Details for: GRM5

Gene ID: 2915

Symbol: GRM5

Ensembl ID: ENSG00000168959

Description: glutamate metabotropic receptor 5

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 6.7460
    Cell Significance Index: 298.3900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 6.6771
    Cell Significance Index: 252.8500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 6.5358
    Cell Significance Index: 186.5100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 6.0479
    Cell Significance Index: 406.6600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 4.9097
    Cell Significance Index: 1761.0100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 3.7602
    Cell Significance Index: 2600.6700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 3.5945
    Cell Significance Index: 721.0600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 3.2474
    Cell Significance Index: 199.6000
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 2.9086
    Cell Significance Index: 37.7200
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 2.6387
    Cell Significance Index: 35.2000
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 2.1432
    Cell Significance Index: 51.4000
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 0.6767
    Cell Significance Index: 5.1900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 0.2240
    Cell Significance Index: 4.4300
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.0704
    Cell Significance Index: 0.6700
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: 0.0064
    Cell Significance Index: 0.0700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0293
    Cell Significance Index: -55.1000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0367
    Cell Significance Index: -67.6800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0425
    Cell Significance Index: -65.3800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0434
    Cell Significance Index: -59.0500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0913
    Cell Significance Index: -66.9300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0977
    Cell Significance Index: -62.0300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.1034
    Cell Significance Index: -78.2600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.1047
    Cell Significance Index: -77.5700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1145
    Cell Significance Index: -2.4300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1275
    Cell Significance Index: -79.6400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.1281
    Cell Significance Index: -69.9500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1303
    Cell Significance Index: -73.4900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1434
    Cell Significance Index: -65.0800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1452
    Cell Significance Index: -2.0800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1750
    Cell Significance Index: -5.7300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2002
    Cell Significance Index: -57.6000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.3439
    Cell Significance Index: -61.9900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.3758
    Cell Significance Index: -74.5700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3770
    Cell Significance Index: -79.4100
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.3797
    Cell Significance Index: -4.4300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.4070
    Cell Significance Index: -59.1600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4182
    Cell Significance Index: -13.3200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.4492
    Cell Significance Index: -76.7000
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.4985
    Cell Significance Index: -6.2900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.5005
    Cell Significance Index: -61.5400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.5102
    Cell Significance Index: -70.0600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.5979
    Cell Significance Index: -16.7100
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.6203
    Cell Significance Index: -5.8800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.6552
    Cell Significance Index: -68.2200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.6724
    Cell Significance Index: -68.6900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.6750
    Cell Significance Index: -77.3400
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.7693
    Cell Significance Index: -16.6200
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.8036
    Cell Significance Index: -9.6100
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.8390
    Cell Significance Index: -16.8500
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.8583
    Cell Significance Index: -12.0300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.8719
    Cell Significance Index: -66.9100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.9537
    Cell Significance Index: -23.7900
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: -1.0104
    Cell Significance Index: -8.7400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -1.0432
    Cell Significance Index: -58.5400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.0530
    Cell Significance Index: -36.8900
  • Cell Name: chandelier cell (CL4023083)
    Fold Change: -1.1332
    Cell Significance Index: -9.1500
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -1.2180
    Cell Significance Index: -25.4200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.2770
    Cell Significance Index: -67.0500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -1.3393
    Cell Significance Index: -69.7600
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: -1.3560
    Cell Significance Index: -17.7600
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: -1.4312
    Cell Significance Index: -15.7900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -1.5268
    Cell Significance Index: -71.7600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -1.5404
    Cell Significance Index: -33.7300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -1.5411
    Cell Significance Index: -26.4100
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -1.5484
    Cell Significance Index: -19.2100
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -1.5965
    Cell Significance Index: -19.3500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.6646
    Cell Significance Index: -86.4700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -1.7008
