Details for: INPP5B

Gene ID: 3633

Symbol: INPP5B

Ensembl ID: ENSG00000204084

Description: inositol polyphosphate-5-phosphatase B

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 147.8027
    Cell Significance Index: -22.9900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 91.9795
    Cell Significance Index: -23.3300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 49.9930
    Cell Significance Index: -20.3100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 21.4194
    Cell Significance Index: -20.4500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 19.9439
    Cell Significance Index: -24.5900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 8.4621
    Cell Significance Index: -18.5200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 8.4514
    Cell Significance Index: -22.6400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.3177
    Cell Significance Index: -24.9300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.7507
    Cell Significance Index: 333.1700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.7188
    Cell Significance Index: 344.7900
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 1.1618
    Cell Significance Index: 11.7200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.1399
    Cell Significance Index: 408.8500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.0803
    Cell Significance Index: 106.8700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.0425
    Cell Significance Index: 80.0000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.8505
    Cell Significance Index: 22.7900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.7415
    Cell Significance Index: 512.8300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.6548
    Cell Significance Index: 12.7800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.6306
    Cell Significance Index: 16.2100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5993
    Cell Significance Index: 97.4700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5597
    Cell Significance Index: 111.0700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4737
    Cell Significance Index: 51.5300
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.4535
    Cell Significance Index: 5.6300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.4304
    Cell Significance Index: 10.7600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2870
    Cell Significance Index: 13.0100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2698
    Cell Significance Index: 31.8200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2603
    Cell Significance Index: 7.5000
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.2263
    Cell Significance Index: 3.2500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.2077
    Cell Significance Index: 391.1200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1703
    Cell Significance Index: 10.2300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.1682
    Cell Significance Index: 10.3400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1529
    Cell Significance Index: 2.6200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1496
    Cell Significance Index: 67.9000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1378
    Cell Significance Index: 24.8400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.1318
    Cell Significance Index: 8.8600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1081
    Cell Significance Index: 3.8000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0706
    Cell Significance Index: 1.5300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0652
    Cell Significance Index: 100.3700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0649
    Cell Significance Index: 119.7700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0627
    Cell Significance Index: 39.7900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0581
    Cell Significance Index: 4.0200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0541
    Cell Significance Index: 7.4300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0439
    Cell Significance Index: 59.6900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0435
    Cell Significance Index: 2.7400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0305
    Cell Significance Index: 1.7100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0256
    Cell Significance Index: 1.6500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0250
    Cell Significance Index: 3.0800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0175
    Cell Significance Index: 9.5700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0111
    Cell Significance Index: 4.9200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.0098
    Cell Significance Index: 0.2800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0218
    Cell Significance Index: -2.2700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0241
    Cell Significance Index: -3.5100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0243
    Cell Significance Index: -17.8400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0265
    Cell Significance Index: -20.0500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0266
    Cell Significance Index: -19.7200
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.0344
    Cell Significance Index: -0.5000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0381
    Cell Significance Index: -21.5000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0435
    Cell Significance Index: -27.1800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0639
    Cell Significance Index: -10.9200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0697
    Cell Significance Index: -1.8600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0725
    Cell Significance Index: -20.8500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0792
    Cell Significance Index: -1.9000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0812
    Cell Significance Index: -10.4100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.0967
    Cell Significance Index: -2.0700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1015
    Cell Significance Index: -11.8300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1083
    Cell Significance Index: -11.0600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1158
    Cell Significance Index: -3.7100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1208
    Cell Significance Index: -5.6300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1215
    Cell Significance Index: -2.6600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1237
    Cell Significance Index: -26.0500
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1306
    Cell Significance Index: -2.2000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1422
    Cell Significance Index: -16.3000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1456
    Cell Significance Index: -3.0900
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.1524
    Cell Significance Index: -1.9000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1617
    Cell Significance Index: -20.8900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2154
    Cell Significance Index: -6.0200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.2206
    Cell Significance Index: -3.0100
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.2227
    Cell Significance Index: -3.6700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2261
    Cell Significance Index: -11.7500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2321
    Cell Significance Index: -12.0900
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2411
    Cell Significance Index: -3.5600
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.2471
    Cell Significance Index: -2.1000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2477
    Cell Significance Index: -5.2800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2627
    Cell Significance Index: -19.5800
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.2694
    Cell Significance Index: -3.4000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2739
    Cell Significance Index: -13.8400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2770
    Cell Significance Index: -13.0200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2812
    Cell Significance Index: -22.2700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2821
    Cell Significance Index: -19.9500
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.2823
    Cell Significance Index: -6.1000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3037
    Cell Significance Index: -6.3000
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.3154
    Cell Significance Index: -4.6600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3156
    Cell Significance Index: -13.9600
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.3271
    Cell Significance Index: -7.9800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3312
    Cell Significance Index: -17.3900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3331
    Cell Significance Index: -10.6100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.3757
    Cell Significance Index: -5.3800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3830
    Cell Significance Index: -23.4800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3896
    Cell Significance Index: -12.7600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3924
    Cell Significance Index: -14.8600
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.4020
    Cell Significance Index: -8.0700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** INPP5B is a type II inositol 1,4,5-trisphosphate 5-phosphatase, which specifically hydrolyzes the inositol phosphate molecules ip3 and ip4. This enzyme is crucial for regulating the activity of protein kinases and phosphatases, which are essential for various cellular signaling pathways. INPP5B has been shown to interact with multiple proteins, including kinases, phosphatases, and adaptors, to modulate its activity and specificity. The enzyme has also been implicated in the regulation of cell growth, differentiation, and survival. **Pathways and Functions:** INPP5B is involved in various cellular signaling pathways, including: 1. **Inositol phosphate metabolism:** INPP5B plays a crucial role in the breakdown of inositol phosphates, which are essential messengers in cellular communication. 2. **Signal transduction:** INPP5B modulates the activity of protein kinases and phosphatases, which are essential for various cellular signaling pathways. 3. **Metabolism:** INPP5B is involved in the regulation of glucose and lipid metabolism, and has been implicated in the development of metabolic disorders. 4. **Neurological disorders:** INPP5B has been implicated in the pathogenesis of various neurological disorders, including Alzheimer's disease, Parkinson's disease, and schizophrenia. 5. **Cancer:** INPP5B has been shown to be overexpressed in several types of cancer, including breast, lung, and colon cancer. **Clinical Significance:** Dysregulation of INPP5B has been implicated in several diseases, including: 1. **Neurological disorders:** INPP5B has been implicated in the pathogenesis of Alzheimer's disease, Parkinson's disease, and schizophrenia. 2. **Cancer:** INPP5B has been shown to be overexpressed in several types of cancer, including breast, lung, and colon cancer. 3. **Metabolic disorders:** INPP5B has been implicated in the development of metabolic disorders, including type 2 diabetes and obesity. 4. **Neuropsychiatric disorders:** INPP5B has been implicated in the pathogenesis of neuropsychiatric disorders, including anxiety and depression. In conclusion, INPP5B is a crucial enzyme involved in various cellular signaling pathways, and its dysregulation has been implicated in several diseases. Further research is needed to fully understand the role of INPP5B in human disease and to develop therapeutic strategies to target this enzyme. **Potential therapeutic applications:** 1. **Treatment of neurological disorders:** INPP5B inhibitors or activators could be used to treat Alzheimer's disease, Parkinson's disease, and schizophrenia. 2. **Cancer therapy:** INPP5B inhibitors or activators could be used to treat cancer by modulating the activity of protein kinases and phosphatases. 3. **Metabolic disorder treatment:** INPP5B inhibitors or activators could be used to treat metabolic disorders, such as type 2 diabetes and obesity. 4. **Neuropsychiatric disorder treatment:** INPP5B inhibitors or activators could be used to treat neuropsychiatric disorders, such as anxiety and depression. Overall, INPP5B is a promising target for therapeutic intervention in various diseases, and further research is needed to fully understand its role in human disease.

