Details for: ITPR3

Gene ID: 3710

Symbol: ITPR3

Ensembl ID: ENSG00000096433

Description: inositol 1,4,5-trisphosphate receptor type 3

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 2.04
    Marker Score: 2254
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 1.52
    Marker Score: 9693
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 1.41
    Marker Score: 2274
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 1.38
    Marker Score: 22150
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 1.34
    Marker Score: 895
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 1.32
    Marker Score: 5517
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.31
    Marker Score: 781
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 1.3
    Marker Score: 8502
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.17
    Marker Score: 1189
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 1.15
    Marker Score: 4469
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 1.15
    Marker Score: 5641
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 1.12
    Marker Score: 8329
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 1.11
    Marker Score: 5820
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 1.11
    Marker Score: 3473
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.1
    Marker Score: 17175
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: 1.04
    Marker Score: 2546
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 1
    Marker Score: 767
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71761
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47985
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.99
    Marker Score: 1045
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 0.98
    Marker Score: 1225
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30402
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.95
    Marker Score: 489
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.95
    Marker Score: 570
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2404
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.94
    Marker Score: 444
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 0.94
    Marker Score: 270
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.92
    Marker Score: 5268
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2718
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 0.9
    Marker Score: 2045
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.9
    Marker Score: 1456
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 0.89
    Marker Score: 838
  • Cell Name: mammary gland epithelial cell (CL0002327)
    Fold Change: 0.88
    Marker Score: 312
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: 0.88
    Marker Score: 433
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.87
    Marker Score: 313
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5261
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.87
    Marker Score: 1760
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.86
    Marker Score: 214
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 0.84
    Marker Score: 4043
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.84
    Marker Score: 375
  • Cell Name: stem cell (CL0000034)
    Fold Change: 0.83
    Marker Score: 1981.5
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.82
    Marker Score: 256
  • Cell Name: type I pneumocyte (CL0002062)
    Fold Change: 0.81
    Marker Score: 981
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 0.81
    Marker Score: 353
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.81
    Marker Score: 4846
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.79
    Marker Score: 785
  • Cell Name: intestine goblet cell (CL0019031)
    Fold Change: 0.78
    Marker Score: 752
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.77
    Marker Score: 869
  • Cell Name: basal cell (CL0000646)
    Fold Change: 0.76
    Marker Score: 984
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.76
    Marker Score: 817
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 0.76
    Marker Score: 750
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.74
    Marker Score: 381
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 0.73
    Marker Score: 1167
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.73
    Marker Score: 292
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 0.72
    Marker Score: 398
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.71
    Marker Score: 571
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 0.69
    Marker Score: 323
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.69
    Marker Score: 629
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.69
    Marker Score: 2041
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.67
    Marker Score: 172
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.67
    Marker Score: 296
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 0.65
    Marker Score: 701
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.65
    Marker Score: 2717
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.64
    Marker Score: 1116
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 0.62
    Marker Score: 234
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 0.62
    Marker Score: 178
  • Cell Name: club cell (CL0000158)
    Fold Change: 0.62
    Marker Score: 719
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 0.61
    Marker Score: 467
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.6
    Marker Score: 533
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 0.59
    Marker Score: 216
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.59
    Marker Score: 20337
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 0.59
    Marker Score: 329
  • Cell Name: pulmonary ionocyte (CL0017000)
    Fold Change: 0.58
    Marker Score: 358
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.58
    Marker Score: 19813
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 0.58
    Marker Score: 1053
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.54
    Marker Score: 144
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.54
    Marker Score: 433
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.53
    Marker Score: 362
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.53
    Marker Score: 170
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.53
    Marker Score: 151
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.53
    Marker Score: 336
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.52
    Marker Score: 540
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.52
    Marker Score: 1782
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: 0.52
    Marker Score: 496
  • Cell Name: Unknown (CL0000548)
    Fold Change: 0.52
    Marker Score: 377
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.51
    Marker Score: 456
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: 0.51
    Marker Score: 129
  • Cell Name: precursor cell (CL0011115)
    Fold Change: 0.5
    Marker Score: 122
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.5
    Marker Score: 239
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: 0.49
    Marker Score: 484
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 0.49
    Marker Score: 619
  • Cell Name: M cell of gut (CL0000682)
    Fold Change: 0.49
    Marker Score: 128
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 0.48
    Marker Score: 686
  • Cell Name: ionocyte (CL0005006)
    Fold Change: 0.48
    Marker Score: 146
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 0.47
    Marker Score: 95
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.47
    Marker Score: 121
  • Cell Name: endothelial cell of artery (CL1000413)
    Fold Change: 0.47
    Marker Score: 193
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.46
    Marker Score: 2733.5
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.46
    Marker Score: 550
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 0.45
    Marker Score: 120

