Details for: KAT2A

Gene ID: 2648

Symbol: KAT2A

Ensembl ID: ENSG00000108773

Description: lysine acetyltransferase 2A

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 126.1369
    Cell Significance Index: -19.6200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 70.4138
    Cell Significance Index: -17.8600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 46.9581
    Cell Significance Index: -22.1700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 42.0177
    Cell Significance Index: -17.0700
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 33.1509
    Cell Significance Index: -22.2500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 18.6595
    Cell Significance Index: -17.8200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 16.3834
    Cell Significance Index: -20.2000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 7.6899
    Cell Significance Index: -16.8300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.6077
    Cell Significance Index: -20.3800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.1697
    Cell Significance Index: -20.4000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 3.1491
    Cell Significance Index: 164.0300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.5192
    Cell Significance Index: 150.2800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.2184
    Cell Significance Index: 34.0500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.0330
    Cell Significance Index: 207.2200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.7728
    Cell Significance Index: 22.2700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7587
    Cell Significance Index: 123.3900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5520
    Cell Significance Index: 33.1400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.5487
    Cell Significance Index: 196.8200
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.5246
    Cell Significance Index: 12.8000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4252
    Cell Significance Index: 22.0900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4231
    Cell Significance Index: 382.0100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4205
    Cell Significance Index: 19.0600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3922
    Cell Significance Index: 77.8300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.3604
    Cell Significance Index: 18.9200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3527
    Cell Significance Index: 67.1300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.3476
    Cell Significance Index: 240.3900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.3283
    Cell Significance Index: 9.3700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3138
    Cell Significance Index: 21.7000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2260
    Cell Significance Index: 28.9700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2000
    Cell Significance Index: 27.4700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1782
    Cell Significance Index: 4.8500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1275
    Cell Significance Index: 16.4700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.1261
    Cell Significance Index: 1.7200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1139
    Cell Significance Index: 62.1900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.1118
    Cell Significance Index: 7.5200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0956
    Cell Significance Index: 6.1700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0746
    Cell Significance Index: 13.4400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0691
    Cell Significance Index: 5.3000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0631
    Cell Significance Index: 27.9200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0568
    Cell Significance Index: 2.6500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0549
    Cell Significance Index: 2.5800
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 0.0528
    Cell Significance Index: 0.2300
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 0.0458
    Cell Significance Index: 0.6400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0422
    Cell Significance Index: 1.1100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0318
    Cell Significance Index: 0.6600
  • Cell Name: slow muscle cell (CL0000189)
    Fold Change: 0.0207
    Cell Significance Index: 0.3100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0203
    Cell Significance Index: 2.4900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0161
    Cell Significance Index: 30.2700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0102
    Cell Significance Index: 0.3600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0023
    Cell Significance Index: 4.2900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0001
    Cell Significance Index: -0.0900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0020
    Cell Significance Index: -0.3500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0032
    Cell Significance Index: -0.1400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0067
    Cell Significance Index: -9.0900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0068
    Cell Significance Index: -4.3000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0119
    Cell Significance Index: -8.7500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0139
    Cell Significance Index: -10.5300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0220
    Cell Significance Index: -9.9900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0269
    Cell Significance Index: -19.9600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0329
    Cell Significance Index: -18.5600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0355
    Cell Significance Index: -4.1900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0368
    Cell Significance Index: -23.0000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0486
    Cell Significance Index: -4.9600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0495
    Cell Significance Index: -7.1900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0503
    Cell Significance Index: -1.0900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0550
    Cell Significance Index: -1.9100
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.0586
    Cell Significance Index: -0.7500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0656
    Cell Significance Index: -7.5200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0704
    Cell Significance Index: -20.2500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0717
    Cell Significance Index: -1.2000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0729
    Cell Significance Index: -2.7600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0976
    Cell Significance Index: -11.3700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0998
    Cell Significance Index: -7.4400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1104
    Cell Significance Index: -23.2600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1345
    Cell Significance Index: -9.5100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1609
    Cell Significance Index: -4.1100
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: -0.1624
    Cell Significance Index: -2.6200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1667
    Cell Significance Index: -3.5500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1708
    Cell Significance Index: -5.4700
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1806
    Cell Significance Index: -1.8700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1858
    Cell Significance Index: -11.3900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1873
    Cell Significance Index: -19.5000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1897
    Cell Significance Index: -11.6600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1932
    Cell Significance Index: -5.1600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2037
    Cell Significance Index: -5.8400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2121
    Cell Significance Index: -13.3700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2252
    Cell Significance Index: -6.0300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.2253
    Cell Significance Index: -4.8200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2328
    Cell Significance Index: -4.9400
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.2337
    Cell Significance Index: -4.0400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2369
    Cell Significance Index: -4.0600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2381
    Cell Significance Index: -18.8600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2449
    Cell Significance Index: -13.7400
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.3285
    Cell Significance Index: -4.9500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3291
    Cell Significance Index: -10.4800
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.3621
    Cell Significance Index: -7.1600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3645
    Cell Significance Index: -9.3700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3845
    Cell Significance Index: -12.5900
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.3879
    Cell Significance Index: -8.3800
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.4034
    Cell Significance Index: -5.0900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** KAT2A is a member of the HAT family, which acetylates lysine residues on histone tails, leading to the relaxation of chromatin structure and enhanced transcriptional activity. The enzyme exhibits high specificity for histone H3 and H4, with a preference for acetylating lysines 9, 12, 18, and 27. KAT2A also exhibits non-histone protein acetyltransferase activity, which allows it to modify other proteins, including transcription factors and signaling molecules. **Pathways and Functions** KAT2A is involved in various signaling pathways, including: 1. **Notch signaling**: KAT2A regulates Notch signaling by acetylating Notch receptors and their intracellular domains, leading to the activation of transcriptional targets. 2. **Cell differentiation**: KAT2A plays a crucial role in the regulation of cell differentiation, particularly in the development of the nervous system, where it acetylates histones to promote the expression of genes involved in neural development. 3. **Transcriptional regulation**: KAT2A acts as a transcriptional coactivator, enhancing the activity of transcription factors and RNA polymerase II to regulate gene expression. 4. **Cell cycle regulation**: KAT2A regulates cell cycle progression by acetylating histones to promote the expression of genes involved in cell cycle progression. **Clinical Significance** Dysregulation of KAT2A has been implicated in various diseases, including: 1. **Cancer**: Overexpression of KAT2A has been observed in several types of cancer, including breast, lung, and colon cancer, where it contributes to the regulation of cell proliferation and survival. 2. **Neurological disorders**: KAT2A has been implicated in the regulation of gene expression in neurological disorders, such as Alzheimer's disease and Parkinson's disease, where it plays a role in the regulation of transcriptional programs involved in neuronal function and survival. 3. **Developmental disorders**: KAT2A has been implicated in the regulation of gene expression during embryonic development, where it plays a role in the regulation of transcriptional programs involved in cell differentiation and patterning. In conclusion, KAT2A is a multifunctional enzyme involved in the regulation of gene expression through the acetylation of histones and non-histone proteins. Its dysregulation has been implicated in various diseases, highlighting the importance of KAT2A in maintaining cellular homeostasis and regulating cellular processes.

