Details for: FLT4

Gene ID: 2324

Symbol: FLT4

Ensembl ID: ENSG00000037280

Description: fms related receptor tyrosine kinase 4

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: endothelial cell of sinusoid (CL0002262)
    Fold Change: 1.66
    Marker Score: 402
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.14
    Marker Score: 2158
  • Cell Name: goblet cell (CL0000160)
    Fold Change: 1.14
    Marker Score: 7547
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.11
    Marker Score: 347
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 1.07
    Marker Score: 1005
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 1.04
    Marker Score: 793
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.03
    Marker Score: 9055
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.01
    Marker Score: 1076.5
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71826
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48051
  • Cell Name: endothelial tip cell (CL0000704)
    Fold Change: 0.99
    Marker Score: 231
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30408
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.97
    Marker Score: 2469
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.94
    Marker Score: 5346
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.92
    Marker Score: 2741
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 0.91
    Marker Score: 570
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5291
  • Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
    Fold Change: 0.84
    Marker Score: 1213
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1259
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.77
    Marker Score: 707
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.76
    Marker Score: 394
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.72
    Marker Score: 1471
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.69
    Marker Score: 176
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.67
    Marker Score: 404
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.63
    Marker Score: 9902
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.6
    Marker Score: 397
  • Cell Name: peritubular capillary endothelial cell (CL1001033)
    Fold Change: 0.58
    Marker Score: 136
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.56
    Marker Score: 444
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 0.53
    Marker Score: 1068
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.53
    Marker Score: 318
  • Cell Name: glomerular endothelial cell (CL0002188)
    Fold Change: 0.49
    Marker Score: 124
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.47
    Marker Score: 175
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.46
    Marker Score: 101
  • Cell Name: dermis microvascular lymphatic vessel endothelial cell (CL2000041)
    Fold Change: 0.46
    Marker Score: 149
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.44
    Marker Score: 390
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.43
    Marker Score: 415
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 0.4
    Marker Score: 109
  • Cell Name: vasa recta ascending limb cell (CL1001131)
    Fold Change: 0.36
    Marker Score: 95
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: 0.36
    Marker Score: 361
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: 0.36
    Marker Score: 382
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.35
    Marker Score: 166
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: 0.31
    Marker Score: 281
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.3
    Marker Score: 127
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: 0.29
    Marker Score: 249
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: 0.29
    Marker Score: 420
  • Cell Name: glomerular capillary endothelial cell (CL1001005)
    Fold Change: 0.28
    Marker Score: 78
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.28
    Marker Score: 73
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.27
    Marker Score: 630
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 0.27
    Marker Score: 77
  • Cell Name: naive regulatory T cell (CL0002677)
    Fold Change: 0.26
    Marker Score: 80
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.25
    Marker Score: 440
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 0.25
    Marker Score: 170
  • Cell Name: alveolar capillary type 1 endothelial cell (CL4028002)
    Fold Change: 0.25
    Marker Score: 633
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.23
    Marker Score: 100
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: 0.21
    Marker Score: 115
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.21
    Marker Score: 51
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: 0.21
    Marker Score: 188
  • Cell Name: Unknown (CL0000003)
    Fold Change: 0.2
    Marker Score: 630
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 0.19
    Marker Score: 264
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.18
    Marker Score: 59
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.18
    Marker Score: 1853
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.16
    Marker Score: 86
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.16
    Marker Score: 61
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: 0.16
    Marker Score: 66
  • Cell Name: erythroid lineage cell (CL0000764)
    Fold Change: 0.16
    Marker Score: 78
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 0.15
    Marker Score: 60
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 0.15
    Marker Score: 193
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 0.15
    Marker Score: 75
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 0.14
    Marker Score: 80
  • Cell Name: epithelial cell of glomerular capsule (CL1000450)
    Fold Change: 0.14
    Marker Score: 36
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.14
    Marker Score: 36
  • Cell Name: leukocyte (CL0000738)
    Fold Change: 0.14
    Marker Score: 78
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.13
    Marker Score: 263
  • Cell Name: memory T cell (CL0000813)
    Fold Change: 0.13
    Marker Score: 54
  • Cell Name: interstitial cell of Cajal (CL0002088)
    Fold Change: 0.12
    Marker Score: 42
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.12
    Marker Score: 205
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 0.12
    Marker Score: 23
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: 0.12
    Marker Score: 78
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 0.12
    Marker Score: 23.5
  • Cell Name: neuroendocrine cell (CL0000165)
    Fold Change: 0.12
    Marker Score: 45
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.12
    Marker Score: 128
  • Cell Name: blood vessel smooth muscle cell (CL0019018)
    Fold Change: 0.11
    Marker Score: 30
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.11
    Marker Score: 76
  • Cell Name: NKp44-negative group 3 innate lymphoid cell, human (CL0001080)
    Fold Change: 0.11
    Marker Score: 24.5
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.11
    Marker Score: 96
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.11
    Marker Score: 117
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: 0.11
    Marker Score: 86
  • Cell Name: mast cell (CL0000097)
    Fold Change: 0.11
    Marker Score: 63
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.11
    Marker Score: 96
  • Cell Name: effector CD4-positive, alpha-beta T cell (CL0001044)
    Fold Change: 0.11
    Marker Score: 100
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.11
    Marker Score: 72
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.1
    Marker Score: 53
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: 0.1
    Marker Score: 35
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 0.1
    Marker Score: 61
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 0.1
    Marker Score: 48
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.09
    Marker Score: 93
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.09
    Marker Score: 23
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 0.09
    Marker Score: 21
  • Cell Name: surface ectodermal cell (CL0000114)
    Fold Change: 0.09
    Marker Score: 32
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.09
    Marker Score: 1422

