Details for: GTF3C1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 210.3568
Cell Significance Index: -32.7200 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 128.8423
Cell Significance Index: -32.6800 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 75.1076
Cell Significance Index: -35.4600 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 69.1680
Cell Significance Index: -28.1000 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 29.5786
Cell Significance Index: -28.2400 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 27.1664
Cell Significance Index: -33.5000 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 12.6658
Cell Significance Index: -33.9300 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 10.3388
Cell Significance Index: -31.7600 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 8.5554
Cell Significance Index: -33.7600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 7.7173
Cell Significance Index: -16.8900 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 2.1116
Cell Significance Index: 28.8100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.4598
Cell Significance Index: 292.8400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.3627
Cell Significance Index: 1230.4300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.0830
Cell Significance Index: 214.9300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.9728
Cell Significance Index: 74.6500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.9726
Cell Significance Index: 27.1800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.9056
Cell Significance Index: 324.8100 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.8877
Cell Significance Index: 96.5500 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.8680
Cell Significance Index: 141.1800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.7542
Cell Significance Index: 33.3600 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.7117
Cell Significance Index: 26.9500 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.7088
Cell Significance Index: 42.5500 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.6306
Cell Significance Index: 436.1300 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.6301
Cell Significance Index: 32.8200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.5813
Cell Significance Index: 39.0900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.5521
Cell Significance Index: 13.8000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.5155
Cell Significance Index: 13.2500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4931
Cell Significance Index: 48.7800 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.4439
Cell Significance Index: 835.8900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.4347
Cell Significance Index: 237.4100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.4261
Cell Significance Index: 76.8200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.4072
Cell Significance Index: 22.8500 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.4010
Cell Significance Index: 11.5600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.3067
Cell Significance Index: 18.8500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.3065
Cell Significance Index: 37.6900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.3042
Cell Significance Index: 6.5900 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.2980
Cell Significance Index: 131.7400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.2961
Cell Significance Index: 13.4200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.2517
Cell Significance Index: 34.5700 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.2458
Cell Significance Index: 15.4900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1555
Cell Significance Index: 29.6000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1096
Cell Significance Index: 3.8500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0952
Cell Significance Index: 16.2500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0950
Cell Significance Index: 146.2600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0865
Cell Significance Index: 159.5700 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0733
Cell Significance Index: 46.5500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0638
Cell Significance Index: 28.9700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.0512
Cell Significance Index: 2.6600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0492
Cell Significance Index: 2.3000 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0349
Cell Significance Index: 47.4400 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.0100
Cell Significance Index: 0.2400 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0028
Cell Significance Index: -0.3600 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0051
Cell Significance Index: -0.6000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0121
Cell Significance Index: -8.9300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0222
Cell Significance Index: -0.3800 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0245
Cell Significance Index: -17.9900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0252
Cell Significance Index: -15.7400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0328
Cell Significance Index: -24.8100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0380
Cell Significance Index: -21.4300 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.0697
Cell Significance Index: -0.8700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0890
Cell Significance Index: -12.9300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0919
Cell Significance Index: -19.3600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1008
Cell Significance Index: -10.3000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1019
Cell Significance Index: -29.3300 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1058
Cell Significance Index: -7.4800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1135
Cell Significance Index: -13.2300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1189
Cell Significance Index: -7.6700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1527
Cell Significance Index: -17.5000 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.1554
Cell Significance Index: -4.1700 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.1684
Cell Significance Index: -4.8100 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1835
Cell Significance Index: -4.8300 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.2031
Cell Significance Index: -26.2500 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2149
Cell Significance Index: -4.2000 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2388
Cell Significance Index: -11.2300 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.2438
Cell Significance Index: -3.6000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2449
Cell Significance Index: -25.5100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.2507
Cell Significance Index: -6.7000 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.2878
Cell Significance Index: -6.1300 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.3014
Cell Significance Index: -34.4100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.3438
Cell Significance Index: -18.0500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.3464
Cell Significance Index: -25.8200 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3575
Cell Significance Index: -11.4500 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.3586
Cell Significance Index: -7.6700 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.3778
Cell Significance Index: -10.8300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3784
Cell Significance Index: -29.9700 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.3798
Cell Significance Index: -8.0600 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.4077
Cell Significance Index: -4.8600 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.4422
Cell Significance Index: -6.3000 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.4580
Cell Significance Index: -7.6700 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.5003
Cell Significance Index: -10.9600 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.5019
Cell Significance Index: -17.4400 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.5188
Cell Significance Index: -14.1200 - Cell Name: peg cell (CL4033014)
Fold Change: -0.5255
Cell Significance Index: -12.1400 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.5393
Cell Significance Index: -33.0700 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.5687
Cell Significance Index: -11.2500 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.5721
Cell Significance Index: -18.2200 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: -0.5789
Cell Significance Index: -4.9200 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.6053
Cell Significance Index: -19.8200 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.6145
Cell Significance Index: -9.2600 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.6145
Cell Significance Index: -31.0600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 485202672
Symbol: TF3C1_HUMAN
Name: General transcription factor 3C polypeptide 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8127861
Title: Human transcription factor IIIC box B binding subunit.
PubMed ID: 8127861
PubMed ID: 10493829
Title: Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.
PubMed ID: 10493829
PubMed ID: 15616553
Title: The sequence and analysis of duplication-rich human chromosome 16.
PubMed ID: 15616553
DOI: 10.1038/nature03187
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8164661
Title: Cloning and characterization of an evolutionarily divergent DNA-binding subunit of mammalian TFIIIC.
