Details for: EEF2K

Gene ID: 29904

Symbol: EEF2K

Ensembl ID: ENSG00000103319

Description: eukaryotic elongation factor 2 kinase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 200.1990
    Cell Significance Index: -31.1400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 123.4410
    Cell Significance Index: -31.3100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 63.4327
    Cell Significance Index: -25.7700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 27.0492
    Cell Significance Index: -25.8300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 25.9539
    Cell Significance Index: -32.0000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 11.3369
    Cell Significance Index: -30.3700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 8.5562
    Cell Significance Index: -26.2800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 8.4027
    Cell Significance Index: -18.3900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.2196
    Cell Significance Index: -32.4400
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 2.7850
    Cell Significance Index: 18.8700
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 2.4694
    Cell Significance Index: 61.5800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 2.1180
    Cell Significance Index: 59.1900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.6427
    Cell Significance Index: 32.0600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.2321
    Cell Significance Index: 121.8800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.9743
    Cell Significance Index: 195.4400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7785
    Cell Significance Index: 154.5000
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 0.6920
    Cell Significance Index: 1.5600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.6725
    Cell Significance Index: 14.5700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6559
    Cell Significance Index: 106.6800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.5832
    Cell Significance Index: 44.7600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5747
    Cell Significance Index: 62.5100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.5626
    Cell Significance Index: 12.0300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.5558
    Cell Significance Index: 384.3900
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 0.5462
    Cell Significance Index: 4.2100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.4050
    Cell Significance Index: 20.4700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.4012
    Cell Significance Index: 8.7900
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.3664
    Cell Significance Index: 8.9400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.3425
    Cell Significance Index: 15.9700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3094
    Cell Significance Index: 136.8100
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 0.2894
    Cell Significance Index: 4.0700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2769
    Cell Significance Index: 49.9300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2580
    Cell Significance Index: 17.8400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2573
    Cell Significance Index: 92.2900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2515
    Cell Significance Index: 473.4700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2454
    Cell Significance Index: 46.7000
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: 0.2101
    Cell Significance Index: 3.3900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2058
    Cell Significance Index: 25.3100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1976
    Cell Significance Index: 4.9400
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.1849
    Cell Significance Index: 2.7700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1424
    Cell Significance Index: 2.4400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1393
    Cell Significance Index: 76.0500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1315
    Cell Significance Index: 3.7900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1164
    Cell Significance Index: 158.3300
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1046
    Cell Significance Index: 7.4000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0838
    Cell Significance Index: 53.2200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0604
    Cell Significance Index: 8.3000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0562
    Cell Significance Index: 86.5500
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 0.0556
    Cell Significance Index: 0.7000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0472
    Cell Significance Index: 87.0300
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.0286
    Cell Significance Index: 0.4100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0137
    Cell Significance Index: 0.6200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0036
    Cell Significance Index: -0.2000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0040
    Cell Significance Index: -0.2100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0119
    Cell Significance Index: -5.3900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0330
    Cell Significance Index: -1.7200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0345
    Cell Significance Index: -25.3300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0351
    Cell Significance Index: -2.2100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0365
    Cell Significance Index: -27.6400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0371
    Cell Significance Index: -2.4000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0373
    Cell Significance Index: -5.4200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0421
    Cell Significance Index: -31.1800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0444
    Cell Significance Index: -1.5600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0480
    Cell Significance Index: -8.1900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0569
    Cell Significance Index: -2.5200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0570
    Cell Significance Index: -32.1300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0610
    Cell Significance Index: -38.1100
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0664
    Cell Significance Index: -0.9800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0936
    Cell Significance Index: -26.9200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0969
    Cell Significance Index: -3.6700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1201
    Cell Significance Index: -12.2700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1435
    Cell Significance Index: -18.5500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1501
    Cell Significance Index: -17.7000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1536
    Cell Significance Index: -19.6900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1598
    Cell Significance Index: -18.6200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1697
    Cell Significance Index: -35.7500
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1870
    Cell Significance Index: -4.3200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2038
    Cell Significance Index: -23.3500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2060
    Cell Significance Index: -5.5000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2151
    Cell Significance Index: -10.1100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2196
    Cell Significance Index: -4.6600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2343
    Cell Significance Index: -4.9900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2628
    Cell Significance Index: -27.3600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2694
    Cell Significance Index: -20.0800
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: -0.2805
    Cell Significance Index: -2.4900
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: -0.3031
    Cell Significance Index: -1.8700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.3284
    Cell Significance Index: -8.9400
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.3383
    Cell Significance Index: -5.8500
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.3414
    Cell Significance Index: -5.0400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3434
    Cell Significance Index: -27.2000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3490
    Cell Significance Index: -7.2400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3669
    Cell Significance Index: -9.4300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3737
    Cell Significance Index: -11.9700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3861
    Cell Significance Index: -20.2700
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.3961
    Cell Significance Index: -3.2300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4094
    Cell Significance Index: -4.8800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.4572
    Cell Significance Index: -12.2500
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.4602
    Cell Significance Index: -9.1000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.4705
    Cell Significance Index: -6.4200
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.4905
    Cell Significance Index: -7.0300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5146
    Cell Significance Index: -31.5500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **EF2K structure and function:** EEF2K is a serine/threonine kinase that phosphorylates and activates eukaryotic elongation factor 2 (eEF2), a translation initiation factor. This phosphorylation event regulates protein synthesis and elongation. 2. **Cellular localization:** EEF2K is predominantly found in the cytosol and nucleus, with specific expression in neurons, muscle cells, and epithelial cells. 3. **Expression patterns:** EEF2K is highly expressed in neurons, particularly in the cerebral cortex, and in muscle cells, including skeletal muscle fibers. 4. **Regulatory mechanisms:** EEF2K is regulated by various signaling pathways, including calmodulin, calcium ion binding, and insulin stimulus. **Pathways and Functions:** 1. **Translation regulation:** EEF2K phosphorylates eEF2, regulating protein synthesis and elongation. This process is crucial for maintaining cellular homeostasis and responding to environmental changes. 2. **Signaling pathways:** EEF2K is involved in various signaling pathways, including: * mTORC1-mediated signaling: Regulates protein synthesis and autophagy. * Calcium ion binding: Regulates muscle contraction and relaxation. * Calmodulin binding: Regulates muscle contraction and cellular responses to anoxia. * Insulin stimulus: Regulates glucose metabolism and protein synthesis. 3. **Autophagy and apoptosis:** EEF2K regulates autophagy and apoptosis by modulating protein synthesis and translation. 4. **Dendritic spine morphogenesis:** EEF2K promotes dendritic spine morphogenesis, a process critical for synaptic plasticity and learning. **Clinical Significance:** 1. **Neurological disorders:** EEF2K dysregulation has been implicated in various neurological disorders, including Alzheimer's disease, Parkinson's disease, and stroke. 2. **Muscular dystrophy:** Mutations in EEF2K have been associated with muscular dystrophy, highlighting its role in muscle cell function and survival. 3. **Cancer:** EEF2K dysregulation has been linked to cancer progression, suggesting its potential as a therapeutic target. 4. **Ischemia and stroke:** EEF2K plays a critical role in responding to ischemia and stroke, highlighting its potential as a therapeutic target for treating these conditions. In conclusion, EEF2K is a multifunctional gene that regulates various cellular processes, including translation, signaling, and autophagy. Its dysregulation has been implicated in various diseases, highlighting its potential as a therapeutic target. Further research is necessary to fully elucidate the mechanisms of EEF2K and its role in human disease.