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Other Information

**Key characteristics:** * FLT4 is a transmembrane protein with a extracellular domain and a cytoplasmic domain. * It is expressed in a variety of cell types, including endothelial cells, cardiac endothelial cells, goblet cells, kidney capillary endothelial cells, type EC enteroendocrine cells, early T lineage precursor cells, and lung endothelial cells. * It is a key regulator of angiogenesis and cell growth. **Pathways and functions:** * FLT4 is a key regulator of angiogenesis. It is expressed in high levels in endothelial cells, which are the cells that line blood vessels. When FLT4 is activated, it promotes the migration and proliferation of endothelial cells, leading to the formation of new blood vessels. * FLT4 is also involved in cell growth and differentiation. It is expressed in a variety of cell types that are undergoing growth or differentiation, including endothelial cells, cardiac endothelial cells, and kidney capillary endothelial cells. * In addition to its role in angiogenesis and cell growth, FLT4 is also involved in a variety of other cellular processes, including cell migration, adhesion, and signaling. **Clinical significance:** * Mutations in the FLT4 gene have been linked to a number of human diseases, including cancer and vascular disease. * FLT4 inhibitors are being investigated as a treatment for cancer and other diseases that are characterized by angiogenesis and cell growth.

Genular Protein ID: 406481364

Symbol: VGFR3_HUMAN

Name: Vascular endothelial growth factor receptor 3

UniProtKB Accession Codes:

P35916 A8K6L4 B5A926 Q16067 Q86W07 Q86W08

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 4 CORUM 1 CTD 1 ChEBI 7 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 15 DrugCentral 1 EC 2 EMBL 9 Ensembl 2 ExpressionAtlas 1 GO 38 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 15 KEGG 1 MANE-Select 1 MIM 7 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 2 PIR 1 PIRSF 1 PRINTS 2 PRO 1 PROSITE 5 PROSITE-ProRule 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 2 RefSeq 2 Rhea 3 SAM 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1327515

Title: FLT4 receptor tyrosine kinase contains seven immunoglobulin-like loops and is expressed in multiple human tissues and cell lines.

