Details for: KRT7

Gene ID: 3855

Symbol: KRT7

Ensembl ID: ENSG00000135480

Description: keratin 7

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 68.3825
    Cell Significance Index: -28.1700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 50.5099
    Cell Significance Index: -20.5200
  • Cell Name: epithelial cell of sweat gland (CL1000448)
    Fold Change: 35.7372
    Cell Significance Index: 25.5400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 21.2727
    Cell Significance Index: -20.3100
  • Cell Name: salivary gland glandular cell (CL1001596)
    Fold Change: 17.2263
    Cell Significance Index: 95.8800
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 10.4051
    Cell Significance Index: 64.0400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 8.3280
    Cell Significance Index: 76.6900
  • Cell Name: endothelial tip cell (CL0000704)
    Fold Change: 7.5810
    Cell Significance Index: 32.6000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 7.1554
    Cell Significance Index: 333.6200
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 6.4060
    Cell Significance Index: 74.4700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 6.3767
    Cell Significance Index: 823.8300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 5.4509
    Cell Significance Index: 283.1600
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 4.8942
    Cell Significance Index: 30.4100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 4.8067
    Cell Significance Index: 358.2400
  • Cell Name: seromucus secreting cell (CL0000159)
    Fold Change: 4.6141
    Cell Significance Index: 96.2300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 4.4075
    Cell Significance Index: 794.5400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 4.0489
    Cell Significance Index: 497.8500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 3.9536
    Cell Significance Index: 107.6200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 3.6949
    Cell Significance Index: 98.6600
  • Cell Name: airway submucosal gland collecting duct epithelial cell (CL4033023)
    Fold Change: 3.3557
    Cell Significance Index: 23.5500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 3.1880
    Cell Significance Index: 149.8400
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: 2.7322
    Cell Significance Index: 10.2900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 2.6844
    Cell Significance Index: 189.8500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.5273
    Cell Significance Index: 1380.2300
  • Cell Name: peg cell (CL4033014)
    Fold Change: 2.4477
    Cell Significance Index: 56.5500
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 2.0494
    Cell Significance Index: 21.1400
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.8883
    Cell Significance Index: 11.6500
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 1.8671
    Cell Significance Index: 11.5600
  • Cell Name: mucus secreting cell of tracheobronchial tree submucosal gland (CL4033037)
    Fold Change: 1.5672
    Cell Significance Index: 10.4700
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 1.3162
    Cell Significance Index: 10.8800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.2554
    Cell Significance Index: 124.1900
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.9640
    Cell Significance Index: 17.0400
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.8823
    Cell Significance Index: 13.6500
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.8629
    Cell Significance Index: 7.6600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6281
    Cell Significance Index: 102.1600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4339
    Cell Significance Index: 47.1900
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 0.3828
    Cell Significance Index: 4.9300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.3158
    Cell Significance Index: 239.0300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3117
    Cell Significance Index: 137.7900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2523
    Cell Significance Index: 43.0800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.2454
    Cell Significance Index: 28.0200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2374
    Cell Significance Index: 16.4200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2185
    Cell Significance Index: 41.5900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1444
    Cell Significance Index: 3.6100
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 0.1413
    Cell Significance Index: 0.9800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.1248
    Cell Significance Index: 91.5200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0312
    Cell Significance Index: 0.9000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0097
    Cell Significance Index: 0.3400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.0022
    Cell Significance Index: -0.1300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0039
    Cell Significance Index: -2.8800
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.0053
    Cell Significance Index: -0.0500
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0080
    Cell Significance Index: -0.4100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0116
    Cell Significance Index: -7.2400
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0132
    Cell Significance Index: -0.5400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0153
    Cell Significance Index: -28.8900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0214
    Cell Significance Index: -0.9700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0214
    Cell Significance Index: -39.5000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0241
    Cell Significance Index: -1.9100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0257
    Cell Significance Index: -39.5000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0291
    Cell Significance Index: -39.5000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0303
    Cell Significance Index: -3.4700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0314
