Details for: FASN

Gene ID: 2194

Symbol: FASN

Ensembl ID: ENSG00000169710

Description: fatty acid synthase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 135.9090
    Cell Significance Index: -21.1400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 81.3347
    Cell Significance Index: -20.6300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 44.4423
    Cell Significance Index: -18.0600
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 43.6738
    Cell Significance Index: 190.1200
  • Cell Name: sebaceous gland cell (CL2000021)
    Fold Change: 26.2325
    Cell Significance Index: 33.9400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 19.1465
    Cell Significance Index: -18.2800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 17.4053
    Cell Significance Index: -21.4600
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 8.3740
    Cell Significance Index: 51.5400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 8.0221
    Cell Significance Index: -21.4900
  • Cell Name: colon endothelial cell (CL1001572)
    Fold Change: 5.8044
    Cell Significance Index: 4.4300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.4903
    Cell Significance Index: -21.6700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 3.2431
    Cell Significance Index: 29.8700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 2.0149
    Cell Significance Index: 150.1700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.7205
    Cell Significance Index: 46.1000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.4581
    Cell Significance Index: 289.3600
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 1.0747
    Cell Significance Index: 13.8400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9882
    Cell Significance Index: 892.2700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.9847
    Cell Significance Index: 51.1500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.9483
    Cell Significance Index: 56.9300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.9358
    Cell Significance Index: 101.7900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.9338
    Cell Significance Index: 43.8900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8662
    Cell Significance Index: 140.8900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.8045
    Cell Significance Index: 56.9000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.7907
    Cell Significance Index: 142.5300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.7393
    Cell Significance Index: 403.7300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.6963
    Cell Significance Index: 9.5000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.6469
    Cell Significance Index: 18.0800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.6069
    Cell Significance Index: 17.4900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5542
    Cell Significance Index: 25.1200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.5318
    Cell Significance Index: 65.4000
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 0.4892
    Cell Significance Index: 6.1600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.4393
    Cell Significance Index: 88.1200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4167
    Cell Significance Index: 28.8200
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.3662
    Cell Significance Index: 3.7900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.3593
    Cell Significance Index: 9.7800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.3071
    Cell Significance Index: 39.6800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2885
    Cell Significance Index: 6.2500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2463
    Cell Significance Index: 108.9100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.2233
    Cell Significance Index: 11.6300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2009
    Cell Significance Index: 19.8700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.1973
    Cell Significance Index: 149.3200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1921
    Cell Significance Index: 68.9100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.1702
    Cell Significance Index: 4.8800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1645
    Cell Significance Index: 7.6700
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.1630
    Cell Significance Index: 2.7500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1489
    Cell Significance Index: 7.8200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1460
    Cell Significance Index: 27.7900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1189
    Cell Significance Index: 161.7100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1154
    Cell Significance Index: 15.8500
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.0859
    Cell Significance Index: 1.0700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0784
    Cell Significance Index: 1.6700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0583
    Cell Significance Index: 3.7600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0550
    Cell Significance Index: 1.1400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0171
    Cell Significance Index: 2.9200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0094
    Cell Significance Index: 14.4300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0076
    Cell Significance Index: 14.3400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0019
    Cell Significance Index: 0.0500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0009
    Cell Significance Index: 1.6800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0036
    Cell Significance Index: -0.2000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0066
    Cell Significance Index: -4.1400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0101
    Cell Significance Index: -7.4700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0125
    Cell Significance Index: -0.3300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0172
