Details for: GTF3C1

Gene ID: 2975

Symbol: GTF3C1

Ensembl ID: ENSG00000077235

Description: general transcription factor IIIC subunit 1

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: germ cell (CL0000586)
    Fold Change: 2.31
    Marker Score: 4039
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.19
    Marker Score: 9180.5
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 2
    Marker Score: 2213.5
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.95
    Marker Score: 8088
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.64
    Marker Score: 60439
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.62
    Marker Score: 99340
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.59
    Marker Score: 31543
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.51
    Marker Score: 5835
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.5
    Marker Score: 14251.5
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.46
    Marker Score: 3440
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.44
    Marker Score: 54565
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.44
    Marker Score: 14828.5
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.42
    Marker Score: 12229.5
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.41
    Marker Score: 13306
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.41
    Marker Score: 1711
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.41
    Marker Score: 441
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.4
    Marker Score: 3077
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.4
    Marker Score: 5705
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 1.37
    Marker Score: 1844.5
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.35
    Marker Score: 10384
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.31
    Marker Score: 2022
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.26
    Marker Score: 19693
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 1.26
    Marker Score: 4326
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.25
    Marker Score: 18688
  • Cell Name: Unknown (CL0002371)
    Fold Change: 1.25
    Marker Score: 1323
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 1.21
    Marker Score: 707
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 1.21
    Marker Score: 707
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.19
    Marker Score: 25416
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.15
    Marker Score: 4267
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 1.13
    Marker Score: 486
  • Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
    Fold Change: 1.1
    Marker Score: 3196
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 1.08
    Marker Score: 3404
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 1.06
    Marker Score: 710
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.06
    Marker Score: 1144.5
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.05
    Marker Score: 1107
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 1.04
    Marker Score: 1120
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 1.02
    Marker Score: 294
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71696
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47920
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.98
    Marker Score: 335
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 0.98
    Marker Score: 411
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30391
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.97
    Marker Score: 284
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.97
    Marker Score: 9728
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.94
    Marker Score: 2397
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 0.94
    Marker Score: 4347
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 0.94
    Marker Score: 1344
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 0.93
    Marker Score: 523
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.93
    Marker Score: 1053
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.93
    Marker Score: 479
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 0.92
    Marker Score: 1155
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.92
    Marker Score: 435
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.9
    Marker Score: 2578
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.9
    Marker Score: 2704
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.9
    Marker Score: 613
  • Cell Name: oocyte (CL0000023)
    Fold Change: 0.89
    Marker Score: 221
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 0.89
    Marker Score: 1023
  • Cell Name: type A enteroendocrine cell (CL0002067)
    Fold Change: 0.89
    Marker Score: 358
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.88
    Marker Score: 737
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.88
    Marker Score: 1057.5
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: 0.88
    Marker Score: 7606
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5294
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 0.87
    Marker Score: 7474
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.86
    Marker Score: 311
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.86
    Marker Score: 5108.5
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 0.86
    Marker Score: 3062
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.85
    Marker Score: 7490
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.85
    Marker Score: 494
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.84
    Marker Score: 4806
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.83
    Marker Score: 263.5
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 0.82
    Marker Score: 1585
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.82
    Marker Score: 9188
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.81
    Marker Score: 28205
  • Cell Name: mucosal invariant T cell (CL0000940)
    Fold Change: 0.81
    Marker Score: 722
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 0.81
    Marker Score: 6029
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.8
    Marker Score: 259
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.8
    Marker Score: 296
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 0.8
    Marker Score: 1104
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 0.8
    Marker Score: 17847
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.79
    Marker Score: 476
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.79
    Marker Score: 317
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.79
    Marker Score: 725
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.79
    Marker Score: 398
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 0.78
    Marker Score: 222
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.78
    Marker Score: 598.5
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1263
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.77
    Marker Score: 3248
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.77
    Marker Score: 5002
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 0.77
    Marker Score: 1258.5
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: 0.76
    Marker Score: 1861.5
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 0.75
    Marker Score: 931
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 0.75
    Marker Score: 2051
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.75
    Marker Score: 652
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 0.75
    Marker Score: 1263
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.75
    Marker Score: 288
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.75
    Marker Score: 447
  • Cell Name: epithelial cell of glomerular capsule (CL1000450)
    Fold Change: 0.74
    Marker Score: 190
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.74
    Marker Score: 4442
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: 0.74
    Marker Score: 954
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.73
    Marker Score: 535

