Details for: ANK2

Gene ID: 287

Symbol: ANK2

Ensembl ID: ENSG00000145362

Description: ankyrin 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 401.6530
    Cell Significance Index: -165.4600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 302.4108
    Cell Significance Index: -142.7800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 29.4893
    Cell Significance Index: -64.5400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 8.2185
    Cell Significance Index: 197.1000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 7.6427
    Cell Significance Index: 469.7600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 6.4472
    Cell Significance Index: 2312.5000
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 6.4348
    Cell Significance Index: 67.0300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 6.0434
    Cell Significance Index: 463.7700
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 5.4671
    Cell Significance Index: 42.1400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 5.2115
    Cell Significance Index: 350.4200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 4.8623
    Cell Significance Index: 6611.4100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 4.2802
    Cell Significance Index: 269.7700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 4.1613
    Cell Significance Index: 2878.1200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 3.8368
    Cell Significance Index: 169.7100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 3.8305
    Cell Significance Index: 145.0500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 3.7373
    Cell Significance Index: 749.6900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 3.7063
    Cell Significance Index: 81.1600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 3.5655
    Cell Significance Index: 200.0800
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 3.5435
    Cell Significance Index: 49.5500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 3.1889
    Cell Significance Index: 91.0000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.8614
    Cell Significance Index: 36.3300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.3381
    Cell Significance Index: 2060.0200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 1.1116
    Cell Significance Index: 19.0500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.0477
    Cell Significance Index: 665.4300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.9691
    Cell Significance Index: 24.9100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.8282
    Cell Significance Index: 1527.4800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.8074
    Cell Significance Index: 36.6000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.6993
    Cell Significance Index: 1316.7200
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: 0.6632
    Cell Significance Index: 8.2700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5711
    Cell Significance Index: 515.6700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2813
    Cell Significance Index: 53.5300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.2802
    Cell Significance Index: 127.1700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.1775
    Cell Significance Index: 2.6200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0162
    Cell Significance Index: 0.5700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0456
    Cell Significance Index: -9.0500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0506
    Cell Significance Index: -37.0800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0654
    Cell Significance Index: -4.0100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.1569
    Cell Significance Index: -15.5200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.1774
    Cell Significance Index: -131.4400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.2112
    Cell Significance Index: -115.3300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.2320
    Cell Significance Index: -175.6000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.2402
    Cell Significance Index: -39.0700
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.2414
    Cell Significance Index: -2.6300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.2689
    Cell Significance Index: -151.6700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2729
    Cell Significance Index: -39.6700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.2927
    Cell Significance Index: -182.8000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.3079
    Cell Significance Index: -3.6700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.3203
    Cell Significance Index: -141.6200
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.4025
    Cell Significance Index: -5.0800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.4388
    Cell Significance Index: -126.2500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.5324
    Cell Significance Index: -15.3400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.5453
    Cell Significance Index: -17.4700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.5982
    Cell Significance Index: -107.8400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.6673
    Cell Significance Index: -72.5900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.7343
    Cell Significance Index: -100.8500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.7943
    Cell Significance Index: -167.3100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.8261
    Cell Significance Index: -86.0100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.8540
    Cell Significance Index: -18.2600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.9797
    Cell Significance Index: -167.2900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.9846
    Cell Significance Index: -121.0600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.0660
    Cell Significance Index: -55.9700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -1.0774
    Cell Significance Index: -139.1900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -1.1836
    Cell Significance Index: -151.7300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -1.2323
    Cell Significance Index: -145.3300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -1.3511
    Cell Significance Index: -157.4600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -1.3559
    Cell Significance Index: -138.5100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -1.3804