Hover over a box to see details here...

Hover over a box to see details here...

Hover over a box to see details here...

Other Information

**Key characteristics** * ITPR3 is a type of receptor that is involved in the second messenger signaling pathway. * It is expressed in a variety of cell types, including immune cells, cardiac cells, and endothelial cells. * It is a key regulator of immune responses, cardiac function, and blood pressure. **Pathways and functions** * ITPR3 is involved in the regulation of the adaptive immune system. It is expressed on antigen-presenting cells, such as dendritic cells, and is important for the activation of T cells. * ITPR3 is also involved in the regulation of cardiac conduction. It is expressed in heart muscle cells and is important for the maintenance of cardiac rhythm. * ITPR3 is involved in the regulation of blood pressure. It is expressed in blood vessels and is important for the regulation of blood pressure. **Clinical significance** ITPR3 is a gene that is linked to a number of human diseases, including asthma, rheumatoid arthritis, and lupus. Mutations in ITPR3 have been linked to these diseases, and inhibitors of ITPR3 have been shown to be effective in treating these diseases. **Additional information** * ITPR3 is a member of the inositol 1,4,5-trisphosphate receptor family of proteins. * It is a highly conserved protein, with a similar sequence in mice and humans. * ITPR3 is a relatively new protein, with the first human sequence being published in 2000.

Genular Protein ID: 2184404245

Symbol: ITPR3_HUMAN

Name: Inositol 1,4,5-trisphosphate receptor type 3

UniProtKB Accession Codes:

Q14573 Q14649 Q5TAQ2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChEBI 3 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 4 EMDB 15 EPD 1 Ensembl 2 GO 35 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 15 PDBsum 15 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 15 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8081734

Title: Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors.

PubMed ID: 8081734

PubMed ID: 8288584

Title: Primary structure, ligand binding, and localization of the human type 3 inositol 1,4,5-trisphosphate receptor expressed in intestinal epithelium.

PubMed ID: 8288584

DOI: 10.1016/s0021-9258(17)42246-0

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 12032348

Title: Identification of a family of calcium sensors as protein ligands of inositol trisphosphate receptor Ca(2+) release channels.

PubMed ID: 12032348

DOI: 10.1073/pnas.102006299

PubMed ID: 18826956

Title: IP3 receptor binds to and sensitizes TRPV4 channel to osmotic stimuli via a calmodulin-binding site.

PubMed ID: 18826956

DOI: 10.1074/jbc.c800184200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19553469

Title: Human Golgi antiapoptotic protein modulates intracellular calcium fluxes.

PubMed ID: 19553469

DOI: 10.1091/mbc.e09-05-0385

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 23936024

Title: Early insights into the function of KIAA1199, a markedly overexpressed protein in human colorectal tumors.

PubMed ID: 23936024

DOI: 10.1371/journal.pone.0069473

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25996873

Title: TMEM203 is a novel regulator of intracellular calcium homeostasis and is required for spermatogenesis.

PubMed ID: 25996873

DOI: 10.1371/journal.pone.0127480

PubMed ID: 27995898

Title: IRBIT controls apoptosis by interacting with the Bcl-2 homolog, Bcl2l10, and by promoting ER-mitochondria contact.

PubMed ID: 27995898

DOI: 10.7554/elife.19896

PubMed ID: 24627108

Title: Whole-exome sequencing in patients with inherited neuropathies: outcome and challenges.

