY GSELVERGQR 
CGVEVTSMKA MEDLGRANRR KPKPPAPEDL AVICFTSGTT GNPKGAMVTH RNIVSDCSAF 
VKATENTVNP CPDDTLISFL PLAHMFERVV ECVMLCHGAK IGFFQGDIRL LMDDLKVLQP 
TVFPVVPRLL NRMFDRIFGQ ANTTLKRWLL DFASKRKEAE LRSGIIRNNS LWDRLIFHKV 
QSSLGGRVRL MVTGAAPVSA TVLTFLRAAL GCQFYEGYGQ TECTAGCCLT MPGDWTAGHV 
GAPMPCNLIK LVDVEEMNYM AAEGEGEVCV KGPNVFQGYL KDPAKTAEAL DKDGWLHTGD 
IGKWLPNGTL KIIDRKKHIF KLAQGEYIAP EKIENIYMRS EPVAQVFVHG ESLQAFLIAI 
VVPDVETLCS WAQKRGFEGS FEELCRNKDV KKAILEDMVR LGKDSGLKPF EQVKGITLHP 
ELFSIDNGLL TPTMKAKRPE LRNYFRSQID DLYSTIKV

Genular Protein ID: 1262466549

Symbol: B4E0R0_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4E0R0

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 42 DNASU 1 DisGeNET 1 EC 2 EMBL 2 GO 4 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 Pfam 2 RefSeq 1 Rhea 14 RuleBase 1 SUPFAM 1

Sequence Information:

  • Length: 664
  • Mass: 74254
  • Checksum: D10CABE7BECDBD4A
  • Sequence:
    • MQAHELFRYF RMPELVDFRQ YVRTLPTNTL MGFGAFAALT TFWYATRPKP LKPPCDLSMQ 
SVEVAGSGGA RRSALLDSDE PLVYFYDDVT TLYEGFQRGI QVSNNGPCLG SRKPDQPYEW 
LSYKQWVIIE QGCFAYSMVI VPLYDTLGNE AITYIVNKAE LSLVFVDKPE KAKLLLEGVE 
NKLIPGLKII VVMDAYGSEL VERGQRCGVE VTSMKAMEDL GRANRRKPKP PAPEDLAVIC 
FTSGTTGNPK GAMVTHRNIV SDCSAFVKAT ENTVNPCPDD TLISFLPLAH MFERVVECVM 
LCHGAKIGFF QGDIRLLMDD LKVLQPTVFP VVPRLLNRMF DRIFGQANTT LKRWLLDFAS 
KRKEAELRSG IIRNNSLWDR LIFHKVQSSL GGRVRLMVTG AAPVSATVLT FLRAALGCQF 
YEGYGQTECT AGCCLTMPGD WTAGHVGAPM PCNLIKLVDV EEMNYMAAEG EGEVCVKGPN 
VFQGYLKDPA KTAEALDKDG WLHTGDIGKW LPNGTLKIID RKKHIFKLAQ GEYIAPEKIE 
NIYMRSEPVA QVFVHGESLQ AFLIAIVVPD VETLCSWAQK RGFEGSFEEL CRNKDVKKAI 
LEDMVRLGKD SGLKPFEQVK GITLHPELFS IDNGLLTPTM KAKKPELRNY FRSQIDDLYS 
TIKV

Genular Protein ID: 3136503317

Symbol: E7EPM6_HUMAN

Name: N/A

UniProtKB Accession Codes:

E7EPM6 E7EQJ5

Database IDs:

ARBA 12 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 42 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 2 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 Rhea 14 RuleBase 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 664
  • Mass: 74282
  • Checksum: D10CABE7AC7A4D4A
  • Sequence:
    • MQAHELFRYF RMPELVDFRQ YVRTLPTNTL MGFGAFAALT TFWYATRPKP LKPPCDLSMQ 
SVEVAGSGGA RRSALLDSDE PLVYFYDDVT TLYEGFQRGI QVSNNGPCLG SRKPDQPYEW 
LSYKQWVIIE QGCFAYSMVI VPLYDTLGNE AITYIVNKAE LSLVFVDKPE KAKLLLEGVE 
NKLIPGLKII VVMDAYGSEL VERGQRCGVE VTSMKAMEDL GRANRRKPKP PAPEDLAVIC 
FTSGTTGNPK GAMVTHRNIV SDCSAFVKAT ENTVNPCPDD TLISFLPLAH MFERVVECVM 
LCHGAKIGFF QGDIRLLMDD LKVLQPTVFP VVPRLLNRMF DRIFGQANTT LKRWLLDFAS 
KRKEAELRSG IIRNNSLWDR LIFHKVQSSL GGRVRLMVTG AAPVSATVLT FLRAALGCQF 
YEGYGQTECT AGCCLTMPGD WTAGHVGAPM PCNLIKLVDV EEMNYMAAEG EGEVCVKGPN 
VFQGYLKDPA KTAEALDKDG WLHTGDIGKW LPNGTLKIID RKKHIFKLAQ GEYIAPEKIE 
NIYMRSEPVA QVFVHGESLQ AFLIAIVVPD VETLCSWAQK RGFEGSFEEL CRNKDVKKAI 
LEDMVRLGKD SGLKPFEQVK GITLHPELFS IDNGLLTPTM KAKRPELRNY FRSQIDDLYS 
TIKV

Genular Protein ID: 753524793

Symbol: A8K9T3_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K9T3

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 42 DNASU 1 DisGeNET 1 EC 2 EMBL 2 GO 4 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 Pfam 2 RefSeq 5 Rhea 14 RuleBase 1 SUPFAM 1

Sequence Information:

  • Length: 698
  • Mass: 77952
  • Checksum: C8D996C0DD8974A8
  • Sequence:
    • MQAHELFRYF RMPELVDFRQ YVRTLPTNTL MGFGAFAALT TFWYATRPKP LKPPCDLSMQ 
SVEVAGSGGA RRSALLDSDE PLVYFYDDVT TLYEGFQRGI QVSNNGPCLG SRKPDQPYEW 
LSYKQVAELS ECIGSALIQK GFKTAPDQFI GIFAQNRPEW VIIEQGCFAY SMVIVPLYDT 
LGNEAITYIV NKAELSLVFV DKPEKAKLLL EGVENKLIPG LKIIVVMDAY GSELVERGHR 
CGVEVTSMKA MEDLGRANRR KPKPPAPEDL AVICFTSGTT GNPKGAMVTH RNIVSDCSAF 
VKATENTVNP CPDDTLISFL PLAHMFERVV ECVMLCHGAK IGFFQGDIRL LMDDLKVLQP 
TVFPVVPRLL NRMFDRIFGQ ANTTLKRWLL DFASKRKEAE LRSGIIRNNS LWDRLIFHKV 
QSSLGGRVRL MVTGAAPVSA TVLTFLRAAL GCQFYEGYGQ TECTAGCCLT MPGDWTAGHV 
GAPMPCNLIK LVDVEEMNYM AAEGEGEVCV KGPNVFQGYL KDPAKTAEAL DKDGWLHTGD 
IGKWLPNGTL KIIDRKKHIF KLAQGEYIAP EKIENIYMRS EPVAQVFVHG ESLQAFLIAI 
VVPDVETLCS WAQKRGFEGS FEELCRNKDV KKAILEDMVR LGKDSGLKPF EQVKGITLHP 
ELFSIDNGLL TPTMKAKRPE LRNYFRSQID DLYSTIKV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.