    Cell Significance Index: -95.4700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -1.4221
    Cell Significance Index: -28.1200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -1.4837
    Cell Significance Index: -169.9800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.5884
    Cell Significance Index: -125.8000
  • Cell Name: neural cell (CL0002319)
    Fold Change: -1.6342
    Cell Significance Index: -19.0700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.6426
    Cell Significance Index: -53.7800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -1.6482
    Cell Significance Index: -98.9500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.7809
    Cell Significance Index: -56.7200
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -1.8198
    Cell Significance Index: -23.6000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -1.8695
    Cell Significance Index: -139.3300
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -1.8790
    Cell Significance Index: -15.5100
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -1.8936
    Cell Significance Index: -25.2600
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -1.9398
    Cell Significance Index: -41.1700
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -1.9563
    Cell Significance Index: -25.0900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -2.0457
    Cell Significance Index: -144.6800
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -2.1822
    Cell Significance Index: -43.8100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -2.2771
    Cell Significance Index: -146.9100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -2.3034
    Cell Significance Index: -119.9800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -2.3609
    Cell Significance Index: -65.9800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -2.4219
    Cell Significance Index: -125.8100
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -2.4268
    Cell Significance Index: -41.9600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -2.6453
    Cell Significance Index: -92.6700
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -2.6828
    Cell Significance Index: -32.5200
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -2.6887
    Cell Significance Index: -85.0400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -2.7007
    Cell Significance Index: -58.5100
  • Cell Name: neuron (CL0000540)
    Fold Change: -2.7618
    Cell Significance Index: -26.1800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -2.7904
    Cell Significance Index: -39.9600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -2.8290
    Cell Significance Index: -132.9600
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -2.9137
    Cell Significance Index: -126.7000
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -3.0070
    Cell Significance Index: -37.9500
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -3.0181
    Cell Significance Index: -32.3600
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -3.0779
    Cell Significance Index: -66.5000
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -3.0933
    Cell Significance Index: -77.1600
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -3.1237
    Cell Significance Index: -22.7100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** ANK2 is a cytoskeletal protein that exhibits the following key characteristics: 1. **Cytoskeletal binding**: ANK2 binds to spectrin and actin filaments, linking them to the plasma membrane and contributing to the organization of the sarcomere. 2. **Plasma membrane attachment**: ANK2 is anchored to the plasma membrane through its interaction with spectrin, ensuring the structural integrity of cardiac muscle cells. 3. **Spectrin binding**: ANK2 interacts with spectrin, a cytoskeletal protein that provides mechanical stability to the plasma membrane. 4. **Actin filament binding**: ANK2 also interacts with actin filaments, contributing to the organization of the sarcomere and maintaining the structural integrity of cardiac muscle cells. 5. **Neuronal and glial expression**: ANK2 is expressed in neurons and glial cells, highlighting its role in maintaining the structural integrity of the nervous system. **Pathways and Functions** ANK2 is involved in various cellular pathways and functions, including: 1. **Cardiac muscle contraction**: ANK2 regulates cardiac muscle contraction by maintaining the structural integrity of the sarcomere and regulating calcium ion transmembrane transporter activity. 2. **Calcium ion homeostasis**: ANK2 contributes to the regulation of intracellular calcium ion homeostasis, which is essential for cardiac muscle contraction and relaxation. 3. **Neuronal development and function**: ANK2 is involved in the development and maintenance of neuronal function, particularly in the regulation of synaptic transmission and neuronal plasticity. 4. **Cardiac conduction**: ANK2 regulates cardiac conduction by maintaining the structural integrity of the cardiac muscle cell membrane and regulating the release of sequestered calcium ions. 5. **Sarcolemma organization**: ANK2 contributes to the organization of the sarcolemma, the plasma membrane of cardiac muscle cells, and regulates the structural integrity of the cardiac muscle cell membrane. **Clinical Significance** ANK2 dysregulation has been implicated in various cardiac and neurological disorders, including: 1. **Arrhythmias**: ANK2 mutations have been associated with arrhythmias, including atrial fibrillation and ventricular tachycardia. 2. **Cardiac muscle disease**: ANK2 dysregulation has been implicated in cardiac muscle diseases, including dilated cardiomyopathy and hypertrophic cardiomyopathy. 3. **Neurological disorders**: ANK2 mutations have been associated with neurological disorders, including epilepsy and autism spectrum disorder. 4. **Methylmercury toxicity**: ANK2 has been shown to be sensitive to methylmercury toxicity, highlighting the importance of ANK2 in maintaining cellular homeostasis in response to environmental toxins. In conclusion, ANK2 is a critical protein that plays a pivotal role in maintaining the structural integrity and function of cardiac muscle cells and neurons. Its dysregulation has been implicated in various cardiac and neurological disorders, highlighting the importance of ANK2 in maintaining cellular homeostasis and regulating cardiac and nervous system function.

