Details for: APBB2

Gene ID: 323

Symbol: APBB2

Ensembl ID: ENSG00000163697

Description: amyloid beta precursor protein binding family B member 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 544.6647
    Cell Significance Index: -84.7200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 334.6036
    Cell Significance Index: -84.8700
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 206.7132
    Cell Significance Index: -85.1600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 172.5508
    Cell Significance Index: -70.1000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 73.5172
    Cell Significance Index: -70.1900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 68.6886
    Cell Significance Index: -84.6900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 36.1169
    Cell Significance Index: -79.0500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 23.2105
    Cell Significance Index: -71.2900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 21.4645
    Cell Significance Index: -84.7000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 5.8743
    Cell Significance Index: 114.6500
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 4.7613
    Cell Significance Index: 68.4800
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 4.6203
    Cell Significance Index: 98.7600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.7389
    Cell Significance Index: 543.5400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.5353
    Cell Significance Index: 508.5700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.4590
    Cell Significance Index: 882.0000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 2.2757
    Cell Significance Index: 433.0900
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 2.1537
    Cell Significance Index: 27.1200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.7445
    Cell Significance Index: 1206.5500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.5544
    Cell Significance Index: 104.5200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.2369
    Cell Significance Index: 46.8400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 1.0521
    Cell Significance Index: 26.3000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.0046
    Cell Significance Index: 44.4400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.8909
    Cell Significance Index: 49.9900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.8798
    Cell Significance Index: 794.4400
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 0.8270
    Cell Significance Index: 3.6000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.8029
    Cell Significance Index: 41.8200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.7396
    Cell Significance Index: 45.4600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.6903
    Cell Significance Index: 19.7000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5083
    Cell Significance Index: 50.2800
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.5081
    Cell Significance Index: 7.7300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.5071
    Cell Significance Index: 689.4900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.5031
    Cell Significance Index: 319.5500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.4597
    Cell Significance Index: 707.7000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.3932
    Cell Significance Index: 30.1800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3781
    Cell Significance Index: 61.5000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.3626
    Cell Significance Index: 668.6700
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.2987
    Cell Significance Index: 4.2900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2648
    Cell Significance Index: 498.5800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.2633
    Cell Significance Index: 119.5100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1493
    Cell Significance Index: 26.9100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1005
    Cell Significance Index: 10.9400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0565
    Cell Significance Index: 7.7700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0157
    Cell Significance Index: 0.5500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0064
    Cell Significance Index: 0.1800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0110
    Cell Significance Index: -6.0200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0240
    Cell Significance Index: -0.6400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0490
    Cell Significance Index: -21.6800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0568
    Cell Significance Index: -42.0700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0583
    Cell Significance Index: -8.4700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0922
    Cell Significance Index: -67.6200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1003
    Cell Significance Index: -62.6200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1143
    Cell Significance Index: -64.4400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.1175
    Cell Significance Index: -88.9500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1387
    Cell Significance Index: -17.0600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1412
    Cell Significance Index: -2.4200
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.1572
    Cell Significance Index: -0.9500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1645
    Cell Significance Index: -7.4600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2514
    Cell Significance Index: -52.9600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2574
    Cell Significance Index: -74.0500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.2594
    Cell Significance Index: -7.4800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.2739
    Cell Significance Index: -6.5700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.3068
    Cell Significance Index: -52.3900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.3234
    Cell Significance Index: -41.4600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.3381