    Cell Significance Index: -10.9500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0176
    Cell Significance Index: -2.2600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0212
    Cell Significance Index: -15.5400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0266
    Cell Significance Index: -1.7900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0282
    Cell Significance Index: -15.9100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0385
    Cell Significance Index: -17.4700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0408
    Cell Significance Index: -4.8100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0564
    Cell Significance Index: -11.8700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0574
    Cell Significance Index: -16.5300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0654
    Cell Significance Index: -7.4900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0669
    Cell Significance Index: -4.1100
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.0866
    Cell Significance Index: -0.7200
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0874
    Cell Significance Index: -1.2900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1146
    Cell Significance Index: -11.7100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1172
    Cell Significance Index: -3.7600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1185
    Cell Significance Index: -13.8100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1187
    Cell Significance Index: -17.2600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1190
    Cell Significance Index: -2.0400
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.1236
    Cell Significance Index: -1.7600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1534
    Cell Significance Index: -9.6700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1590
    Cell Significance Index: -18.1500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1640
    Cell Significance Index: -3.5900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1717
    Cell Significance Index: -4.9000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1908
    Cell Significance Index: -11.7000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2036
    Cell Significance Index: -21.2000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2421
    Cell Significance Index: -18.5800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2424
    Cell Significance Index: -19.2000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2432
    Cell Significance Index: -8.4500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2743
    Cell Significance Index: -4.5900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.3143
    Cell Significance Index: -9.2300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.3234
    Cell Significance Index: -8.6500
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.3350
    Cell Significance Index: -3.4900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.3569
    Cell Significance Index: -7.4700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3640
    Cell Significance Index: -16.1000
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3782
    Cell Significance Index: -11.1400
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.3917
    Cell Significance Index: -6.0600
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.3935
    Cell Significance Index: -5.5200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4036
    Cell Significance Index: -10.0900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Multifunctional enzyme:** FASN is a multifunctional enzyme that catalyzes the synthesis of fatty acids from acetyl-CoA and malonyl-CoA. 2. **Highly expressed in lipid-synthesizing cells:** FASN is highly expressed in cells involved in lipid synthesis, including adipocytes, hepatocytes, and mammary gland cells. 3. **Regulated by SREBP:** FASN gene expression is regulated by SREBP, a transcription factor that plays a crucial role in lipid metabolism. 4. **Involved in various cellular processes:** FASN is involved in various cellular processes, including energy metabolism, inflammation, and cell differentiation. **Pathways and Functions:** FASN is involved in several cellular pathways, including: 1. **Fatty acid biosynthesis:** FASN catalyzes the synthesis of fatty acids from acetyl-CoA and malonyl-CoA. 2. **Lipid metabolism:** FASN plays a crucial role in lipid metabolism, including the synthesis of triglycerides and phospholipids. 3. **Energy metabolism:** FASN is involved in energy metabolism, including the synthesis of fatty acids and the regulation of glucose and lipid metabolism. 4. **Inflammation:** FASN is involved in inflammatory processes, including the synthesis of pro-inflammatory cytokines and the regulation of immune responses. 5. **Cell differentiation:** FASN plays a crucial role in cell differentiation, including the differentiation of adipocytes, hepatocytes, and mammary gland cells. **Clinical Significance:** Dysregulation of FASN gene expression has been implicated in various diseases, including: 1. **Obesity and metabolic disorders:** Overexpression of FASN has been linked to obesity and metabolic disorders, including insulin resistance and type 2 diabetes. 2. **Cancer:** FASN overexpression has been observed in various cancers, including breast, colon, and prostate cancer. 3. **Inflammatory diseases:** FASN is involved in inflammatory processes, and its dysregulation has been implicated in inflammatory diseases, including rheumatoid arthritis and atherosclerosis. 4. **Neurological disorders:** FASN has been implicated in neurological disorders, including Alzheimer's disease and Parkinson's disease. In conclusion, the FASN gene plays a crucial role in lipid metabolism and is involved in various cellular processes, including energy metabolism, inflammation, and cell differentiation. Dysregulation of FASN gene expression has been implicated in various diseases, and further research is needed to understand the mechanisms underlying FASN-mediated disease processes.