PubMed ID: 1327515

PubMed ID: 1319394

Title: Chromosomal localization of FLT4, a novel receptor-type tyrosine kinase gene.

PubMed ID: 1319394

DOI: 10.1016/0888-7543(92)90277-y

PubMed ID: 8386825

Title: The FLT4 gene encodes a transmembrane tyrosine kinase related to the vascular endothelial growth factor receptor.

PubMed ID: 8386825

PubMed ID: 8700872

Title: Vascular endothelial growth factor-related protein: a ligand and specific activator of the tyrosine kinase receptor Flt4.

PubMed ID: 8700872

DOI: 10.1073/pnas.93.5.1988

PubMed ID: 18593464

Title: Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis.

PubMed ID: 18593464

DOI: 10.1186/ar2447

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 1310071

Title: FLT4, a novel class III receptor tyrosine kinase in chromosome 5q33-qter.

PubMed ID: 1310071

PubMed ID: 7692369

Title: Two human FLT4 receptor tyrosine kinase isoforms with distinct carboxy terminal tails are produced by alternative processing of primary transcripts.

PubMed ID: 7692369

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 7898938

Title: Biochemical characterization of two isoforms of FLT4, a VEGF receptor-related tyrosine kinase.

PubMed ID: 7898938

PubMed ID: 7675451

Title: Mutation at tyrosine residue 1337 abrogates ligand-dependent transforming capacity of the FLT4 receptor.

PubMed ID: 7675451

PubMed ID: 9435229

Title: Vascular endothelial growth factor D (VEGF-D) is a ligand for the tyrosine kinases VEGF receptor 2 (Flk1) and VEGF receptor 3 (Flt4).

PubMed ID: 9435229

DOI: 10.1073/pnas.95.2.548

PubMed ID: 11532940

Title: Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3.

PubMed ID: 11532940

DOI: 10.1093/emboj/20.17.4762

PubMed ID: 12881528

Title: Ligand-induced vascular endothelial growth factor receptor-3 (VEGFR-3) heterodimerization with VEGFR-2 in primary lymphatic endothelial cells regulates tyrosine phosphorylation sites.

PubMed ID: 12881528

DOI: 10.1074/jbc.m304499200

PubMed ID: 15474514

Title: Heterodimerization with vascular endothelial growth factor receptor-2 (VEGFR-2) is necessary for VEGFR-3 activity.

PubMed ID: 15474514

DOI: 10.1016/j.bbrc.2004.08.237

PubMed ID: 15102829

Title: Activation of vascular endothelial growth factor receptor-3 and its downstream signaling promote cell survival under oxidative stress.

PubMed ID: 15102829

DOI: 10.1074/jbc.m314015200

PubMed ID: 16076871

Title: Direct recruitment of CRK and GRB2 to VEGFR-3 induces proliferation, migration, and survival of endothelial cells through the activation of ERK, AKT, and JNK pathways.

PubMed ID: 16076871

DOI: 10.1182/blood-2005-04-1388

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 16452200

Title: Vascular endothelial growth factor receptor-3 and focal adhesion kinase bind and suppress apoptosis in breast cancer cells.

PubMed ID: 16452200

DOI: 10.1158/0008-5472.can-05-1661

PubMed ID: 17210781

Title: Cooperative and redundant roles of VEGFR-2 and VEGFR-3 signaling in adult lymphangiogenesis.

PubMed ID: 17210781

DOI: 10.1096/fj.06-6656com

PubMed ID: 19779139

Title: Autocrine loop between vascular endothelial growth factor (VEGF)-C and VEGF receptor-3 positively regulates tumor-associated lymphangiogenesis in oral squamoid cancer cells.

PubMed ID: 19779139

DOI: 10.2353/ajpath.2009.081139

PubMed ID: 19610651

Title: Small molecule chloropyramine hydrochloride (C4) targets the binding site of focal adhesion kinase and vascular endothelial growth factor receptor 3 and suppresses breast cancer growth in vivo.