PubMed ID: 8164661
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 17525332
Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
PubMed ID: 17525332
PubMed ID: 18220336
Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
PubMed ID: 18220336
DOI: 10.1021/pr0705441
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 18377933
Title: Regulation of RNA polymerase III transcription by Maf1 in mammalian cells.
PubMed ID: 18377933
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19299493
Title: Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery.
PubMed ID: 19299493
DOI: 10.1093/hmg/ddp134
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25755297
Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
PubMed ID: 25755297
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
Sequence Information:
- Length: 2109
- Mass: 238875
- Checksum: 37A03135EFE695FC
- Sequence:
MDALESLLDE VALEGLDGLC LPALWSRLET RVPPFPLPLE PCTQEFLWRA LATHPGISFY EEPRERPDLQ LQDRYEEIDL ETGILESRRD PVALEDVYPI HMILENKDGI QGSCRYFKER KNITNDIRTK SLQPRCTMVE AFDRWGKKLI IVASQAMRYR ALIGQEGDPD LKLPDFSYCI LERLGRSRWQ GELQRDLHTT AFKVDAGKLH YHRKILNKNG LITMQSHVIR LPTGAQQHSI LLLLNRFHVD RRSKYDILME KLSVMLSTRT NHIETLGKLR EELGLCERTF KRLYQYMLNA GLAKVVSLRL QEIHPECGPC KTKKGTDVMV RCLKLLKEFK RNDHDDDEDE EVISKTVPPV DIVFERDMLT QTYDLIERRG TKGISQAEIR VAMNVGKLEA RMLCRLLQRF KVVKGFMEDE GRQRTTKYIS CVFAEESDLS RQYQREKARS ELLTTVSLAS MQEESLLPEG EDTFLSESDS EEERSSSKRR GRGSQKDTRA SANLRPKTQP HHSTPTKGGW KVVNLHPLKK QPPSFPGAAE ERACQSLASR DSLLDTSSVS EPNVSFVSHC ADSNSGDIAV IEEVRMENPK ESSSSLKTGR HSSGQDKPHE TYRLLKRRNL IIEAVTNLRL IESLFTIQKM IMDQEKQEGV STKCCKKSIV RLVRNLSEEG LLRLYRTTVI QDGIKKKVDL VVHPSMDQND PLVRSAIEQV RFRISNSSTA NRVKTSQPPV PQGEAEEDSQ GKEGPSGSGD SQLSASSRSE SGRMKKSDNK MGITPLRNYH PIVVPGLGRS LGFLPKMPRL RVVHMFLWYL IYGHPASNTV EKPSFISERR TIKQESGRAG VRPSSSGSAW EACSEAPSKG SQDGVTWEAE VELATETVYV DDASWMRYIP PIPVHRDFGF GWALVSDILL CLPLSIFIQI VQVSYKVDNL EEFLNDPLKK HTLIRFLPRP IRQQLLYKRR YIFSVVENLQ RLCYMGLLQF GPTEKFQDKD QVFIFLKKNA VIVDTTICDP HYNLARSSRP FERRLYVLNS MQDVENYWFD LQCVCLNTPL GVVRCPRVRK NSSTDQGSDE EGSLQKEQES AMDKHNLERK CAMLEYTTGS REVVDEGLIP GDGLGAAGLD SSFYGHLKRN WIWTSYIINQ AKKENTAAEN GLTVRLQTFL SKRPMPLSAR GNSRLNIWGE ARVGSELCAG WEEQFEVDRE PSLDRNRRVR GGKSQKRKRL KKDPGKKIKR KKKGEFPGEK SKRLRYHDEA DQSALQRMTR LRVTWSMQED GLLVLCRIAS NVLNTKVKGP FVTWQVVRDI LHATFEESLD KTSHSVGRRA RYIVKNPQAY LNYKVCLAEV YQDKALVGDF MNRRGDYDDP KVCANEFKEF VEKLKEKFSS ALRNSNLEIP DTLQELFARY RVLAIGDEKD QTRKEDELNS VDDIHFLVLQ NLIQSTLALS DSQMKSYQSF QTFRLYREYK DHVLVKAFME CQKRSLVNRR RVNHTLGPKK NRALPFVPMS YQLSQTYYRI FTWRFPSTIC TESFQFLDRM RAAGKLDQPD RFSFKDQDNN EPTNDMVAFS LDGPGGNCVA VLTLFSLGLI SVDVRIPEQI IVVDSSMVEN EVIKSLGKDG SLEDDEDEED DLDEGVGGKR RSMEVKPAQA SHTNYLLMRG YYSPGIVSTR NLNPNDSIVV NSCQMKFQLR CTPVPARLRP AAAPLEELTM GTSCLPDTFT KLINPQENTC SLEEFVLQLE LSGYSPEDLT AALEILEAII ATGCFGIDKE ELRRRFSALE KAGGGRTRTF ADCIQALLEQ HQVLEVGGNT ARLVAMGSAW PWLLHSVRLK DREDADIQRE DPQARPLEGS SSEDSPPEGQ APPSHSPRGT KRRASWASEN GETDAEGTQM TPAKRPALQD SNLAPSLGPG AEDGAEAQAP SPPPALEDTA AAGAAQEDQE GVGEFSSPGQ EQLSGQAQPP EGSEDPRGFT ESFGAANISQ AARERDCESV CFIGRPWRVV DGHLNLPVCK GMMEAMLYHI MTRPGIPESS LLRHYQGVLQ PVAVLELLQG LESLGCIRKR WLRKPRPVSL FSTPVVEEVE VPSSLDESPM AFYEPTLDCT LRLGRVFPHE VNWNKWIHL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.