Details for: ITPKB
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 140.3450
Cell Significance Index: -21.8300 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 84.2521
Cell Significance Index: -21.3700 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 42.6723
Cell Significance Index: -21.9500 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 18.1109
Cell Significance Index: -22.3300 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 8.8002
Cell Significance Index: -19.2600 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 7.6786
Cell Significance Index: -20.5700 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 7.4590
Cell Significance Index: -22.9100 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: 5.8426
Cell Significance Index: 81.7000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 5.7196
Cell Significance Index: -22.5700 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 3.1003
Cell Significance Index: 44.5900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 2.3916
Cell Significance Index: 1085.4700 - Cell Name: mature astrocyte (CL0002627)
Fold Change: 1.6198
Cell Significance Index: 18.0000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.1039
Cell Significance Index: 114.9400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.7928
Cell Significance Index: 1492.7400 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: 0.7878
Cell Significance Index: 4.7600 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: 0.7859
Cell Significance Index: 7.8800 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4783
Cell Significance Index: 47.3200 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.4206
Cell Significance Index: 379.8100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.3890
Cell Significance Index: 45.8700 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: 0.3389
Cell Significance Index: 5.8600 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: 0.3041
Cell Significance Index: 2.4800 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.2840
Cell Significance Index: 17.0500 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.2758
Cell Significance Index: 30.0000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.2641
Cell Significance Index: 42.9600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.2367
Cell Significance Index: 150.3200 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.2362
Cell Significance Index: 5.0300 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.2026
Cell Significance Index: 3.2500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.1506
Cell Significance Index: 7.0200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1331
Cell Significance Index: 23.9900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0917
Cell Significance Index: 17.4600 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0912
Cell Significance Index: 2.2800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0847
Cell Significance Index: 37.4700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0729
Cell Significance Index: 14.6200 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0514
Cell Significance Index: 35.5700 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0265
Cell Significance Index: 14.5000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0042
Cell Significance Index: 1.4900 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0037
Cell Significance Index: -6.7700 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0088
Cell Significance Index: -6.4300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0090
Cell Significance Index: -13.8900 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0130
Cell Significance Index: -1.6800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0141
Cell Significance Index: -19.2100 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.0168
Cell Significance Index: -0.3600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0247
Cell Significance Index: -3.3900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0266
Cell Significance Index: -20.1600 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0274
Cell Significance Index: -0.7900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0332
Cell Significance Index: -24.5800 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0378
Cell Significance Index: -0.8200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0387
Cell Significance Index: -24.1800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0439
Cell Significance Index: -24.7700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0496
Cell Significance Index: -6.1000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0548
Cell Significance Index: -7.9700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0650
Cell Significance Index: -12.8900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.0672
Cell Significance Index: -4.6500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0701
Cell Significance Index: -20.1600 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0710
Cell Significance Index: -3.2200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0776
Cell Significance Index: -2.1700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0848
Cell Significance Index: -5.4700 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0957
Cell Significance Index: -12.2700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0982
Cell Significance Index: -16.7700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1178
Cell Significance Index: -24.8200 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1200
Cell Significance Index: -13.9800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1363
Cell Significance Index: -13.9300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1406
Cell Significance Index: -4.9400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1579
Cell Significance Index: -7.4200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1769
Cell Significance Index: -20.2700 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1779
Cell Significance Index: -13.6600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1801
Cell Significance Index: -11.0400 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.2011
Cell Significance Index: -10.1600 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.2165
Cell Significance Index: -6.2100 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.2186
Cell Significance Index: -3.1300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2321
Cell Significance Index: -17.3000 - Cell Name: astrocyte (CL0000127)
Fold Change: -0.2324
Cell Significance Index: -2.6600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2331
Cell Significance Index: -18.4600 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.2388
Cell Significance Index: -16.8900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.2420
Cell Significance Index: -16.2700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.2720
Cell Significance Index: -14.1300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.2837
Cell Significance Index: -15.9200 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.2862
Cell Significance Index: -17.5900 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.2888
Cell Significance Index: -3.9400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3272
Cell Significance Index: -10.4800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3671
Cell Significance Index: -23.1400 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.4155
Cell Significance Index: -11.3100 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.4222
Cell Significance Index: -8.2400 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.4293
Cell Significance Index: -18.9900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.4416
Cell Significance Index: -23.1900 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: -0.4915
Cell Significance Index: -5.2700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.5094
Cell Significance Index: -19.2900 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.5293
Cell Significance Index: -19.4300 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.5422
Cell Significance Index: -8.1700 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.5530
Cell Significance Index: -14.5400 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.5605
Cell Significance Index: -9.3800 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.5830
Cell Significance Index: -20.2600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.5831
Cell Significance Index: -19.0900 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.5836
Cell Significance Index: -17.1400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.5909
Cell Significance Index: -15.1900 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.6072
Cell Significance Index: -21.2700 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.6467
Cell Significance Index: -17.3000 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.6605
Cell Significance Index: -13.2600 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.6675
Cell Significance Index: -21.2600 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: -0.6701
Cell Significance Index: -10.2000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1245149731
Symbol: IP3KB_HUMAN
Name: Inositol 1,4,5-trisphosphate 3-kinase B
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11846419
Title: Cloning and expression of a full-length cDNA encoding human inositol 1,4,5-trisphosphate 3-kinase B.