PubMed ID: 19610651

DOI: 10.1021/jm900159g

PubMed ID: 20826270

Title: Protein tyrosine phosphatase PTPN14 is a regulator of lymphatic function and choanal development in humans.

PubMed ID: 20826270

DOI: 10.1016/j.ajhg.2010.08.008

PubMed ID: 20431062

Title: Endothelial cell adhesion to the extracellular matrix induces c-Src-dependent VEGFR-3 phosphorylation without the activation of the receptor intrinsic kinase activity.

PubMed ID: 20431062

DOI: 10.1161/circresaha.109.206326

PubMed ID: 20224550

Title: VEGF receptor 2/-3 heterodimers detected in situ by proximity ligation on angiogenic sprouts.

PubMed ID: 20224550

DOI: 10.1038/emboj.2010.30

PubMed ID: 20445537

Title: Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis.

PubMed ID: 20445537

DOI: 10.1038/nature09002

PubMed ID: 21273538

Title: Combined blockade of VEGFR-2 and VEGFR-3 inhibits inflammatory lymphangiogenesis in early and middle stages.

PubMed ID: 21273538

DOI: 10.1167/iovs.10-6408

PubMed ID: 18680722

Title: VEGF receptor protein-tyrosine kinases: structure and regulation.

PubMed ID: 18680722

DOI: 10.1016/j.bbrc.2008.07.121

PubMed ID: 19230644

Title: VEGFs and receptors involved in angiogenesis versus lymphangiogenesis.

PubMed ID: 19230644

DOI: 10.1016/j.ceb.2008.12.012

PubMed ID: 21711246

Title: Signal transduction by vascular endothelial growth factor receptors.

PubMed ID: 21711246

DOI: 10.1042/bj20110301

PubMed ID: 21196198

Title: Lymphangiogenesis and cancer metastasis.

PubMed ID: 21196198

DOI: 10.2741/3715

PubMed ID: 23878260

Title: Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation.

PubMed ID: 23878260

DOI: 10.1073/pnas.1301415110

PubMed ID: 9817924

Title: Hereditary lymphedema: evidence for linkage and genetic heterogeneity.

PubMed ID: 9817924

DOI: 10.1093/hmg/7.13.2073

PubMed ID: 10856194

Title: Congenital hereditary lymphedema caused by a mutation that inactivates VEGFR3 tyrosine kinase.

PubMed ID: 10856194

DOI: 10.1086/303019

PubMed ID: 10835628

Title: Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema.

PubMed ID: 10835628

DOI: 10.1038/75997

PubMed ID: 11807987

Title: Somatic mutation of vascular endothelial growth factor receptors in juvenile hemangioma.

PubMed ID: 11807987

DOI: 10.1002/gcc.10028

PubMed ID: 16965327

Title: Hereditary lymphedema type I associated with VEGFR3 mutation: the first de novo case and atypical presentations.

PubMed ID: 16965327

DOI: 10.1111/j.1399-0004.2006.00687.x

PubMed ID: 16924388

Title: Wide clinical spectrum in a family with hereditary lymphedema type I due to a novel missense mutation in VEGFR3.

PubMed ID: 16924388

DOI: 10.1007/s10038-006-0031-3

PubMed ID: 17458866

Title: A novel VEGFR3 mutation causes Milroy disease.

PubMed ID: 17458866

DOI: 10.1002/ajmg.a.31703

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

PubMed ID: 19289394

Title: Recessive primary congenital lymphoedema caused by a VEGFR3 mutation.

PubMed ID: 19289394

DOI: 10.1136/jmg.2008.064469

PubMed ID: 26091405

Title: A novel missense mutation in FLT4 causes autosomal recessive hereditary lymphedema.

PubMed ID: 26091405

DOI: 10.1089/lrb.2014.0044

PubMed ID: 28991257

Title: Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands.