Genular Protein ID: 1950503692

Symbol: I5P2_HUMAN

Name: Type II inositol 1,4,5-trisphosphate 5-phosphatase

UniProtKB Accession Codes:

P32019 C9J6U5 Q5VSG9 Q5VSH0 Q5VSH1 Q658Q5 Q6P6D4 Q6PD53 Q86YE1

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 3 CTD 1 ChEBI 6 ChEMBL 1 ChiTaRS 1 DEPOD 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EC 2 EMBL 7 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 18 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 10 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 5 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 2 RefSeq 2 Rhea 1 SABIO-RK 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 2 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7721860

Title: Properties of type II inositol polyphosphate 5-phosphatase.

PubMed ID: 7721860

DOI: 10.1074/jbc.270.16.9370

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 1718960

Title: Cloning and expression of human 75-kDa inositol polyphosphate-5-phosphatase.

PubMed ID: 1718960

DOI: 10.1016/s0021-9258(18)54920-6

PubMed ID: 17956944

Title: Targeting of the type II inositol polyphosphate 5-phosphatase INPP5B to the early secretory pathway.

PubMed ID: 17956944

DOI: 10.1242/jcs.014423

PubMed ID: 20133602

Title: Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1.

PubMed ID: 20133602

DOI: 10.1073/pnas.0914658107

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21233288

Title: The PH domain proteins IPIP27A and B link OCRL1 to receptor recycling in the endocytic pathway.

PubMed ID: 21233288

DOI: 10.1091/mbc.e10-08-0730

PubMed ID: 25869668

Title: Sac2/INPP5F is an inositol 4-phosphatase that functions in the endocytic pathway.

PubMed ID: 25869668

DOI: 10.1083/jcb.201409064

PubMed ID: 26824392

Title: Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.

