Details for: GPR35
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 26.0374
Cell Significance Index: -4.0500 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 15.6125
Cell Significance Index: -3.9600 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 10.5106
Cell Significance Index: -4.2700 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 9.8370
Cell Significance Index: -5.0600 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 6.6317
Cell Significance Index: -4.4500 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 3.2929
Cell Significance Index: -4.0600 - Cell Name: precursor cell (CL0011115)
Fold Change: 3.0014
Cell Significance Index: 22.7600 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 2.4828
Cell Significance Index: 71.5400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.8205
Cell Significance Index: 39.4400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.7462
Cell Significance Index: 79.1500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 1.4970
Cell Significance Index: 243.4700 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.1497
Cell Significance Index: 125.0500 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 1.0057
Cell Significance Index: 15.0700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.6814
Cell Significance Index: 47.1300 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 0.6723
Cell Significance Index: 5.5600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.5489
Cell Significance Index: 11.6900 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.4918
Cell Significance Index: 9.0900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.4249
Cell Significance Index: 14.9300 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: 0.4243
Cell Significance Index: 5.9600 - Cell Name: large intestine goblet cell (CL1000320)
Fold Change: 0.3451
Cell Significance Index: 3.7400 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 0.3173
Cell Significance Index: -0.8500 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.3059
Cell Significance Index: 6.3500 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.2592
Cell Significance Index: 6.4800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.2445
Cell Significance Index: 7.8300 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.2137
Cell Significance Index: 3.0600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1914
Cell Significance Index: 18.9300 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: 0.1249
Cell Significance Index: 1.2600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0813
Cell Significance Index: 16.3000 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: 0.0786
Cell Significance Index: 1.0900 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.0758
Cell Significance Index: 2.0300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0646
Cell Significance Index: 12.2900 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.0638
Cell Significance Index: 0.6600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0523
Cell Significance Index: 10.3800 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.0407
Cell Significance Index: 1.0900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0344
Cell Significance Index: 12.3400 - Cell Name: colonocyte (CL1000347)
Fold Change: 0.0210
Cell Significance Index: 0.1300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0189
Cell Significance Index: 1.4500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.0053
Cell Significance Index: 4.8100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0017
Cell Significance Index: 3.2400 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0004
Cell Significance Index: 0.2100 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0010
Cell Significance Index: -1.8000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0016
Cell Significance Index: -2.5200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0021
Cell Significance Index: -0.3700 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0023
Cell Significance Index: -3.1700 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0031
Cell Significance Index: -1.3900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0040
Cell Significance Index: -2.5600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0046
Cell Significance Index: -0.2400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0050
Cell Significance Index: -3.7900 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0057
Cell Significance Index: -4.2200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0057
Cell Significance Index: -4.2100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0069
Cell Significance Index: -0.3100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0073
Cell Significance Index: -4.1000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0075
Cell Significance Index: -3.4200 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0088
Cell Significance Index: -1.1300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0107
Cell Significance Index: -3.0700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0126
Cell Significance Index: -0.8500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0138
Cell Significance Index: -1.7000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0146
Cell Significance Index: -1.7000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0155
Cell Significance Index: -1.5800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0179
Cell Significance Index: -2.4600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0185
Cell Significance Index: -2.6900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0192
Cell Significance Index: -1.2100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0197
Cell Significance Index: -3.3700 - Cell Name: enterocyte (CL0000584)
Fold Change: -0.0201
Cell Significance Index: -0.1300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0215
Cell Significance Index: -4.5200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0227
Cell Significance Index: -0.8600 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.0232
Cell Significance Index: -0.3300 - Cell Name: DN1 thymic pro-T cell (CL0000894)
Fold Change: -0.0251
Cell Significance Index: -0.2600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0260
Cell Significance Index: -2.9800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0272
Cell Significance Index: -0.7600 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0296
Cell Significance Index: -1.5000 - Cell Name: myeloid leukocyte (CL0000766)
Fold Change: -0.0309
Cell Significance Index: -0.2500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0339
Cell Significance Index: -3.5300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0341
Cell Significance Index: -2.2000 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0351
Cell Significance Index: -4.5300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0358
Cell Significance Index: -1.6700 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0379
Cell Significance Index: -2.6800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0410
Cell Significance Index: -4.8400 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0478
Cell Significance Index: -1.9600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0483
Cell Significance Index: -2.2700 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.0485
Cell Significance Index: -1.2400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0534
Cell Significance Index: -3.2800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0540
Cell Significance Index: -3.3100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0614
Cell Significance Index: -4.8600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0635
Cell Significance Index: -4.7300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0638
Cell Significance Index: -1.6400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0662
Cell Significance Index: -3.7200 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0662
Cell Significance Index: -1.8900 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0671
Cell Significance Index: -1.4700 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.0695
Cell Significance Index: -2.0400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0763
Cell Significance Index: -2.4300 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0789
Cell Significance Index: -4.1400 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0800
Cell Significance Index: -2.6200 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0802
Cell Significance Index: -2.8100 - Cell Name: stem cell (CL0000034)
Fold Change: -0.0812
Cell Significance Index: -0.5900 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0826
Cell Significance Index: -4.3000 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0846
Cell Significance Index: -3.6800 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0862
Cell Significance Index: -2.1500 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0919
Cell Significance Index: -1.9500 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.0998
Cell Significance Index: -2.0900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3627639304
Symbol: GPR35_HUMAN
Name: G-protein coupled receptor 35
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9479505
Title: Discovery of three novel G-protein-coupled receptor genes.
