Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 209.0067
Cell Significance Index: -32.5100 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 134.6871
Cell Significance Index: -34.1600 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 82.5951
Cell Significance Index: -39.0000 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 79.4078
Cell Significance Index: -32.2600 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 70.5502
Cell Significance Index: -36.2900 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 58.0383
Cell Significance Index: -38.9500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 34.1034
Cell Significance Index: -32.5600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 29.3766
Cell Significance Index: -36.2200 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 12.9607
Cell Significance Index: -34.7200 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 9.4398
Cell Significance Index: -37.2500 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 8.6860
Cell Significance Index: -19.0100 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 8.6050
Cell Significance Index: -26.4300 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 2.4711
Cell Significance Index: 170.8900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.3881
Cell Significance Index: 106.5200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.1976
Cell Significance Index: 130.2700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.9952
Cell Significance Index: 197.5000 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.9222
Cell Significance Index: 59.5000 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.9127
Cell Significance Index: 10.8800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.8211
Cell Significance Index: 164.7100 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.8155
Cell Significance Index: 132.6400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.7039
Cell Significance Index: 126.8900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.6961
Cell Significance Index: 85.5900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.5496
Cell Significance Index: 34.6400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.4694
Cell Significance Index: 10.1700 - Cell Name: germ cell (CL0000586)
Fold Change: 0.4642
Cell Significance Index: 3.5100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.4634
Cell Significance Index: 63.6400 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.4596
Cell Significance Index: 6.2700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.4573
Cell Significance Index: 25.6600 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.3965
Cell Significance Index: 11.4300 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3891
Cell Significance Index: 212.5100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.3531
Cell Significance Index: 126.6500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.2815
Cell Significance Index: 124.4600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.2657
Cell Significance Index: 12.3900 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.2386
Cell Significance Index: 12.4300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1920
Cell Significance Index: 132.7900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1888
Cell Significance Index: 18.6700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.1589
Cell Significance Index: 18.7400 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1553
Cell Significance Index: 7.0400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.1352
Cell Significance Index: 6.3500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.1333
Cell Significance Index: 3.5600 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.1225
Cell Significance Index: 3.3400 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0840
Cell Significance Index: 5.9400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0781
Cell Significance Index: 146.9700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0688
Cell Significance Index: 11.7400 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0572
Cell Significance Index: 2.0100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0554
Cell Significance Index: 10.5500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.0444
Cell Significance Index: 1.2400 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0390
Cell Significance Index: 5.0000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0386
Cell Significance Index: 71.1200 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.0364
Cell Significance Index: 0.7100 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.0323
Cell Significance Index: 1.6800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0310
Cell Significance Index: 47.6800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0220
Cell Significance Index: 29.9400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0201
Cell Significance Index: 12.7500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.0185
Cell Significance Index: 16.7100 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.0153
Cell Significance Index: 0.4100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0036
Cell Significance Index: 1.6500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0076
Cell Significance Index: -5.6300 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0109
Cell Significance Index: -0.5700 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0116
Cell Significance Index: -8.4700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0116
Cell Significance Index: -7.2700 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.0193
Cell Significance Index: -0.6700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0319
Cell Significance Index: -24.1200 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0396
Cell Significance Index: -5.1100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0415
Cell Significance Index: -23.4000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0695
Cell Significance Index: -4.2700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0891
Cell Significance Index: -9.1000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0974
Cell Significance Index: -20.5100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1045
Cell Significance Index: -30.0600 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1162
Cell Significance Index: -2.4100 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.1235
Cell Significance Index: -14.1000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1284
Cell Significance Index: -18.6600 - Cell Name: decidual cell (CL2000002)
Fold Change: -0.1387
Cell Significance Index: -2.2300 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1515
Cell Significance Index: -10.1900 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.1592
Cell Significance Index: -2.3500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1823
Cell Significance Index: -21.2500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1938
Cell Significance Index: -22.2000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2064
Cell Significance Index: -15.3800 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.2148
Cell Significance Index: -3.9700 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.2353
Cell Significance Index: -3.5300 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.2373
Cell Significance Index: -6.2400 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2732
Cell Significance Index: -28.4500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.2817
Cell Significance Index: -12.4600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3072
Cell Significance Index: -9.8400 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.3437
Cell Significance Index: -9.2000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.3440
Cell Significance Index: -8.6000 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.3551
Cell Significance Index: -13.4500 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.3645
Cell Significance Index: -9.3700 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.3765
Cell Significance Index: -7.8800 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.3767
Cell Significance Index: -6.3100 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.3833
Cell Significance Index: -3.5300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3894
Cell Significance Index: -30.8400 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.3924
Cell Significance Index: -19.8300 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.3939
Cell Significance Index: -11.2900 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.4394
Cell Significance Index: -26.9400 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.4603
Cell Significance Index: -4.7600 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.4777
Cell Significance Index: -14.0300 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.5468
Cell Significance Index: -13.9700 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: -0.5603
Cell Significance Index: -8.5100 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.5724
Cell Significance Index: -9.8100
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 376410084
Symbol: UBN1_HUMAN
Name: Ubinuclein-1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10725330
Title: Ubinuclein, a novel nuclear protein interacting with cellular and viral transcription factors.