Genular Protein ID: 3179259623

Symbol: ANK2_HUMAN

Name: Ankyrin-2

UniProtKB Accession Codes:

Q01484 Q01485 Q08AC7 Q08AC8 Q7Z3L5

Database IDs:

ABCD 1 AGR 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 11 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 68 Gene3D 4 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 10 PDBsum 10 PIR 1 PRINTS 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 6 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 2 RefSeq 3 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1830053

Title: Isolation and characterization of cDNAs encoding human brain ankyrins reveal a family of alternatively spliced genes.

PubMed ID: 1830053

DOI: 10.1083/jcb.114.2.241

PubMed ID: 8253844

Title: 440-kD ankyrinB: structure of the major developmentally regulated domain and selective localization in unmyelinated axons.

PubMed ID: 8253844

DOI: 10.1083/jcb.123.6.1463

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1833308

Title: Isolation and chromosomal localization of a novel nonerythroid ankyrin gene.

PubMed ID: 1833308

DOI: 10.1016/0888-7543(91)90173-c

PubMed ID: 12571597

Title: Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death.

PubMed ID: 12571597

DOI: 10.1038/nature01335

PubMed ID: 15262991

Title: Ankyrin-B targets beta2-spectrin to an intracellular compartment in neonatal cardiomyocytes.

PubMed ID: 15262991

DOI: 10.1074/jbc.m406018200

PubMed ID: 15611082

Title: The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.

PubMed ID: 15611082

DOI: 10.1074/jbc.m413351200

PubMed ID: 19007774

Title: Ankyrin-B is required for coordinated expression of beta-2-spectrin, the Na/K-ATPase and the Na/Ca exchanger in the inner segment of rod photoreceptors.

PubMed ID: 19007774

DOI: 10.1016/j.exer.2008.09.022

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 27718357

Title: Ankyrin-B is a PI3P effector that promotes polarized alpha5beta1-integrin recycling via recruiting RabGAP1L to early endosomes.

PubMed ID: 27718357

DOI: 10.7554/elife.20417

PubMed ID: 22411828

Title: Structure of the ZU5-ZU5-UPA-DD tandem of ankyrin-B reveals interaction surfaces necessary for ankyrin function.

PubMed ID: 22411828

DOI: 10.1073/pnas.1200613109

PubMed ID: 15178757

Title: A cardiac arrhythmia syndrome caused by loss of ankyrin-B function.

PubMed ID: 15178757

DOI: 10.1073/pnas.0402546101

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 17940615

Title: Ankyrin-B syndrome: enhanced cardiac function balanced by risk of cardiac death and premature senescence.

PubMed ID: 17940615

DOI: 10.1371/journal.pone.0001051

Sequence Information:

  • Length: 3957
  • Mass: 433715
  • Checksum: 41C1A240CC5A3B72
  • Sequence:
    • MMNEDAAQKS DSGEKFNGSS QRRKRPKKSD SNASFLRAAR AGNLDKVVEY LKGGIDINTC 
NQNGLNALHL AAKEGHVGLV QELLGRGSSV DSATKKGNTA LHIASLAGQA EVVKVLVKEG 
ANINAQSQNG FTPLYMAAQE NHIDVVKYLL ENGANQSTAT EDGFTPLAVA LQQGHNQAVA 
ILLENDTKGK VRLPALHIAA RKDDTKSAAL LLQNDHNADV QSKMMVNRTT ESGFTPLHIA 
AHYGNVNVAT LLLNRGAAVD FTARNGITPL HVASKRGNTN MVKLLLDRGG QIDAKTRDGL 
TPLHCAARSG HDQVVELLLE RGAPLLARTK NGLSPLHMAA QGDHVECVKH LLQHKAPVDD 
VTLDYLTALH VAAHCGHYRV TKLLLDKRAN PNARALNGFT PLHIACKKNR IKVMELLVKY 
GASIQAITES GLTPIHVAAF MGHLNIVLLL LQNGASPDVT NIRGETALHM AARAGQVEVV 
RCLLRNGALV DARAREEQTP LHIASRLGKT EIVQLLLQHM AHPDAATTNG YTPLHISARE 
GQVDVASVLL EAGAAHSLAT KKGFTPLHVA AKYGSLDVAK LLLQRRAAAD SAGKNGLTPL 
HVAAHYDNQK VALLLLEKGA SPHATAKNGY TPLHIAAKKN QMQIASTLLN YGAETNIVTK 
QGVTPLHLAS QEGHTDMVTL LLDKGANIHM STKSGLTSLH LAAQEDKVNV ADILTKHGAD 
QDAHTKLGYT PLIVACHYGN VKMVNFLLKQ GANVNAKTKN GYTPLHQAAQ QGHTHIINVL 
LQHGAKPNAT TANGNTALAI AKRLGYISVV DTLKVVTEEV TTTTTTITEK HKLNVPETMT 
EVLDVSDEEG DDTMTGDGGE YLRPEDLKEL GDDSLPSSQF LDGMNYLRYS LEGGRSDSLR 
SFSSDRSHTL SHASYLRDSA VMDDSVVIPS HQVSTLAKEA ERNSYRLSWG TENLDNVALS 
SSPIHSGFLV SFMVDARGGA MRGCRHNGLR IIIPPRKCTA PTRVTCRLVK RHRLATMPPM 
VEGEGLASRL IEVGPSGAQF LGKLHLPTAP PPLNEGESLV SRILQLGPPG TKFLGPVIVE 
IPHFAALRGK ERELVVLRSE NGDSWKEHFC DYTEDELNEI LNGMDEVLDS PEDLEKKRIC 
RIITRDFPQY FAVVSRIKQD SNLIGPEGGV LSSTVVPQVQ AVFPEGALTK RIRVGLQAQP 
MHSELVKKIL GNKATFSPIV TLEPRRRKFH KPITMTIPVP KASSDVMLNG FGGDAPTLRL 
LCSITGGTTP AQWEDITGTT PLTFVNECVS FTTNVSARFW LIDCRQIQES VTFASQVYRE 
IICVPYMAKF VVFAKSHDPI EARLRCFCMT DDKVDKTLEQ QENFAEVARS RDVEVLEGKP 
IYVDCFGNLV PLTKSGQHHI FSFFAFKENR LPLFVKVRDT TQEPCGRLSF MKEPKSTRGL 
VHQAICNLNI TLPIYTKESE SDQEQEEEID MTSEKNDETE STETSVLKSH LVNEVPVLAS 
PDLLSEVSEM KQDLIKMTAI LTTDVSDKAG SIKVKELVKA AEEEPGEPFE IVERVKEDLE 
KVNEILRSGT CTRDESSVQS SRSERGLVEE EWVIVSDEEI EEARQKAPLE ITEYPCVEVR 
IDKEIKGKVE KDSTGLVNYL TDDLNTCVPL PKEQLQTVQD KAGKKCEALA VGRSSEKEGK 
DIPPDETQST QKQHKPSLGI KKPVRRKLKE KQKQKEEGLQ ASAEKAELKK GSSEESLGED 
PGLAPEPLPT VKATSPLIEE TPIGSIKDKV KALQKRVEDE QKGRSKLPIR VKGKEDVPKK 
TTHRPHPAAS PSLKSERHAP GSPSPKTERH STLSSSAKTE RHPPVSPSSK TEKHSPVSPS 
AKTERHSPAS SSSKTEKHSP VSPSTKTERH SPVSSTKTER HPPVSPSGKT DKRPPVSPSG 
RTEKHPPVSP GRTEKRLPVS PSGRTDKHQP VSTAGKTEKH LPVSPSGKTE KQPPVSPTSK 