    Cell Significance Index: -17.7300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0370
    Cell Significance Index: -23.4700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0484
    Cell Significance Index: -0.6600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0517
    Cell Significance Index: -1.1200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0596
    Cell Significance Index: -12.5500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0629
    Cell Significance Index: -28.5400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0716
    Cell Significance Index: -2.0000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0732
    Cell Significance Index: -9.3900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0737
    Cell Significance Index: -7.5300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0772
    Cell Significance Index: -27.6800
  • Cell Name: eosinophil (CL0000771)
    Fold Change: -0.0804
    Cell Significance Index: -0.7100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1017
    Cell Significance Index: -29.2600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1054
    Cell Significance Index: -12.2800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1062
    Cell Significance Index: -14.5800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.1216
    Cell Significance Index: -24.1300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1241
    Cell Significance Index: -3.1900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.1394
    Cell Significance Index: -27.9700
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.1729
    Cell Significance Index: -1.4100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1920
    Cell Significance Index: -27.9100
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: -0.1936
    Cell Significance Index: -1.5400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2123
    Cell Significance Index: -11.0600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.2427
    Cell Significance Index: -7.1500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2451
    Cell Significance Index: -28.9000
  • Cell Name: mammary gland epithelial cell (CL0002327)
    Fold Change: -0.2541
    Cell Significance Index: -1.1700
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.2579
    Cell Significance Index: -2.9300
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.3847
    Cell Significance Index: -3.6600
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.3857
    Cell Significance Index: -3.1900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.3890
    Cell Significance Index: -14.2800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.4198
    Cell Significance Index: -28.2300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.4252
    Cell Significance Index: -12.1900
  • Cell Name: lung secretory cell (CL1000272)
    Fold Change: -0.4302
    Cell Significance Index: -3.2800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.4330
    Cell Significance Index: -27.2900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.4348
    Cell Significance Index: -12.7700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.4380
    Cell Significance Index: -28.2600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.4411
    Cell Significance Index: -33.8500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4577
    Cell Significance Index: -28.0600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.4672
    Cell Significance Index: -9.9500
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.4693
    Cell Significance Index: -4.9500
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.5092
    Cell Significance Index: -3.4500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** KRT7 is a type II keratin, which is distinct from type I keratins in terms of its expression pattern and function. Unlike type I keratins, which are primarily expressed in the epidermis, KRT7 is widely expressed in various epithelial tissues, including the lungs, skin, and gastrointestinal tract. KRT7 is also unique in its ability to form dimers with other keratin proteins, such as KRT6A, to create a stable intermediate filament network. This dimerization is essential for maintaining the structural integrity of epithelial cells and protecting them against mechanical stress. **Pathways and Functions** KRT7 is involved in several cellular pathways that regulate epithelial function and integrity. These include: 1. **Formation of the Cornified Envelope**: KRT7 is essential for the formation of the cornified envelope, a complex structure that provides mechanical strength to the epidermis. 2. **Cell Differentiation**: KRT7 plays a crucial role in regulating cell differentiation in epithelial tissues, including the development of skin and lung epithelium. 3. **Cell Adhesion**: KRT7 is involved in cell adhesion, particularly in the formation of tight junctions between epithelial cells. 4. **Mechanical Stress Response**: KRT7 helps to protect epithelial cells against mechanical stress by maintaining the structural integrity of the intermediate filament network. **Clinical Significance** Dysregulation of KRT7 has been implicated in various diseases, including: 1. **Cancer**: Alterations in KRT7 expression have been observed in several types of cancer, including breast, lung, and skin cancers. 2. **Autoimmune Disorders**: Abnormal KRT7 expression has been linked to autoimmune disorders, such as pemphigus and psoriasis. 3. **Skin Conditions**: Mutations in the KRT7 gene have been associated with skin conditions, such as epidermolysis bullosa simplex. 4. **Respiratory Diseases**: KRT7 has been implicated in the pathogenesis of respiratory diseases, such as chronic obstructive pulmonary disease (COPD). In conclusion, KRT7 is a critical component of the intermediate filament cytoskeleton, playing a vital role in maintaining epithelial integrity and function. Its dysregulation has been implicated in various diseases, highlighting the importance of KRT7 in disease pathogenesis. Further research is needed to fully elucidate the mechanisms by which KRT7 regulates epithelial function and to explore its therapeutic potential in disease treatment.

