Details for: RABGEF1

Gene ID: 27342

Symbol: RABGEF1

Ensembl ID: ENSG00000154710

Description: RAB guanine nucleotide exchange factor 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 194.9915
    Cell Significance Index: -30.3300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 120.7207
    Cell Significance Index: -30.6200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 24.8346
    Cell Significance Index: -30.6200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 7.7901
    Cell Significance Index: -30.7400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.0026
    Cell Significance Index: -8.7600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 3.1076
    Cell Significance Index: 174.3900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.6515
    Cell Significance Index: 531.8800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.3146
    Cell Significance Index: 830.2100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 2.2396
    Cell Significance Index: 60.0100
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 2.2165
    Cell Significance Index: 22.3600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 2.1607
    Cell Significance Index: 51.8200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 2.1454
    Cell Significance Index: 53.6300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.9526
    Cell Significance Index: 86.3700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.9269
    Cell Significance Index: 72.9700
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.9112
    Cell Significance Index: 23.7100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.8272
    Cell Significance Index: 112.3100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.7695
    Cell Significance Index: 38.7500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.3718
    Cell Significance Index: 94.8700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.3487
    Cell Significance Index: 103.5000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 1.2864
    Cell Significance Index: 65.0100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.1749
    Cell Significance Index: 33.6800
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: 1.0753
    Cell Significance Index: 4.9700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.8623
    Cell Significance Index: 24.8500
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.6955
    Cell Significance Index: 10.7600
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 0.6874
    Cell Significance Index: 7.1600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6836
    Cell Significance Index: 41.0400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6693
    Cell Significance Index: 604.3600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.5737
    Cell Significance Index: 36.1600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5340
    Cell Significance Index: 58.0900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4682
    Cell Significance Index: 84.4100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4483
    Cell Significance Index: 23.2900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4471
    Cell Significance Index: 54.9800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.4170
    Cell Significance Index: 18.9000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3780
    Cell Significance Index: 61.4800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.3613
    Cell Significance Index: 4.9300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.3603
    Cell Significance Index: 16.9400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3573
    Cell Significance Index: 7.7400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.3048
    Cell Significance Index: 10.7100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.2570
    Cell Significance Index: 4.7500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1388
    Cell Significance Index: 26.4100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1345
    Cell Significance Index: 3.6600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1098
    Cell Significance Index: 10.8600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0639
    Cell Significance Index: 28.2500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0564
    Cell Significance Index: 7.7500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0457
    Cell Significance Index: 24.9600
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 0.0212
    Cell Significance Index: 0.4500
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 0.0131
    Cell Significance Index: 0.2600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0053
    Cell Significance Index: 0.6300
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0071
    Cell Significance Index: -13.2900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0079
    Cell Significance Index: -0.2100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0144
    Cell Significance Index: -26.4800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0180
    Cell Significance Index: -27.7000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0191
    Cell Significance Index: -14.1600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0230
    Cell Significance Index: -31.2300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0263
    Cell Significance Index: -19.3200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0333
    Cell Significance Index: -21.1800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0336
    Cell Significance Index: -18.9400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0344
    Cell Significance Index: -26.0300
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0393
    Cell Significance Index: -0.6800
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.0413
    Cell Significance Index: -0.3800
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.0447
    Cell Significance Index: -0.2700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0523
    Cell Significance Index: -32.6300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0541
    Cell Significance Index: -24.5500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0854
