Details for: KIR3DL2

Gene ID: 3812

Symbol: KIR3DL2

Ensembl ID: ENSG00000240403

Description: killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: suprabasal keratinocyte (CL4033013)
    Fold Change: 1.6580
    Cell Significance Index: 26.6600
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: 1.1684
    Cell Significance Index: 3.1300
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 0.5682
    Cell Significance Index: 6.3500
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 0.2989
    Cell Significance Index: 4.5400
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.1447
    Cell Significance Index: 1.7100
  • Cell Name: CD8-alpha alpha positive, gamma-delta intraepithelial T cell (CL0000802)
    Fold Change: 0.1173
    Cell Significance Index: 0.6800
  • Cell Name: activated type II NK T cell (CL0000931)
    Fold Change: 0.1016
    Cell Significance Index: 0.2600
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.0930
    Cell Significance Index: 1.2800
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: 0.0062
    Cell Significance Index: 0.2600
  • Cell Name: activated CD8-positive, alpha-beta T cell, human (CL0001049)
    Fold Change: 0.0052
    Cell Significance Index: 0.0400
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: 0.0034
    Cell Significance Index: 0.0300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0004
    Cell Significance Index: -0.6900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0006
    Cell Significance Index: -0.9100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0008
    Cell Significance Index: -1.0500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0009
    Cell Significance Index: -1.7000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0024
    Cell Significance Index: -1.7800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0028
    Cell Significance Index: -0.1400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0032
    Cell Significance Index: -1.1600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0033
    Cell Significance Index: -2.1000
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: -0.0037
    Cell Significance Index: -0.0200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0043
    Cell Significance Index: -1.9600
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.0054
    Cell Significance Index: -0.0500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0070
    Cell Significance Index: -1.3900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0084
    Cell Significance Index: -1.6900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0092
    Cell Significance Index: -1.2700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0101
    Cell Significance Index: -1.1900
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: -0.0108
    Cell Significance Index: -0.1200
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.0110
    Cell Significance Index: -0.1500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0112
    Cell Significance Index: -1.4500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0118
    Cell Significance Index: -2.1200
  • Cell Name: effector memory CD8-positive, alpha-beta T cell, terminally differentiated (CL0001062)
    Fold Change: -0.0138
    Cell Significance Index: -0.1100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0140
    Cell Significance Index: -2.0400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0152
    Cell Significance Index: -0.7100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0162
    Cell Significance Index: -1.9900
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0171
    Cell Significance Index: -0.2900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0192
    Cell Significance Index: -1.4300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0194
    Cell Significance Index: -0.9100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0202
    Cell Significance Index: -2.0600
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.0212
    Cell Significance Index: -0.3100
  • Cell Name: blood cell (CL0000081)
    Fold Change: -0.0246
    Cell Significance Index: -0.2100
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.0260
    Cell Significance Index: -0.3700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0272
    Cell Significance Index: -0.3900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0295
    Cell Significance Index: -0.7900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0307
    Cell Significance Index: -1.7300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0326
    Cell Significance Index: -2.1000
  • Cell Name: gamma-delta T cell (CL0000798)
    Fold Change: -0.0381
    Cell Significance Index: -0.3800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0411
    Cell Significance Index: -1.4400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0430
    Cell Significance Index: -1.9000
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: -0.0451
    Cell Significance Index: -0.5000
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0456
    Cell Significance Index: -1.1100
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0479
    Cell Significance Index: -1.2200
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.0485
    Cell Significance Index: -0.6000
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.0495
    Cell Significance Index: -0.5900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0498
    Cell Significance Index: -1.3300
  • Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
    Fold Change: -0.0499
    Cell Significance Index: -0.5500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0507
    Cell Significance Index: -1.9200
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.0507
    Cell Significance Index: -0.7100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0509
    Cell Significance Index: -1.4600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0512
    Cell Significance Index: -1.6300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0516
    Cell Significance Index: -1.6900
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0516
    Cell Significance Index: -0.8900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.0552
    Cell Significance Index: -1.6200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0564
    Cell Significance Index: -1.1000
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0590
    Cell Significance Index: -1.4400
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.0609
    Cell Significance Index: -0.7100
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.0628
    Cell Significance Index: -1.4500
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0642
    Cell Significance Index: -1.0300
