Details for: ASTE1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 67.5045
Cell Significance Index: -10.5000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 40.1548
Cell Significance Index: -10.1900 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 25.5011
Cell Significance Index: -10.3600 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 24.6334
Cell Significance Index: -11.6300 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 10.8511
Cell Significance Index: -10.3600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 9.0514
Cell Significance Index: -11.1600 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 4.0166
Cell Significance Index: -10.7600 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 2.8674
Cell Significance Index: -11.3200 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: 1.8242
Cell Significance Index: 30.0600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.8872
Cell Significance Index: 87.7600 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.8493
Cell Significance Index: 50.9900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.7456
Cell Significance Index: 673.1900 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.6689
Cell Significance Index: 72.7600 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.4976
Cell Significance Index: 80.9400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.3583
Cell Significance Index: 24.7800 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.3346
Cell Significance Index: 7.2500 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.2976
Cell Significance Index: 13.4900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2754
Cell Significance Index: 52.4100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.2435
Cell Significance Index: 48.8400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2230
Cell Significance Index: 6.4300 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 0.2124
Cell Significance Index: 2.1300 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.2009
Cell Significance Index: 4.4000 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.1436
Cell Significance Index: 8.0600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.1319
Cell Significance Index: 26.1800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1191
Cell Significance Index: 21.4700 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 0.1188
Cell Significance Index: 1.7900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.1056
Cell Significance Index: 2.6400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1033
Cell Significance Index: 37.0600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1006
Cell Significance Index: 13.8200 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0713
Cell Significance Index: 31.5200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.0710
Cell Significance Index: 3.6900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0704
Cell Significance Index: 8.6600 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.0685
Cell Significance Index: 4.3200 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0547
Cell Significance Index: 37.8000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0542
Cell Significance Index: 29.5900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0379
Cell Significance Index: 2.9100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0356
Cell Significance Index: 1.2500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.0352
Cell Significance Index: 2.2700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.0340
Cell Significance Index: 4.0100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0337
Cell Significance Index: 2.3800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.0326
Cell Significance Index: 4.7400 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0305
Cell Significance Index: 3.9100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.0228
Cell Significance Index: 2.6600 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.0075
Cell Significance Index: 0.2000 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0061
Cell Significance Index: 8.3000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0005
Cell Significance Index: 0.3400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0002
Cell Significance Index: 0.3700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0015
Cell Significance Index: -2.3800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0016
Cell Significance Index: -2.9500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0034
Cell Significance Index: -0.1600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0094
Cell Significance Index: -6.9000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0122
Cell Significance Index: -9.2300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0124
Cell Significance Index: -9.1700 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0139
Cell Significance Index: -6.3200 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0161
Cell Significance Index: -0.5200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0173
Cell Significance Index: -9.7500 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0194
Cell Significance Index: -1.1900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0216
Cell Significance Index: -3.6900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0216
Cell Significance Index: -13.4600 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0259
Cell Significance Index: -7.4600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0277
Cell Significance Index: -2.8300 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.0313
Cell Significance Index: -0.8000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0397
Cell Significance Index: -4.5500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0450
Cell Significance Index: -1.9900 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.0463
Cell Significance Index: -0.9700 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0478
Cell Significance Index: -0.8000 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0549
Cell Significance Index: -7.0900 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.0560
Cell Significance Index: -0.5800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0571
Cell Significance Index: -2.6900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0585
Cell Significance Index: -12.3300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0632
Cell Significance Index: -4.7100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0641
Cell Significance Index: -1.7900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0663
Cell Significance Index: -3.4800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0712
Cell Significance Index: -2.7000 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0753
Cell Significance Index: -5.0600 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0823
Cell Significance Index: -2.2400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0849
Cell Significance Index: -2.2800 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.0856
Cell Significance Index: -1.0200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1064
Cell Significance Index: -11.0800 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1065
Cell Significance Index: -2.8000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1105
Cell Significance Index: -2.9500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1148
Cell Significance Index: -7.0400 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.1148
Cell Significance Index: -2.2400 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1342
Cell Significance Index: -10.6300 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1434
Cell Significance Index: -7.4700 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1456
Cell Significance Index: -5.0600 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.1529
Cell Significance Index: -2.6200 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1606
Cell Significance Index: -3.4200 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1758
Cell Significance Index: -4.5200 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.1825
Cell Significance Index: -5.3600 - Cell Name: peg cell (CL4033014)
Fold Change: -0.2078
Cell Significance Index: -4.8000 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2095
Cell Significance Index: -6.8600 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.2181
Cell Significance Index: -11.0200 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.2215
Cell Significance Index: -7.0600 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.2315
Cell Significance Index: -8.1100 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.2423
Cell Significance Index: -5.8100 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.2425
Cell Significance Index: -7.6700 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.2523
Cell Significance Index: -3.7300 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.2690
Cell Significance Index: -3.6700 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.2709
Cell Significance Index: -5.7500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3048814182
Symbol: ASTE1_HUMAN
Name: Single-strand DNA endonuclease ASTE1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 10931946
Title: Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.