PubMed ID: 24627108

DOI: 10.1007/s00415-014-7289-8

PubMed ID: 32949214

Title: Dominant mutations in ITPR3 cause Charcot-Marie-Tooth disease.

PubMed ID: 32949214

DOI: 10.1002/acn3.51190

Sequence Information:

  • Length: 2671
  • Mass: 304106
  • Checksum: 04D1957A53320EEE
  • Sequence:
    • MSEMSSFLHI GDIVSLYAEG SVNGFISTLG LVDDRCVVEP AAGDLDNPPK KFRDCLFKVC 
PMNRYSAQKQ YWKAKQTKQD KEKIADVVLL QKLQHAAQME QKQNDTENKK VHGDVVKYGS 
VIQLLHMKSN KYLTVNKRLP ALLEKNAMRV TLDATGNEGS WLFIQPFWKL RSNGDNVVVG 
DKVILNPVNA GQPLHASNYE LSDNAGCKEV NSVNCNTSWK INLFMQFRDH LEEVLKGGDV 
VRLFHAEQEK FLTCDEYKGK LQVFLRTTLR QSATSATSSN ALWEVEVVHH DPCRGGAGHW 
NGLYRFKHLA TGNYLAAEEN PSYKGDASDP KAAGMGAQGR TGRRNAGEKI KYCLVAVPHG 
NDIASLFELD PTTLQKTDSF VPRNSYVRLR HLCTNTWIQS TNVPIDIEEE RPIRLMLGTC 
PTKEDKEAFA IVSVPVSEIR DLDFANDASS MLASAVEKLN EGFISQNDRR FVIQLLEDLV 
FFVSDVPNNG QNVLDIMVTK PNRERQKLMR EQNILKQVFG ILKAPFREKG GEGPLVRLEE 
LSDQKNAPYQ HMFRLCYRVL RHSQEDYRKN QEHIAKQFGM MQSQIGYDIL AEDTITALLH 
NNRKLLEKHI TKTEVETFVS LVRKNREPRF LDYLSDLCVS NHIAIPVTQE LICKCVLDPK 
NSDILIRTEL RPVKEMAQSH EYLSIEYSEE EVWLTWTDKN NEHHEKSVRQ LAQEARAGNA 
HDENVLSYYR YQLKLFARMC LDRQYLAIDE ISQQLGVDLI FLCMADEMLP FDLRASFCHL 
MLHVHVDRDP QELVTPVKFA RLWTEIPTAI TIKDYDSNLN ASRDDKKNKF ANTMEFVEDY 
LNNVVSEAVP FANEEKNKLT FEVVSLAHNL IYFGFYSFSE LLRLTRTLLG IIDCVQGPPA 
MLQAYEDPGG KNVRRSIQGV GHMMSTMVLS RKQSVFSAPS LSAGASAAEP LDRSKFEENE 
DIVVMETKLK ILEILQFILN VRLDYRISYL LSVFKKEFVE VFPMQDSGAD GTAPAFDSTT 
ANMNLDRIGE QAEAMFGVGK TSSMLEVDDE GGRMFLRVLI HLTMHDYAPL VSGALQLLFK 
HFSQRQEAMH TFKQVQLLIS AQDVENYKVI KSELDRLRTM VEKSELWVDK KGSGKGEEVE 
AGAAKDKKER PTDEEGFLHP PGEKSSENYQ IVKGILERLN KMCGVGEQMR KKQQRLLKNM 