    Cell Significance Index: -11.0300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0895
    Cell Significance Index: -25.7500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0904
    Cell Significance Index: -10.5300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0906
    Cell Significance Index: -11.6200
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1056
    Cell Significance Index: -2.1200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1077
    Cell Significance Index: -3.4500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1168
    Cell Significance Index: -16.9800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1177
    Cell Significance Index: -20.0900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1224
    Cell Significance Index: -25.7800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.1242
    Cell Significance Index: -24.6400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1453
    Cell Significance Index: -14.8500
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.1481
    Cell Significance Index: -0.9300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1599
    Cell Significance Index: -2.2900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1604
    Cell Significance Index: -5.2500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1736
    Cell Significance Index: -12.9400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1755
    Cell Significance Index: -5.5900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1929
    Cell Significance Index: -22.1000
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.2092
    Cell Significance Index: -2.6400
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.2297
    Cell Significance Index: -4.9100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2324
    Cell Significance Index: -15.0000
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.2328
    Cell Significance Index: -5.0300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2842
    Cell Significance Index: -20.1000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.2865
    Cell Significance Index: -3.4200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2974
    Cell Significance Index: -30.9700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3049
    Cell Significance Index: -24.1500
  • Cell Name: chandelier cell (CL4023083)
    Fold Change: -0.3319
    Cell Significance Index: -2.6800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.3331
    Cell Significance Index: -15.5300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3371
    Cell Significance Index: -20.6700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3535
    Cell Significance Index: -23.7700
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: -0.3550
    Cell Significance Index: -2.1900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.3627
    Cell Significance Index: -5.4400
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.3752
    Cell Significance Index: -9.3600
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.3774
    Cell Significance Index: -3.0800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.3857
    Cell Significance Index: -10.7800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.3893
    Cell Significance Index: -8.2900
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.3918
    Cell Significance Index: -2.3300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RABGEF1 is a GEF for the RAB proteins, which are small GTPases that regulate membrane trafficking and endocytosis. The RABGEF1 protein has been shown to interact with various RAB proteins, including RAB5, RAB7, and RAB11, facilitating their activation and subsequent participation in downstream signaling events. RABGEF1 has also been implicated in the regulation of signaling pathways, including the Kit signaling pathway, mast cell degranulation, and leukocyte migration. In terms of its expression profile, RABGEF1 is significantly expressed in multiple cell types, including mesangial cells, kidney proximal convoluted tubule epithelial cells, and GABAergic cortical interneurons. This suggests that RABGEF1 plays a critical role in regulating cellular processes in these cell types. **Pathways and Functions:** RABGEF1 is involved in various cellular processes, including: 1. **Membrane Trafficking:** RABGEF1 facilitates the exchange of GDP for GTP on RAB proteins, promoting their activation and subsequent participation in downstream signaling events. This leads to the regulation of membrane trafficking, including endocytosis and exocytosis. 2. **Endocytic Vesicle Formation:** RABGEF1 has been shown to regulate the formation of endocytic vesicles, including early endosomes and late endosomes. 3. **Signaling Pathways:** RABGEF1 is involved in the regulation of various signaling pathways, including the Kit signaling pathway, mast cell degranulation, and leukocyte migration. 4. **Protein Trafficking:** RABGEF1 regulates the trafficking of proteins to the cell surface and to intracellular compartments. 5. **Regulation of Inflammatory Response:** RABGEF1 has been shown to negatively regulate the inflammatory response by inhibiting the production of pro-inflammatory cytokines. **Clinical Significance:** RABGEF1 has been implicated in various diseases, including: 1. **Cancer:** RABGEF1 has been shown to regulate the trafficking of proteins involved in cancer cell migration and invasion. 2. **Neurodegenerative Diseases:** RABGEF1 has been implicated in the regulation of protein trafficking in neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. 3. **Inflammatory Diseases:** RABGEF1 has been shown to regulate the inflammatory response in diseases such as rheumatoid arthritis and asthma. 4. **Cardiovascular Diseases:** RABGEF1 has been implicated in the regulation of protein trafficking in cardiovascular diseases, including atherosclerosis and hypertension. In conclusion, RABGEF1 is a multifaceted gene involved in regulating various cellular processes through guanine nucleotide exchange factor activity. Its dysregulation has been implicated in various diseases, highlighting the need for further research into its role in human health and disease.