PubMed ID: 28991257

DOI: 10.1038/ng.3970

PubMed ID: 30232381

Title: Haploinsufficiency of vascular endothelial growth factor related signaling genes is associated with tetralogy of Fallot.

PubMed ID: 30232381

DOI: 10.1038/s41436-018-0260-9

Sequence Information:

  • Length: 1363
  • Mass: 152757
  • Checksum: B1473AAAC95E7E93
  • Sequence:
    • MQRGAALCLR LWLCLGLLDG LVSGYSMTPP TLNITEESHV IDTGDSLSIS CRGQHPLEWA 
WPGAQEAPAT GDKDSEDTGV VRDCEGTDAR PYCKVLLLHE VHANDTGSYV CYYKYIKARI 
EGTTAASSYV FVRDFEQPFI NKPDTLLVNR KDAMWVPCLV SIPGLNVTLR SQSSVLWPDG 
QEVVWDDRRG MLVSTPLLHD ALYLQCETTW GDQDFLSNPF LVHITGNELY DIQLLPRKSL 
ELLVGEKLVL NCTVWAEFNS GVTFDWDYPG KQAERGKWVP ERRSQQTHTE LSSILTIHNV 
SQHDLGSYVC KANNGIQRFR ESTEVIVHEN PFISVEWLKG PILEATAGDE LVKLPVKLAA 
YPPPEFQWYK DGKALSGRHS PHALVLKEVT EASTGTYTLA LWNSAAGLRR NISLELVVNV 
PPQIHEKEAS SPSIYSRHSR QALTCTAYGV PLPLSIQWHW RPWTPCKMFA QRSLRRRQQQ 
DLMPQCRDWR AVTTQDAVNP IESLDTWTEF VEGKNKTVSK LVIQNANVSA MYKCVVSNKV 
GQDERLIYFY VTTIPDGFTI ESKPSEELLE GQPVLLSCQA DSYKYEHLRW YRLNLSTLHD 
AHGNPLLLDC KNVHLFATPL AASLEEVAPG ARHATLSLSI PRVAPEHEGH YVCEVQDRRS 
HDKHCHKKYL SVQALEAPRL TQNLTDLLVN VSDSLEMQCL VAGAHAPSIV WYKDERLLEE 
KSGVDLADSN QKLSIQRVRE EDAGRYLCSV CNAKGCVNSS ASVAVEGSED KGSMEIVILV 
GTGVIAVFFW VLLLLIFCNM RRPAHADIKT GYLSIIMDPG EVPLEEQCEY LSYDASQWEF 
PRERLHLGRV LGYGAFGKVV EASAFGIHKG SSCDTVAVKM LKEGATASEH RALMSELKIL 
IHIGNHLNVV NLLGACTKPQ GPLMVIVEFC KYGNLSNFLR AKRDAFSPCA EKSPEQRGRF 
RAMVELARLD RRRPGSSDRV LFARFSKTEG GARRASPDQE AEDLWLSPLT MEDLVCYSFQ 
VARGMEFLAS RKCIHRDLAA RNILLSESDV VKICDFGLAR DIYKDPDYVR KGSARLPLKW 
MAPESIFDKV YTTQSDVWSF GVLLWEIFSL GASPYPGVQI NEEFCQRLRD GTRMRAPELA 
TPAIRRIMLN CWSGDPKARP AFSELVEILG DLLQGRGLQE EEEVCMAPRS SQSSEEGSFS 
QVSTMALHIA QADAEDSPPS LQRHSLAARY YNWVSFPGCL ARGAETRGSS RMKTFEEFPM 
TPTTYKGSVD NQTDSGMVLA SEEFEQIESR HRQESGFSCK GPGQNVAVTR AHPDSQGRRR 
RPERGARGGQ VFYNSEYGEL SEPSEEDHCS PSARVTFFTD NSY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.