DAHKVMLDLL QIPYDKGDAK MMEILRYTHQ FLQKFCAGNP GNQALLHKHL HLFLTPGLLE 
AETMQHIFLN NYQLCSEISE PVLQHFVHLL ATHGRHVQYL DFLHTVIKAE GKYVKKCQDM 
IMTELTNAGD DVVVFYNDKA SLAHLLDMMK AARDGVEDHS PLMYHISLVD LLAACAEGKN 
VYTEIKCTSL LPLEDVVSVV THEDCITEVK MAYVNFVNHC YVDTEVEMKE IYTSNHIWTL 
FENFTLDMAR VCSKREKRVA DPTLEKYVLS VVLDTINAFF SSPFSENSTS LQTHQTIVVQ 
LLQSTTRLLE CPWLQQQHKG SVEACIRTLA MVAKGRAILL PMDLDAHISS MLSSGASCAA 
AAQRNASSYK ATTRAFPRVT PTANQWDYKN IIEKLQDIIT ALEERLKPLV QAELSVLVDV 
LHWPELLFLE GSEAYQRCES GGFLSKLIQH TKDLMESEEK LCIKVLRTLQ QMLLKKTKYG 
DRGNQLRKML LQNYLQNRKS TSRGDLPDPI GTGLDPDWSA IAATQCRLDK EGATKLVCDL 
ITSTKNEKIF QESIGLAIHL LDGGNTEIQK SFHNLMMSDK KSERFFKVLH DRMKRAQQET 
KSTVAVNMND LGSQPHEDRE PVDPTTKGRV ASFSIPGSSS RYSLGPSLRR GHEVSERVQS 
SEMGTSVLIM QPILRFLQLL CENHNRDLQN FLRCQNNKTN YNLVCETLQF LDIMCGSTTG 
GLGLLGLYIN EDNVGLVIQT LETLTEYCQG PCHENQTCIV THESNGIDII TALILNDISP 
LCKYRMDLVL QLKDNASKLL LALMESRHDS ENAERILISL RPQELVDVIK KAYLQEEERE 
NSEVSPREVG HNIYILALQL SRHNKQLQHL LKPVKRIQEE EAEGISSMLS LNNKQLSQML 
KSSAPAQEEE EDPLAYYENH TSQIEIVRQD RSMEQIVFPV PGICQFLTEE TKHRLFTTTE 
QDEQGSKVSD FFDQSSFLHN EMEWQRKLRS MPLIYWFSRR MTLWGSISFN LAVFINIIIA 
FFYPYMEGAS TGVLDSPLIS LLFWILICFS IAALFTKRYS IRPLIVALIL RSIYYLGIGP 
TLNILGALNL TNKIVFVVSF VGNRGTFIRG YKAMVMDMEF LYHVGYILTS VLGLFAHELF 
YSILLFDLIY REETLFNVIK SVTRNGRSIL LTALLALILV YLFSIVGFLF LKDDFILEVD 
RLPNNHSTAS PLGMPHGAAA FVDTCSGDKM DCVSGLSVPE VLEEDRELDS TERACDTLLM 
CIVTVMNHGL RNGGGVGDIL RKPSKDESLF PARVVYDLLF FFIVIIIVLN LIFGVIIDTF 
ADLRSEKQKK EEILKTTCFI CGLERDKFDN KTVSFEEHIK LEHNMWNYLY FIVLVRVKNK 
TDYTGPESYV AQMIKNKNLD WFPRMRAMSL VSNEGEGEQN EIRILQDKLN STMKLVSHLT 
AQLNELKEQM TEQRKRRQRL GFVDVQNCIS R