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.0663
    Cell Significance Index: -0.9100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0690
    Cell Significance Index: -1.7200
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0692
    Cell Significance Index: -1.3800
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0700
    Cell Significance Index: -1.4600
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.0718
    Cell Significance Index: -1.4600
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0724
    Cell Significance Index: -1.8500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0729
    Cell Significance Index: -1.2500
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0735
    Cell Significance Index: -1.0900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.0742
    Cell Significance Index: -1.2500
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.0766
    Cell Significance Index: -1.2400
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.0781
    Cell Significance Index: -0.8800
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.0826
    Cell Significance Index: -1.4600
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.0842
    Cell Significance Index: -1.4400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0845
    Cell Significance Index: -1.8500
  • Cell Name: immature NK T cell (CL0000914)
    Fold Change: -0.0852
    Cell Significance Index: -1.0900
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0856
    Cell Significance Index: -1.8500
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0858
    Cell Significance Index: -1.1100
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0859
    Cell Significance Index: -1.6800
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0860
    Cell Significance Index: -1.2700
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.0880
    Cell Significance Index: -1.0700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0881
    Cell Significance Index: -1.8700
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: -0.0886
    Cell Significance Index: -0.8400
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.0905
    Cell Significance Index: -1.3000
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: -0.0905
    Cell Significance Index: -1.4600
  • Cell Name: effector CD8-positive, alpha-beta T cell (CL0001050)
    Fold Change: -0.0912
    Cell Significance Index: -0.7700
  • Cell Name: mature T cell (CL0002419)
    Fold Change: -0.0917
    Cell Significance Index: -0.6600
  • Cell Name: effector memory CD8-positive, alpha-beta T cell (CL0000913)
    Fold Change: -0.0919
    Cell Significance Index: -0.7200
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0919
    Cell Significance Index: -1.8500
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.0927
    Cell Significance Index: -1.2500
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0931
    Cell Significance Index: -1.8400
  • Cell Name: CD8-positive, alpha-beta memory T cell (CL0000909)
    Fold Change: -0.0936
    Cell Significance Index: -0.9500
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: -0.0939
    Cell Significance Index: -0.8000
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.0947
    Cell Significance Index: -1.4400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **KIR Family Member**: KIR3DL2 belongs to the KIR family, which consists of receptors expressed on the surface of NK cells and other immune cells. These receptors play a critical role in regulating the immune response by modulating the interaction between NK cells and their ligands. 2. **Three-IG Domain Structure**: The KIR3DL2 receptor has a unique three-IG domain structure, which is distinct from other KIR family members. This structure is thought to contribute to its ability to bind to MHC class I molecules. 3. **Long Cytoplasmic Tail**: The long cytoplasmic tail of KIR3DL2 is essential for its signaling function. This tail contains immunoreceptor tyrosine-based inhibitory motifs (ITIMs), which mediate the inhibitory signaling downstream of the receptor. 4. **MHC Class I Binding**: KIR3DL2 binds to MHC class I molecules, which are essential for the proper functioning of NK cells. This interaction regulates the activity of NK cells and influences their ability to recognize and kill target cells. **Pathways and Functions** 1. **Adaptive Immune System**: KIR3DL2 plays a critical role in the adaptive immune system by regulating the activity of NK cells. These cells are key components of the innate immune system, and their dysregulation can lead to immunodeficiency or autoimmune diseases. 2. **Cellular Defense Response**: KIR3DL2 is involved in the cellular defense response, which is the body's first line of defense against pathogens. The receptor helps to regulate the interaction between NK cells and their ligands, ensuring that the immune response is properly activated and terminated. 3. **Immune System Regulation**: KIR3DL2 regulates the immune system by modulating the activity of NK cells. This receptor is involved in the immune system's ability to recognize and eliminate infected cells or tumor cells. 4. **Immunoregulatory Interactions**: KIR3DL2 is involved in immunoregulatory interactions between lymphoid and non-lymphoid cells, such as between NK cells and dendritic cells. These interactions are essential for the proper functioning of the immune system. **Clinical Significance** 1. **Immunodeficiency Diseases**: Variants of the KIR3DL2 gene have been associated with immunodeficiency diseases, such as NK cell deficiency. These diseases are characterized by impaired immune function and increased susceptibility to infections. 2. **Cancer**: KIR3DL2 has been implicated in cancer, as it is involved in the regulation of tumor cell recognition and elimination by NK cells. Alterations in the KIR3DL2 gene may contribute to the development of cancer. 3. **Autoimmune Diseases**: KIR3DL2 has been linked to autoimmune diseases, such as type 1 diabetes and rheumatoid arthritis. Variants of the KIR3DL2 gene may contribute to the development of these diseases by regulating the activity of NK cells. 4. **Transplantation**: KIR3DL2 has been used as a biomarker in transplantation medicine, as it is involved in the regulation of NK cell activity. This receptor is essential for the proper functioning of the immune system in transplant recipients. In conclusion, the KIR3DL2 gene plays a critical role in regulating the adaptive immune response by modulating the activity of NK cells. Its dysregulation can lead to immunodeficiency, autoimmune diseases, and cancer. Further research is needed to fully understand the clinical significance of KIR3DL2 and its implications for human health.