Genular Protein ID: 2522327892

Symbol: EF2K_HUMAN

Name: Eukaryotic elongation factor 2 kinase

UniProtKB Accession Codes:

O00418 Q8N588

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 2 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 6 ChEMBL 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 ELM 1 EMBL 3 Ensembl 1 ExpressionAtlas 1 GO 27 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 8 PIRSF 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 3 Rhea 3 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9144159

Title: Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase.

PubMed ID: 9144159

DOI: 10.1073/pnas.94.10.4884

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11015200

Title: Mapping the functional domains of elongation factor-2 kinase.

PubMed ID: 11015200

DOI: 10.1021/bi0007270

PubMed ID: 11500363

Title: A novel method to identify protein kinase substrates: eEF2 kinase is phosphorylated and inhibited by SAPK4/p38delta.

PubMed ID: 11500363

DOI: 10.1093/emboj/20.16.4360

PubMed ID: 11500364

Title: Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.

PubMed ID: 11500364

DOI: 10.1093/emboj/20.16.4370

PubMed ID: 15144186

Title: Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

PubMed ID: 15144186

DOI: 10.1021/ac035352d

PubMed ID: 14709557

Title: Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its phosphorylation at a novel site, serine 398.

PubMed ID: 14709557

DOI: 10.1074/jbc.m309773200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 18337751

Title: cdc2-cyclin B regulates eEF2 kinase activity in a cell cycle- and amino acid-dependent manner.

PubMed ID: 18337751

DOI: 10.1038/emboj.2008.39

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21112387

Title: The channel-kinase TRPM7 regulates phosphorylation of the translational factor eEF2 via eEF2-k.

PubMed ID: 21112387

DOI: 10.1016/j.cellsig.2010.11.011

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22216903

Title: Identification of autophosphorylation sites in eukaryotic elongation factor-2 kinase.

PubMed ID: 22216903

DOI: 10.1042/bj20111530

PubMed ID: 22223895

Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.

PubMed ID: 22223895

DOI: 10.1074/mcp.m111.015131

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 725
  • Mass: 82144
  • Checksum: 9D2900E50EFF12DA
  • Sequence:
    • MADEDLIFRL EGVDGGQSPR AGHDGDSDGD SDDEEGYFIC PITDDPSSNQ NVNSKVNKYY 
SNLTKSERYS SSGSPANSFH FKEAWKHAIQ KAKHMPDPWA EFHLEDIATE RATRHRYNAV 
TGEWLDDEVL IKMASQPFGR GAMRECFRTK KLSNFLHAQQ WKGASNYVAK RYIEPVDRDV 
YFEDVRLQME AKLWGEEYNR HKPPKQVDIM QMCIIELKDR PGKPLFHLEH YIEGKYIKYN 
SNSGFVRDDN IRLTPQAFSH FTFERSGHQL IVVDIQGVGD LYTDPQIHTE TGTDFGDGNL 
GVRGMALFFY SHACNRICES MGLAPFDLSP RERDAVNQNT KLLQSAKTIL RGTEEKCGSP 
QVRTLSGSRP PLLRPLSENS GDENMSDVTF DSLPSSPSSA TPHSQKLDHL HWPVFSDLDN 
MASRDHDHLD NHRESENSGD SGYPSEKRGE LDDPEPREHG HSYSNRKYES DEDSLGSSGR 
VCVEKWNLLN SSRLHLPRAS AVALEVQRLN ALDLEKKIGK SILGKVHLAM VRYHEGGRFC 
EKGEEWDQES AVFHLEHAAN LGELEAIVGL GLMYSQLPHH ILADVSLKET EENKTKGFDY 
LLKAAEAGDR QSMILVARAF DSGQNLSPDR CQDWLEALHW YNTALEMTDC DEGGEYDGMQ 
DEPRYMMLAR EAEMLFTGGY GLEKDPQRSG DLYTQAAEAA MEAMKGRLAN QYYQKAEEAW 
AQMEE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.