Genular Protein ID: 2013760648

Symbol: A6H8K3_HUMAN

Name: N/A

UniProtKB Accession Codes:

A6H8K3

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 3 Gene3D 2 Genevisible 1 GenomeRNAi 1 InterPro 7 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 1 RuleBase 1 SAM 1 SMART 1 SUPFAM 2

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1049
  • Mass: 119214
  • Checksum: BF4224180E6C031A
  • Sequence:
    • MSEMSSFLHI GDIVSLYAEG SVNGFISTLG LVDDRCVVEP AAGDLDNPPK KFRDCLFKVC 
PMNRYSAQKQ YWKAKQTKQD KEKIADVVLL QKLQHAAQME QKQNDTENKK VHGDVVKYGS 
VIQLLHMKSN KYLTVNKRLP ALLEKNAMRV TLDATGNEGS WLFIQPFWKL RSNGDNVVVG 
DKVILNPVNA GQPLHASNYE LSDNAGCKEV NSVNCNTSWK INLFMQFRDH LEEVLKGGDV 
VRLFHAEQEK FLTCDEYKGK LQVFLRTTLR QSATSATSSN ALWEVEVVHH DPCRGGAGHW 
NGLYRFKHLA TGNYLAAEEN PSYKGDASDP KAAGMGAQGR TGRRNAGEKI KYCLVAVPHG 
NDIASLFELD PTTLQKTDSF VPRNSYVRLR HLCTNTWIQS TNVPIDIEEE RPIRLMLGTC 
PTKEDKEAFA IVSVPVSEIR DLDFANDASS MLASAVEKLN EGFISQNDRR FVIQLLEDLV 
FFVSDVPNNG QNVLDIMVTK PNRERQKLMR EQNILKQVFG ILKAPFREKG GEGPLVRLEE 
LSDQKNAPYQ HMFRLCYRVL RHSQEDYRKN QEHIAKQFGM MQSQIGYDIL AEDTITALLH 
NNRKLLEKHI TKTEVETFVS LVRKNREPRF LDYLSDLCVS NHIAIPVTQE LICKCVLDPK 
NSDILIRTEL RPVKEMAQSH EYLSIEYSEE EVWLTWTDKN NEHHEKSVRQ LAQEARAGNA 
HDENVLSYYR YQLKLFARMC LDRQYLAIDE ISQQLGVDLI FLCMADEMLP FDLRASFCHL 
MLHVHVDRDP QELVTPVKFA RLWTEIPTAI TIKDYDSNLN ASRDDKKNKF ANTMEFVEDY 
LNNVVSEAVP FANEEKNKLT FEVVSLAHNL IYFGFYSFSE LLRLTRTLLG IIDCVQGPPA 
MLQAYEDPGG KNVRRSIQGV GHMMSTMVLS RKQSVFSAPS LSAGASAAEP LDRSKFEENE 
DIVVMETKLK ILEILQFILN VRLDYRISYL LSVFKKEFVE VFPMQDSGAD GTAPAFDSTT 
ANMNLDRIGE QAEAMFGVGK TSSMLEVDD

Genular Protein ID: 4213262244

Symbol: Q59ES2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59ES2

Database IDs:

ARBA 9 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 2 Gene3D 3 Genevisible 1 GenomeRNAi 1 InterPro 7 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 8 PharmGKB 1 RefSeq 1 SAM 3 SUPFAM 2

Sequence Information:

  • Length: 2341
  • Mass: 267023
  • Checksum: 21E4BF7271409D83
  • Sequence:
    • KAAGMGAQGR TGRRNAGEKI KYCLVAVPHG NDIASLFELD PTTLQKTDSF VPRNSYVRLR 
HLCTNTWIQS TNVPIDIEEE RPIRLMLGTC PTKEDKEAFA IVSVPVSEIR DLDFANDASS 
MLASAVEKLN EGFISQNDRR FVIQLLEDLV FFVSDVPNNG QNVLDIMVTK PNRERQKLMR 
EQNILKQVFG ILKAPFREKG GEGPLVRLEE LSDQKNAPYQ HMFRLCYRVL RHSQEDYRKN 
QEHIAKQFGM MQSQIGYDIL AEDTITALLH NNRKLLEKHI TKTEVETFVS LVRKNREPRF 
LDYLSDLCVS NHIAIPVTQE LICKCVLDPK NSDILIRTEL RPVKEMAQSH EYLSIEYSEE 
EVWLTWTDKN NEHHEKSVRQ LAQEARAGNA HDENVLSYYR YQLKLFARMC LDRQYLAIDE 
ISQQLGVDLI FLCMADEMLP FDLRASFCHL MLHVHVDRDP QELVTPVKFA RLWTEIPTAI 
TIKDYDSNLN ASRDDKKNKF ANTMEFVEDY LNNVVSEAVP FANEEKNKLT FEVVSLAHNL 
IYFGFYSFSE LLRLTRTLLG IIDCVQGPPA MLQAYEDPGG KNVRRSIQGV GHMMSTMVLS 
RKQSVFSAPS LSAGASAAEP LDRSKFEENE DIVVMETKLK ILEILQFILN VRLDYRISYL 
LSVFKKEFVE VFPMQDSGAD GTASAFDSTT ANMNLDRIGE QAEAMFGVGK TSSMLEVDDE 
GGRMFLRVLI HLTMHDYAPL VSGALQLLFK HFSQRQEAMH TFKQVQLLIS AQDVENYKVI 
KSELDRLRTM VEKSELWVDK KGSGKGEEVE AGAAKDKKER PTDEEGFLHP PGEKSSENYQ 
IVKGILERLN KMCGVGEQMR KKQQRLLKNM DAHKVMLDLL QIPYDKGDAK MMEILRYTHQ 
FLQKFCAGNP GNQALLHKHL HLFLTPGLLE AETMQHIFLN NYQLCSEISE PVLQHFVHLL 
ATHGRHVQYL DFLHTVIKAE GKYVKKCQDM IMTELTNAGD DVVVFYNDKA SLAHLLDMMK 
AARDGVEDHS PLMYHISLVD LLAACAEGKN VYTEIKCTSL LPLEDVVSVV THEDCITEVK 
MAYVNFVNHC YVDTEVEMKE IYTSNHIWTL FENFTLDMAR VCSKREKRVA DPTLEKYVLS 
VVLDTINAFF SSPFSENSTS LQTHQTIVVQ LLQSTTRLLE CPWLQQQHKG SVEACIRTLA 
MVAKGRAILL PMDLDAHISS MLSSGASCAA AAQRNASSYK ATTRAFPRVT PTANQWDYKN 
IIEKLQDIIT ALEERLKPLV QAELSVLVDV LHWPELLFLE GSEAYQRCES GGFLSKLIQH 
TKDLMESEEK LCIKVLRTLQ QMLLKKTKYG DRGNQLRKML LQNYLQNRKS TSRGDLPDPI 
GTGLDPDWSA IAATQCRLDK EGATKLVCDL ITSTKNEKIF QESIGLAIHL LDGGNTEIQK 
SFHNLMMSDK KSERFFKVLH DRMKRAQQET KSTVAVNMND LGSQPHEDRE PVDPTTKGRV 
ASFSIPGSSS RYSLGPSLRR GHEVSERVQS SEMGTSVLIM QPILRFLQLL CENHNRDLQN 
FLRCQNNKTN YNLVCETLQF LDIMCGSTTG GLGLLGLYIN EDNVGLVIQT LETLTEYCQG 
PCHENQTCIV THESNGIDII TALILNDISP LCKYRMDLVL QLKDNASKLL LALMESRHDS 
ENAERILISL RPQELVDVIK KAYLQEEERE NSEVSPREVG HNIYILALQL SRHNKQLQHL 
LKPVKRIQEE EAEGISSMLS LNNKQLSQML KSSAPAQEEE EDPLAYYENH TSQIEIVRQD 
RSMEQIVFPV PGICQFLTEE TKHRLFTTTE QDEQGSKVSD FFDQSSFLHN EMEWQRKLRS 
MPLIYWFSRR MTLWGSISFN LAVFINIIIA FFYPYMEGAS TGVLDSPLIS LLFWILICFS 
IAALFTKRYS IRPLIVALIL RSIYYLGIGP TLNILGALNL TNKIVFVVSF VGNRGTFIRG 
YKAMVMDMEF LYHVGYILTS VLGLFAHELF YSILLFDLIY REETLFNVIK SVTRNGRSIL 
LTALLALILV YLFSIVGFLF LKDDFILEVD RLPNNHSTAS PLGMPHGAAA FVDTCSGDKM 
DCVSGLSVPE VLEEDRELDS TERACDTLLM CIVTVMNHGL RNGGGVGDIL RKPSKDESLF 
PARVVYDLLF FFIVIIIVLN LIFGVIIDTF ADLRSEKQKK EEILKTTCFI CGLERDKFDN 
KTVSFEEHIK LEHNMWNYLY FIVLVRVKNK TDYTGPESYV AQMIKNKNLD WFPRMRAMSL 
VSNEGEGEQN EIRILQDKLN STMKLVSHLT AQLNELKEQM TEQRKRRQRL GFVDVQNCIS 
R

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.