Details for: BRPF3
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 92.5133
Cell Significance Index: -14.3900 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 59.6901
Cell Significance Index: -15.1400 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 34.0801
Cell Significance Index: -16.0900 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 33.4517
Cell Significance Index: -13.5900 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 23.9187
Cell Significance Index: -16.0500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 14.2761
Cell Significance Index: -13.6300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 12.4092
Cell Significance Index: -15.3000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 3.9102
Cell Significance Index: -15.4300 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 2.4171
Cell Significance Index: -5.2900 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 2.2215
Cell Significance Index: 59.5300 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.2485
Cell Significance Index: 74.9600 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.2203
Cell Significance Index: 16.6500 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.1387
Cell Significance Index: 123.8600 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.9317
Cell Significance Index: 42.2300 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.8997
Cell Significance Index: 146.3300 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.8851
Cell Significance Index: 799.1600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.8347
Cell Significance Index: 165.6500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.7338
Cell Significance Index: 147.1900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.4998
Cell Significance Index: 14.4000 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 0.4926
Cell Significance Index: 6.9100 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 0.4431
Cell Significance Index: 6.6400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.3697
Cell Significance Index: 8.0100 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 0.3426
Cell Significance Index: 3.6400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.2935
Cell Significance Index: 16.4700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2699
Cell Significance Index: 96.8100 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.2563
Cell Significance Index: 13.3500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.2555
Cell Significance Index: 13.2700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.2436
Cell Significance Index: 43.9100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.2329
Cell Significance Index: 14.6800 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.2211
Cell Significance Index: 10.3100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.2101
Cell Significance Index: 20.7800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.2057
Cell Significance Index: 5.6000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1755
Cell Significance Index: 33.3900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.1602
Cell Significance Index: 19.6900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.1228
Cell Significance Index: 3.0700 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.1118
Cell Significance Index: 61.0400 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1095
Cell Significance Index: 18.7000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1042
Cell Significance Index: 14.3100 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0981
Cell Significance Index: 67.8500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0774
Cell Significance Index: 2.7200 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.0732
Cell Significance Index: 1.9300 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0703
Cell Significance Index: 31.0900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.0593
Cell Significance Index: 6.7900 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0531
Cell Significance Index: 1.1300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0490
Cell Significance Index: 3.0100 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0189
Cell Significance Index: 2.4200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0145
Cell Significance Index: 1.1100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.0082
Cell Significance Index: 0.5500 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.0058
Cell Significance Index: 0.1600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0021
Cell Significance Index: -3.9200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0027
Cell Significance Index: -1.9700 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0027
Cell Significance Index: -0.1200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0054
Cell Significance Index: -3.3600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0063
Cell Significance Index: -11.6000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0072
Cell Significance Index: -11.0200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0080
Cell Significance Index: -5.0500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0087
Cell Significance Index: -6.4100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0094
Cell Significance Index: -12.8200 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0103
Cell Significance Index: -0.3300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0126
Cell Significance Index: -7.1100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0137
Cell Significance Index: -10.3900 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0140
Cell Significance Index: -0.2900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0147
Cell Significance Index: -6.6900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0150
Cell Significance Index: -0.4000 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0215
Cell Significance Index: -1.0100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0283
Cell Significance Index: -0.7900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0319
Cell Significance Index: -4.6400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0385
Cell Significance Index: -8.1100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0416
Cell Significance Index: -11.9600 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0418
Cell Significance Index: -1.5800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0541
Cell Significance Index: -6.3000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0599
Cell Significance Index: -6.1200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0611
Cell Significance Index: -7.2100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0627
Cell Significance Index: -1.0500 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0632
Cell Significance Index: -8.1700 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0724
Cell Significance Index: -8.2600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0883
Cell Significance Index: -6.5800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0959
Cell Significance Index: -6.1900 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1076
Cell Significance Index: -7.6100 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.1439
Cell Significance Index: -3.1500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1449
Cell Significance Index: -15.0900 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.1584
Cell Significance Index: -3.8000 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1672
Cell Significance Index: -13.2400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1720
Cell Significance Index: -4.4200 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.1724
Cell Significance Index: -1.7900 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.2050
Cell Significance Index: -5.8500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.2060
Cell Significance Index: -10.8200 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.2077
Cell Significance Index: -2.9800 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.2093
Cell Significance Index: -2.6800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.2166
Cell Significance Index: -13.2800 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.2235
Cell Significance Index: -3.8300 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.2305
Cell Significance Index: -7.3400 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.2396
Cell Significance Index: -3.6100 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.2412
Cell Significance Index: -8.3800 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.2540
Cell Significance Index: -5.3900 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2566
Cell Significance Index: -8.4000 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2613
Cell Significance Index: -5.1000 - Cell Name: proerythroblast (CL0000547)
Fold Change: -0.2735
Cell Significance Index: -3.9200 - Cell Name: peg cell (CL4033014)
Fold Change: -0.2926
Cell Significance Index: -6.7600 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.3093
Cell Significance Index: -6.1200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3571655482
Symbol: BRPF3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10574462
Title: Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10574462
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 16387653
Title: ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.