PubMed ID: 26824392

DOI: 10.7554/elife.12813

Sequence Information:

  • Length: 993
  • Mass: 112852
  • Checksum: ABD3581CC6CD29D6
  • Sequence:
    • MDQSVAIQET LAEGEYCVIA VQGVLCEGDS RQSRLLGLVR YRLEHGGQEH ALFLYTHRRM 
AITGDDVSLD QIVPVSRDFT LEEVSPDGEL YILGSDVTVQ LDTAELSLVF QLPFGSQTRM 
FLHEVARACP GFDSATRDPE FLWLSRYRCA ELELEMPTPR GCNSALVTWP GYATIGGGRY 
PSRKKRWGLE EARPQGAGSV LFWGGAMEKT GFRLMERAHG GGFVWGRSAR DGRRDEELEE 
AGREMSAAAG SRERNTAGGS NFDGLRPNGK GVPMDQSSRG QDKPESLQPR QNKSKSEITD 
MVRSSTITVS DKAHILSMQK FGLRDTIVKS HLLQKEEDYT YIQNFRFFAG TYNVNGQSPK 
ECLRLWLSNG IQAPDVYCVG FQELDLSKEA FFFHDTPKEE EWFKAVSEGL HPDAKYAKVK 
LIRLVGIMLL LYVKQEHAAY ISEVEAETVG TGIMGRMGNK GGVAIRFQFH NTSICVVNSH 
LAAHIEEYER RNQDYKDICS RMQFCQPDPS LPPLTISNHD VILWLGDLNY RIEELDVEKV 
KKLIEEKDFQ MLYAYDQLKI QVAAKTVFEG FTEGELTFQP TYKYDTGSDD WDTSEKCRAP 
AWCDRILWKG KNITQLSYQS HMALKTSDHK PVSSVFDIGV RVVNDELYRK TLEEIVRSLD 
KMENANIPSV SLSKREFCFQ NVKYMQLKVE SFTIHNGQVP CHFEFINKPD EESYCKQWLN 
ANPSRGFLLP DSDVEIDLEL FVNKMTATKL NSGEDKIEDI LVLHLDRGKD YFLSVSGNYL 
PSCFGSPIHT LCYMREPILD LPLETISELT LMPVWTGDDG SQLDSPMEIP KELWMMVDYL 
YRNAVQQEDL FQQPGLRSEF EHIRDCLDTG MIDNLSASNH SVAEALLLFL ESLPEPVICY 
STYHNCLECS GNYTASKQVI STLPIFHKNV FHYLMAFLRE LLKNSAKNHL DENILASIFG 
SLLLRNPAGH QKLDMTEKKK AQEFIHQFLC NPL

Genular Protein ID: 667642376

Symbol: B3KMW4_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KMW4

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 3 InterPro 9 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 3 RefSeq 1 SAM 1 SMART 2 SUPFAM 2

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 749
  • Mass: 85642
  • Checksum: 083F0027A2664F7D
  • Sequence:
    • MSAAASSRER NTAGGSNFDG LRPNGKGVPM DQSSRGQDKP ESLQPRQNKS KSEITDMVRS 
STITVSDKAH ILSMQKFGLR DTIVKSHLLQ KEEDYTYIQN FRFFAGTYNV NGQSPKECLR 
LWLSNGIQAP DVYCVGFQEL DLSKEAFFFH DTPKEEEWFK AVSEGLHPDA KYAKVKLIRL 
VGIMLLLYVK QEHAAYISEV EAETVGTGIM GRMGNKGGVA IRFQFHNTSI CVVNSHLAAH 
IEEYERRNQD YKDICSRMQF CQPDPSLPPL TISNHDVILW LGDLNYRIEE LDVEKVKKLI 
EEKDFQMLYA YDQLKIQVAA KTVFEGFTEG ELTFQPTYKY DTGSDDWDTS EKCRAPAWCD 
RILWKGKNIT QLSYQSHMAL KTSDHKPVSS VFDIGVRVVN DELYRKTLEE IVRSLDKMEN 
ANIPSVSLSK REFCFQNVKY MQLKVESFTI HNGQVPCHFE FINKPDEESY CKQWLNANPS 
RGFLLPDSDV EIDLELFVNK TTATKLNSGE DKIEDILVLH LDRGKDYFLS VSGNYLPSCF 
GSPIHTLCYM REPILDLPLE TISELTLMPV WTGDDGSQLD SPMEIPKELW MMVDYLYRNA 
VQQEDLFQQP GLRSEFEHIR DCLDTGMIDN LSASNHSVAE ALLLFLESLP EPVICYSTYH 
NCLECSGNYT ASKQVISTLP IFHKNVFHYL MAFLRELLKN SAKNHLHENI LASIFGSLLL 
RNPAGHQKLD MTEKKKAQEF IHQFLCNPL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.