Details for: GRIK1

Gene ID: 2897

Symbol: GRIK1

Ensembl ID: ENSG00000171189

Description: glutamate ionotropic receptor kainate type subunit 1

Associated with

  • Activation of ca-permeable kainate receptor
    (R-HSA-451308)
  • Activation of kainate receptors upon glutamate binding
    (R-HSA-451326)
  • Activation of na-permeable kainate receptors
    (R-HSA-451307)
  • Ionotropic activity of kainate receptors
    (R-HSA-451306)
  • Neuronal system
    (R-HSA-112316)
  • Neurotransmitter receptors and postsynaptic signal transmission
    (R-HSA-112314)
  • Transmission across chemical synapses
    (R-HSA-112315)
  • Central nervous system development
    (GO:0007417)
  • Chemical synaptic transmission
    (GO:0007268)
  • Glutamate receptor signaling pathway
    (GO:0007215)
  • Intracellular membrane-bounded organelle
    (GO:0043231)
  • Ionotropic glutamate receptor signaling pathway
    (GO:0035235)
  • Kainate selective glutamate receptor activity
    (GO:0015277)
  • Kainate selective glutamate receptor complex
    (GO:0032983)
  • Modulation of chemical synaptic transmission
    (GO:0050804)
  • Monoatomic ion transmembrane transport
    (GO:0034220)
  • Nervous system development
    (GO:0007399)
  • Plasma membrane
    (GO:0005886)
  • Postsynaptic density membrane
    (GO:0098839)
  • Presynaptic membrane
    (GO:0042734)
  • Regulation of postsynaptic membrane potential
    (GO:0060078)
  • Regulation of synaptic transmission, glutamatergic
    (GO:0051966)
  • Synaptic transmission, glutamatergic
    (GO:0035249)
  • Transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
    (GO:1904315)

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 7.44
    Marker Score: 251428
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 3.78
    Marker Score: 12663
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 3.66
    Marker Score: 9165
  • Cell Name: bipolar neuron (CL0000103)
    Fold Change: 3.33
    Marker Score: 1118
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 3.19
    Marker Score: 1430
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: 2.99
    Marker Score: 902
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.91
    Marker Score: 57834
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 2.86
    Marker Score: 13228
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.84
    Marker Score: 42517
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.8
    Marker Score: 21483
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 2.78
    Marker Score: 1335.5
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 2.43
    Marker Score: 1826
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.33
    Marker Score: 9676
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 2.32
    Marker Score: 2869
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.22
    Marker Score: 8569
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 2.04
    Marker Score: 4678
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.03
    Marker Score: 74853
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 2.01
    Marker Score: 1128
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.85
    Marker Score: 70226
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 1.82
    Marker Score: 7584
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 1.62
    Marker Score: 8683
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.61
    Marker Score: 1168
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.58
    Marker Score: 1573
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.54
    Marker Score: 15918
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.52
    Marker Score: 2556
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.48
    Marker Score: 3005
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.46
    Marker Score: 167533
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 1.39
    Marker Score: 501
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.37
    Marker Score: 868
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.3
    Marker Score: 2014
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.29
    Marker Score: 5252
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.26
    Marker Score: 853
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 1.25
    Marker Score: 7507
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.24
    Marker Score: 746
  • Cell Name: monocyte (CL0000576)
    Fold Change: 1.18
    Marker Score: 1539
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 1.17
    Marker Score: 487
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.14
    Marker Score: 4802
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.1
    Marker Score: 406.5
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.09
    Marker Score: 502
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 1.09
    Marker Score: 633
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.09
    Marker Score: 2389
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.07
    Marker Score: 449
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.07
    Marker Score: 2510
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.05
    Marker Score: 16430
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: 1.01
    Marker Score: 519
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71800
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48025
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.99
    Marker Score: 508
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30406
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.98
    Marker Score: 462
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.96
    Marker Score: 855
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2412
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 0.94
    Marker Score: 256
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.93
    Marker Score: 5318
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.93
    Marker Score: 373
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 0.92
    Marker Score: 8642
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2739
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.91
    Marker Score: 533
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.91
    Marker Score: 326
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.9
    Marker Score: 344.5
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.89
    Marker Score: 288
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.88
    Marker Score: 223
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5282
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.87
    Marker Score: 664.5
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.84
    Marker Score: 491
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 0.79
    Marker Score: 1430
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.78
    Marker Score: 328
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1263
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.78
    Marker Score: 708
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.76
    Marker Score: 396
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 0.76
    Marker Score: 754
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 0.73
    Marker Score: 395
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.72
    Marker Score: 462
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 0.71
    Marker Score: 813
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.7
    Marker Score: 180
  • Cell Name: goblet cell (CL0000160)
    Fold Change: 0.7
    Marker Score: 4668
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.7
    Marker Score: 2934
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.7
    Marker Score: 332
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.69
    Marker Score: 454
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.66
    Marker Score: 171
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.66
    Marker Score: 1876
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 0.65
    Marker Score: 1563
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 0.64
    Marker Score: 2275
  • Cell Name: sympathetic neuron (CL0011103)
    Fold Change: 0.64
    Marker Score: 211
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.62
    Marker Score: 373
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 0.62
    Marker Score: 13216
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 0.61
    Marker Score: 404
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 0.61
    Marker Score: 422
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 0.61
    Marker Score: 13542
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.6
    Marker Score: 304
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.6
    Marker Score: 189
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.59
    Marker Score: 474
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.59
    Marker Score: 186.5
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.59
    Marker Score: 184
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 0.58
    Marker Score: 1566
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.57
    Marker Score: 285
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.57
    Marker Score: 150
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.56
    Marker Score: 295
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.55
    Marker Score: 1047
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 0.55
    Marker Score: 143