    Cell Significance Index: -79.3000
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: -1.7800
    Cell Significance Index: -13.9600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.9764
    Cell Significance Index: -68.6800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.9864
    Cell Significance Index: -72.9200
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: -2.0829
    Cell Significance Index: -18.8300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -2.0866
    Cell Significance Index: -73.3200
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -2.2178
    Cell Significance Index: -53.7200
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -2.2391
    Cell Significance Index: -44.6500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -2.2716
    Cell Significance Index: -48.5600
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -2.2877
    Cell Significance Index: -30.5000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -2.3101
    Cell Significance Index: -59.3800
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -2.3208
    Cell Significance Index: -45.6800
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -2.3273
    Cell Significance Index: -73.6100
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -2.3423
    Cell Significance Index: -15.8700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -2.3637
    Cell Significance Index: -69.6200
  • Cell Name: intratelencephalic-projecting glutamatergic cortical neuron (CL4023008)
    Fold Change: -2.4492
    Cell Significance Index: -25.1800
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -2.4534
    Cell Significance Index: -42.4200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -2.5399
    Cell Significance Index: -73.1800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -2.5431
    Cell Significance Index: -72.9000
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -2.5723
    Cell Significance Index: -52.3400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -2.6508
    Cell Significance Index: -70.7800
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -2.7000
    Cell Significance Index: -68.7900
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -2.7661
    Cell Significance Index: -36.1000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -2.7891
    Cell Significance Index: -73.3400
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -2.9117
    Cell Significance Index: -72.6100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -2.9387
    Cell Significance Index: -73.4600
  • Cell Name: peg cell (CL4033014)
    Fold Change: -2.9628
    Cell Significance Index: -68.4500
  • Cell Name: L5/6 near-projecting glutamatergic neuron of the primary motor cortex (CL4023043)
    Fold Change: -3.0066
    Cell Significance Index: -30.3800
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -3.0109
    Cell Significance Index: -75.2000
  • Cell Name: invaginating midget bipolar cell (CL4033034)
    Fold Change: -3.0504
    Cell Significance Index: -37.6500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -3.1849
    Cell Significance Index: -85.3400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -3.2128
    Cell Significance Index: -87.4500
  • Cell Name: flat midget bipolar cell (CL4033033)
    Fold Change: -3.2156
    Cell Significance Index: -39.9700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Structure and Function:** GRM5 is a G-protein-coupled receptor (GPCR) that responds to glutamate, the primary excitatory neurotransmitter in the brain. It is composed of seven transmembrane domains and is coupled to various signaling pathways, including adenylate cyclase inhibition and phospholipase C activation. 2. **Expression Pattern:** GRM5 is highly expressed in the cerebral cortex, hippocampus, and other brain regions, with significant presence in inhibitory interneurons and pyramidal neurons. 3. **Signaling Pathways:** GRM5 is involved in multiple signaling pathways, including adenylate cyclase inhibition, phospholipase C activation, and calcium-mediated signaling. These pathways regulate various cellular processes, including neuronal excitability, synaptic plasticity, and gene expression. 4. **Regulation of Synaptic Transmission:** GRM5 modulates synaptic transmission by regulating the release of neurotransmitters, such as glutamate and GABA, and influencing the activity of ion channels and receptors. **Pathways and Functions:** 1. **Adenylate Cyclase Inhibition:** GRM5 activation leads to the inhibition of adenylate cyclase, resulting in decreased cAMP levels and reduced neuronal excitability. 2. **Phospholipase C Activation:** GRM5 activation also activates phospholipase C, leading to the production of inositol trisphosphate (IP3) and diacylglycerol (DAG), which regulate calcium signaling and neuronal excitability. 3. **Calcium-Mediated Signaling:** GRM5 modulates intracellular calcium signaling, influencing neuronal excitability and synaptic transmission. 4. **Regulation of Synaptic Plasticity:** GRM5 is involved in regulating synaptic plasticity, including long-term potentiation (LTP) and long-term depression (LTD), which are essential for learning and memory. 5. **Regulation of Gene Expression:** GRM5 regulates gene expression by modulating the activity of transcription factors and other regulatory proteins. **Clinical Significance:** 1. **Neurodegenerative Diseases:** GRM5 has been implicated in the pathogenesis of various neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. Dysregulation of GRM5 signaling has been linked to disease progression and cognitive decline. 2. **Cognitive Function:** GRM5 plays a crucial role in regulating cognitive function, including attention, memory, and learning. Alterations in GRM5 expression and signaling have been associated with cognitive impairments in various neurological disorders. 3. **Therapeutic Targets:** GRM5 has emerged as a potential therapeutic target for the treatment of neurological disorders, including Alzheimer's disease, Parkinson's disease, and depression. Modulating GRM5 signaling may provide novel therapeutic strategies for the treatment of these conditions. In conclusion, GRM5 is a critical component of the glutamatergic system, playing a pivotal role in regulating various aspects of neuronal function, including cognition, learning, and synaptic plasticity. Further research is needed to fully elucidate the role of GRM5 in neurological function and to explore its therapeutic potential in the treatment of neurodegenerative diseases and cognitive disorders.