Genular Protein ID: 3931592689

Symbol: RABX5_HUMAN

Name: Rab5 GDP/GTP exchange factor

UniProtKB Accession Codes:

Q9UJ41 B4DZM7 Q3HKR2 Q3HKR3 Q53FG0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChEBI 4 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 10 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 31 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 8 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 4 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11098082

Title: Seven genes that are differentially transcribed in colorectal tumor cell lines.

PubMed ID: 11098082

DOI: 10.1016/s0304-3835(00)00553-x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9323142

Title: A novel Rab5 GDP/GTP exchange factor complexed to Rabaptin-5 links nucleotide exchange to effector recruitment and function.

PubMed ID: 9323142

DOI: 10.1016/s0092-8674(00)80380-3

PubMed ID: 11452015

Title: Functional synergy between Rab5 effector Rabaptin-5 and exchange factor Rabex-5 when physically associated in a complex.

PubMed ID: 11452015

DOI: 10.1091/mbc.12.7.2219

PubMed ID: 12505986

Title: Divalent interaction of the GGAs with the Rabaptin-5-Rabex-5 complex.

PubMed ID: 12505986

DOI: 10.1093/emboj/cdg015

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 15339665

Title: Structure, exchange determinants, and family-wide rab specificity of the tandem helical bundle and Vps9 domains of Rabex-5.

PubMed ID: 15339665

DOI: 10.1016/j.cell.2004.08.009

PubMed ID: 16499958

Title: Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin.

PubMed ID: 16499958

DOI: 10.1016/j.cell.2006.02.020

PubMed ID: 17450153

Title: Structural basis for Rab GTPase activation by VPS9 domain exchange factors.

PubMed ID: 17450153

DOI: 10.1038/nsmb1232

Sequence Information:

  • Length: 491
  • Mass: 56891
  • Checksum: 49ACABA276E65E91
  • Sequence:
    • MSLKSERRGI HVDQSDLLCK KGCGYYGNPA WQGFCSKCWR EEYHKARQKQ IQEDWELAER 
LQREEEEAFA SSQSSQGAQS LTFSKFEEKK TNEKTRKVTT VKKFFSASSR VGSKKEIQEA 
KAPSPSINRQ TSIETDRVSK EFIEFLKTFH KTGQEIYKQT KLFLEGMHYK RDLSIEEQSE 
CAQDFYHNVA ERMQTRGKVP PERVEKIMDQ IEKYIMTRLY KYVFCPETTD DEKKDLAIQK 
RIRALRWVTP QMLCVPVNED IPEVSDMVVK AITDIIEMDS KRVPRDKLAC ITKCSKHIFN 
AIKITKNEPA SADDFLPTLI YIVLKGNPPR LQSNIQYITR FCNPSRLMTG EDGYYFTNLC 
CAVAFIEKLD AQSLNLSQED FDRYMSGQTS PRKQEAESWS PDACLGVKQM YKNLDLLSQL 
NERQERIMNE AKKLEKDLID WTDGIAREVQ DIVEKYPLEI KPPNQPLAAI DSENVENDKL 
PPPLQPQVYA G

Genular Protein ID: 1758576909

Symbol: B3KMF1_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KMF1

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 2 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 RefSeq 3 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 325
  • Mass: 37619
  • Checksum: BA6438AAD976ECD5
  • Sequence:
    • MHYKRDLSIE EQSECAQDFY HNVAERMQTR GKVPPERVEK IMDQIEKYIM TRLYKYVFCP 
ETTDDEKKDL AIQKRIRALR WVTPQMLCVP VNEDIPEVSD MVVKAITDII EMDSKRVPRD 
KLACITKCSK HIFNAIKITK NEPASADDFL PTLIYIVLKG NPPRLQSNIQ YITRFCNPSR 
LMTGEDGYYF TNLCCAVAFI EKLDAQSLNL SQEDFDRYMS GQTSPRKQEA ESWSPDACLG 
VKQMYKNLDL LSQLNERQER IMNEAKKLEK DLIDWTDGIA REVQDIVEKY PLEIKPPNQP 
LAAIDSENVE NDKLPPPLQP QVYAG

Genular Protein ID: 3777355336

Symbol: A8K3R3_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K3R3

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 7 Gene3D 3 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 RefSeq 1 SAM 1 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 491
  • Mass: 56819
  • Checksum: 490689A277DABE91
  • Sequence:
    • MSLKSERRGI HVDQSDLLCK KGCGYYGNPA WQGFCSKCWR EEYHKARQKQ IQEDWELAER 
LQREEEEAFA SSQSSQGAQS LTFSKFEEKK TNEKTRKVTT VKKFFSASSR VGSKKEIQEA 
KAPSPSINRQ TSIETDRVSK EFIEFLKTFH KTGQEIYKQT KLFLEGMHYK RDLSIEEQSE 
CAQDFYHNVA ERMQTRGKVP PERVEKIMDQ IEKYIMTRLY KYVFCPGTTD DEKKDLAIQK 
RIRALRWVTP QMLCVPVNED IPEVSDMVVK AITDIIEMDS KRVPRDKLAC ITKCSKHIFN 
AIKITKNEPA SADDFLPTLI YIVLKGNPPR LQSNIQYITR FCNPSRLMTG EDGYYFTNLC 
CAVAFIEKLD AQSLNLSQED FDRYMSGQTS PRKQEAESWS PDACLGVKQM YKNLDLLSQL 
NERQERIMNE AKKLEKDLID WTDGIAREVQ DIVEKYPLEI KPPNQPLAAI DSENVENDKL 
PPPLQPQVYA G

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.