Hover over a box to see details here...

Hover over a box to see details here...

Hover over a box to see details here...

Other Information

**Key characteristics:** * GRIK1 is a transmembrane protein with a predicted molecular weight of approximately 140 kDa. * It is a member of the glutamate receptor superfamily, which is a large family of ionotropic glutamate receptors that are expressed in various brain regions. * GRIK1 is a calcium-permeable channel, meaning that it opens when calcium ions bind to its cytoplasmic domain. * It is a ligand-gated channel, meaning that its opening is regulated by the binding of a specific ligand, glutamate. **Pathways and functions:** * GRIK1 is a key component of the ionotropic glutamate receptor signaling pathway, which is responsible for regulating synaptic transmission in the brain. * The pathway is activated by the binding of glutamate to its ligand-gated channel. * This activation triggers the opening of the channel, which allows calcium ions to flow into the cell. * Calcium ions binding to GRIK1-coupled receptors cause a conformational change in the protein, which exposes a binding site on the cytoplasmic domain of the channel. * This binding site is then bound by an intracellular signaling molecule, which initiates a cascade of intracellular events that ultimately lead to a change in synaptic transmission. **Clinical significance:** * Mutations in GRIK1 have been linked to several neurological disorders, including epilepsy, schizophrenia, and autism. * These mutations can lead to the loss of GRIK1 function, which can result in abnormal synaptic transmission and neuronal activity. * Understanding the role of GRIK1 in the brain can provide insights into the development of new therapeutic strategies for neurological disorders. **Additional notes:** * GRIK1 is a relatively conserved protein, with similar sequences found in mammals, birds, and reptiles. * It is expressed in a variety of brain regions, including the cerebral cortex, hippocampus, thalamus, and basal ganglia. * GRIK1 is a highly important protein for synaptic transmission, and its dysfunction can have a significant impact on neuronal function.

Genular Protein ID: 3048166168

Symbol: GRIK1_HUMAN

Name: Glutamate receptor ionotropic, kainate 1

UniProtKB Accession Codes:

P39086 Q13001 Q86SU9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 4 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 4 DrugCentral 1 EMBL 3 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 14 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 12 PDBsum 11 PIR 1 PRINTS 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 2 RefSeq 4 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 8260617

Title: Expression and novel subunit isoforms of glutamate receptor genes GluR5 and GluR6.

