**Key characteristics:**
* IGLC4 is a member of the immunoglobulin lambda family of antibodies.
* It is expressed in various cell types, including precursor B cells, transitional stage B cells, IgG plasma cells, pro-B cells, B cells, plasma cells, pre-B-I cells, small pre-B-II cells, large pre-B-II cells, and memory B cells.
* It is a key regulator of B cell development and differentiation.
**Pathways and functions:**
* IGLC4 is involved in the regulation of B cell development. It is expressed in progenitor B cells and is required for the survival and differentiation of these cells into mature B cells.
* It also plays a role in the regulation of antibody production. IGLC4 is expressed in plasma cells, which are responsible for the production and secretion of antibodies. It is required for the assembly and secretion of antibodies by plasma cells.
* IGLC4 is also involved in the regulation of T cell responses. It is expressed in memory B cells, which are responsible for providing long-term immunity. IGLC4 on memory B cells is required for the generation of antibodies against specific antigens.
**Clinical significance:**
* Mutations in the IGLC4 gene have been linked to several human diseases, including autoimmune disorders and cancer.
* In autoimmune disorders, IGLC4 mutations can lead to the production of autoantibodies that target the body's own tissues.
* In cancer, IGLC4 mutations can lead to the activation of tumor cells and the development of cancer.
* IGLC4 is a promising target for the treatment of autoimmune disorders and cancer.
Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