Genular Protein ID: 1081583369

Symbol: KI3L2_HUMAN

Name: CD158 antigen-like family member K

UniProtKB Accession Codes:

P43630 Q13238 Q14947 Q14948 Q92684 Q95366 Q95367 Q95368

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEMBL 1 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 9 Ensembl 20 ExpressionAtlas 1 GO 4 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 2 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 7716543

Title: Cloning of immunoglobulin-superfamily members associated with HLA-C and HLA-B recognition by human natural killer cells.

PubMed ID: 7716543

DOI: 10.1126/science.7716543

PubMed ID: 8777725

Title: Killer cell inhibitory receptors specific for HLA-C and HLA-B identified by direct binding and by functional transfer.

PubMed ID: 8777725

DOI: 10.1016/1074-7613(95)90069-1

PubMed ID: 8760804

Title: The natural killer cell receptor specific for HLA-A allotypes: a novel member of the p58/p70 family of inhibitory receptors that is characterized by three immunoglobulin-like domains and is expressed as a 140-kD disulphide-linked dimer.

PubMed ID: 8760804

DOI: 10.1084/jem.184.2.505

PubMed ID: 8662091

Title: Alternatively spliced forms of human killer inhibitory receptors.

PubMed ID: 8662091

DOI: 10.1007/bf02602590

PubMed ID: 24018270

Title: HLA-F and MHC class I open conformers are ligands for NK cell Ig-like receptors.

PubMed ID: 24018270

DOI: 10.4049/jimmunol.1300081

PubMed ID: 26928464

Title: Major histocompatibility complex class I molecules protect motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis.

PubMed ID: 26928464

DOI: 10.1038/nm.4052

PubMed ID: 28636952

Title: Human Leukocyte Antigen F Presents Peptides and Regulates Immunity through Interactions with NK Cell Receptors.

PubMed ID: 28636952

DOI: 10.1016/j.immuni.2017.06.002

PubMed ID: 9430221

Title: Human diversity in killer cell inhibitory receptor genes.