PubMed ID: 8260617

DOI: 10.1097/00001756-199309150-00014

PubMed ID: 8589992

Title: cDNA cloning and functional properties of human glutamate receptor EAA3 (GluR5) in homomeric and heteromeric configuration.

PubMed ID: 8589992

PubMed ID: 7696618

Title: RNA editing of human kainate receptor subunits.

PubMed ID: 7696618

DOI: 10.1097/00001756-199412000-00055

PubMed ID: 11702055

Title: Association study of polymorphisms in the GluR5 kainate receptor gene (GRIK1) with schizophrenia.

PubMed ID: 11702055

DOI: 10.1097/00041444-200109000-00005

Sequence Information:

  • Length: 918
  • Mass: 103981
  • Checksum: 0EB8DB6356599002
  • Sequence:
    • MEHGTLLAQP GLWTRDTSWA LLYFLCYILP QTAPQVLRIG GIFETVENEP VNVEELAFKF 
AVTSINRNRT LMPNTTLTYD IQRINLFDSF EASRRACDQL ALGVAALFGP SHSSSVSAVQ 
SICNALEVPH IQTRWKHPSV DNKDLFYINL YPDYAAISRA ILDLVLYYNW KTVTVVYEDS 
TGLIRLQELI KAPSRYNIKI KIRQLPSGNK DAKPLLKEMK KGKEFYVIFD CSHETAAEIL 
KQILFMGMMT EYYHYFFTTL DLFALDLELY RYSGVNMTGF RLLNIDNPHV SSIIEKWSME 
RLQAPPRPET GLLDGMMTTE AALMYDAVYM VAIASHRASQ LTVSSLQCHR HKPWRLGPRF 
MNLIKEARWD GLTGHITFNK TNGLRKDFDL DIISLKEEGT EKAAGEVSKH LYKVWKKIGI 
WNSNSGLNMT DSNKDKSSNI TDSLANRTLI VTTILEEPYV MYRKSDKPLY GNDRFEGYCL 
DLLKELSNIL GFIYDVKLVP DGKYGAQNDK GEWNGMVKEL IDHRADLAVA PLTITYVREK 
VIDFSKPFMT LGISILYRKP NGTNPGVFSF LNPLSPDIWM YVLLACLGVS CVLFVIARFT 
PYEWYNPHPC NPDSDVVENN FTLLNSFWFG VGALMQQGSE LMPKALSTRI VGGIWWFFTL 
IIISSYTANL AAFLTVERME SPIDSADDLA KQTKIEYGAV RDGSTMTFFK KSKISTYEKM 
WAFMSSRQQT ALVRNSDEGI QRVLTTDYAL LMESTSIEYV TQRNCNLTQI GGLIDSKGYG 
VGTPIGSPYR DKITIAILQL QEEGKLHMMK EKWWRGNGCP EEDNKEASAL GVENIGGIFI 
VLAAGLVLSV FVAIGEFIYK SRKNNDIEQA FCFFYGLQCK QTHPTNSTSG TTLSTDLECG 
KLIREERGIR KQSSVHTV

