Details for: IFIT2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 87.1129
Cell Significance Index: -13.5500 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 52.7512
Cell Significance Index: -13.3800 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 30.3523
Cell Significance Index: -14.3300 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 27.9363
Cell Significance Index: -14.3700 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 11.1683
Cell Significance Index: -13.7700 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 4.4347
Cell Significance Index: -11.8800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 3.5428
Cell Significance Index: -13.9800 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 3.4707
Cell Significance Index: -10.6600 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.8834
Cell Significance Index: 27.9400 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 0.8532
Cell Significance Index: 12.9800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.7692
Cell Significance Index: 694.5000 - Cell Name: peg cell (CL4033014)
Fold Change: 0.7092
Cell Significance Index: 16.3900 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.6402
Cell Significance Index: 13.6400 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.6076
Cell Significance Index: 9.4000 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.5216
Cell Significance Index: 9.6400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.4803
Cell Significance Index: 52.2400 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.4521
Cell Significance Index: 73.5400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.4278
Cell Significance Index: 25.6800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.3502
Cell Significance Index: 22.5900 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.3247
Cell Significance Index: 41.6200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2726
Cell Significance Index: 18.8600 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.2430
Cell Significance Index: 4.3000 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 0.2231
Cell Significance Index: 1.3800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2110
Cell Significance Index: 40.1500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1622
Cell Significance Index: 16.0500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.1458
Cell Significance Index: 16.9900 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 0.1294
Cell Significance Index: 1.9500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1293
Cell Significance Index: 17.7500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0953
Cell Significance Index: 129.6000 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.0911
Cell Significance Index: 2.4800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.0856
Cell Significance Index: 4.0300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0473
Cell Significance Index: 9.4900 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.0470
Cell Significance Index: 1.2600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0435
Cell Significance Index: 66.8900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0432
Cell Significance Index: 1.9600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0399
Cell Significance Index: 14.3100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0351
Cell Significance Index: 1.0100 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0276
Cell Significance Index: 0.6900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0224
Cell Significance Index: 12.2600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0194
Cell Significance Index: 3.4900 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0170
Cell Significance Index: 31.3700 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 0.0107
Cell Significance Index: 0.5400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0101
Cell Significance Index: 2.0100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0057
Cell Significance Index: 2.5000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0015
Cell Significance Index: 2.9000 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: -0.0017
Cell Significance Index: -1.2100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0044
Cell Significance Index: -0.5500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0051
Cell Significance Index: -0.1800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0053
Cell Significance Index: -0.5400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0056
Cell Significance Index: -3.5700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0065
Cell Significance Index: -0.3400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0071
Cell Significance Index: -5.2100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0148
Cell Significance Index: -11.1800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0172
Cell Significance Index: -1.9700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0221
Cell Significance Index: -16.3400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0275
Cell Significance Index: -12.5000 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0289
Cell Significance Index: -16.2900 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0303
Cell Significance Index: -8.7200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0305
Cell Significance Index: -19.0600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0406
Cell Significance Index: -0.8800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0485
Cell Significance Index: -7.0500 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.0552
Cell Significance Index: -0.4500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0593
Cell Significance Index: -6.9900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0750
Cell Significance Index: -12.8200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0807
Cell Significance Index: -17.0000 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0826
Cell Significance Index: -3.3900 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0940
Cell Significance Index: -12.1500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1083
Cell Significance Index: -7.2800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1220
Cell Significance Index: -8.6300 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1251
Cell Significance Index: -13.0300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1354
Cell Significance Index: -6.3200 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1377
Cell Significance Index: -4.4100 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.1400
Cell Significance Index: -1.5900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1485
Cell Significance Index: -11.7600 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.1503
Cell Significance Index: -4.2000 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1592
Cell Significance Index: -12.2200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1627
Cell Significance Index: -9.9800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1689
Cell Significance Index: -12.5900 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1692
Cell Significance Index: -3.5100 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1867
Cell Significance Index: -4.8000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1891
Cell Significance Index: -11.6200 - Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: -0.1920
Cell Significance Index: -1.6500 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.2049
Cell Significance Index: -3.4300 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.2089
Cell Significance Index: -3.1300 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.2102
Cell Significance Index: -5.3700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.2122
Cell Significance Index: -11.1400 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.2268
Cell Significance Index: -6.5000 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.2349
Cell Significance Index: -13.1800 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.2452
Cell Significance Index: -6.5600 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.2459
Cell Significance Index: -15.5000 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.2719
Cell Significance Index: -4.6600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.2753
Cell Significance Index: -7.3500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.3028
Cell Significance Index: -13.4000 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.3123
Cell Significance Index: -6.6800 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.3283
Cell Significance Index: -11.5000 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.3559
Cell Significance Index: -2.1500 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.3578
Cell Significance Index: -13.5500 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.3734
Cell Significance Index: -13.7100 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.3830
Cell Significance Index: -12.5400 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.3896
Cell Significance Index: -5.5800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4174616661
Symbol: IFIT2_HUMAN
Name: Interferon-induced protein with tetratricopeptide repeats 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3466167
Title: Interferon-stimulated transcription: isolation of an inducible gene and identification of its regulatory region.