    Cell Significance Index: -23.3800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3439
    Cell Significance Index: -35.8100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.4531
    Cell Significance Index: -27.2000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.5157
    Cell Significance Index: -52.6800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.5190
    Cell Significance Index: -11.2500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.5283
    Cell Significance Index: -62.3000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.5614
    Cell Significance Index: -65.4300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.5935
    Cell Significance Index: -76.6700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.6127
    Cell Significance Index: -70.2000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.6231
    Cell Significance Index: -71.1300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.6330
    Cell Significance Index: -13.8600
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.6568
    Cell Significance Index: -4.4500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.6831
    Cell Significance Index: -14.1700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.7679
    Cell Significance Index: -20.5800
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: -0.8192
    Cell Significance Index: -8.4900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.8198
    Cell Significance Index: -61.1000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.8405
    Cell Significance Index: -51.5300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.9520
    Cell Significance Index: -30.4900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.9854
    Cell Significance Index: -78.0500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.9943
    Cell Significance Index: -46.3600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -1.0043
    Cell Significance Index: -47.2000
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -1.0297
    Cell Significance Index: -12.8400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -1.0460
    Cell Significance Index: -73.9800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -1.0469
    Cell Significance Index: -67.5400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -1.0728
    Cell Significance Index: -22.7700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.1417
    Cell Significance Index: -71.9600
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -1.2274
    Cell Significance Index: -13.1600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.3512
    Cell Significance Index: -70.1900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -1.4064
    Cell Significance Index: -20.1400
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -1.4682
    Cell Significance Index: -18.5300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.4741
    Cell Significance Index: -37.8900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.4793
    Cell Significance Index: -77.6700
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -1.4861
    Cell Significance Index: -15.4800
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -1.5728
    Cell Significance Index: -31.1000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.5731
    Cell Significance Index: -50.1000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.6597
    Cell Significance Index: -54.3400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.6756
    Cell Significance Index: -58.7000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** APBB2 is a member of the amyloid beta precursor protein binding family and is characterized by its ability to interact with various proteins, including amyloid beta precursor protein, tau protein, and synaptophysin. This gene is expressed in a wide range of cell types, including contractile cells, oligodendrocytes, and cardiac neurons. APBB2 is also notable for its involvement in negative regulation of apoptosis, cell cycle phase transition, and transcription by RNA polymerase II. **Pathways and Functions:** APBB2 is involved in multiple signaling pathways, including: 1. **Amyloid-beta binding:** APBB2 interacts with amyloid beta precursor protein, modulating its processing and aggregation. 2. **Axon guidance:** APBB2 plays a crucial role in axon guidance, regulating the formation and maintenance of axonal projections. 3. **Intracellular signal transduction:** APBB2 is involved in various signaling pathways, including those regulating cell growth, differentiation, and survival. 4. **Transcription regulation:** APBB2 interacts with transcription factors, influencing the expression of genes involved in cellular processes. **Clinical Significance:** APBB2 has been implicated in various neurological and immunological disorders, including: 1. **Alzheimer's disease:** APBB2 has been shown to interact with amyloid beta, contributing to its aggregation and neurotoxicity. 2. **Neurodegenerative diseases:** APBB2 has been linked to other neurodegenerative diseases, such as frontotemporal dementia and amyotrophic lateral sclerosis. 3. **Immunological disorders:** APBB2 has been implicated in autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis. **Implications for Immunology and Neurobiology:** The study of APBB2 has significant implications for our understanding of immunological and neurological disorders. By elucidating the mechanisms by which APBB2 interacts with proteins and regulates cellular processes, researchers can gain insights into the development and progression of these diseases. Furthermore, the identification of APBB2 as a key player in axon guidance and intracellular signal transduction highlights its potential as a therapeutic target for neurological disorders. In conclusion, APBB2 is a complex gene that plays a multifaceted role in various cellular processes. Its involvement in amyloid-beta binding, axon guidance, and transcription regulation has significant implications for our understanding of immunological and neurological disorders. Further research is necessary to fully elucidate the functions of APBB2 and its potential as a therapeutic target.

