Details for: PRICKLE3

Gene ID: 4007

Symbol: PRICKLE3

Ensembl ID: ENSG00000012211

Description: prickle planar cell polarity protein 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 35.4238
    Cell Significance Index: -5.5100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 21.0138
    Cell Significance Index: -5.3300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 11.7413
    Cell Significance Index: -4.7700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 4.6149
    Cell Significance Index: -5.6900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 2.0568
    Cell Significance Index: -5.5100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.5811
    Cell Significance Index: 300.8900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.0392
    Cell Significance Index: 71.8700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.0349
    Cell Significance Index: 14.1200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6490
    Cell Significance Index: 38.9600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5976
    Cell Significance Index: 59.1200
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.5795
    Cell Significance Index: 9.5500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5660
    Cell Significance Index: 29.4000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4766
    Cell Significance Index: 51.8500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4610
    Cell Significance Index: 416.2100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3486
    Cell Significance Index: 42.8600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3208
    Cell Significance Index: 52.1800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.2853
    Cell Significance Index: 7.7700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.2489
    Cell Significance Index: 29.0100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2450
    Cell Significance Index: 44.1600
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.2319
    Cell Significance Index: 3.2600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2219
    Cell Significance Index: 10.0600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2100
    Cell Significance Index: 6.0500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1990
    Cell Significance Index: 5.5600
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 0.1633
    Cell Significance Index: 2.4800
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.1621
    Cell Significance Index: 2.6000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1569
    Cell Significance Index: 3.4000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.0817
    Cell Significance Index: 2.4000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.0809
    Cell Significance Index: 0.7500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0797
    Cell Significance Index: 5.6400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0664
    Cell Significance Index: 29.3500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0579
    Cell Significance Index: 11.4900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0533
    Cell Significance Index: 4.0900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0453
    Cell Significance Index: 24.7600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0440
    Cell Significance Index: 1.1000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0413
    Cell Significance Index: 1.4500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0317
    Cell Significance Index: 3.7400
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.0258
    Cell Significance Index: 0.3700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0247
    Cell Significance Index: 1.1500
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0245
    Cell Significance Index: 1.2400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0242
    Cell Significance Index: 1.2600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0230
    Cell Significance Index: 0.4900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0209
    Cell Significance Index: 2.6800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0159
    Cell Significance Index: 2.1800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0106
    Cell Significance Index: 0.3400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0106
    Cell Significance Index: 7.3500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0082
    Cell Significance Index: 12.5800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0038
    Cell Significance Index: 7.2300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0037
    Cell Significance Index: 6.9000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0026
    Cell Significance Index: 1.1600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0012
    Cell Significance Index: 1.6800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0003
    Cell Significance Index: -0.0300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0004
    Cell Significance Index: -0.2500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0013
    Cell Significance Index: -0.2300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0052
    Cell Significance Index: -0.1400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0053
    Cell Significance Index: -0.7700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0058
    Cell Significance Index: -4.3800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0066
    Cell Significance Index: -4.8700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0074
    Cell Significance Index: -5.5100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0084
    Cell Significance Index: -4.7300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0088
    Cell Significance Index: -0.9000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0104
    Cell Significance Index: -6.4900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0140
    Cell Significance Index: -2.8100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0141
    Cell Significance Index: -5.0400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0150
    Cell Significance Index: -1.1200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0158
    Cell Significance Index: -2.0400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0204
    Cell Significance Index: -0.9600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0204
    Cell Significance Index: -5.8800
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.0225
    Cell Significance Index: -0.5200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0259
    Cell Significance Index: -1.6700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0293
    Cell Significance Index: -6.1700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0363
    Cell Significance Index: -1.0400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0425
    Cell Significance Index: -2.6800
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0443
    Cell Significance Index: -0.6300
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0447
    Cell Significance Index: -0.6700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0510
    Cell Significance Index: -5.3100
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0511
    Cell Significance Index: -0.5800
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.0542
    Cell Significance Index: -0.8600
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0619
    Cell Significance Index: -1.5900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0624
    Cell Significance Index: -4.9400
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.0627
    Cell Significance Index: -0.8700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0628
    Cell Significance Index: -3.8500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0638
    Cell Significance Index: -1.1800
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0650
    Cell Significance Index: -1.6200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0823
    Cell Significance Index: -4.6200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0849
    Cell Significance Index: -5.7100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0871
    Cell Significance Index: -5.3600
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: -0.0884
    Cell Significance Index: -0.7600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0893
    Cell Significance Index: -2.3900
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0898
    Cell Significance Index: -0.9300
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0903
    Cell Significance Index: -2.8600
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.0910
    Cell Significance Index: -0.5500
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: -0.1024
    Cell Significance Index: -0.6800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1089
    Cell Significance Index: -5.7200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1099
    Cell Significance Index: -4.0400
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.1141
    Cell Significance Index: -2.8500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1221
    Cell Significance Index: -3.2100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.1277
    Cell Significance Index: -2.7300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1277
    Cell Significance Index: -5.6500
  • Cell Name: myometrial cell (CL0002366)
    Fold Change: -0.1311
    Cell Significance Index: -1.5100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1339
    Cell Significance Index: -4.6900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** PRICKLE3 is a member of the prickle family of proteins, which are known to regulate cell polarity through interactions with other key components of the planar cell polarity (PCP) pathway. The PRICKLE3 protein contains a LIM domain, which is essential for its function in regulating cell polarity. The gene is significantly expressed in various cell types, including retina horizontal cells, amacrine cells, cerebral cortex GABAergic interneurons, and cardiac endothelial cells. PRICKLE3 has been shown to interact with other proteins, including the LIM domain-only protein 6 (PRIC3_HUMAN), which is also involved in cell polarity regulation. **Pathways and Functions** The PRICKLE3 protein is involved in the regulation of cell polarity through interactions with the PCP pathway, which is a complex signaling cascade that regulates cell-cell adhesion, migration, and differentiation. The PCP pathway involves the coordinated action of several key proteins, including PAR (partitioning defective) proteins, which are required for the establishment and maintenance of cellular polarity. PRICKLE3 has been shown to interact with PAR proteins, such as PAR-3 and PAR-6, to regulate cell polarity. Additionally, PRICKLE3 has been implicated in the regulation of cell migration and differentiation, which are critical processes in development and tissue homeostasis. **Clinical Significance** Dysregulation of PRICKLE3 has been implicated in various diseases, including cancer and neurological disorders. For example, mutations in the PRICKLE3 gene have been associated with cancer, including colorectal cancer and breast cancer. Additionally, PRICKLE3 has been implicated in neurological disorders, such as Alzheimer's disease and Parkinson's disease. The disruption of cellular polarity due to PRICKLE3 dysregulation can lead to the development of these diseases, highlighting the importance of PRICKLE3 in maintaining tissue homeostasis. In conclusion, PRICKLE3 is a critical component of the cell polarity machinery, and its dysregulation can have significant implications for human health. Further studies are needed to fully understand the mechanisms by which PRICKLE3 regulates cell polarity and its role in disease. However, the current evidence suggests that PRICKLE3 is a key player in maintaining tissue homeostasis, and its dysregulation can contribute to the development of various diseases.