PubMed ID: 3466167
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 2454816
Title: Regulation of two interferon-inducible human genes by interferon, poly(rI).poly(rC) and viruses.
PubMed ID: 2454816
PubMed ID: 3360121
Title: The IFI-56K and IFI-54K interferon-inducible human genes belong to the same gene family.
PubMed ID: 3360121
PubMed ID: 16973618
Title: Distinct induction patterns and functions of two closely related interferon-inducible human genes, ISG54 and ISG56.
PubMed ID: 16973618
PubMed ID: 19416887
Title: ISG56 is a negative-feedback regulator of virus-triggered signaling and cellular antiviral response.
PubMed ID: 19416887
PubMed ID: 21190939
Title: The interferon stimulated gene 54 promotes apoptosis.
PubMed ID: 21190939
PubMed ID: 20950130
PubMed ID: 21642987
Title: IFIT1 is an antiviral protein that recognizes 5'-triphosphate RNA.
PubMed ID: 21642987
DOI: 10.1038/ni.2048
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 22825553
Title: Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms.
PubMed ID: 22825553
DOI: 10.1038/cr.2012.111
Sequence Information:
- Length: 472
- Mass: 54632
- Checksum: 3CF11319A5008FB9
- Sequence:
MSENNKNSLE SSLRQLKCHF TWNLMEGENS LDDFEDKVFY RTEFQNREFK ATMCNLLAYL KHLKGQNEAA LECLRKAEEL IQQEHADQAE IRSLVTWGNY AWVYYHMGRL SDVQIYVDKV KHVCEKFSSP YRIESPELDC EEGWTRLKCG GNQNERAKVC FEKALEKKPK NPEFTSGLAI ASYRLDNWPP SQNAIDPLRQ AIRLNPDNQY LKVLLALKLH KMREEGEEEG EGEKLVEEAL EKAPGVTDVL RSAAKFYRRK DEPDKAIELL KKALEYIPNN AYLHCQIGCC YRAKVFQVMN LRENGMYGKR KLLELIGHAV AHLKKADEAN DNLFRVCSIL ASLHALADQY EDAEYYFQKE FSKELTPVAK QLLHLRYGNF QLYQMKCEDK AIHHFIEGVK INQKSREKEK MKDKLQKIAK MRLSKNGADS EALHVLAFLQ ELNEKMQQAD EDSERGLESG SLIPSASSWN GE
Genular Protein ID: 110294346
Symbol: Q05DN2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 412
- Mass: 48070
- Checksum: 631B8287A772052F
- Sequence:
MSENNKNSLE SSLRQLKCHF TWNLMEGENS LDDFEDKVFY RTEFQNREFK ATMCNLLAYL KHLKGQNEAA LECLRKAEEL IQQEHADQAE IRSLVTWGNY AWVYYHMGRL SDVQIYVDKV KHVCEKFSSP YRIESPELDC EEGWTRLKCG GNQNERAKVC FEKALEKKPK NPEFTSGLAI ASYRLDNWPP SQNAIDPLRQ AIRLNPDNQY LKVLLALKLH KMREEGEEEG EGEKLVEEAL EKAPGVTDVL RSAAKFYRRK DEPDKAIELL KKALEYIPNN AYLHCQIGCC YRAKVFQVMN LRENGMYGKR KLLELIGHAV AHLKKADEAN DNLFRVCSIL ASLHALADQY EEAEYYFQKE FSKELTPVAK QLLHLRYGNF QLYQMKCEDK AIHHFIEGVK INQKKKKKKK KK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.