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Other Information

**Key characteristics:** * GTF3C1 is a protein of the TGF-beta superfamily. * It is a key regulator of the development and function of the nervous system. * It is involved in the regulation of a variety of cellular processes, including cell cycle regulation, proliferation, differentiation, and survival. **Pathways and functions:** GTF3C1 plays a role in a variety of cellular processes, including: * **Cell cycle regulation:** GTF3C1 is required for the initiation of cell cycle progression in proliferating cells. * **Proliferation:** GTF3C1 is essential for the proliferation of epithelial cells, including those in the skin, lung, and kidney. * **Differentiation:** GTF3C1 is required for the differentiation of neural cells from pluripotent stem cells. * **Survival:** GTF3C1 is essential for the survival of neurons. **Clinical significance:** Mutations in GTF3C1 have been linked to a number of human diseases, including: * **Neurological disorders:** Mutations in GTF3C1 have been linked to a number of neurological disorders, including autism, schizophrenia, and epilepsy. * **Cancer:** Mutations in GTF3C1 have also been linked to cancer. GTF3C1 is a promising target for the treatment of neurodegenerative diseases.

Genular Protein ID: 485202672

Symbol: TF3C1_HUMAN

Name: General transcription factor 3C polypeptide 1

UniProtKB Accession Codes:

Q12789 B2RP21 Q12838 Q6DKN9 Q9Y4W9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 EMDB 4 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 13 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 6 PDBsum 4 PIR 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 3 RefSeq 2 SAM 1 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8127861

Title: Human transcription factor IIIC box B binding subunit.

PubMed ID: 8127861

DOI: 10.1073/pnas.91.5.1652

PubMed ID: 10493829

Title: Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.

PubMed ID: 10493829

DOI: 10.1006/geno.1999.5927

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8164661

Title: Cloning and characterization of an evolutionarily divergent DNA-binding subunit of mammalian TFIIIC.

PubMed ID: 8164661

DOI: 10.1128/mcb.14.5.3053-3064.1994

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18377933

Title: Regulation of RNA polymerase III transcription by Maf1 in mammalian cells.

PubMed ID: 18377933

DOI: 10.1016/j.jmb.2008.02.060

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19299493

Title: Biochemical and genetic evidence for a role of IGHMBP2 in the translational machinery.

