Details for: LRP12
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 168.6969
Cell Significance Index: -26.2400 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 100.8108
Cell Significance Index: -25.5700 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 60.4689
Cell Significance Index: -24.9100 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 56.2354
Cell Significance Index: -26.5500 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 53.5375
Cell Significance Index: -21.7500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 22.7915
Cell Significance Index: -21.7600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 21.3309
Cell Significance Index: -26.3000 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 9.8213
Cell Significance Index: -26.3100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 6.6978
Cell Significance Index: -26.4300 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: 3.9442
Cell Significance Index: 65.0000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 2.3643
Cell Significance Index: 104.5800 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 2.1194
Cell Significance Index: 60.4800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 1.9339
Cell Significance Index: 73.2300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.8184
Cell Significance Index: 364.7600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 1.3885
Cell Significance Index: 93.3600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.0288
Cell Significance Index: 369.0100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.9623
Cell Significance Index: 95.1900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.9158
Cell Significance Index: 51.3900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.8685
Cell Significance Index: 66.6500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.7082
Cell Significance Index: 639.4900 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.6895
Cell Significance Index: 14.6900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.6127
Cell Significance Index: 423.8000 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.6063
Cell Significance Index: 16.2500 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.5984
Cell Significance Index: 36.7800 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.5299
Cell Significance Index: 15.1900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.5027
Cell Significance Index: 81.7600 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.4568
Cell Significance Index: 10.9600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.4559
Cell Significance Index: 49.5900 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.4384
Cell Significance Index: 5.4400 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.3621
Cell Significance Index: 4.9400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.3461
Cell Significance Index: 20.7800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.3209
Cell Significance Index: 8.0200 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.2877
Cell Significance Index: 4.6200 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.2699
Cell Significance Index: 119.3200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.2071
Cell Significance Index: 28.4400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1718
Cell Significance Index: 11.8800 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.1513
Cell Significance Index: 3.8900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.1284
Cell Significance Index: 2.2000 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1084
Cell Significance Index: 19.5400 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0870
Cell Significance Index: 47.4900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0814
Cell Significance Index: 15.5000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0791
Cell Significance Index: 3.6900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0717
Cell Significance Index: 3.2500 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0477
Cell Significance Index: 1.3800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0320
Cell Significance Index: 2.2600 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0159
Cell Significance Index: 7.2000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.0125
Cell Significance Index: 1.4600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0108
Cell Significance Index: 2.1500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0054
Cell Significance Index: 10.2000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0026
Cell Significance Index: 1.6400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0014
Cell Significance Index: 2.1600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0042
Cell Significance Index: -7.7600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0089
Cell Significance Index: -12.1600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0106
Cell Significance Index: -1.3000 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: -0.0235
Cell Significance Index: -0.1800 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0240
Cell Significance Index: -17.6100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0255
Cell Significance Index: -18.8900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0267
Cell Significance Index: -1.6800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0299
Cell Significance Index: -4.3500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0326
Cell Significance Index: -24.6900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0397
Cell Significance Index: -1.4000 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0426
Cell Significance Index: -24.0200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0458
Cell Significance Index: -28.5700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0469
Cell Significance Index: -1.3100 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0649
Cell Significance Index: -1.4200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0669
Cell Significance Index: -1.4500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0736
Cell Significance Index: -12.5700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0754
Cell Significance Index: -21.7000 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0860
Cell Significance Index: -11.0300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0901
Cell Significance Index: -4.6800 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.0902
Cell Significance Index: -2.2000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1225
Cell Significance Index: -6.4300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1271
Cell Significance Index: -7.7900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1300
Cell Significance Index: -27.3800 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.1393
Cell Significance Index: -4.5600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1572
Cell Significance Index: -16.0600 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1701
Cell Significance Index: -21.9700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1893
Cell Significance Index: -21.6900 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.2110
Cell Significance Index: -6.7200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.2244
Cell Significance Index: -26.4600 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.2277
Cell Significance Index: -3.8100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2293
Cell Significance Index: -23.8800 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -0.2649
Cell Significance Index: -2.5200 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.2818
Cell Significance Index: -4.1600 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.2862
Cell Significance Index: -7.7900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3074
Cell Significance Index: -24.3500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.3092
Cell Significance Index: -14.5300 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.3125
Cell Significance Index: -6.1800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.3150
Cell Significance Index: -23.4800 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.3439
Cell Significance Index: -7.3000 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.3463
Cell Significance Index: -18.0400 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.3631
Cell Significance Index: -7.2900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.3797
Cell Significance Index: -24.5000 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.3892
Cell Significance Index: -8.3200 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.3922
Cell Significance Index: -13.6300 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.4053
Cell Significance Index: -7.9100 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.4300
Cell Significance Index: -9.2900 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.4565
Cell Significance Index: -6.0900 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.4567
Cell Significance Index: -16.0000 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.4723
Cell Significance Index: -12.4200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2736649081
Symbol: LRP12_HUMAN
Name: Low-density lipoprotein receptor-related protein 12
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9927190
Title: Cloning and characterization of a novel gene encoding a putative transmembrane protein with altered expression in some human transformed and tumor-derived cell lines.