Genular Protein ID: 2762387134

Symbol: KAT2A_HUMAN

Name: Histone acetyltransferase KAT2A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8552087

Title: Identification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5.

PubMed ID: 8552087

DOI: 10.1128/mcb.16.2.593

PubMed ID: 9611240

Title: Cloning of Drosophila GCN5: conserved features among metazoan GCN5 family members.

PubMed ID: 9611240

DOI: 10.1093/nar/26.12.2948

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8684459

Title: A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A.

PubMed ID: 8684459

DOI: 10.1038/382319a0

PubMed ID: 11564863

Title: Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo.

PubMed ID: 11564863

DOI: 10.1128/mcb.21.20.6782-6795.2001

PubMed ID: 10373431

Title: Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction.

PubMed ID: 10373431

DOI: 10.1074/jbc.274.26.18285

PubMed ID: 10611234

Title: The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc.

PubMed ID: 10611234

DOI: 10.1128/mcb.20.2.556-562.2000

PubMed ID: 11384967

Title: The histone acetyltransferase, hGCN5, interacts with and acetylates the HIV transactivator, Tat.

PubMed ID: 11384967

DOI: 10.1074/jbc.m101385200

PubMed ID: 11438666

Title: The TFIID components human TAFII140 and Drosophila BIP2 (TAFII155) are novel metazoan homologues of yeast TAFII47 containing a histone fold and a PHD finger.

PubMed ID: 11438666

DOI: 10.1128/mcb.21.15.5109-5121.2001

PubMed ID: 14767476

Title: The transforming acidic coiled coil proteins interact with nuclear histone acetyltransferases.

PubMed ID: 14767476

DOI: 10.1038/sj.onc.1207424

PubMed ID: 15592455

Title: Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

PubMed ID: 15592455

DOI: 10.1038/nbt1046

PubMed ID: 16753578

Title: GCN5 acetyltransferase complex controls glucose metabolism through transcriptional repression of PGC-1alpha.

PubMed ID: 16753578

DOI: 10.1016/j.cmet.2006.04.013

PubMed ID: 17301242

Title: Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPbeta by GCN5.

PubMed ID: 17301242

DOI: 10.1073/pnas.0607378104

PubMed ID: 18206972

Title: A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.

PubMed ID: 18206972

DOI: 10.1016/j.molcel.2007.12.011

PubMed ID: 19103755

Title: The double-histone-acetyltransferase complex ATAC is essential for mammalian development.

PubMed ID: 19103755

DOI: 10.1128/mcb.01599-08

PubMed ID: 21131905

Title: Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation.

PubMed ID: 21131905

DOI: 10.1038/emboj.2010.318

PubMed ID: 23142079

Title: The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis.

PubMed ID: 23142079

DOI: 10.1016/j.molcel.2012.09.030

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 25593309

Title: Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

PubMed ID: 25593309

DOI: 10.1101/gad.252189.114

PubMed ID: 27796307

Title: KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification.