Genular Protein ID: 2192291723

Symbol: K2C7_HUMAN

Name: Keratin, type II cytoskeletal 7

UniProtKB Accession Codes:

P08729 Q92676 Q9BUD8 Q9Y3R7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CPTAC 6 CPTC 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 EMBL 17 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 10 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 2 PRIDE 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 2 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2415537

Title: Sequence and expression of a human type II mesothelial keratin.

PubMed ID: 2415537

DOI: 10.1083/jcb.101.6.2366

PubMed ID: 2459129

Title: Isolation, sequence, and differential expression of a human K7 gene in simple epithelial cells.

PubMed ID: 2459129

DOI: 10.1083/jcb.107.4.1337

PubMed ID: 10492017

Title: Sarcolectin (SCL): structure and expression of the recombinant molecule.

PubMed ID: 10492017

DOI: 10.1016/s0300-9084(99)80128-x

PubMed ID: 12359226

Title: Cloning of human, murine, and marsupial keratin 7 and a survey of K7 expression in the mouse.

PubMed ID: 12359226

DOI: 10.1016/s0006-291x(02)02288-x

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11169732

Title: Molecular interaction between human tumor marker protein p150, the largest subunit of eIF3, and intermediate filament protein K7.

PubMed ID: 11169732

DOI: 10.1002/1097-4644(20010315)80:4<483::aid-jcb1002>3.0.co;2-b

PubMed ID: 12072504

Title: Translational regulation of human papillomavirus type 16 E7 mRNA by the peptide SEQIKA, shared by rabbit alpha(1)-globin and human cytokeratin 7.

PubMed ID: 12072504

DOI: 10.1128/jvi.76.14.7040-7048.2002

PubMed ID: 11840567

Title: Cluster analysis of an extensive human breast cancer cell line protein expression map database.

PubMed ID: 11840567

DOI: 10.1002/1615-9861(200202)2:2<212::aid-prot212>3.0.co;2-h

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 21149639

Title: G protein-coupled estrogen receptor 1/G protein-coupled receptor 30 localizes in the plasma membrane and traffics intracellularly on cytokeratin intermediate filaments.

PubMed ID: 21149639

DOI: 10.1124/mol.110.069500

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 25114211

Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.

PubMed ID: 25114211

DOI: 10.1073/pnas.1413825111

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 26237509

Title: The active site of O-GlcNAc transferase imposes constraints on substrate sequence.

PubMed ID: 26237509

DOI: 10.1038/nsmb.3063

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 469
  • Mass: 51386
  • Checksum: 070CBE8F66A62497
  • Sequence:
    • MSIHFSSPVF TSRSAAFSGR GAQVRLSSAR PGGLGSSSLY GLGASRPRVA VRSAYGGPVG 
AGIREVTINQ SLLAPLRLDA DPSLQRVRQE ESEQIKTLNN KFASFIDKVR FLEQQNKLLE 
TKWTLLQEQK SAKSSRLPDI FEAQIAGLRG QLEALQVDGG RLEAELRSMQ DVVEDFKNKY 
EDEINHRTAA ENEFVVLKKD VDAAYMSKVE LEAKVDALND EINFLRTLNE TELTELQSQI 
SDTSVVLSMD NSRSLDLDGI IAEVKAQYEE MAKCSRAEAE AWYQTKFETL QAQAGKHGDD 
LRNTRNEISE MNRAIQRLQA EIDNIKNQRA KLEAAIAEAE ERGELALKDA RAKQEELEAA 
LQRGKQDMAR QLREYQELMS VKLALDIEIA TYRKLLEGEE SRLAGDGVGA VNISVMNSTG 
GSSSGGGIGL TLGGTMGSNA LSFSSSAGPG LLKAYSIRTA SASRRSARD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.