PubMed ID: 9927190
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16421571
Title: DNA sequence and analysis of human chromosome 8.
PubMed ID: 16421571
DOI: 10.1038/nature04406
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12809483
Title: ST7 is a novel low-density lipoprotein receptor-related protein (LRP) with a cytoplasmic tail that interacts with proteins related to signal transduction pathways.
PubMed ID: 12809483
DOI: 10.1021/bi034081y
PubMed ID: 31332380
Title: Noncoding CGG repeat expansions in neuronal intranuclear inclusion disease, oculopharyngodistal myopathy and an overlapping disease.
PubMed ID: 31332380
PubMed ID: 37339631
Title: CGG repeat expansion in LRP12 in amyotrophic lateral sclerosis.
PubMed ID: 37339631
Sequence Information:
- Length: 859
- Mass: 94984
- Checksum: 41A8FD8121E32A92
- Sequence:
MACRWSTKES PRWRSALLLL FLAGVYGNGA LAEHSENVHI SGVSTACGET PEQIRAPSGI ITSPGWPSEY PAKINCSWFI RANPGEIITI SFQDFDIQGS RRCNLDWLTI ETYKNIESYR ACGSTIPPPY ISSQDHIWIR FHSDDNISRK GFRLAYFSGK SEEPNCACDQ FRCGNGKCIP EAWKCNNMDE CGDSSDEEIC AKEANPPTAA AFQPCAYNQF QCLSRFTKVY TCLPESLKCD GNIDCLDLGD EIDCDVPTCG QWLKYFYGTF NSPNYPDFYP PGSNCTWLID TGDHRKVILR FTDFKLDGTG YGDYVKIYDG LEENPHKLLR VLTAFDSHAP LTVVSSSGQI RVHFCADKVN AARGFNATYQ VDGFCLPWEI PCGGNWGCYT EQQRCDGYWH CPNGRDETNC TMCQKEEFPC SRNGVCYPRS DRCNYQNHCP NGSDEKNCFF CQPGNFHCKN NRCVFESWVC DSQDDCGDGS DEENCPVIVP TRVITAAVIG SLICGLLLVI ALGCTCKLYS LRMFERRSFE TQLSRVEAEL LRREAPPSYG QLIAQGLIPP VEDFPVCSPN QASVLENLRL AVRSQLGFTS VRLPMAGRSS NIWNRIFNFA RSRHSGSLAL VSADGDEVVP SQSTSREPER NHTHRSLFSV ESDDTDTENE RRDMAGASGG VAAPLPQKVP PTTAVEATVG ACASSSTQST RGGHADNGRD VTSVEPPSVS PARHQLTSAL SRMTQGLRWV RFTLGRSSSL SQNQSPLRQL DNGVSGREDD DDVEMLIPIS DGSSDFDVND CSRPLLDLAS DQGQGLRQPY NATNPGVRPS NRDGPCERCG IVHTAQIPDT CLEVTLKNET SDDEALLLC
Genular Protein ID: 609178045
Symbol: Q59H02_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 793
- Mass: 87909
- Checksum: E3B82E6D458917FA
- Sequence:
ACDYPAKINC SWFIRANPGE IITISFQDFD IQGSRRCNLD WLTIETYKNI ESYRACGSTI PPPYISSQDH IWIRFHSDDN ISRKGFRLAY FSGKSEEPNC ACDQFRCGNG KCIPEAWKCN NMDECGDSSD EEICAKEANP PTAAAFQPCA YNQFQCLSRF TKVYTCLPES LKCDGNIDCL DLGDEIDCDV PTCGQWLKYF YGTFNSPNYP DFYPPGSNCT WLIDTGDHRK VILRFTDFKL DGTGYGDYVK IYDGLEENPH KLLRVLTAFD SHAPLTVVSS SGQIRVHFCA DKVNAARGFN ATYQVDGFCL PWEIPCGGNW GCYTEQQRCD GYWHCPNGRD ETNCTMCQKE EFPCSRNGVC YPRSDRCNYQ NHCPNGSDEK NCFFCQPGNF HCKNNRCVFE SWVCDSQDDC GDGSDEENCP VIVPTRVITA AVIGSLICGL LLVIALGCTC KLYSLRMFER RSFETQLSRV EAELLRREAP PSYGQLIAQG LIPPVEDFPV CSPNQASVLE NLRLAVRSQL GFTSVRLPMA GRSSNIWNRI FNFARSRHSG SLALVSADGD EVVPSQSTSR EPERNHTHRS LFSVESDDTD TENERRDMAG ASGGVAAPLP QKVPPTTAVE ATVGACASSS TQSTRGGHAD NGRDVTSVEP PSVSPARHQL TSALSRMTQG LRWVRFTLGR SSSLSQNQSP LRQLDNGVSG REDDDDVEML IPISDGSSDF DVNDCSRPLL DLASDQGQGL RQPYNATNPG VRPSNRDGPC ERCGIVHTAQ IPDTCLEVTL KNETSDDEAL LLC
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.