Details for: AFF3

Gene ID: 3899

Symbol: AFF3

Ensembl ID: ENSG00000144218

Description: ALF transcription elongation factor 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 427.2069
    Cell Significance Index: -66.4500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 252.1651
    Cell Significance Index: -63.9600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 135.7910
    Cell Significance Index: -64.1100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 123.9117
    Cell Significance Index: -50.3400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 54.0733
    Cell Significance Index: -66.6700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 16.3621
    Cell Significance Index: -35.8100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 9.2647
    Cell Significance Index: 158.7700
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 6.4168
    Cell Significance Index: 39.4900
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 6.2675
    Cell Significance Index: 150.3100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 6.0791
    Cell Significance Index: 173.4800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 4.8690
    Cell Significance Index: 1746.4200
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 4.7241
    Cell Significance Index: 49.2100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 4.6748
    Cell Significance Index: 314.3400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 4.0425
    Cell Significance Index: 248.4700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 3.8852
    Cell Significance Index: 171.8500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 3.5742
    Cell Significance Index: 135.3500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 3.3853
    Cell Significance Index: 1536.5000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 3.2578
    Cell Significance Index: 653.5200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.5163
    Cell Significance Index: 1740.3600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 2.4495
    Cell Significance Index: 137.4600
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 1.9258
    Cell Significance Index: 25.6900
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 1.4858
    Cell Significance Index: 18.7100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.3857
    Cell Significance Index: 274.9900
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 1.2314
    Cell Significance Index: 15.9700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.9274
    Cell Significance Index: 589.0200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.8758
    Cell Significance Index: 67.2100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.7649
    Cell Significance Index: 24.5000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.7216
    Cell Significance Index: 53.7800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.6419
    Cell Significance Index: 75.7000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.5336
    Cell Significance Index: 1004.7500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.4793
    Cell Significance Index: 30.9200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.4645
    Cell Significance Index: 88.3900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.3704
    Cell Significance Index: 8.1100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3669
    Cell Significance Index: 10.5700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3214
    Cell Significance Index: 290.1600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.2501
    Cell Significance Index: 340.0900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.2309
    Cell Significance Index: 4.7900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.1491
    Cell Significance Index: 2.9100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1121
    Cell Significance Index: 3.9400
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: 0.1101
    Cell Significance Index: 1.2000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0944
    Cell Significance Index: 9.3400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0937
    Cell Significance Index: 172.8400
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.0884
    Cell Significance Index: 1.8900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0884
    Cell Significance Index: 136.1600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 0.0710
    Cell Significance Index: 2.2600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.0692
    Cell Significance Index: 7.2100
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.0362
    Cell Significance Index: 0.5200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 0.0238
    Cell Significance Index: 0.4700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0095
    Cell Significance Index: 1.3000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0012
    Cell Significance Index: 0.1700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.0160
    Cell Significance Index: -2.6100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0460
    Cell Significance Index: -1.5100
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: -0.0471
    Cell Significance Index: -0.5200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0603
    Cell Significance Index: -3.7000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0608
    Cell Significance Index: -45.0500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0757
    Cell Significance Index: -57.3100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0769
    Cell Significance Index: -56.3900
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.0794
    Cell Significance Index: -0.9900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.1021
    Cell Significance Index: -45.1300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1150
    Cell Significance Index: -64.8600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.1172
    Cell Significance Index: -63.9900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1210
    Cell Significance Index: -75.5400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1687
    Cell Significance Index: -21.6300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.1729
    Cell Significance Index: -31.1700
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1803
    Cell Significance Index: -3.6200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1834
    Cell Significance Index: -52.7700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.2253
    Cell Significance Index: -24.5100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.3056
    Cell Significance Index: -7.6400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3158
    Cell Significance Index: -66.5300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.3225
    Cell Significance Index: -14.6200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.3435
    Cell Significance Index: -58.6600
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.3573
    Cell Significance Index: -4.5100
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: -0.3579
    Cell Significance Index: -2.7400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.3946
    Cell Significance Index: -48.5200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4003
    Cell Significance Index: -10.2900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.4324
    Cell Significance Index: -55.8600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.4324
    Cell Significance Index: -6.1900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.4379
    Cell Significance Index: -9.3000
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.4446
    Cell Significance Index: -4.2300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4744
    Cell Significance Index: -24.9100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.5141
    Cell Significance Index: -52.5200
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.5381
    Cell Significance Index: -6.9300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.5398
    Cell Significance Index: -28.1200
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.5523
    Cell Significance Index: -6.9700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.5662
    Cell Significance Index: -65.9900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.6017
    Cell Significance Index: -68.9400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.6400
    Cell Significance Index: -44.2600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.6724
    Cell Significance Index: -40.3700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.7148
    Cell Significance Index: -56.6100
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -0.8157
    Cell Significance Index: -5.9300
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.8820
    Cell Significance Index: -10.9400
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.8935
    Cell Significance Index: -7.3800
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.8948
    Cell Significance Index: -22.3200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.9094
    Cell Significance Index: -24.3300
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.9123
    Cell Significance Index: -19.7100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.9568
    Cell Significance Index: -44.9700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.9601
    Cell Significance Index: -20.8000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.9743
    Cell Significance Index: -34.1300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.0840
    Cell Significance Index: -37.6700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.0992
    Cell Significance Index: -57.1000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** AFF3 is a transcriptional regulator that belongs to the AF4/FMR2 family, which is characterized by its ability to interact with RNA polymerase II and facilitate transcriptional elongation. AFF3 is composed of three distinct domains: an RNA-binding domain, a helicase domain, and a protein-protein interaction domain. These domains enable AFF3 to regulate transcriptional elongation, interact with other transcription factors, and modulate gene expression in response to various cellular signals. **Pathways and Functions:** AFF3 is involved in several signaling pathways that regulate gene expression and transcriptional elongation, including: 1. **Super elongation complex (SEC)**: AFF3 interacts with the SEC, a complex that regulates transcriptional elongation and chromatin remodeling. 2. **DNA-binding transcription factor activity**: AFF3 binds to double-stranded DNA and regulates transcription factor activity, influencing gene expression in response to cellular signals. 3. **Regulation of DNA-templated transcription**: AFF3 modulates transcriptional elongation and chromatin remodeling, ensuring accurate transcription of DNA-templated genes. 4. **Response to tumor necrosis factor (TNF)**: AFF3 is involved in the regulation of TNF-induced gene expression, which plays a crucial role in immune response and inflammation. **Clinical Significance:** AFF3 has been implicated in various immune-mediated disorders, including: 1. **Autoimmune diseases**: AFF3 dysregulation has been linked to autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis, where aberrant gene expression and transcriptional elongation contribute to disease pathogenesis. 2. **Cancer**: AFF3 expression is often altered in cancer cells, where it can promote tumor growth and metastasis by regulating transcriptional elongation and chromatin remodeling. 3. **Neurological disorders**: AFF3 dysregulation has been implicated in neurological disorders, such as Parkinson's disease and Alzheimer's disease, where it can contribute to neuronal dysfunction and degeneration. In conclusion, AFF3 is a multifunctional protein that plays a critical role in regulating gene expression and transcriptional elongation. Its dysregulation has been implicated in various immune-mediated disorders, including autoimmune diseases, cancer, and neurological disorders. Further research is needed to elucidate the molecular mechanisms underlying AFF3's role in these diseases and to explore its potential as a therapeutic target.