Genular Protein ID: 506669215

Symbol: PRIC3_HUMAN

Name: LIM domain only protein 6

UniProtKB Accession Codes:

O43900 B7Z8F2 O76007 Q53XR5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 4 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 1 ExpressionAtlas 1 GO 4 Gene3D 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9344658

Title: Sequence-based exon prediction around the synaptophysin locus reveals a gene-rich area containing novel genes in human proximal Xp.

PubMed ID: 9344658

DOI: 10.1006/geno.1997.4941

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 32516135

Title: PRICKLE3 linked to ATPase biogenesis manifested Leber's hereditary optic neuropathy.

PubMed ID: 32516135

DOI: 10.1172/jci134965

Sequence Information:

  • Length: 615
  • Mass: 68609
  • Checksum: CD024365C072B052
  • Sequence:
    • MFARGSRRRR SGRAPPEAED PDRGQPCNSC REQCPGFLLH GWRKICQHCK CPREEHAVHA 
VPVDLERIMC RLISDFQRHS ISDDDSGCAS EEYAWVPPGL KPEQVYQFFS CLPEDKVPYV 
NSPGEKYRIK QLLHQLPPHD SEAQYCTALE EEEKKELRAF SQQRKRENLG RGIVRIFPVT 
ITGAICEECG KQIGGGDIAV FASRAGLGAC WHPQCFVCTT CQELLVDLIY FYHVGKVYCG 
RHHAECLRPR CQACDEIIFS PECTEAEGRH WHMDHFCCFE CEASLGGQRY VMRQSRPHCC 
ACYEARHAEY CDGCGEHIGL DQGQMAYEGQ HWHASDRCFC CSRCGRALLG RPFLPRRGLI 
FCSRACSLGS EPTAPGPSRR SWSAGPVTAP LAASTASFSA VKGASETTTK GTSTELAPAT 
GPEEPSRFLR GAPHRHSMPE LGLRSVPEPP PESPGQPNLR PDDSAFGRQS TPRVSFRDPL 
VSEGGPRRTL SAPPAQRRRP RSPPPRAPSR RRHHHHNHHH HHNRHPSRRR HYQCDAGSGS 
DSESCSSSPS SSSSESSEDD GFFLGERIPL PPHLCRPMPA QDTAMETFNS PSLSLPRDSR 
AGMPRQARDK NCIVA