PubMed ID: 10725330
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15616553
Title: The sequence and analysis of duplication-rich human chromosome 16.
PubMed ID: 15616553
DOI: 10.1038/nature03187
PubMed ID: 14718166
Title: Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis.
PubMed ID: 14718166
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18823282
Title: Characterization of the ubinuclein protein as a new member of the nuclear and adhesion complex components (NACos).
PubMed ID: 18823282
DOI: 10.1042/bc20080072
PubMed ID: 19029251
Title: Human UBN1 is an ortholog of yeast Hpc2p and has an essential role in the HIRA/ASF1a chromatin-remodeling pathway in senescent cells.
PubMed ID: 19029251
DOI: 10.1128/mcb.01047-08
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 1134
- Mass: 121520
- Checksum: 8DE68C63D4E8E01B
- Sequence:
MSEPHRVQFT SLPGSLNPAF LKKSRKEEAG AGEQHQDCEP AAAAVRITLT LFEPDHKRCP EFFYPELVKN IRGKVKGLQP GDKKKDLSDP FNDEEKERHK VEALARKFEE KYGGKKRRKD RIQDLIDMGY GYDESDSFID NSEAYDELVP ASLTTKYGGF YINSGTLQFR QASESEDDFI KEKKKKSPKK RKLKEGGEKI KKKKKDDTYD KEKKSKKSKF SKAGFTALNA SKEKKKKKYS GALSVKEMLK KFQKEKEAQK KREEEHKPVA VPSAEAQGLR ELEGASDPLL SLFGSTSDND LLQAATAMDS LTDLDLEHLL SESPEGSPFR DMDDGSDSLG VGLDQEFRQP SSLPEGLPAP LEKRVKELAQ AARAAEGESR QKFFTQDING ILLDIEAQTR ELSSQVRSGV YAYLASFLPC SKDALLKRAR KLHLYEQGGR LKEPLQKLKE AIGRAMPEQM AKYQDECQAH TQAKVAKMLE EEKDKEQRDR ICSDEEEDEE KGGRRIMGPR KKFQWNDEIR ELLCQVVKIK LESQDLERNN KAQAWEDCVK GFLDAEVKPL WPKGWMQART LFKESRRGHG HLTSILAKKK VMAPSKIKVK ESSTKPDKKV SVPSGQIGGP IALPSDHQTG GLSIGASSRE LPSQASGGLA NPPPVNLEDS LDEDLIRNPA SSVEAVSKEL AALNSRAAGN SEFTLPAPSK APAEKVGGVL CTEEKRNFAK PSPSAPPPAS SLQSPLNFLA EQALALGQSS QEKKPESSGY KELSCQAPLN KGLPEVHQSK AKHHSLPRTS HGPQVAVPVP GPQVKVFHAG TQQQKNFTPP SPFANKLQGP KASPTQCHRS LLQLVKTAAK GQGFHPSAPA TSGGLSASSS SSHKTPASSS SALSHPAKPH SVSSAGSSYK NNPFASSISK HGVSSGSSSS GGTPVQSSVS GSLVPGIQPP SVGQATSRPV PSSAGKKMPV SQKLTLVAPP GGPNGDSSGG TQGVAKLLTS PSLKPSAVSS VTSSTSLSKG ASGTVLLAGS SLMASPYKSS SPKLSGAMSS NSLGIITPVP IPVHVLSFSA DSSAKAGVSK DAIVTGPAPG SFHHGLGHSL LAGLHSSPPH AAPLPHAAVP THIPQSLPGA SQLHGKGPAV PRKL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.