PubMed ID: 9430221

DOI: 10.1016/s1074-7613(00)80394-5

Sequence Information:

  • Length: 455
  • Mass: 50230
  • Checksum: DB4BA6BB6B3C2945
  • Sequence:
    • MSLTVVSMAC VGFFLLQGAW PLMGGQDKPF LSARPSTVVP RGGHVALQCH YRRGFNNFML 
YKEDRSHVPI FHGRIFQESF IMGPVTPAHA GTYRCRGSRP HSLTGWSAPS NPLVIMVTGN 
HRKPSLLAHP GPLLKSGETV ILQCWSDVMF EHFFLHREGI SEDPSRLVGQ IHDGVSKANF 
SIGPLMPVLA GTYRCYGSVP HSPYQLSAPS DPLDIVITGL YEKPSLSAQP GPTVQAGENV 
TLSCSSWSSY DIYHLSREGE AHERRLRAVP KVNRTFQADF PLGPATHGGT YRCFGSFRAL 
PCVWSNSSDP LLVSVTGNPS SSWPSPTEPS SKSGICRHLH VLIGTSVVIF LFILLLFFLL 
YRWCSNKKNA AVMDQEPAGD RTVNRQDSDE QDPQEVTYAQ LDHCVFIQRK ISRPSQRPKT 
PLTDTSVYTE LPNAEPRSKV VSCPRAPQSG LEGVF

Genular Protein ID: 1173352897

Symbol: Q8NHI6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8NHI6

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 1

Citations:

PubMed ID: 11859120

Title: Allelic polymorphism synergizes with variable gene content to individualize human KIR genotype.

PubMed ID: 11859120

Sequence Information:

  • Length: 432
  • Mass: 47776
  • Checksum: 94ADE5F474591D4E
  • Sequence:
    • GGQDKPFLSA RPSTVVPRGG HVALQCHYRR GFNNFMLYKE DRSHVPIFHG RIFQESFIMG 
PVTPAHAGTY RCRGSRPHSL TGWSAPSNPL VIMVTGNHRK PSLLAHPGPL LKSGETVILQ 
CWSDVMFEHF FLHREGISED PSRLVGQIHD GVSKANFSIG PLMPVLAGTY RCYGSVPHSP 
YQLSAPSDPL DIVITGLYEK PSLSAQPGPT VQAGENVTLS CSSWSSYDIY HLSREGEAHE 
RRLRAVPKVN RTFQADFPLG PATHGGTYRC FGSFRALPCV WSNSSDPLLV SVTGNPSSSW 
PSPTEPSSKS GICRHLHVLI GTSVVIFLFI LLLFFLLYRW CSNKKNAAVM DQEPAGDRTV 
NRQDSDEQDP QEVMYAQLDH CVFIQRKISR PSQRPKTPLT DTSVYTELPN AEPRSKVVSC 
PRAPQSGLEG VF

Genular Protein ID: 906370089

Symbol: Q8NHK6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8NHK6 A0A0C4ZNW6

Database IDs:

ARBA 2 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 4 GO 1 Gene3D 1 HGNC 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 PharmGKB 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMART 2 SUPFAM 1 UCSC 1

Citations:

PubMed ID: 11207248

Title: Different NK cell surface phenotypes defined by the DX9 antibody are due to KIR3DL1 gene polymorphism.

PubMed ID: 11207248

Sequence Information:

  • Length: 455
  • Mass: 50211
  • Checksum: B60046AFD478D7AF
  • Sequence:
    • MSLTVVSMAC VGFFLLQGAW PLMGGQDKPF LSARPSTVVP RGGHVALQCH YRRGFNNFML 
YKEDRSHVPI FHGRIFQESF IMGPVTPAHA GTYRCRGSRP HSLTGWSAPS NPLVIMVTGN 
HRKPSLLAHP GPLLKSGETV ILQCWSDVMF EHFFLHREGI SEDPSRLVGQ IHDGVSKANF 
SIGPLMPVLA GTYRCYGSVP HSPYQLSAPS DPLDIVITGL YEKPSLSAQP GPTVQAGENV 
TLSCSSWSSY DIYHLSREGE AHERRLRAVP KVNRTFQADF PLGPATHGGT YRCFGSFHAL 
PCVWSNSSDP LLVSVTGNPS SSWPSPTEPS SKSGICRHLH VLIGTSVVIF LFILLLFFLL 
YRWCSNKKNA AVMDQEPAGD RTVNRQDSDE QDPQEVTYAQ LDHCVFIQRK ISRPSQRPKT 
PLTDTSVYTE LPNAEPRSKV VSCPRAPQSG LEGVF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.