TERIEETMSV RELMKAFQSG QDPSKHKTGL FEHKSAKQKQ PQEKGKVRVE KEKGPILTQR 
EAQKTENQTI KRGQRLPVTG TAESKRGVRV SSIGVKKEDA AGGKEKVLSH KIPEPVQSVP 
EEESHRESEV PKEKMADEQG DMDLQISPDR KTSTDFSEVI KQELEDNDKY QQFRLSEETE 
KAQLHLDQVL TSPFNTTFPL DYMKDEFLPA LSLQSGALDG SSESLKNEGV AGSPCGSLME 
GTPQISSEES YKHEGLAETP ETSPESLSFS PKKSEEQTGE TKESTKTETT TEIRSEKEHP 
TTKDITGGSE ERGATVTEDS ETSTESFQKE ATLGSPKDTS PKRQDDCTGS CSVALAKETP 
TGLTEEAACD EGQRTFGSSA HKTQTDSEVQ ESTATSDETK ALPLPEASVK TDTGTESKPQ 
GVIRSPQGLE LALPSRDSEV LSAVADDSLA VSHKDSLEAS PVLEDNSSHK TPDSLEPSPL 
KESPCRDSLE SSPVEPKMKA GIFPSHFPLP AAVAKTELLT EVASVRSRLL RDPDGSAEDD 
SLEQTSLMES SGKSPLSPDT PSSEEVSYEV TPKTTDVSTP KPAVIHECAE EDDSENGEKK 
RFTPEEEMFK MVTKIKMFDE LEQEAKQKRD YKKEPKQEES SSSSDPDADC SVDVDEPKHT 
GSGEDESGVP VLVTSESRKV SSSSESEPEL AQLKKGADSG LLPEPVIRVQ PPSPLPSSMD 
SNSSPEEVQF QPVVSKQYTF KMNEDTQEEP GKSEEEKDSE SHLAEDRHAV STEAEDRSYD 
KLNRDTDQPK ICDGHGCEAM SPSSSAAPVS SGLQSPTGDD VDEQPVIYKE SLALQGTHEK 
DTEGEELDVS RAESPQADCP SESFSSSSSL PHCLVSEGKE LDEDISATSS IQKTEVTKTD 
ETFENLPKDC PSQDSSITTQ TDRFSMDVPV SDLAENDEIY DPQITSPYEN VPSQSFFSSE 
ESKTQTDANH TTSFHSSEVY SVTITSPVED VVVASSSSGT VLSKESNFEG QDIKMESQQE 
STLWEMQSDS VSSSFEPTMS ATTTVVGEQI SKVIITKTDV DSDSWSEIRE DDEAFEARVK 
EEEQKIFGLM VDRQSQGTTP DTTPARTPTE EGTPTSEQNP FLFQEGKLFE MTRSGAIDMT 
KRSYADESFH FFQIGQESRE ETLSEDVKEG ATGADPLPLE TSAESLALSE SKETVDDEAD 
LLPDDVSEEV EEIPASDAQL NSQMGISAST ETPTKEAVSV GTKDLPTVQT GDIPPLSGVK 
QISCPDSSEP AVQVQLDFST LTRSVYSDRG DDSPDSSPEE QKSVIEIPTA PMENVPFTES 
KSKIPVRTMP TSTPAPPSAE YESSVSEDFL SSVDEENKAD EAKPKSKLPV KVPLQRVEQQ 
LSDLDTSVQK TVAPQGQDMA SIAPDNRSKS ESDASSLDSK TKCPVKTRSY TETETESRER 
AEELELESEE GATRPKILTS RLPVKSRSTT SSCRGGTSPT KESKEHFFDL YRNSIEFFEE 
ISDEASKLVD RLTQSEREQE IVSDDESSSA LEVSVIENLP PVETEHSVPE DIFDTRPIWD 
ESIETLIERI PDENGHDHAE DPQDEQERIE ERLAYIADHL GFSWTELARE LDFTEEQIHQ 
IRIENPNSLQ DQSHALLKYW LERDGKHATD TNLVECLTKI NRMDIVHLME TNTEPLQERI 
SHSYAEIEQT ITLDHSEGFS VLQEELCTAQ HKQKEEQAVS KESETCDHPP IVSEEDISVG 
YSTFQDGVPK TEGDSSATAL FPQTHKEQVQ QDFSGKMQDL PEESSLEYQQ EYFVTTPGTE 
TSETQKAMIV PSSPSKTPEE VSTPAEEEKL YLQTPTSSER GGSPIIQEPE EPSEHREESS 
PRKTSLVIVE SADNQPETCE RLDEDAAFEK GDDMPEIPPE TVTEEEYIDE HGHTVVKKVT 
RKIIRRYVSS EGTEKEEIMV QGMPQEPVNI EEGDGYSKVI KRVVLKSDTE QSEDNNE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.