Genular Protein ID: 621427626

Symbol: B7Z256_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z256

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 4 Gene3D 3 GenomeRNAi 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 1 Pfam 3 RefSeq 1 RuleBase 1 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 748
  • Mass: 84380
  • Checksum: 5968D061F7B81698
  • Sequence:
    • MEHGTLLAQP GLWTRDTSWA LLYFLCYILP QTAPQVLRIA CDQLALGVAA LFGPSHSSSV 
SAVQSICNAL EVPHIQTRWK HPSVDNKDLF YINLYPDYAA ISRAILDLVL YYNWKTVTVV 
YEDSTGLIRL QELIKAPSRY NIKIKIRQLP SGNKDAKPLL KEMKKGKEFY VIFDCSHETA 
AEILKQILFM GMMTEYYHYF FTTLDLFALD LELYRYSGVN MTGFRLLNID NPHVSSIIEK 
WSMERLQAPP RPETGLLDGM MTTEAALMYD AVYMVAIASH RASQLTVSSL QCHRHKPWRL 
GPRFMNLIKE ARWDGLTGHI TFNKTNGLRK DFDLDIISLK EEGTEKIGIW NSNSGLNMTD 
SNKDKSSNIT DSLANRTLIV TTILRADLAV APLTITYVRE KVIDFSKPFM TLGISILYRK 
PNGTNPGVFS FLNPLSPDIW MYVLLACLGV SCVLFVIARF TPYEWYNPHP CNPDSDVVEN 
NFTLLNSFWF GVGALMRQGS ELMPKALSTR IVGGIWWFFT LIIISSYTAN LAAFLTVERM 
ESPIDSADDL AKQTKIEYGA VRDGSTMTFF KKSKISTYEK MWAFMSSRQQ TAPVRNSDEG 
IQRVLTTDYA LLMESTSIEY VTQRNCNLTQ IGGLIDSKGY GVGTPIGSPY RDKITIAILQ 
LQEEGKLHMM KEKWWRGNGC PEEGNKEASA LGVENIGGIF IVLAAGLVLS VFVAIGEFIY 
KSRKNNDIEQ CLSFNAIMEE LGISLKNQ

Genular Protein ID: 1499476569

Symbol: E7EPY9_HUMAN

Name: N/A

UniProtKB Accession Codes:

E7EPY9

Database IDs:

ARBA 12 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 7 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 3 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 6 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 2 RefSeq 1 RuleBase 1 SMART 4 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

Sequence Information:

  • Length: 934
  • Mass: 106151
  • Checksum: 603CAEE6E9EEBD10
  • Sequence:
    • MEHGTLLAQP GLWTRDTSWA LLYFLCYILP QTAPQVLRIG GIFETVENEP VNVEELAFKF 
AVTSINRNRT LMPNTTLTYD IQRINLFDSF EASRRACDQL ALGVAALFGP SHSSSVSAVQ 
SICNALEVPH IQTRWKHPSV DNKDLFYINL YPDYAAISRA ILDLVLYYNW KTVTVVYEDS 
TGLIRLQELI KAPSRYNIKI KIRQLPSGNK DAKPLLKEMK KGKEFYVIFD CSHETAAEIL 
KQILFMGMMT EYYHYFFTTL DLFALDLELY RYSGVNMTGF RLLNIDNPHV SSIIEKWSME 
RLQAPPRPET GLLDGMMTTE AALMYDAVYM VAIASHRASQ LTVSSLQCHR HKPWRLGPRF 
MNLIKEARWD GLTGHITFNK TNGLRKDFDL DIISLKEEGT EKIGIWNSNS GLNMTDSNKD 
KSSNITDSLA NRTLIVTTIL EEPYVMYRKS DKPLYGNDRF EGYCLDLLKE LSNILGFIYD 
VKLVPDGKYG AQNDKGEWNG MVKELIDHRA DLAVAPLTIT YVREKVIDFS KPFMTLGISI 
LYRKPNGTNP GVFSFLNPLS PDIWMYVLLA CLGVSCVLFV IARFTPYEWY NPHPCNPDSD 
VVENNFTLLN SFWFGVGALM QQGSELMPKA LSTRIVGGIW WFFTLIIISS YTANLAAFLT 
VERMESPIDS ADDLAKQTKI EYGAVRDGST MTFFKKSKIS TYEKMWAFMS SRQQTALVRN 
SDEGIQRVLT TDYALLMEST SIEYVTQRNC NLTQIGGLID SKGYGVGTPI GSPYRDKITI 
AILQLQEEGK LHMMKEKWWR GNGCPEEDNK EASALGVENI GGIFIVLAAG LVLSVFVAIG 
EFIYKSRKNN DIEQKGKSSR IRFYFRNKVR FHGRKKQSLG VEKCLSFNAI MEELGISLKN 
QKKIKKKSRT KGKSSFTSIL TCHQRRTQRK ETVA

Genular Protein ID: 2801813640

Symbol: E9PD61_HUMAN

Name: N/A

UniProtKB Accession Codes:

E9PD61

Database IDs:

ARBA 12 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 7 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 3 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 6 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 2 RefSeq 1 RuleBase 1 SMART 4 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

Sequence Information:

  • Length: 920
  • Mass: 104357
  • Checksum: EB4E4517F28A5FBF
  • Sequence:
    • MEHGTLLAQP GLWTRDTSWA LLYFLCYILP QTAPQVLRIG GIFETVENEP VNVEELAFKF 
AVTSINRNRT LMPNTTLTYD IQRINLFDSF EASRRACDQL ALGVAALFGP SHSSSVSAVQ 
SICNALEVPH IQTRWKHPSV DNKDLFYINL YPDYAAISRA ILDLVLYYNW KTVTVVYEDS 
TGLIRLQELI KAPSRYNIKI KIRQLPSGNK DAKPLLKEMK KGKEFYVIFD CSHETAAEIL 
KQILFMGMMT EYYHYFFTTL DLFALDLELY RYSGVNMTGF RLLNIDNPHV SSIIEKWSME 
RLQAPPRPET GLLDGMMTTE AALMYDAVYM VAIASHRASQ LTVSSLQCHR HKPWRLGPRF 
MNLIKEARWD GLTGHITFNK TNGLRKDFDL DIISLKEEGT EKAAGEVSKH LYKVWKKIGI 
WNSNSGLNMT DSNKDKSSNI TDSLANRTLI VTTILEEPYV MYRKSDKPLY GNDRFEGYCL 
DLLKELSNIL GFIYDVKLVP DGKYGAQNDK GEWNGMVKEL IDHRADLAVA PLTITYVREK 
VIDFSKPFMT LGISILYRKP NGTNPGVFSF LNPLSPDIWM YVLLACLGVS CVLFVIARFT 
PYEWYNPHPC NPDSDVVENN FTLLNSFWFG VGALMQQGSE LMPKALSTRI VGGIWWFFTL 
IIISSYTANL AAFLTVERME SPIDSADDLA KQTKIEYGAV RDGSTMTFFK KSKISTYEKM 
WAFMSSRQQT ALVRNSDEGI QRVLTTDYAL LMESTSIEYV TQRNCNLTQI GGLIDSKGYG 
VGTPIGSPYR DKITIAILQL QEEGKLHMMK EKWWRGNGCP EEDNKEASAL GVENIGGIFI 
VLAAGLVLSV FVAIGEFIYK SRKNNDIEQC LSFNAIMEEL GISLKNQKKI KKKSRTKGKS 
SFTSILTCHQ RRTQRKETVA

Genular Protein ID: 2653152638

Symbol: E7ENK3_HUMAN

Name: N/A

UniProtKB Accession Codes:

E7ENK3

Database IDs:

ARBA 12 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 7 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 3 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 6 MANE-Select 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 2 Pfam 3 PhylomeDB 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 RuleBase 1 SMART 4 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

Sequence Information:

  • Length: 949
  • Mass: 107877
  • Checksum: 789FFDC10F544395
  • Sequence:
    • MEHGTLLAQP GLWTRDTSWA LLYFLCYILP QTAPQVLRIG GIFETVENEP VNVEELAFKF 
AVTSINRNRT LMPNTTLTYD IQRINLFDSF EASRRACDQL ALGVAALFGP SHSSSVSAVQ 
SICNALEVPH IQTRWKHPSV DNKDLFYINL YPDYAAISRA ILDLVLYYNW KTVTVVYEDS 
TGLIRLQELI KAPSRYNIKI KIRQLPSGNK DAKPLLKEMK KGKEFYVIFD CSHETAAEIL 
KQILFMGMMT EYYHYFFTTL DLFALDLELY RYSGVNMTGF RLLNIDNPHV SSIIEKWSME 
RLQAPPRPET GLLDGMMTTE AALMYDAVYM VAIASHRASQ LTVSSLQCHR HKPWRLGPRF 
MNLIKEARWD GLTGHITFNK TNGLRKDFDL DIISLKEEGT EKAAGEVSKH LYKVWKKIGI 
WNSNSGLNMT DSNKDKSSNI TDSLANRTLI VTTILEEPYV MYRKSDKPLY GNDRFEGYCL 
DLLKELSNIL GFIYDVKLVP DGKYGAQNDK GEWNGMVKEL IDHRADLAVA PLTITYVREK 
VIDFSKPFMT LGISILYRKP NGTNPGVFSF LNPLSPDIWM YVLLACLGVS CVLFVIARFT 
PYEWYNPHPC NPDSDVVENN FTLLNSFWFG VGALMQQGSE LMPKALSTRI VGGIWWFFTL 
IIISSYTANL AAFLTVERME SPIDSADDLA KQTKIEYGAV RDGSTMTFFK KSKISTYEKM 
WAFMSSRQQT ALVRNSDEGI QRVLTTDYAL LMESTSIEYV TQRNCNLTQI GGLIDSKGYG 
VGTPIGSPYR DKITIAILQL QEEGKLHMMK EKWWRGNGCP EEDNKEASAL GVENIGGIFI 
VLAAGLVLSV FVAIGEFIYK SRKNNDIEQK GKSSRIRFYF RNKVRFHGRK KQSLGVEKCL 
SFNAIMEELG ISLKNQKKIK KKSRTKGKSS FTSILTCHQR RTQRKETVA

Genular Protein ID: 2981255520

Symbol: B7Z3V7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z3V7

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 2 Gene3D 3 GenomeRNAi 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 1 Pfam 3 RefSeq 3 RuleBase 1 SMART 4 SUPFAM 2

Sequence Information:

  • Length: 920
  • Mass: 104351
  • Checksum: BAE4AFB855230327
  • Sequence:
    • MEHGTLLAQP GLWTRDTSWA LLYFLCYILP QTAPQVLRIG GIFETVENEP VNVEELAFKF 
AVTSINRNRT LMPNTTLTYD IQRINLFDSF EASRRACDQL ALGVAALFGP SHSSSVSAVQ 
SICNALEVPH IQTRWKHPSV DNKDLFYINL YPDYAAISRA ILDLVLYYNW KTVTVVYEDS 
TGLIRLQELI KAPSRYNIKI KIRQLPSGNK DAKPLLKEMK KGKEFYVIFD CSHETAAEIL 
KQILFMGMMT EYYHYFFTTL DLFALDLELY RYSGVNMTGF RLLNIDNPHV SSIIEKWSME 
RLQAPPRPET GLLDGMMTTE AALMYDAVYM VAIASHRASQ LTVSSLQCHR HKPWRLGPRF 
MNLIKEARWD GLTGHITFNK TNGLRKDFDL DIISLKEEGT EKAAGEVSKH LYKVWKKIGI 
WNSNSGLNMT DSNKDKSSNI TDSLANRTLI VTTILEEPYV MYRKSDKPLY GNDRFEGYCL 
DLLKELSNIL GFIYDVKLVP DGKYGAQNDK GEWNGMVKEL IDHRADLAVA PLTITYVREK 
VIDFSKPFMT LGISILYRKP NGTNPGVFSF LNPLSPDIWM YVLLACLGVS CVLFVIARFT 
PYEWYNPHPC NPDSDVVENN FTLLNSFWFG VGALMRQGSE LMPKALSTRI VGGIWWFFTL 
IIISSYTANL AAFLTVERME SPIDSADDLA KQTKIEYGAV RDGSTMTLFK KSKISTYEKM 
WAFMSSRQQT ALVRNSDEGI QRVLTTDYAL LMESTSIEYV TQRNCNLTQI GGLIDSKGYG 
VGTPIGSPYR DKITIAILQL QEEGKLHMMK EKWWRGNGCP EEDNKEASAL GVENIGGIFI 
VLAAGLVLSV FVAIGEFIYK SRKNNDIEQC LSFNAIMEEL GISLKNQKKI KKKSRTKGKS 
SFTSILTCHQ RRTQRKETVA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.