Genular Protein ID: 3910795295

Symbol: GRM5_HUMAN

Name: Metabotropic glutamate receptor 5

UniProtKB Accession Codes:

P41594 Q6J164

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CTD 1 ChEBI 6 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 4 DrugCentral 1 EMBL 10 EMDB 9 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 35 Gene3D 2 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 15 PDBsum 15 PIR 2 PRINTS 3 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 3 RefSeq 5 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7908515

Title: Molecular cloning and the functional expression of two isoforms of human metabotropic glutamate receptor subtype 5.

PubMed ID: 7908515

DOI: 10.1006/bbrc.1994.1349

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 7688218

Title: A variant of metabotropic glutamate receptor subtype 5: an evolutionally conserved insertion with no termination codon.

PubMed ID: 7688218

DOI: 10.1006/bbrc.1993.1866

PubMed ID: 19694902

Title: The association of metabotropic glutamate receptor type 5 with the neuronal Ca2+-binding protein 2 modulates receptor function.

PubMed ID: 19694902

DOI: 10.1111/j.1471-4159.2009.06348.x

PubMed ID: 28130356

Title: Mutation Disrupts Dendritic Morphology and Synaptic Transmission, and Causes ASD-Related Behaviors.

PubMed ID: 28130356

DOI: 10.1523/jneurosci.2068-16.2017

PubMed ID: 25042998

Title: Structure of class C GPCR metabotropic glutamate receptor 5 transmembrane domain.

PubMed ID: 25042998

DOI: 10.1038/nature13396

Sequence Information:

  • Length: 1212
  • Mass: 132469
  • Checksum: A3C73606681C6A25
  • Sequence:
    • MVLLLILSVL LLKEDVRGSA QSSERRVVAH MPGDIIIGAL FSVHHQPTVD KVHERKCGAV 
REQYGIQRVE AMLHTLERIN SDPTLLPNIT LGCEIRDSCW HSAVALEQSI EFIRDSLISS 
EEEEGLVRCV DGSSSSFRSK KPIVGVIGPG SSSVAIQVQN LLQLFNIPQI AYSATSMDLS 
DKTLFKYFMR VVPSDAQQAR AMVDIVKRYN WTYVSAVHTE GNYGESGMEA FKDMSAKEGI 
CIAHSYKIYS NAGEQSFDKL LKKLTSHLPK ARVVACFCEG MTVRGLLMAM RRLGLAGEFL 
LLGSDGWADR YDVTDGYQRE AVGGITIKLQ SPDVKWFDDY YLKLRPETNH RNPWFQEFWQ 
HRFQCRLEGF PQENSKYNKT CNSSLTLKTH HVQDSKMGFV INAIYSMAYG LHNMQMSLCP 
GYAGLCDAMK PIDGRKLLES LMKTNFTGVS GDTILFDENG DSPGRYEIMN FKEMGKDYFD 
YINVGSWDNG ELKMDDDEVW SKKSNIIRSV CSEPCEKGQI KVIRKGEVSC CWTCTPCKEN 
EYVFDEYTCK ACQLGSWPTD DLTGCDLIPV QYLRWGDPEP IAAVVFACLG LLATLFVTVV 
FIIYRDTPVV KSSSRELCYI ILAGICLGYL CTFCLIAKPK QIYCYLQRIG IGLSPAMSYS 
ALVTKTNRIA RILAGSKKKI CTKKPRFMSA CAQLVIAFIL ICIQLGIIVA LFIMEPPDIM 
HDYPSIREVY LICNTTNLGV VTPLGYNGLL ILSCTFYAFK TRNVPANFNE AKYIAFTMYT 
TCIIWLAFVP IYFGSNYKII TMCFSVSLSA TVALGCMFVP KVYIILAKPE RNVRSAFTTS 
TVVRMHVGDG KSSSAASRSS SLVNLWKRRG SSGETLRYKD RRLAQHKSEI ECFTPKGSMG 
NGGRATMSSS NGKSVTWAQN EKSSRGQHLW QRLSIHINKK ENPNQTAVIK PFPKSTESRG 
LGAGAGAGGS AGGVGATGGA GCAGAGPGGP ESPDAGPKAL YDVAEAEEHF PAPARPRSPS 
PISTLSHRAG SASRTDDDVP SLHSEPVARS SSSQGSLMEQ ISSVVTRFTA NISELNSMML 
STAAPSPGVG APLCSSYLIP KEIQLPTTMT TFAEIQPLPA IEVTGGAQPA AGAQAAGDAA 
RESPAAGPEA AAAKPDLEEL VALTPPSPFR DSVDSGSTTP NSPVSESALC IPSSPKYDTL 
IIRDYTQSSS SL

