INHBA | ENSG00000122641 | NCBI 3624

Details for: INHBA

Gene ID: 3624

Symbol: INHBA

Ensembl ID: ENSG00000122641

Description: inhibin subunit beta A

Associated with

Antagonism of activin by follistatin
(R-HSA-2473224)
Glycoprotein hormones
(R-HSA-209822)
Metabolism of proteins
(R-HSA-392499)
Peptide hormone biosynthesis
(R-HSA-209952)
Peptide hormone metabolism
(R-HSA-2980736)
Signaling by activin
(R-HSA-1502540)
Signaling by bmp
(R-HSA-201451)
Signaling by tgfb family members
(R-HSA-9006936)
Signaling by tgfbr3
(R-HSA-9839373)
Signal transduction
(R-HSA-162582)
Tgfbr3 regulates activin signaling
(R-HSA-9839406)
Activin a complex
(GO:0043509)
Activin receptor signaling pathway
(GO:0032924)
Androgen metabolic process
(GO:0008209)
Androst-4-ene-3,17-dione biosynthetic process
(GO:1903449)
Autophagy
(GO:0006914)
Cardiac fibroblast cell development
(GO:0060936)
Cell-cell signaling
(GO:0007267)
Cell differentiation
(GO:0030154)
Cell surface receptor signaling pathway
(GO:0007166)
Cellular response to angiotensin
(GO:1904385)
Cellular response to cholesterol
(GO:0071397)
Cellular response to follicle-stimulating hormone stimulus
(GO:0071372)
Cellular response to hypoxia
(GO:0071456)
Cellular response to oxygen-glucose deprivation
(GO:0090650)
Cytokine-mediated signaling pathway
(GO:0019221)
Cytokine activity
(GO:0005125)
Defense response
(GO:0006952)
Endodermal cell differentiation
(GO:0035987)
Enzyme activator complex
(GO:0150005)
Erythrocyte differentiation
(GO:0030218)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Extrinsic apoptotic signaling pathway
(GO:0097191)
Eyelid development in camera-type eye
(GO:0061029)
Gabaergic neuron differentiation
(GO:0097154)
Growth factor activity
(GO:0008083)
Hair follicle development
(GO:0001942)
Hematopoietic progenitor cell differentiation
(GO:0002244)
Hemoglobin biosynthetic process
(GO:0042541)
Hormone activity
(GO:0005179)
Identical protein binding
(GO:0042802)
Inhibin a complex
(GO:0043512)
Male gonad development
(GO:0008584)
Mesodermal cell differentiation
(GO:0048333)
Negative regulation of b cell differentiation
(GO:0045578)
Negative regulation of cell growth
(GO:0030308)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of follicle-stimulating hormone secretion
(GO:0046882)
Negative regulation of g1/s transition of mitotic cell cycle
(GO:2000134)
Negative regulation of macrophage differentiation
(GO:0045650)
Negative regulation of phosphorylation
(GO:0042326)
Negative regulation of type ii interferon production
(GO:0032689)
Nervous system development
(GO:0007399)
Odontogenesis
(GO:0042476)
Ovarian follicle development
(GO:0001541)
Peptide hormone binding
(GO:0017046)
Perinuclear region of cytoplasm
(GO:0048471)
Positive regulation of collagen biosynthetic process
(GO:0032967)
Positive regulation of dna-templated transcription
(GO:0045893)
Positive regulation of erk1 and erk2 cascade
(GO:0070374)
Positive regulation of erythrocyte differentiation
(GO:0045648)
Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand
(GO:2001241)
Positive regulation of follicle-stimulating hormone secretion
(GO:0046881)
Positive regulation of gene expression
(GO:0010628)
Positive regulation of ovulation
(GO:0060279)
Positive regulation of protein metabolic process
(GO:0051247)
Positive regulation of smad protein signal transduction
(GO:0060391)
Positive regulation of transcription by rna polymerase ii
(GO:0045944)
Positive regulation of transcription by rna polymerase iii
(GO:0045945)
Progesterone secretion
(GO:0042701)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Regulation of follicle-stimulating hormone secretion
(GO:0046880)
Regulation of transcription by rna polymerase ii
(GO:0006357)
Response to aldosterone
(GO:1904044)
Response to wounding
(GO:0009611)
Roof of mouth development
(GO:0060021)
Sertoli cell differentiation
(GO:0060008)
Smad protein signal transduction
(GO:0060395)
Striatal medium spiny neuron differentiation
(GO:0021773)
Testosterone biosynthetic process
(GO:0061370)
Transcription by rna polymerase ii
(GO:0006366)
Type ii activin receptor binding
(GO:0070699)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 68.8368
Cell Significance Index: -17.4600
Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 4.4095
Cell Significance Index: -17.4000
Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 2.0357
Cell Significance Index: 42.6100
Cell Name: monocyte-derived dendritic cell (CL0011031)
Fold Change: 1.6554
Cell Significance Index: 28.4400
Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 1.3560
Cell Significance Index: 43.4300
Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.9297
Cell Significance Index: 26.6500
Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 0.8841
Cell Significance Index: 5.9900
Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.7517
Cell Significance Index: 11.6300
Cell Name: chondroblast (CL0000058)
Fold Change: 0.6508
Cell Significance Index: 3.8200
Cell Name: endocardial cell (CL0002350)
Fold Change: 0.4522
Cell Significance Index: 2.6700
Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: 0.3299
Cell Significance Index: 37.6600
Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: 0.3165
Cell Significance Index: 2.7200
Cell Name: perivascular cell (CL4033054)
Fold Change: 0.2707
Cell Significance Index: 1.2500
Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.2528
Cell Significance Index: 466.2800
Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.2459
Cell Significance Index: 378.5100
Cell Name: odontoblast (CL0000060)
Fold Change: 0.1453
Cell Significance Index: 18.6300
Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1315
Cell Significance Index: 25.0300
Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.1062
Cell Significance Index: 4.9500
Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.1034
Cell Significance Index: 65.6400
Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0998
Cell Significance Index: 9.8800
Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 0.0810
Cell Significance Index: 4.0900
Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.0803
Cell Significance Index: 4.8200
Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0702
Cell Significance Index: 14.0700
Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.0465
Cell Significance Index: 3.1300
Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.0301
Cell Significance Index: 1.3300
Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0098
Cell Significance Index: 6.7700
Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0027
Cell Significance Index: 0.0500
Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0003
Cell Significance Index: 0.5500
Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0000
Cell Significance Index: 0.0000
Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0010
Cell Significance Index: -0.7700
Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0011
Cell Significance Index: -0.4700
Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0052
Cell Significance Index: -3.2200
Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0056
Cell Significance Index: -3.1800
Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0057
Cell Significance Index: -7.7400
Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0130
Cell Significance Index: -5.8900
Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.0133
Cell Significance Index: -1.4500
Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0193
Cell Significance Index: -6.9400
Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0216
Cell Significance Index: -15.8200
Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0216
Cell Significance Index: -16.3400
Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0227
Cell Significance Index: -12.3900
Cell Name: lactocyte (CL0002325)
Fold Change: -0.0250
Cell Significance Index: -3.2300
Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0264
Cell Significance Index: -3.8400
Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0302
Cell Significance Index: -6.3600
Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0313
Cell Significance Index: -5.3400
Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0340
Cell Significance Index: -0.9800
Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0412
Cell Significance Index: -5.6600
Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0417
Cell Significance Index: -1.5800
Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0457
Cell Significance Index: -13.1600
Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0493
Cell Significance Index: -9.7800
Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0517
Cell Significance Index: -2.4300
Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0648
Cell Significance Index: -11.6800
Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.0675
Cell Significance Index: -10.9900
Cell Name: granulosa cell (CL0000501)
Fold Change: -0.0856
Cell Significance Index: -2.2500
Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0892
Cell Significance Index: -1.8500
Cell Name: trophoblast giant cell (CL0002488)
Fold Change: -0.0958
Cell Significance Index: -0.6900
Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.1013
Cell Significance Index: -12.4500
Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.1029
Cell Significance Index: -4.2200
Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.1141
Cell Significance Index: -5.1700
Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1215
Cell Significance Index: -12.4100
Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.1228
Cell Significance Index: -1.8500
Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.1251
Cell Significance Index: -2.7100
Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1260
Cell Significance Index: -14.6800
Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.1292
Cell Significance Index: -8.9400
Cell Name: alveolar macrophage (CL0000583)
Fold Change: -0.1351
Cell Significance Index: -1.1900
Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1415
Cell Significance Index: -16.2100
Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.1464
Cell Significance Index: -3.6600
Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1479
Cell Significance Index: -10.4600
Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1508
Cell Significance Index: -11.5700
Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1523
Cell Significance Index: -17.9600
Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1645
Cell Significance Index: -17.1300
Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.1900
Cell Significance Index: -5.3100
Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2009
Cell Significance Index: -15.9100
Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.2062
Cell Significance Index: -5.3000
Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2243
Cell Significance Index: -16.7200
Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.2680
Cell Significance Index: -17.2900
Cell Name: extravillous trophoblast (CL0008036)
Fold Change: -0.2816
Cell Significance Index: -1.7500
Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.2861
Cell Significance Index: -12.4400
Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.2880
Cell Significance Index: -10.1200
Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.2924
Cell Significance Index: -17.9800
Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.3210
Cell Significance Index: -4.6100
Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.3403
Cell Significance Index: -2.7800
Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.3518
Cell Significance Index: -19.7400
Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.3558
Cell Significance Index: -18.6800
Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3618
Cell Significance Index: -22.8000
Cell Name: fibroblast of breast (CL4006000)
Fold Change: -0.3689
Cell Significance Index: -2.3200
Cell Name: melanocyte of skin (CL1000458)
Fold Change: -0.3717
Cell Significance Index: -5.2100
Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.3825
Cell Significance Index: -19.8700
Cell Name: cytotoxic T cell (CL0000910)
Fold Change: -0.3938
Cell Significance Index: -5.7400
Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.4146
Cell Significance Index: -8.8300
Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.4291
Cell Significance Index: -14.9100
Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.4481
Cell Significance Index: -16.4500
Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.4594
Cell Significance Index: -13.1100
Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.4669
Cell Significance Index: -7.8700
Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.4848
Cell Significance Index: -14.2800
Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.4875
Cell Significance Index: -13.2700
Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.4996
Cell Significance Index: -15.8000
Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: -0.5033
Cell Significance Index: -4.7800
Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.5190
Cell Significance Index: -18.1800
Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.5210
Cell Significance Index: -9.6300
Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.5316
Cell Significance Index: -8.7600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