PubMed ID: 11846419
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1654894
Title: Molecular cloning and expression of a new putative inositol 1,4,5-trisphosphate 3-kinase isoenzyme.
PubMed ID: 1654894
DOI: 10.1042/bj2780883
PubMed ID: 12747803
Title: The three isoenzymes of human inositol-1,4,5-trisphosphate 3-kinase show specific intracellular localization but comparable Ca2+ responses on transfection in COS-7 cells.
PubMed ID: 12747803
DOI: 10.1042/bj20021963
PubMed ID: 18088087
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 23060452
Title: Headpiece domain of dematin regulates calcium mobilization and signaling in platelets.
PubMed ID: 23060452
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 946
- Mass: 102376
- Checksum: 2CCBCBE7AEF26848
- Sequence:
MAVYCYALNS LVIMNSANEM KSGGGPGPSG SETPPPPRRA VLSPGSVFSP GRGASFLFPP AESLSPEEPR SPGGWRSGRR RLNSSSGSGS GSSGSSVSSP SWAGRLRGDR QQVVAAGTLS PPGPEEAKRK LRILQRELQN VQVNQKVGMF EAHIQAQSSA IQAPRSPRLG RARSPSPCPF RSSSQPPGRV LVQGARSEER RTKSWGEQCP ETSGTDSGRK GGPSLCSSQV KKGMPPLPGR AAPTGSEAQG PSAFVRMEKG IPASPRCGSP TAMEIDKRGS PTPGTRSCLA PSLGLFGASL TMATEVAARV TSTGPHRPQD LALTEPSGRA RELEDLQPPE ALVERQGQFL GSETSPAPER GGPRDGEPPG KMGKGYLPCG MPGSGEPEVG KRPEETTVSV QSAESSDSLS WSRLPRALAS VGPEEARSGA PVGGGRWQLS DRVEGGSPTL GLLGGSPSAQ PGTGNVEAGI PSGRMLEPLP CWDAAKDLKE PQCPPGDRVG VQPGNSRVWQ GTMEKAGLAW TRGTGVQSEG TWESQRQDSD ALPSPELLPQ DPDKPFLRKA CSPSNIPAVI ITDMGTQEDG ALEETQGSPR GNLPLRKLSS SSASSTGFSS SYEDSEEDIS SDPERTLDPN SAFLHTLDQQ KPRVSKSWRK IKNMVHWSPF VMSFKKKYPW IQLAGHAGSF KAAANGRILK KHCESEQRCL DRLMVDVLRP FVPAYHGDVV KDGERYNQMD DLLADFDSPC VMDCKMGIRT YLEEELTKAR KKPSLRKDMY QKMIEVDPEA PTEEEKAQRA VTKPRYMQWR ETISSTATLG FRIEGIKKED GTVNRDFKKT KTREQVTEAF REFTKGNHNI LIAYRDRLKA IRTTLEVSPF FKCHEVIGSS LLFIHDKKEQ AKVWMIDFGK TTPLPEGQTL QHDVPWQEGN REDGYLSGLN NLVDILTEMS QDAPLA
Genular Protein ID: 949580081
Symbol: B2R9J0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 472
- Mass: 53500
- Checksum: 576E47E46AAC1A29
- Sequence:
MLEPLPCWDA AKDLKEPQCP PGDRVGVQPG NSRVWQGTME KAGLAWTRGT GVQSEGTWES QRQDSDALPS PELLPQDQDK PFLRKACSPS NIPAVIITDM GTQEDGALEE TQGSPRGNLP LRKLSSSSAS STGFSSSYED SEEDISSDPE RTLDPNSAFL HTLDQQKPRV SKSWRKIKNM VHWSPFVMSF KKKYPWIQLA GHAGSFKAAA NGRILKKHCE SEQRCLDRLM VDVLRPFVPA YHGDVVKDGE RYNQMDDLLA DFDSPCVMDC KMGIRTYLEE ELTKARRKPS LRKDMYQKMI EVDPEAPTEE EKAQRAVTKP RYMQWRETIS STATLGFRIE GIKKEDGTVN RDFKKTKTRE QVTEAFREFT KGNHNILIAY RDRLKAIRTT LEVSPFFKCH EVIGSSLLFI HDKKEQAKVW MIDFGKTTPL PEGQTLQHDV PWQEGNREDG YLSGLNNLVD ILTEMSQDAP LA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.