Details for: ITIH1

Gene ID: 3697

Symbol: ITIH1

Ensembl ID: ENSG00000055957

Description: inter-alpha-trypsin inhibitor heavy chain 1

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 6.93
    Marker Score: 22,703
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 2.28
    Marker Score: 12,275
  • Cell Name: plasma cell (CL0000786)
    Fold Change: 1.83
    Marker Score: 2,044
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.82
    Marker Score: 7,870
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.69
    Marker Score: 10,881
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.38
    Marker Score: 876
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.16
    Marker Score: 1,247
  • Cell Name: goblet cell (CL0000160)
    Fold Change: 1.16
    Marker Score: 7,692
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.08
    Marker Score: 406
  • Cell Name: inflammatory macrophage (CL0000863)
    Fold Change: 1.04
    Marker Score: 324
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.02
    Marker Score: 2,588
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: 0.99
    Marker Score: 548
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,409
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.94
    Marker Score: 5,357
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.92
    Marker Score: 2,741
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 0.88
    Marker Score: 552
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,296
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.87
    Marker Score: 663
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.81
    Marker Score: 553
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1,265
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.78
    Marker Score: 711
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 0.73
    Marker Score: 726
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.7
    Marker Score: 180
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.61
    Marker Score: 483
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 0.52
    Marker Score: 142
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: 0.5
    Marker Score: 479
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.47
    Marker Score: 125
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.4
    Marker Score: 808
  • Cell Name: mast cell (CL0000097)
    Fold Change: 0.37
    Marker Score: 216
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.37
    Marker Score: 375
  • Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
    Fold Change: 0.33
    Marker Score: 684
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 0.32
    Marker Score: 169
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.31
    Marker Score: 578
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: 0.3
    Marker Score: 306
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 0.3
    Marker Score: 314
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.29
    Marker Score: 4,544
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 0.23
    Marker Score: 172
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 0.2
    Marker Score: 63
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.18
    Marker Score: 40
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.17
    Marker Score: 56
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.17
    Marker Score: 69
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 0.15
    Marker Score: 55
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.15
    Marker Score: 70
  • Cell Name: muscle cell (CL0000187)
    Fold Change: 0.14
    Marker Score: 41
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.13
    Marker Score: 80
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.12
    Marker Score: 66
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: 0.11
    Marker Score: 91
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.1
    Marker Score: 65
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.08
    Marker Score: 193
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 0.08
    Marker Score: 188
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 0.07
    Marker Score: 51
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.07
    Marker Score: 19
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 0.06
    Marker Score: 23
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.06
    Marker Score: 79
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: 0.06
    Marker Score: 41
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.06
    Marker Score: 69
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.06
    Marker Score: 26
  • Cell Name: gamma-delta T cell (CL0000798)
    Fold Change: 0.06
    Marker Score: 39
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.06
    Marker Score: 48
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 0.06
    Marker Score: 88
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: 0.05
    Marker Score: 29
  • Cell Name: blood vessel smooth muscle cell (CL0019018)
    Fold Change: 0.05
    Marker Score: 14
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: 0.05
    Marker Score: 19
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: 0.05
    Marker Score: 24
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.05
    Marker Score: 23
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 0.05
    Marker Score: 51
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.05
    Marker Score: 45
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 0.05
    Marker Score: 13
  • Cell Name: pericyte (CL0000669)
    Fold Change: 0.05
    Marker Score: 28
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 0.05
    Marker Score: 13
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: 0.05
    Marker Score: 21
  • Cell Name: vascular associated smooth muscle cell (CL0000359)
    Fold Change: 0.05
    Marker Score: 21
  • Cell Name: type D enteroendocrine cell (CL0000502)
    Fold Change: 0.05
    Marker Score: 14
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.04
    Marker Score: 14
  • Cell Name: neutrophil (CL0000775)
    Fold Change: 0.04
    Marker Score: 27
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 0.04
    Marker Score: 33
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.04
    Marker Score: 22
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 0.04
    Marker Score: 40
  • Cell Name: neuroendocrine cell (CL0000165)
    Fold Change: 0.04
    Marker Score: 16
  • Cell Name: tracheobronchial smooth muscle cell (CL0019019)
    Fold Change: 0.04
    Marker Score: 12
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 0.04
    Marker Score: 10
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.04
    Marker Score: 27
  • Cell Name: transitional stage B cell (CL0000818)
    Fold Change: 0.04
    Marker Score: 14
  • Cell Name: sympathetic neuron (CL0011103)
    Fold Change: 0.04
    Marker Score: 13
  • Cell Name: enterocyte of colon (CL1000347)
    Fold Change: 0.04
    Marker Score: 59
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.04
    Marker Score: 679
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: 0.04
    Marker Score: 61
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.04
    Marker Score: 14
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.04
    Marker Score: 11
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: 0.04
    Marker Score: 36
  • Cell Name: B cell (CL0000236)
    Fold Change: 0.04
    Marker Score: 35
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.04
    Marker Score: 9
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 0.03
    Marker Score: 21
  • Cell Name: group 3 innate lymphoid cell (CL0001071)
    Fold Change: 0.03
    Marker Score: 14
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: 0.03
    Marker Score: 42
  • Cell Name: type I enteroendocrine cell (CL0002277)
    Fold Change: 0.03
    Marker Score: 8
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.03
    Marker Score: 10
  • Cell Name: type G enteroendocrine cell (CL0000508)
    Fold Change: 0.03
    Marker Score: 11
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 0.03
    Marker Score: 13
  • Cell Name: conventional dendritic cell (CL0000990)
    Fold Change: 0.03
    Marker Score: 21