Genular Protein ID: 1277312547

Symbol: B7Z8D2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z8D2

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 4 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 1 InterPro 7 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 2 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 547
  • Mass: 60758
  • Checksum: DE5D61350E018595
  • Sequence:
    • MCRLISDFQR HSISDDDSGC ASEEYAWVPP GLKPEQVYQF FSCLPEDKVP YVNSPGEKYR 
IKQLLHQLPP HDSEAQYCTA LEEEEKKELR AFSQQRKREN LGRGIVRIFP VTITGAICEE 
CGKQIGGGDI AVFASRAGLG ACWHPQCFVC TTCQELLVDL IYFYHVGKVY CGRHHAECLR 
PRCQACDEII FSPECTEAEG RHWHMDHFCC FECEASLGGQ RYVMRQSRPH CCACYEARHA 
EYCDGCGEHI GLDQGQMAYE GQHWHASDRC FCCSRCGRAL LGRPFLPRRG LIFCSRACSL 
GSEPTAPGPS RRSWSAGPVT APLAASTASF SAVKGASETT TKGTSTELAP ATGPEEPSRF 
LRGAPHRHSM PELGLRSVPE PPPESPGQPN LRPDDSAFGR QSTPRVSFRD PLVSEGGPRR 
TLSAPPAQRR RPRSPPPRAP SRRRHHHHNH HHHHNRHPSR RRHYQCDAGS GSDSESCSSS 
PSSSSSESSE DDGLFLGERI PLPPHLCRPM PAQDTAMETF NSPSLSLPRD SRAGMPRQAR 
DKNCIVA

Genular Protein ID: 1112023329

Symbol: H0Y413_HUMAN

Name: N/A

UniProtKB Accession Codes:

H0Y413

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 4 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 HGNC 1 IntAct 1 InterPro 7 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 547
  • Mass: 60792
  • Checksum: 245761350E0C3EF8
  • Sequence:
    • MCRLISDFQR HSISDDDSGC ASEEYAWVPP GLKPEQVYQF FSCLPEDKVP YVNSPGEKYR 
IKQLLHQLPP HDSEAQYCTA LEEEEKKELR AFSQQRKREN LGRGIVRIFP VTITGAICEE 
CGKQIGGGDI AVFASRAGLG ACWHPQCFVC TTCQELLVDL IYFYHVGKVY CGRHHAECLR 
PRCQACDEII FSPECTEAEG RHWHMDHFCC FECEASLGGQ RYVMRQSRPH CCACYEARHA 
EYCDGCGEHI GLDQGQMAYE GQHWHASDRC FCCSRCGRAL LGRPFLPRRG LIFCSRACSL 
GSEPTAPGPS RRSWSAGPVT APLAASTASF SAVKGASETT TKGTSTELAP ATGPEEPSRF 
LRGAPHRHSM PELGLRSVPE PPPESPGQPN LRPDDSAFGR QSTPRVSFRD PLVSEGGPRR 
TLSAPPAQRR RPRSPPPRAP SRRRHHHHNH HHHHNRHPSR RRHYQCDAGS GSDSESCSSS 
PSSSSSESSE DDGFFLGERI PLPPHLCRPM PAQDTAMETF NSPSLSLPRD SRAGMPRQAR 
DKNCIVA

Genular Protein ID: 3594752459

Symbol: B7Z5U0_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z5U0

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 2 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 439
  • Mass: 49105
  • Checksum: E97B9F793EF75333
  • Sequence:
    • MFARGSRRRR SGRAPPEAED PDRGQPCNSC REQCPGFLLH GWRKICQHCK CPREEHAVHA 
VPVDLERIMC RLISDFQRHS ISDDDSGCAS EEYAWVPPGL KPEQVTRGQP STLAVQWVHT 
NAHTHTHTQA QYCTALEEEE KKELRAFSQQ RKRENLGRGI VRIFPVTITG AICEECGKQI 
GGGDIAVFAS RAGLGACWHP QCFVCTTCQE LLVDLIYFYH VGKVYCGRHH AECLRPRCQA 
CDEIIFSPEC TPGPAPQATQ PSRFLRGAPH RHSMPELGLR SVPEPPPESP GQPNLRPDDS 
AFGRQSTPRV SFRDPLVSEG GPRRTLSAPP AQRRRRHHHH NHHHHHNRHP SRRRHYQCDA 
GSGSDSESCS SSPSSSSSES SEDDGFFLGE RIPLPPHLCR PMPAQDTAME TFNSPSLSLP 
RDSRAGMPRQ ARDKNCIVA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.