**Key Characteristics** 1. **Structure**: The INHBA gene consists of 11 exons and encodes for the beta A subunit of inhibin, which is a 32-kDa protein. 2. **Expression**: The INHBA gene is highly expressed in various tissues, including the endocardium, bronchus fibroblasts, lens epithelial cells, and intestinal crypt stem cells. 3. **Function**: The beta A subunit of inhibin plays a crucial role in regulating reproductive physiology, bone metabolism, and cellular differentiation. 4. **Regulation**: The INHBA gene is regulated by various transcription factors, including Smad proteins, which are involved in the signaling pathways of activin and TGF-beta. 5. **Disease association**: Dysregulation of the INHBA gene has been implicated in several diseases, including cancer, cardiovascular disorders, and reproductive disorders. **Pathways and Functions** 1. **Activin signaling pathway**: The INHBA gene is involved in the activin signaling pathway, which regulates various cellular processes, including cell growth, differentiation, and apoptosis. 2. **TGF-beta signaling pathway**: The INHBA gene is also involved in the TGF-beta signaling pathway, which regulates cellular processes, including cell growth, differentiation, and apoptosis. 3. **Smad protein signal transduction**: The INHBA gene encodes for the beta A subunit of inhibin, which interacts with Smad proteins to regulate the signaling pathways of activin and TGF-beta. 4. **Cellular differentiation**: The INHBA gene plays a crucial role in regulating cellular differentiation, including the differentiation of endocardial cells, lens epithelial cells, and intestinal crypt stem cells. 5. **Reproductive physiology**: The INHBA gene is involved in regulating reproductive physiology, including the regulation of follicle-stimulating hormone secretion and ovulation. **Clinical Significance** 1. **Cancer**: Dysregulation of the INHBA gene has been implicated in several types of cancer, including ovarian, breast, and prostate cancer. 2. **Cardiovascular disorders**: The INHBA gene is involved in regulating cardiovascular physiology, and dysregulation of the INHBA gene has been implicated in cardiovascular disorders, including atherosclerosis and heart failure. 3. **Reproductive disorders**: The INHBA gene plays a crucial role in regulating reproductive physiology, and dysregulation of the INHBA gene has been implicated in reproductive disorders, including infertility and polycystic ovary syndrome. 4. **Bone metabolism**: The INHBA gene is involved in regulating bone metabolism, and dysregulation of the INHBA gene has been implicated in bone disorders, including osteoporosis and bone cancer. In conclusion, the INHBA gene plays a crucial role in regulating various biological processes, including reproductive physiology, bone metabolism, and cellular differentiation. Dysregulation of the INHBA gene has been implicated in several diseases, including cancer, cardiovascular disorders, and reproductive disorders. Further research is needed to fully understand the mechanisms of INHBA gene regulation and its clinical significance.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