PubMed ID: 10931946
PubMed ID: 34354233
Title: ASTE1 promotes shieldin-complex-mediated DNA repair by attenuating end resection.
PubMed ID: 34354233
Sequence Information:
- Length: 679
- Mass: 77093
- Checksum: 488DE83A8CD8E82B
- Sequence:
MGIRGLMSFV EDHSNEFFTD LKLRDTKIVI DGYALFHRLC FSSNLDLRYG GDYDSFADVV QKFFESLFAC NICPYVVLDG GCDISDKKLT TLKDRAREKI QMAHSLSVGG SGYVCPLLIR EVFIQVLIKL RVCFVQCFSE ADRDIMTLAN HWNCPVLSSD SDFCIFDLKT GFCPLNSFQW RNMNTIKGTQ NYIPAKCFSL DAFCHHFSNM NKALLPLFAV LCGNDHVNLP IMETFLSKAR LPLGATSSKG RRHHRILGLL NWLSHFANPT EALDNVLKYL PKKDRENVKE LLCCSMEEYQ QSQVKLQDFF QCGTYVCPDA LNLGLPEWVL VALAKGQLSP FISDALVLRR TILPTQVENM QQPNAHRISQ PIRQIIYGLL LNASPHLDKT SWNALPPQPL AFSEVERINK NIRTSIIDAV ELAKDHSDLS RLTELSLRRR QMLLLETLKV KQTILEPIPT SLKLPIAVSC YWLQHTETKA KLHHLQSLLL TMLVGPLIAI INSPGKEELQ EDGAKMLYAE FQRVKAQTRL GTRLDLDTAH IFCQWQSCLQ MGMYLNQLLS TPLPEPDLTR LYSGSLVHGL CQQLLASTSV ESLLSICPEA KQLYEYLFNA TRSYAPAEIF LPKGRSNSKK KRQKKQNTSC SKNRGRTTAH TKCWYEGNNR FGLLMVENLE EHSEASNIE
Genular Protein ID: 2428194485
Symbol: D6RG30_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 11181995
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
Sequence Information:
- Length: 704
- Mass: 79920
- Checksum: C70FC41C88F37304
- Sequence:
MGIRGLMSFV EDHSNEFFTD LKLRDTKIVI DGYALFHRLC FSSNLDLRYG GDYDSFADVV QKFFESLFAC NICPYVVLDG GCDISDKKLT TLKDRAREKI QMAHSLSVGG SGYVCPLLIR EVFIQVLIKL RVCFVQCFSE ADRDIMTLAN HWNCPVLSSD SDFCIFDLKT GFCPLNSFQW RNMNTIKGTQ NYIPAKCFSL DAFCHHFSNM NKALLPLFAV LCGNDHVNLP IMETFLSKAR LPLGATSSKG RRHHRILGLL NWLSHFANPT EALDNVLKYL PKKDRENVKE LLCCSMEEYQ QSQVKLQDFF QCGTYVCPDA LNLGLPEWVL VALAKGQLSP FISDALVLRR TILPTQVENM QQPNAHRISQ PIRQIIYGLL LNASPHLDKT SWNALPPQPL AFSEVERINK NIRTSIIDAV ELAKDHSDLS RLTELSLRRR QMLLLETLKV KQTILEPIPT SLKLPIAVSC YWLQHTETKA KLHHLQSLLL TMLVGPLIAI INSPGKEELQ EDGAKMLYAE FQRVKAQTRL GTRLDLDTAH IFCQWQSCLQ MGMYLNQLLS TPLPEPDLTR PSAFNTLNED IWTHTKYGGT LHVSRLYSGS LVHGLCQQLL ASTSVESLLS ICPEAKQLYE YLFNATRSYA PAEIFLPKGR SNSKKKRQKK QNTSCSKNRG RTTAHTKCWY EGNNRFGLLM VENLEEHSEA SNIE
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.