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Structure:** ITIH1 consists of two heavy chains and one light chain, which are linked together by disulfide bonds. The heavy chains possess a unique structure that allows them to bind to multiple ligands. 2. **Expression:** ITIH1 is expressed in various cell types, including hepatocytes, plasma cells, granulocytes, and endothelial cells, suggesting its involvement in multiple cellular processes. 3. **Ligand binding:** ITIH1 binds to hyaluronic acid, collagen, and calcium ions, which are essential for its function and regulation. 4. **Serine-type endopeptidase inhibitor activity:** ITIH1 possesses serine-type endopeptidase inhibitor activity, which is crucial for regulating proteolytic processes. **Pathways and Functions:** 1. **Hyaluronic acid binding:** ITIH1 binds to hyaluronic acid, which is involved in cell migration, wound healing, and cancer metastasis. 2. **Collagen binding:** ITIH1 binds to collagen, which is essential for maintaining the structure and integrity of the extracellular matrix. 3. **Calcium ion binding:** ITIH1 binds to calcium ions, which play a crucial role in various cellular processes, including cell signaling and protein folding. 4. **Blood microparticle formation:** ITIH1 is involved in the formation of blood microparticles, which are small vesicles released from cells that play a role in intercellular communication. 5. **Extracellular exosome formation:** ITIH1 is also involved in the formation of extracellular exosomes, which are small vesicles released by cells that play a role in intercellular communication. **Clinical Significance:** 1. **Liver disease:** ITIH1 is significantly expressed in liver cells, suggesting its involvement in liver disease, including hepatitis and cirrhosis. 2. **Cancer:** ITIH1 has been implicated in cancer progression, including metastasis and angiogenesis. 3. **Inflammatory diseases:** ITIH1 has been shown to play a role in inflammatory diseases, including rheumatoid arthritis and atherosclerosis. 4. **Wound healing:** ITIH1 is involved in wound healing, including cell migration and tissue repair. In conclusion, ITIH1 is a multifunctional protein that plays a crucial role in various physiological and pathological processes. Its involvement in liver disease, cancer, inflammatory diseases, and wound healing highlights its significance in human health and disease. Further research is necessary to fully elucidate the functions of ITIH1 and its role in human disease.

Genular Protein ID: 448896279

Symbol: ITIH1_HUMAN

Name: Inter-alpha-trypsin inhibitor heavy chain H1

UniProtKB Accession Codes:

P19827 A8K9N5 B2RAH9 B7Z558 B7Z8C0 F5H165 F5H7Y8 P78455 Q01746 Q562G1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 DrugBank 5 EMBL 27 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 9 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 2 PIR 1 PRO 1 PROSITE 2 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 RefSeq 3 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1380832

Title: Human inter-alpha-trypsin inhibitor: full-length cDNA sequence of the heavy chain H1.