Genular Protein ID: 1720800923

Symbol: APBB2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q92870 B4DSL4 E9PG87 Q8IUI6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 3 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 5 ExpressionAtlas 1 GO 23 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 RefSeq 9 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8855266

Title: Association of a novel human FE65-like protein with the cytoplasmic domain of the amyloid-beta precursor protein.

PubMed ID: 8855266

DOI: 10.1073/pnas.93.20.10832

PubMed ID: 14527950

Title: Generation of the beta-amyloid peptide and the amyloid precursor protein C-terminal fragment gamma are potentiated by FE65L1.

PubMed ID: 14527950

DOI: 10.1074/jbc.m309561200

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 758
  • Mass: 83374
  • Checksum: 453521022CD548D5
  • Sequence:
    • MSEVLPADSG VDTLAVFMAS SGTTDVTNRN SPATPPNTLN LRSSHNELLN AEIKHTETKN 
STPPKCRKKY ALTNIQAAMG LSDPAAQPLL GNGSANIKLV KNGENQLRKA AEQGQQDPNK 
NLSPTAVINI TSEKLEGKEP HPQDSSSCEI LPSQPRRTKS FLNYYADLET SARELEQNRG 
NHHGTAEEKS QPVQGQASTI IGNGDLLLQK PNRPQSSPED GQVATVSSSP ETKKDHPKTG 
AKTDCALHRI QNLAPSDEES SWTTLSQDSA SPSSPDETDI WSDHSFQTDP DLPPGWKRVS 
DIAGTYYWHI PTGTTQWERP VSIPADLQGS RKGSLSSVTP SPTPENEKQP WSDFAVLNGG 
KINSDIWKDL HAATVNPDPS LKEFEGATLR YASLKLRNAP HPDDDDSCSI NSDPEAKCFA 
VRSLGWVEMA EEDLAPGKSS VAVNNCIRQL SYCKNDIRDT VGIWGEGKDM YLILENDMLS 
LVDPMDRSVL HSQPIVSIRV WGVGRDNGRD FAYVARDKDT RILKCHVFRC DTPAKAIATS 
LHEICSKIMA ERKNAKALAC SSLQERANVN LDVPLQVDFP TPKTELVQKF HVQYLGMLPV 
DKPVGMDILN SAIENLMTSS NKEDWLSVNM NVADATVTVI SEKNEEEVLV ECRVRFLSFM 
GVGKDVHTFA FIMDTGNQRF ECHVFWCEPN AGNVSEAVQA ACMLRYQKCL VARPPSQKVR 
PPPPPADSVT RRVTTNVKRG VLSLIDTLKQ KRPVTEMP

Genular Protein ID: 4012541858

Symbol: G5E9Y1_HUMAN

Name: N/A

UniProtKB Accession Codes:

G5E9Y1

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 6 Ensembl 2 GO 1 Gene3D 2 GeneTree 1 HGNC 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 2 SAM 1 SMART 2 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 737
  • Mass: 80988
  • Checksum: 14DB64552C14B8F0
  • Sequence:
    • MSEVLPADSG VDTLAVFMAS SGTTDVTNRN SPATPPNTLN LRSSHNELLN AEIKHTETKN 
STPPKCRKKY ALTNIQAAMG LSDPAAQPLL GNGSANIKLV KNGENQLRKA AEQGQQDPNK 
NLSPTAVINI TSEKLEGKEP HPQDSSSCEI LPSQPRRTKS FLNYYADLET SARELEQNRG 
NHHGTAEEKS QPVQGQASTI IGNGDLLLQK PNRPQSSPED GQVATVSSSP ETKKDHPKTG 
AKTDCALHRI QNLAPSDEES SWTTLSQDSA SPSSPDETDI WSDHSFQTDP DLPPGWKRVS 
DIAGTYYWHI PTGTTQWERP VSIPADLQGS RKGSLSSVTP SPTPENEDLH AATVNPDPSL 
KEFEGATLRY ASLKLRNAPH PDDDDSCSIN SDPEAKCFAV RSLGWVEMAE EDLAPGKSSV 
AVNNCIRQLS YCKNDIRDTV GIWGEGKDMY LILENDMLSL VDPMDRSVLH SQPIVSIRVW 
GVGRDNGRDF AYVARDKDTR ILKCHVFRCD TPAKAIATSL HEICSKIMAE RKNAKALACS 
SLQERANVNL DVPLQVDFPT PKTELVQKFH VQYLGMLPVD KPVGMDILNS AIENLMTSSN 
KEDWLSVNMN VADATVTVIS EKNEEEVLVE CRVRFLSFMG VGKDVHTFAF IMDTGNQRFE 
CHVFWCEPNA GNVSEAVQAA CMLRYQKCLV ARPPSQKVRP PPPPADSVTR RVTTNVKRGV 
LSLIDTLKQK RPVTEMP