Genular Protein ID: 837790442

Symbol: FAS_HUMAN

Name: Fatty acid synthase

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7567999

Title: Human fatty acid synthase: properties and molecular cloning.

PubMed ID: 7567999

DOI: 10.1073/pnas.92.19.8695

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8022791

Title: Fatty acid synthesis: a potential selective target for antineoplastic therapy.

PubMed ID: 8022791

DOI: 10.1073/pnas.91.14.6379

PubMed ID: 7595075

Title: Human fatty acid synthase mRNA: tissue distribution, genetic mapping, and kinetics of decay after glucose deprivation.

PubMed ID: 7595075

PubMed ID: 8962082

Title: Cloning and expression of the multifunctional human fatty acid synthase and its subdomains in Escherichia coli.

PubMed ID: 8962082

DOI: 10.1073/pnas.93.25.14509

PubMed ID: 9356448

Title: Human fatty acid synthase: assembling recombinant halves of the fatty acid synthase subunit protein reconstitutes enzyme activity.

PubMed ID: 9356448

DOI: 10.1073/pnas.94.23.12326

PubMed ID: 16215233

Title: Substrate recognition by the human fatty-acid synthase.

PubMed ID: 16215233

DOI: 10.1074/jbc.m507082200

PubMed ID: 16969344

Title: Fatty acid synthase: a novel target for antiglioma therapy.

PubMed ID: 16969344

DOI: 10.1038/sj.bjc.6603350

PubMed ID: 26851298

Title: S-nitrosylation of fatty acid synthase regulates its activity through dimerization.

PubMed ID: 26851298

DOI: 10.1194/jlr.m065805

PubMed ID: 14654843

Title: Proteomic characterization of the human centrosome by protein correlation profiling.

PubMed ID: 14654843

DOI: 10.1038/nature02166

PubMed ID: 17081065

Title: Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.

PubMed ID: 17081065

DOI: 10.1021/pr060363j

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 34320401

Title: Inhibitors of VPS34 and fatty-acid metabolism suppress SARS-CoV-2 replication.

PubMed ID: 34320401

DOI: 10.1016/j.celrep.2021.109479

PubMed ID: 11756679

Title: Quaternary structure of human fatty acid synthase by electron cryomicroscopy.

PubMed ID: 11756679

DOI: 10.1073/pnas.012589499

PubMed ID: 15507492

Title: Human fatty acid synthase: structure and substrate selectivity of the thioesterase domain.

PubMed ID: 15507492

DOI: 10.1073/pnas.0406901101

PubMed ID: 18022563

Title: Mechanism and substrate recognition of human holo ACP synthase.

PubMed ID: 18022563

DOI: 10.1016/j.chembiol.2007.10.013

PubMed ID: 17618296

Title: Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by Orlistat.

PubMed ID: 17618296

DOI: 10.1038/nsmb1265

PubMed ID: 19549604

Title: Structural basis for different specificities of acyltransferases associated with the human cytosolic and mitochondrial fatty acid synthases.

PubMed ID: 19549604

DOI: 10.1016/j.chembiol.2009.04.011

PubMed ID: 28472301

Title: New gain-of-function mutation shows CACNA1D as recurrently mutated gene in autism spectrum disorders and epilepsy.

PubMed ID: 28472301

DOI: 10.1093/hmg/ddx175

Sequence Information:

  • Length: 2511
  • Mass: 273427
  • Checksum: 7A07171FEFA3287B
  • Sequence:
  • MEEVVIAGMS GKLPESENLQ EFWDNLIGGV DMVTDDDRRW KAGLYGLPRR SGKLKDLSRF 
    DASFFGVHPK QAHTMDPQLR LLLEVTYEAI VDGGINPDSL RGTHTGVWVG VSGSETSEAL 
    SRDPETLVGY SMVGCQRAMM ANRLSFFFDF RGPSIALDTA CSSSLMALQN AYQAIHSGQC 
    PAAIVGGINV LLKPNTSVQF LRLGMLSPEG TCKAFDTAGN GYCRSEGVVA VLLTKKSLAR 
    RVYATILNAG TNTDGFKEQG VTFPSGDIQE QLIRSLYQSA GVAPESFEYI EAHGTGTKVG 
    DPQELNGITR ALCATRQEPL LIGSTKSNMG HPEPASGLAA LAKVLLSLEH GLWAPNLHFH 
    SPNPEIPALL DGRLQVVDQP LPVRGGNVGI NSFGFGGSNV HIILRPNTQP PPAPAPHATL 
    PRLLRASGRT PEAVQKLLEQ GLRHSQDLAF LSMLNDIAAV PATAMPFRGY AVLGGERGGP 
    EVQQVPAGER PLWFICSGMG TQWRGMGLSL MRLDRFRDSI LRSDEAVKPF GLKVSQLLLS 
    TDESTFDDIV HSFVSLTAIQ IGLIDLLSCM GLRPDGIVGH SLGEVACGYA DGCLSQEEAV 
    LAAYWRGQCI KEAHLPPGAM AAVGLSWEEC KQRCPPGVVP ACHNSKDTVT ISGPQAPVFE 
    FVEQLRKEGV FAKEVRTGGM AFHSYFMEAI APPLLQELKK VIREPKPRSA RWLSTSIPEA 
    QWHSSLARTS SAEYNVNNLV SPVLFQEALW HVPEHAVVLE IAPHALLQAV LKRGLKPSCT 
    IIPLMKKDHR DNLEFFLAGI GRLHLSGIDA NPNALFPPVE FPAPRGTPLI SPLIKWDHSL 
    AWDVPAAEDF PNGSGSPSAA IYNIDTSSES PDHYLVDHTL DGRVLFPATG YLSIVWKTLA 
    RALGLGVEQL PVVFEDVVLH QATILPKTGT VSLEVRLLEA SRAFEVSENG NLVVSGKVYQ 
    WDDPDPRLFD HPESPTPNPT EPLFLAQAEV YKELRLRGYD YGPHFQGILE ASLEGDSGRL 
    LWKDNWVSFM DTMLQMSILG SAKHGLYLPT RVTAIHIDPA THRQKLYTLQ DKAQVADVVV 
    SRWLRVTVAG GVHISGLHTE SAPRRQQEQQ VPILEKFCFT PHTEEGCLSE RAALQEELQL 
    CKGLVQALQT KVTQQGLKMV VPGLDGAQIP RDPSQQELPR LLSAACRLQL NGNLQLELAQ 
    VLAQERPKLP EDPLLSGLLD SPALKACLDT AVENMPSLKM KVVEVLAGHG HLYSRIPGLL 
    SPHPLLQLSY TATDRHPQAL EAAQAELQQH DVAQGQWDPA DPAPSALGSA DLLVCNCAVA 
    ALGDPASALS NMVAALREGG FLLLHTLLRG HPLGDIVAFL TSTEPQYGQG ILSQDAWESL 
    FSRVSLRLVG LKKSFYGSTL FLCRRPTPQD SPIFLPVDDT SFRWVESLKG ILADEDSSRP 
    VWLKAINCAT SGVVGLVNCL RREPGGNRLR CVLLSNLSST SHVPEVDPGS AELQKVLQGD 
    LVMNVYRDGA WGAFRHFLLE EDKPEEPTAH AFVSTLTRGD LSSIRWVCSS LRHAQPTCPG 
    AQLCTVYYAS LNFRDIMLAT GKLSPDAIPG KWTSQDSLLG MEFSGRDASG KRVMGLVPAK 
    GLATSVLLSP DFLWDVPSNW TLEEAASVPV VYSTAYYALV VRGRVRPGET LLIHSGSGGV 
    GQAAIAIALS LGCRVFTTVG SAEKRAYLQA RFPQLDSTSF ANSRDTSFEQ HVLWHTGGKG 
    VDLVLNSLAE EKLQASVRCL ATHGRFLEIG KFDLSQNHPL GMAIFLKNVT FHGVLLDAFF 
    NESSADWREV WALVQAGIRD GVVRPLKCTV FHGAQVEDAF RYMAQGKHIG KVVVQVLAEE 
    PEAVLKGAKP KLMSAISKTF CPAHKSYIIA GGLGGFGLEL AQWLIQRGVQ KLVLTSRSGI 
    RTGYQAKQVR RWRRQGVQVQ VSTSNISSLE GARGLIAEAA QLGPVGGVFN LAVVLRDGLL 
    ENQTPEFFQD VCKPKYSGTL NLDRVTREAC PELDYFVVFS SVSCGRGNAG QSNYGFANSA 
    MERICEKRRH EGLPGLAVQW GAIGDVGILV ETMSTNDTIV SGTLPQRMAS CLEVLDLFLN 
    QPHMVLSSFV LAEKAAAYRD RDSQRDLVEA VAHILGIRDL AAVNLDSSLA DLGLDSLMSV 
    EVRQTLEREL NLVLSVREVR QLTLRKLQEL SSKADEASEL ACPTPKEDGL AQQQTQLNLR 
    SLLVNPEGPT LMRLNSVQSS ERPLFLVHPI EGSTTVFHSL ASRLSIPTYG LQCTRAAPLD 
    SIHSLAAYYI DCIRQVQPEG PYRVAGYSYG ACVAFEMCSQ LQAQQSPAPT HNSLFLFDGS 
    PTYVLAYTQS YRAKLTPGCE AEAETEAICF FVQQFTDMEH NRVLEALLPL KGLEERVAAA 
    VDLIIKSHQG LDRQELSFAA RSFYYKLRAA EQYTPKAKYH GNVMLLRAKT GGAYGEDLGA 
    DYNLSQVCDG KVSVHVIEGD HRTLLEGSGL ESIISIIHSS LAEPRVSVRE G

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.