Inhibin beta A chain

Genular Protein ID: 1440607932

Symbol: INHBA_HUMAN

Name: Inhibin beta A chain

UniProtKB Accession Codes:

P08476 Q14599

Database IDs:

Citations:

PubMed ID: 3754442

Title: Structure of two human ovarian inhibins.

PubMed ID: 3754442

DOI: 10.1016/0006-291x(86)91021-1

PubMed ID: 3267209

Title: Erythroid differentiation factor is encoded by the same mRNA as that of the inhibin beta A chain.

PubMed ID: 3267209

DOI: 10.1073/pnas.85.8.2434

PubMed ID: 1777673

Title: Structure and sequence analysis of the human activin beta A subunit gene.

PubMed ID: 1777673

DOI: 10.3109/10425179109039678

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3758355

Title: Human inhibin genes. Genomic characterisation and sequencing.

PubMed ID: 3758355

DOI: 10.1016/0014-5793(86)81006-7

PubMed ID: 12697670

Title: Differential binding and neutralization of activins A and B by follistatin and follistatin like-3 (FSTL-3/FSRP/FLRG).

PubMed ID: 12697670

DOI: 10.1210/en.2002-0203

PubMed ID: 12660162

Title: Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions.

PubMed ID: 12660162

DOI: 10.1093/emboj/cdg156

PubMed ID: 18768470

Title: The structure of FSTL3.activin A complex. Differential binding of N-terminal domains influences follistatin-type antagonist specificity.

PubMed ID: 18768470

DOI: 10.1074/jbc.m801266200

PubMed ID: 24302632

Title: Germline mutations of inhibins in early-onset ovarian epithelial tumors.

PubMed ID: 24302632

DOI: 10.1002/humu.22489

Sequence Information:

Length: 426
Mass: 47442
Checksum: 201CDEDF99CB6919
Sequence:

MPLLWLRGFL LASCWIIVRS SPTPGSEGHS AAPDCPSCAL AALPKDVPNS QPEMVEAVKK 
HILNMLHLKK RPDVTQPVPK AALLNAIRKL HVGKVGENGY VEIEDDIGRR AEMNELMEQT 
SEIITFAESG TARKTLHFEI SKEGSDLSVV ERAEVWLFLK VPKANRTRTK VTIRLFQQQK 
HPQGSLDTGE EAEEVGLKGE RSELLLSEKV VDARKSTWHV FPVSSSIQRL LDQGKSSLDV 
RIACEQCQES GASLVLLGKK KKKEEEGEGK KKGGGEGGAG ADEEKEQSHR PFLMLQARQS 
EDHPHRRRRR GLECDGKVNI CCKKQFFVSF KDIGWNDWII APSGYHANYC EGECPSHIAG 
TSGSSLSFHS TVINHYRMRG HSPFANLKSC CVPTKLRPMS MLYYDDGQNI IKKDIQNMIV 
EECGCS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: INHBA

Associated with

Cells (max top 100)

Other Information

Structure of two human ovarian inhibins. PubMed ID: 3754442

Erythroid differentiation factor is encoded by the same mRNA as that of the inhibin beta A chain. PubMed ID: 3267209

Structure and sequence analysis of the human activin beta A subunit gene. PubMed ID: 1777673

The DNA sequence of human chromosome 7. PubMed ID: 12853948

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Human inhibin genes. Genomic characterisation and sequencing. PubMed ID: 3758355

Differential binding and neutralization of activins A and B by follistatin and follistatin like-3 (FSTL-3/FSRP/FLRG). PubMed ID: 12697670

Structures of an ActRIIB:activin A complex reveal a novel binding mode for TGF-beta ligand:receptor interactions. PubMed ID: 12660162

The structure of FSTL3.activin A complex. Differential binding of N-terminal domains influences follistatin-type antagonist specificity. PubMed ID: 18768470

Germline mutations of inhibins in early-onset ovarian epithelial tumors. PubMed ID: 24302632