Genular Protein ID: 3318184585

Symbol: AFF3_HUMAN

Name: AF4/FMR2 family member 3

UniProtKB Accession Codes:

P51826 B7ZM46 B9EGL9 D3DVI6 Q53RD6 Q53S47 Q53SI6 Q53TB9 Q59F27 Q8IWJ5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 15 Ensembl 4 ExpressionAtlas 1 GO 10 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 8 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8555498

Title: LAF-4 encodes a lymphoid nuclear protein with transactivation potential that is homologous to AF-4, the gene fused to MLL in t(4;11) leukemias.

PubMed ID: 8555498

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 28397838

Title: Mapping autosomal recessive intellectual disability: combined microarray and exome sequencing identifies 26 novel candidate genes in 192 consanguineous families.

PubMed ID: 28397838

DOI: 10.1038/mp.2017.60

PubMed ID: 31388108

Title: De novo AFF3 variant in a patient with mesomelic dysplasia with foot malformation.

PubMed ID: 31388108

DOI: 10.1038/s10038-019-0650-0

PubMed ID: 33961779

Title: Variants in the degron of AFF3 are associated with intellectual disability, mesomelic dysplasia, horseshoe kidney, and epileptic encephalopathy.

PubMed ID: 33961779

DOI: 10.1016/j.ajhg.2021.04.001

Sequence Information:

  • Length: 1226
  • Mass: 133503
  • Checksum: BD2D90358609E156
  • Sequence:
    • MDSFDLALLQ EWDLESLCVY EPDRNALRRK ERERRNQETQ QDDGTFNSSY SLFSEPYKTN 
KGDELSNRIQ NTLGNYDEMK DFLTDRSNQS HLVGVPKPGV PQTPVNKIDE HFVADSRAQN 
QPSSICSTTT STPAAVPVQQ SKRGTMGWQK AGHPPSDGQQ RATQQGSLRT LLGDGVGRQQ 
PRAKQVCNVE VGLQTQERPP AMAAKHSSSG HCVQNFPPSL ASKPSLVQQK PTAYVRPMDG 
QDQAPDESPK LKSSSETSVH CTSYRGVPAS KPEPARAKAK LSKFSIPKQG EESRSGETNS 
CVEEIIREMT WLPPLSAIQA PGKVEPTKFP FPNKDSQLVS SGHNNPKKGD AEPESPDNGT 
SNTSMLEDDL KLSSDEEENE QQAAQRTALR ALSDSAVVQQ PNCRTSVPSS KGSSSSSSSG 
SSSSSSDSES SSGSDSETES SSSESEGSKP PHFSSPEAEP ASSNKWQLDK WLNKVNPHKP 
PILIQNESHG SESNQYYNPV KEDVQDCGKV PDVCQPSLRE KEIKSTCKEE QRPRTANKAP 
GSKGVKQKSP PAAVAVAVSA AAPPPAVPCA PAENAPAPAR RSAGKKPTRR TERTSAGDGA 
NCHRPEEPAA ADALGTSVVV PPEPTKTRPC GNNRASHRKE LRSSVTCEKR RTRGLSRIVP 
KSKEFIETES SSSSSSSDSD LESEQEEYPL SKAQTVAASA SSGNDQRLKE AAANGGSGPR 
APVGSINART TSDIAKELEE QFYTLVPFGR NELLSPLKDS DEIRSLWVKI DLTLLSRIPE 
HLPQEPGVLS APATKDSESA PPSHTSDTPA EKALPKSKRK RKCDNEDDYR EIKKSQGEKD 
SSSRLATSTS NTLSANHCNM NINSVAIPIN KNEKMLRSPI SPLSDASKHK YTSEDLTSSS 
RPNGNSLFTS ASSSKKPKAD SQLQPHGGDL TKAAHNNSEN IPLHKSRPQT KPWSPGSNGH 
RDCKRQKLVF DDMPRSADYF MQEAKRMKHK ADAMVEKFGK ALNYAEAALS FIECGNAMEQ 
GPMESKSPYT MYSETVELIR YAMRLKTHSG PNATPEDKQL AALCYRCLAL LYWRMFRLKR 
DHAVKYSKAL IDYFKNSSKA AQAPSPWGAS GKSTGTPSPM SPNPSPASSV GSQGSLSNAS 
ALSPSTIVSI PQRIHQMAAN HVSITNSILH SYDYWEMADN LAKENREFFN DLDLLMGPVT 
LHSSMEHLVQ YSQQGLHWLR NSAHLS

Genular Protein ID: 3301587497

Symbol: Q8NAP7_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8NAP7

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 1 InterPro 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 781
  • Mass: 84197
  • Checksum: 4D9EA69FB89D0C01
  • Sequence:
    • MDSFDLALLQ EWDLESLWGE DILNQRNDSL VVEFQSSASR CRSVYEPDRN ALRRKERERR 
NQETQQDDGT FNSSYSLFSE PYKTNKGDEL SNRIQNTLGN YDEMKDFLTD RSNQSHLVGV 
PKPGVPQTPV NKIDEHFVAD SRAQNQPSSI CSTTTSTPAA VPVQQSKRGT MGWQKAGHPP 
SDGQQRATQQ GSLRTLLGDG VGRQQPRAKQ VCNVEVGLQT QERPPAMAAK HSSSGHCVQN 
FPPSLASKPS LVQQKPTAYV RPMDGQDQAP DESPKLKSSS ETSVHCTSYR GVPASKPEPA 
RAKAKLSKFS IPKQGEESRS GETNSCVEEI IREMTWLPPL SAIQAPGKVE PTKFPFPNKD 
SQLVSSGHNN PKKGDAEPES PDNGTSNTSM LEDDLKLSSD EEENEQQAAQ RTALRALSDS 
AVVQQPNCRT SVPSSKGSSS SSSSGSSSSS SDSESSSGSD SETESSSSES EGSKPPHFSS 
PEAEPASSNK WQLDKWLNKV NPHKPPILIQ NESHGSESNQ YYNPVKEDVQ DCGKVPDVCQ 
PSLREKEIKS TCKEEQRPRT ANKAPGSKGV KQKSPPAAVA VAVSAAAPPP AVPCAPAENA 
PAPARRSAGK KPTRRTERTS AGDGANCHRP EEPAAADALG TSVVVPPEPT KTRPCGNNRA 
SHRKELRSSV TCEKRRTRGL SRIVPKSKEF IETESSSSSS SSDSDLESEQ EEYPLSKAQT 
VAASASSGND QRLKEAAANG GSGPRAPVGS INARTTSDIA KELEEQFYTL VPLAGTNFSP 
L

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.