PubMed ID: 27796307

DOI: 10.1038/ncomms13227

PubMed ID: 29174768

Title: Acetylation of TBX5 by KAT2B and KAT2A regulates heart and limb development.

PubMed ID: 29174768

DOI: 10.1016/j.yjmcc.2017.11.013

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 30109122

Title: Supramolecular assembly of KAT2A with succinyl-CoA for histone succinylation.

PubMed ID: 30109122

DOI: 10.1038/s41421-018-0048-8

PubMed ID: 29973595

Title: XPC is an RNA polymerase II cofactor recruiting ATAC to promoters by interacting with E2F1.

PubMed ID: 29973595

DOI: 10.1038/s41467-018-05010-0

PubMed ID: 31542297

Title: Glutarylation of histone H4 lysine 91 regulates chromatin dynamics.

PubMed ID: 31542297

DOI: 10.1016/j.molcel.2019.08.018

PubMed ID: 31527837

Title: DNA repair complex licenses acetylation of H2A.Z.1 by KAT2A during transcription.

PubMed ID: 31527837

DOI: 10.1038/s41589-019-0354-y

PubMed ID: 30894545

Title: Functional interplay between TFIIH and KAT2A regulates higher-order chromatin structure and class II gene expression.

PubMed ID: 30894545

DOI: 10.1038/s41467-019-09270-2

PubMed ID: 35995428

Title: The Acyl-CoA Specificity of Human Lysine Acetyltransferase KAT2A.

PubMed ID: 35995428

DOI: 10.1021/acs.biochem.2c00308

PubMed ID: 38128537

Title: Metabolic regulation of homologous recombination repair by MRE11 lactylation.

PubMed ID: 38128537

DOI: 10.1016/j.cell.2023.11.022

PubMed ID: 11090279

Title: Solution structure and acetyl-lysine binding activity of the GCN5 bromodomain.

PubMed ID: 11090279

DOI: 10.1006/jmbi.2000.4207

PubMed ID: 17410582

Title: Crystal structure of a binary complex between human GCN5 histone acetyltransferase domain and acetyl coenzyme A.

PubMed ID: 17410582

DOI: 10.1002/prot.21407

PubMed ID: 22464331

Title: Histone recognition and large-scale structural analysis of the human bromodomain family.

PubMed ID: 22464331

DOI: 10.1016/j.cell.2012.02.013

PubMed ID: 27377381

Title: Structural basis for acyl-group discrimination by human Gcn5L2.

PubMed ID: 27377381

DOI: 10.1107/s2059798316007907

PubMed ID: 29211711

Title: KAT2A coupled with the alpha-KGDH complex acts as a histone H3 succinyltransferase.

PubMed ID: 29211711

DOI: 10.1038/nature25003

Sequence Information:

  • Length: 837
  • Mass: 93926
  • Checksum: 728CC8ACF08600EA
  • Sequence:
  • MAEPSQAPTP APAAQPRPLQ SPAPAPTPTP APSPASAPIP TPTPAPAPAP AAAPAGSTGT 
    GGPGVGSGGA GSGGDPARPG LSQQQRASQR KAQVRGLPRA KKLEKLGVFS ACKANETCKC 
    NGWKNPKPPT APRMDLQQPA ANLSELCRSC EHPLADHVSH LENVSEDEIN RLLGMVVDVE 
    NLFMSVHKEE DTDTKQVYFY LFKLLRKCIL QMTRPVVEGS LGSPPFEKPN IEQGVLNFVQ 
    YKFSHLAPRE RQTMFELSKM FLLCLNYWKL ETPAQFRQRS QAEDVATYKV NYTRWLCYCH 
    VPQSCDSLPR YETTHVFGRS LLRSIFTVTR RQLLEKFRVE KDKLVPEKRT LILTHFPKFL 
    SMLEEEIYGA NSPIWESGFT MPPSEGTQLV PRPASVSAAV VPSTPIFSPS MGGGSNSSLS 
    LDSAGAEPMP GEKRTLPENL TLEDAKRLRV MGDIPMELVN EVMLTITDPA AMLGPETSLL 
    SANAARDETA RLEERRGIIE FHVIGNSLTP KANRRVLLWL VGLQNVFSHQ LPRMPKEYIA 
    RLVFDPKHKT LALIKDGRVI GGICFRMFPT QGFTEIVFCA VTSNEQVKGY GTHLMNHLKE 
    YHIKHNILYF LTYADEYAIG YFKKQGFSKD IKVPKSRYLG YIKDYEGATL MECELNPRIP 
    YTELSHIIKK QKEIIKKLIE RKQAQIRKVY PGLSCFKEGV RQIPVESVPG IRETGWKPLG 
    KEKGKELKDP DQLYTTLKNL LAQIKSHPSA WPFMEPVKKS EAPDYYEVIR FPIDLKTMTE 
    RLRSRYYVTR KLFVADLQRV IANCREYNPP DSEYCRCASA LEKFFYFKLK EGGLIDK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.