PubMed ID: 16387653
PubMed ID: 18794358
Title: Molecular architecture of quartet MOZ/MORF histone acetyltransferase complexes.
PubMed ID: 18794358
DOI: 10.1128/mcb.01297-08
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25593309
Title: Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.
PubMed ID: 25593309
PubMed ID: 26620551
Title: BRPF3-HBO1 regulates replication origin activation and histone H3K14 acetylation.
PubMed ID: 26620551
PubMed ID: 26677226
Title: The chromatin regulator BRPF3 preferentially activates the HBO1 acetyltransferase but is dispensable for mouse development and survival.
PubMed ID: 26677226
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 21720545
Title: Structural and histone binding ability characterizations of human PWWP domains.
PubMed ID: 21720545
Sequence Information:
- Length: 1205
- Mass: 135745
- Checksum: F51DCAB253ED35C7
- Sequence:
MRKPRRKSRQ NAEGRRSPSP YSLKCSPTRE TLTYAQAQRI VEVDIDGRLH RISIYDPLKI ITEDELTAQD ITECNSNKEN SEQPQFPGKS KKPSSKGKKK ESCSKHASGT SFHLPQPSFR MVDSGIQPEA PPLPAAYYRY IEKPPEDLDA EVEYDMDEED LAWLDMVNEK RRVDGHSLVS ADTFELLVDR LEKESYLESR SSGAQQSLID EDAFCCVCLD DECHNSNVIL FCDICNLAVH QECYGVPYIP EGQWLCRCCL QSPSRPVDCI LCPNKGGAFK QTSDGHWAHV VCAIWIPEVC FANTVFLEPI EGIDNIPPAR WKLTCYICKQ KGLGAAIQCH KVNCYTAFHV TCAQRAGLFM KIEPMRETSL NGTIFTVRKT AYCEAHSPPG AATARRKGDS PRSISETGDE EGLKEGDGEE EEEEEVEEEE QEAQGGVSGS LKGVPKKSKM SLKQKIKKEP EEAGQDTPST LPMLAVPQIP SYRLNKICSG LSFQRKNQFM QRLHNYWLLK RQARNGVPLI RRLHSHLQSQ RNAEQREQDE KTSAVKEELK YWQKLRHDLE RARLLIELIR KREKLKREQV KVQQAAMELE LMPFNVLLRT TLDLLQEKDP AHIFAEPVNL SEVPDYLEFI SKPMDFSTMR RKLESHLYRT LEEFEEDFNL IVTNCMKYNA KDTIFHRAAV RLRDLGGAIL RHARRQAENI GYDPERGTHL PESPKLEDFY RFSWEDVDNI LIPENRAHLS PEVQLKELLE KLDLVSAMRS SGARTRRVRL LRREINALRQ KLAQPPPPQP PSLNKTVSNG ELPAGPQGDA AVLEQALQEE PEDDGDRDDS KLPPPPTLEP TGPAPSLSEQ ESPPEPPTLK PINDSKPPSR FLKPRKVEED ELLEKSPLQL GNEPLQRLLS DNGINRLSLM APDTPAGTPL SGVGRRTSVL FKKAKNGVKL QRSPDRVLEN GEDHGVAGSP ASPASIEEER HSRKRPRSRS CSESEGERSP QQEEETGMTN GFGKHTESGS DSECSLGLSG GLAFEACSGL TPPKRSRGKP ALSRVPFLEG VNGDSDYNGS GRSLLLPFED RGDLEPLELV WAKCRGYPSY PALIIDPKMP REGLLHNGVP IPVPPLDVLK LGEQKQAEAG EKLFLVLFFD NKRTWQWLPR DKVLPLGVED TVDKLKMLEG RKTSIRKSVQ VAYDRAMIHL SRVRGPHSFV TSSYL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.