Genular Protein ID: 1988594725

Symbol: A8K5P7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K5P7

Database IDs:

ARBA 12 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 2 InterPro 10 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 5 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 1 SAM 2 SUPFAM 1

Sequence Information:

  • Length: 905
  • Mass: 101417
  • Checksum: 078564EFCC85E93B
  • Sequence:
    • MVLLLILSVL LLKEDVRGSA QSSERRVVAH MPGDIIIGAL FSVHHQPTVD KVHERKCGAV 
REQYGIQRVE AMLHTLERIN SDPTLLPNIT LGCEIRDSCW HSAVALEQSI EFIRDSLISS 
EEEEGLVRCV DGSSSSFRSK KPIVGVIGPG SSSVAIQVQN LLQLFNIPQI AYSATSMDLS 
DKTLFKYFMR VVPSDAQQAR AMVDIVKRYN WTYVSAVHTE GNYGESGMEA FKDMSAKEGI 
CIAHSYKIYS NAGEQSFDKL LKKLTSHLPK ARVVACFCEG MTVRGLLMAM RRLGLAGEFL 
LLGSDGWADR YDVTDGYQRE AVGGITIKLQ SPDVKWFDDY YLKLRPETNH RNPWFQEFWQ 
HRFQCRLEGF PQENSKYNKT CNSSLTLKTH HVQDSKMGFV INAIYSMAYG LHNMQMSLCP 
GYAGLCDAMK PIDGRKLLES LMKTNFTGVS GDTILFDENG DSPGRYEIMN FKEMGKDYFD 
YINVGSWDNG ELKMDDDEVW SKKSNIIRSV CSEPCEKGQI KVIRKGEVSC CWTCTPCKEN 
EYVFDEYTCK ACQLGSWPTD DLTGCDLIPV QYLRWGDPEP IAAVVFACLG LLATLFVTVV 
FIIYRDTPVV KSSSRELCYI ILAGICLGYL CTFCLIAKPK QIYCYLQRIG IGLSPAMSYS 
ALVTKTNRIA RILAGSKKKI CTKKPRFMSA CAQLVIAFIL ICIQLGIIVA LFIMEPPDIM 
HDYPSIREVY LICNTTNLGV VTPLGYNGLL ILSCTFYAFK TRNVPANFNE AKYIAFTMYT 
TCIIWLAFVP IYFGSNYKII TMCFSVSLSA TVALGCMFVP KVYIILAKPE RNVRSAFTTS 
TVVRMHVGDG KSSSAASRSS SLVNLWKRRG SSGETLSSNG KSVTWAQNEK SSRGQHLWQR 
LSIHI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.