PubMed ID: 19299493

DOI: 10.1093/hmg/ddp134

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

  • Length: 2109
  • Mass: 238875
  • Checksum: 37A03135EFE695FC
  • Sequence:
    • MDALESLLDE VALEGLDGLC LPALWSRLET RVPPFPLPLE PCTQEFLWRA LATHPGISFY 
EEPRERPDLQ LQDRYEEIDL ETGILESRRD PVALEDVYPI HMILENKDGI QGSCRYFKER 
KNITNDIRTK SLQPRCTMVE AFDRWGKKLI IVASQAMRYR ALIGQEGDPD LKLPDFSYCI 
LERLGRSRWQ GELQRDLHTT AFKVDAGKLH YHRKILNKNG LITMQSHVIR LPTGAQQHSI 
LLLLNRFHVD RRSKYDILME KLSVMLSTRT NHIETLGKLR EELGLCERTF KRLYQYMLNA 
GLAKVVSLRL QEIHPECGPC KTKKGTDVMV RCLKLLKEFK RNDHDDDEDE EVISKTVPPV 
DIVFERDMLT QTYDLIERRG TKGISQAEIR VAMNVGKLEA RMLCRLLQRF KVVKGFMEDE 
GRQRTTKYIS CVFAEESDLS RQYQREKARS ELLTTVSLAS MQEESLLPEG EDTFLSESDS 
EEERSSSKRR GRGSQKDTRA SANLRPKTQP HHSTPTKGGW KVVNLHPLKK QPPSFPGAAE 
ERACQSLASR DSLLDTSSVS EPNVSFVSHC ADSNSGDIAV IEEVRMENPK ESSSSLKTGR 
HSSGQDKPHE TYRLLKRRNL IIEAVTNLRL IESLFTIQKM IMDQEKQEGV STKCCKKSIV 
RLVRNLSEEG LLRLYRTTVI QDGIKKKVDL VVHPSMDQND PLVRSAIEQV RFRISNSSTA 
NRVKTSQPPV PQGEAEEDSQ GKEGPSGSGD SQLSASSRSE SGRMKKSDNK MGITPLRNYH 
PIVVPGLGRS LGFLPKMPRL RVVHMFLWYL IYGHPASNTV EKPSFISERR TIKQESGRAG 
VRPSSSGSAW EACSEAPSKG SQDGVTWEAE VELATETVYV DDASWMRYIP PIPVHRDFGF 
GWALVSDILL CLPLSIFIQI VQVSYKVDNL EEFLNDPLKK HTLIRFLPRP IRQQLLYKRR 
YIFSVVENLQ RLCYMGLLQF GPTEKFQDKD QVFIFLKKNA VIVDTTICDP HYNLARSSRP 
FERRLYVLNS MQDVENYWFD LQCVCLNTPL GVVRCPRVRK NSSTDQGSDE EGSLQKEQES 
AMDKHNLERK CAMLEYTTGS REVVDEGLIP GDGLGAAGLD SSFYGHLKRN WIWTSYIINQ 
AKKENTAAEN GLTVRLQTFL SKRPMPLSAR GNSRLNIWGE ARVGSELCAG WEEQFEVDRE 
PSLDRNRRVR GGKSQKRKRL KKDPGKKIKR KKKGEFPGEK SKRLRYHDEA DQSALQRMTR 
LRVTWSMQED GLLVLCRIAS NVLNTKVKGP FVTWQVVRDI LHATFEESLD KTSHSVGRRA 
RYIVKNPQAY LNYKVCLAEV YQDKALVGDF MNRRGDYDDP KVCANEFKEF VEKLKEKFSS 
ALRNSNLEIP DTLQELFARY RVLAIGDEKD QTRKEDELNS VDDIHFLVLQ NLIQSTLALS 
DSQMKSYQSF QTFRLYREYK DHVLVKAFME CQKRSLVNRR RVNHTLGPKK NRALPFVPMS 
YQLSQTYYRI FTWRFPSTIC TESFQFLDRM RAAGKLDQPD RFSFKDQDNN EPTNDMVAFS 
LDGPGGNCVA VLTLFSLGLI SVDVRIPEQI IVVDSSMVEN EVIKSLGKDG SLEDDEDEED 
DLDEGVGGKR RSMEVKPAQA SHTNYLLMRG YYSPGIVSTR NLNPNDSIVV NSCQMKFQLR 
CTPVPARLRP AAAPLEELTM GTSCLPDTFT KLINPQENTC SLEEFVLQLE LSGYSPEDLT 
AALEILEAII ATGCFGIDKE ELRRRFSALE KAGGGRTRTF ADCIQALLEQ HQVLEVGGNT 
ARLVAMGSAW PWLLHSVRLK DREDADIQRE DPQARPLEGS SSEDSPPEGQ APPSHSPRGT 
KRRASWASEN GETDAEGTQM TPAKRPALQD SNLAPSLGPG AEDGAEAQAP SPPPALEDTA 
AAGAAQEDQE GVGEFSSPGQ EQLSGQAQPP EGSEDPRGFT ESFGAANISQ AARERDCESV 
CFIGRPWRVV DGHLNLPVCK GMMEAMLYHI MTRPGIPESS LLRHYQGVLQ PVAVLELLQG 
LESLGCIRKR WLRKPRPVSL FSTPVVEEVE VPSSLDESPM AFYEPTLDCT LRLGRVFPHE 
VNWNKWIHL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.