PubMed ID: 1380832

DOI: 10.1016/0167-4781(92)90065-8

PubMed ID: 7505744

Title: Isolation and characterization of the human inter-alpha-trypsin inhibitor heavy-chain H1 gene.

PubMed ID: 7505744

DOI: 10.1111/j.1432-1033.1993.tb18376.x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1384548

Title: The heavy chains of human plasma inter-alpha-trypsin inhibitor: their isolation, their identification by electrophoresis and partial sequencing. Differential reactivity with concanavalin A.

PubMed ID: 1384548

DOI: 10.1515/bchm3.1992.373.2.1009

PubMed ID: 2476436

Title: Analysis of inter-alpha-trypsin inhibitor and a novel trypsin inhibitor, pre-alpha-trypsin inhibitor, from human plasma. Polypeptide chain stoichiometry and assembly by glycan.

PubMed ID: 2476436

DOI: 10.1016/s0021-9258(18)71575-5

PubMed ID: 2471637

Title: Two out of the three kinds of subunits of inter-alpha-trypsin inhibitor are structurally related.

PubMed ID: 2471637

DOI: 10.1111/j.1432-1033.1989.tb14762.x

PubMed ID: 7504674

Title: A serum-derived hyaluronan-associated protein (SHAP) is the heavy chain of the inter alpha-trypsin inhibitor.

PubMed ID: 7504674

DOI: 10.1016/s0021-9258(19)74373-7

PubMed ID: 2446322

Title: Isolation and characterization of cDNAs encoding the heavy chain of human inter-alpha-trypsin inhibitor (I alpha TI): unambiguous evidence for multipolypeptide chain structure of I alpha TI.

PubMed ID: 2446322

DOI: 10.1073/pnas.84.23.8272

PubMed ID: 3663330

Title: cDNA cloning of human inter-alpha-trypsin inhibitor discloses three different proteins.

PubMed ID: 3663330

DOI: 10.1515/bchm3.1987.368.2.963

PubMed ID: 7513643

Title: Chondroitin sulphate covalently cross-links the three polypeptide chains of inter-alpha-trypsin inhibitor.

PubMed ID: 7513643

DOI: 10.1111/j.1432-1033.1994.tb18803.x

PubMed ID: 7522574

Title: Tandem orientation of the inter-alpha-trypsin inhibitor heavy chain H1 and H3 genes.

PubMed ID: 7522574

DOI: 10.1016/0167-4781(94)90087-6

PubMed ID: 9677337

Title: Glycosylation pattern of human inter-alpha-inhibitor heavy chains.

PubMed ID: 9677337

DOI: 10.1042/bj3330749

PubMed ID: 9425062

Title: Posttranslational modifications of human inter-alpha-inhibitor: identification of glycans and disulfide bridges in heavy chains 1 and 2.

PubMed ID: 9425062

DOI: 10.1021/bi971137d

PubMed ID: 12754519

Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

PubMed ID: 12754519

DOI: 10.1038/nbt827

PubMed ID: 14760718

Title: Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.

PubMed ID: 14760718

DOI: 10.1002/pmic.200300556

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19139490

Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.

PubMed ID: 19139490

DOI: 10.1074/mcp.m800504-mcp200

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26468290

Title: Metal Ion-dependent Heavy Chain Transfer Activity of TSG-6 Mediates Assembly of the Cumulus-Oocyte Matrix.

PubMed ID: 26468290

DOI: 10.1074/jbc.m115.669838

PubMed ID: 7535743

Title: Molecular basis of inter-alpha-trypsin inhibitor heavy chain H1 (ITIH1) polymorphism.