Genular Protein ID: 1554650348

Symbol: B4E2F2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4E2F2

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 2 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 758
  • Mass: 83345
  • Checksum: 1D006E02FE1B8E7D
  • Sequence:
    • MSEVLPADSG VDTLAVFMAS SGTTDVTNRN SPATPPNTLN LRSSHNELLN AEIKHTETKN 
STPPKCRKKY ALTNIQAAMG LSDPAAQPLL GNGSANIKLV KNGENQLRKA AEQGQQDPNK 
NLSPTAVINI TSEKLEGKEP HPQDSSSCEI LPSQPRRTKS FLNYYADLET SARELEQNQG 
NHHGTAEEKS QPVQGQASTI IGNGDLLLQK PNRPQSSPED GQVATVSSSP ETKKDHPKTG 
AKTDCALHRI QNLAPSDEES SWTTLSQDSA SPSSPDETDI WSDHSFQTDP DLPPGWKRVS 
DIAGTYYWHI PTGTTQWERP VSIPADLQGS RKGSLSSVTP SPTPENEKQP WSDFAVLNGG 
KINSDIWKDL HAATVNPDPS LKEFEGATLR YASLKLRNAP HPDDDDSCSI NSDPEAKCFA 
VRSLGWVEMA EEDLAPGKSS VAVNNCIRQL SYCKNDIRDT VGIWGEGKDM YLILENDMLS 
LVDPMDRSVL HSQPIVSIRV WGVGRDNGRD FAYVARDKDT RILKCHVFRC DTPAKAIATS 
LHEICSKIMA ERKNAKALAC SSLQERANVN LDVPLQVDFP TPKTELVQKF HVQYLGMLPV 
DKPVGMDILN SAIENLMTSS NKEDWLSVNM NVADATVTVI SEKNEKEVLV ECRVRFLSFM 
GVGKDVHTFA FIMDTGNQRF ECHVFWCEPN AGNVSEAVQA ACMLRYQKCL VARPPSQKVR 
PPPPPADSVT RRVTTNVKRG VLSLIDTLKQ KRPVTEMP

Genular Protein ID: 1103696923

Symbol: Q5I0G1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5I0G1

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 RefSeq 2 SMART 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 365
  • Mass: 40807
  • Checksum: 66E4F89A03CD60BB
  • Sequence:
    • LKLRNAPHPD DDDSCSINSD PEAKCFAVRS LGWVEMAEED LAPGKSSVAV NNCIRQLSYC 
KNDIRDTVGI WGEGKDMYLI LENDMLSLVD PMDRSVLHSQ PIVSIRVWGV GRDNGRDFAY 
VARDKDTRIL KCHVFRCDTP AKAIATSLHE ICSKIMAERK NAKALACSSL QERANVNLDV 
PLQVDFPTPK TELVQKFHVQ YLGMLPVDKP VGMDILNSAI ENLMTSSNKE DWLSVNMNVA 
DATVTVISEK NEEEVLVECR VRFLSFMGVG KDVHTFAFIM DTGNQRFECH VFWCEPNAGN 
VSEAVQAACM LRYQKCLVAR PPSQKVRPPP PPADSVTRRV TTNVKRGVLS LIDTLKQKRP 
VTEMP

Genular Protein ID: 3410679401

Symbol: B4DJ88_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DJ88

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 2 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 2 SAM 1 SMART 1 SUPFAM 2

Sequence Information:

  • Length: 471
  • Mass: 51366
  • Checksum: B628823EE1B1873C
  • Sequence:
    • MASSGTTDVT NRNSPATPPN TLNLRSSHNE LLNAEIKHTE TKNSTPPKCR KKYALTNIQA 
AMGLSDPAAQ PLLGNGSANI KLVKNGENQL RKAAEQGQQD PNKNLSPTAV INITSEKLEG 
KEPHPQDSSS CEILPSQPRR TKSFLNYYAD LETSARELEQ NRGNHHGTAE EKSQPVQGQA 
STIIGNGDLL LQKPNRPQSS PEDGQVATVS SSPETKKDHP KTGAKTDCAL HRIQNLAPSD 
EESSWTTLSQ DSASPSSPDE TDIWSDHSFQ TDPDLPPGWK RVSDIAGTYY WHIPTGTTQW 
ERPVSIPADL QGSRKGSLSS VTPSPTPENE DLHAATVNPD PSLKEFEGAT LRYASLKLRN 
APHPDDDDSC SINSDPEAKC FAVRSLGWVE MAEEDLAPGK SSVAVNNCIR QLSYCKNDIR 
DTVGIWGEGK DMYLILENDM LSLVDPMDRS VLHSQPIVSI RVWGVGRDNG R

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.