PubMed ID: 9479505
PubMed ID: 11017071
Title: Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus.
PubMed ID: 11017071
DOI: 10.1038/79876
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 16754668
Title: Kynurenic acid as a ligand for orphan G protein-coupled receptor GPR35.
PubMed ID: 16754668
PubMed ID: 20361937
Title: GPR35 is a novel lysophosphatidic acid receptor.
PubMed ID: 20361937
PubMed ID: 35148838
Title: GPR35 promotes neutrophil recruitment in response to serotonin metabolite 5-HIAA.
PubMed ID: 35148838
PubMed ID: 35101446
Title: Agonist-induced phosphorylation of orthologues of the orphan receptor GPR35 functions as an activation sensor.
PubMed ID: 35101446
PubMed ID: 37660910
Title: G protein-receptor kinases 5/6 are the key regulators of G protein-coupled receptor 35-arrestin interactions.
PubMed ID: 37660910
PubMed ID: 36543774
Title: Insights into divalent cation regulation and G13-coupling of orphan receptor GPR35.
PubMed ID: 36543774
Sequence Information:
- Length: 309
- Mass: 34072
- Checksum: 97734FB7231B26F0
- Sequence:
MNGTYNTCGS SDLTWPPAIK LGFYAYLGVL LVLGLLLNSL ALWVFCCRMQ QWTETRIYMT NLAVADLCLL CTLPFVLHSL RDTSDTPLCQ LSQGIYLTNR YMSISLVTAI AVDRYVAVRH PLRARGLRSP RQAAAVCAVL WVLVIGSLVA RWLLGIQEGG FCFRSTRHNF NSMAFPLLGF YLPLAVVVFC SLKVVTALAQ RPPTDVGQAE ATRKAARMVW ANLLVFVVCF LPLHVGLTVR LAVGWNACAL LETIRRALYI TSKLSDANCC LDAICYYYMA KEFQEASALA VAPSAKAHKS QDSLCVTLA
Genular Protein ID: 3993932683
Symbol: A8K2J1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 340
- Mass: 37463
- Checksum: 4EF3FC3F3AEAB714
- Sequence:
MLSGSRAVPT PHHGSEELLK YMLHSPCVSL TMNGTYNTCG SSDLTWPPAI KLGFYAYLGV LLVLGLLLNS LALWVFCCRM QQWTETRIYM TNLAVADLCL LCTLPFVLHS LRDTSDTPLC QLSQGIYLTN RYMSISLVMA IAVDRYVAVR HPLRARGLRS PRQAAAVCAV LWVLVIGSLV ARWLLGIQEG GFCFRSTRHN FNSMAFPLLG FYLPLAVVVF CSLKVVTALA QRPPTDVGQA EATRKAARMV WANLLVFVVC FLPLHVGLTV RLAVGWNACA LLETIRRALY ITSKLSDANC CLDAICYYYM AKEFQEASAL AVAPSAKAHK SQDSLCVTLA
Genular Protein ID: 2306372971
Symbol: B2RA17_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 309
- Mass: 34056
- Checksum: 33335EF23BDFF371
- Sequence:
MNGTYNTCGS SDLTWPPAIK LGFYAYLGVL LVLGLLLNSL ALWVFCCRMQ QWTETRIYMT NLAVADLCLL CTLPFVLHSL RDTSDTPLCQ LSQGIYLTNR YMSISLVTAI AVDRYVAVRH PLRARGLRSP RQAAAVCAVL WVLVIGSLVA RWPLGIQEGG FCFRSTRHNF NSMAFPLLGF YLPLAVVVFC SLKVVTALAQ RPPTDVGQAE ATRKAARMVW ANLLVFVVCF LPLHVGLTVR LAVGWNACAL LETIRRALYI TSKLSDANCC LDAICYYYMA KEFQEASALA VAPSAKAHKS QDSLCVTLA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.