PubMed ID: 7535743

DOI: 10.1007/bf00208970

Sequence Information:

  • Length: 911
  • Mass: 101389
  • Checksum: 8FE715FF223FC917
  • Sequence:
    • MDGAMGPRGL LLCMYLVSLL ILQAMPALGS ATGRSKSSEK RQAVDTAVDG VFIRSLKVNC 
KVTSRFAHYV VTSQVVNTAN EAREVAFDLE IPKTAFISDF AVTADGNAFI GDIKDKVTAW 
KQYRKAAISG ENAGLVRASG RTMEQFTIHL TVNPQSKVTF QLTYEEVLKR NHMQYEIVIK 
VKPKQLVHHF EIDVDIFEPQ GISKLDAQAS FLPKELAAQT IKKSFSGKKG HVLFRPTVSQ 
QQSCPTCSTS LLNGHFKVTY DVSRDKICDL LVANNHFAHF FAPQNLTNMN KNVVFVIDIS 
GSMRGQKVKQ TKEALLKILG DMQPGDYFDL VLFGTRVQSW KGSLVQASEA NLQAAQDFVR 
GFSLDEATNL NGGLLRGIEI LNQVQESLPE LSNHASILIM LTDGDPTEGV TDRSQILKNV 
RNAIRGRFPL YNLGFGHNVD FNFLEVMSME NNGRAQRIYE DHDATQQLQG FYSQVAKPLL 
VDVDLQYPQD AVLALTQNHH KQYYEGSEIV VAGRIADNKQ SSFKADVQAH GEGQEFSITC 
LVDEEEMKKL LRERGHMLEN HVERLWAYLT IQELLAKRMK VDREERANLS SQALQMSLDY 
GFVTPLTSMS IRGMADQDGL KPTIDKPSED SPPLEMLGPR RTFVLSALQP SPTHSSSNTQ 
RLPDRVTGVD TDPHFIIHVP QKEDTLCFNI NEEPGVILSL VQDPNTGFSV NGQLIGNKAR 
SPGQHDGTYF GRLGIANPAT DFQLEVTPQN ITLNPGFGGP VFSWRDQAVL RQDGVVVTIN 
KKRNLVVSVD DGGTFEVVLH RVWKGSSVHQ DFLGFYVLDS HRMSARTHGL LGQFFHPIGF 
EVSDIHPGSD PTKPDATMVV RNRRLTVTRG LQKDYSKDPW HGAEVSCWFI HNNGAGLIDG 
AYTDYIVPDI F

Genular Protein ID: 4070735544

Symbol: B7Z8B6_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z8B6

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 EMBL 2 GO 2 Gene3D 1 Genevisible 1 GenomeRNAi 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 2 RefSeq 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 623
  • Mass: 69527
  • Checksum: 60ED5DBCD93E45DA
  • Sequence:
    • MNKNVVFVID ISGSMRGQKV KQIKEALLKI LGDMQPGDYF DLVLFGTRVQ SWKGSLVQAS 
EANLQAAQDF VRGFSLDEAT NLNGGLLRGI EILNQVQESL PELSNHASIL IMLTDGDPTE 
GVTDRSQILK NVRNAIRGRF PLYNLGFGHN VDFNFLEVMS MENNGRAQRI YEDHDATQQL 
QGFYSQVAKP LLVDVDLQYP QDAVLALTQN HHKQYYEGSE IVVAGRIADN KQSSFKADVQ 
AHGEGQEFSI TCLVDEEEMK KLLRERGHML ENHVERLWAY LTIQELLAKR MKVDREVRAN 
LSSQALRMSL DYGFVTPLTS MSIRGMADQD GLKPTIDKPS EDSPPLEMLG PRRTFVLSAL 
QPSPTHSSSN TQRLPDRVTG VDTDPHFIIH VPQKEDTLCF NINEEPGVIL SLVQDPNTGF 
SVNGQLIGNK ARSPGQHDGT YFGRLGIANP ATDFQLEVTP QNITLNPGFG GPVFSWRDQA 
VLRQDGVVVT INKKRNLVVS VYDGGTFEVV LHRVWKGSSV HQDFLGFYVL DSHRMSARTH 
GLLGQFFHPI GFEVSDIHPG SDPTKPDATM VVRSRRLTVT RGLQKDYSKD PWHGAEVSCW 
FIHNNGAGLI DGAYTDYIVP DIF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.