Details for: MAOA

Gene ID: 4128

Symbol: MAOA

Ensembl ID: ENSG00000189221

Description: monoamine oxidase A

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 174.4830
    Cell Significance Index: -27.1400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 107.2766
    Cell Significance Index: -27.2100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 60.5036
    Cell Significance Index: -24.5800
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 43.9628
    Cell Significance Index: -29.5000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 25.7556
    Cell Significance Index: -24.5900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 21.9635
    Cell Significance Index: -27.0800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 11.6094
    Cell Significance Index: -31.1000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 7.0456
    Cell Significance Index: -15.4200
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.8980
    Cell Significance Index: -27.2200
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 6.7660
    Cell Significance Index: 60.0600
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 5.7224
    Cell Significance Index: 60.8000
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 3.2663
    Cell Significance Index: 41.1300
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 3.0227
    Cell Significance Index: 48.5000
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 2.9198
    Cell Significance Index: 29.4600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.8174
    Cell Significance Index: 38.4400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 2.7397
    Cell Significance Index: 142.3200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.1650
    Cell Significance Index: 58.9300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.1243
    Cell Significance Index: 61.2100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 2.1079
    Cell Significance Index: 380.0000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.9425
    Cell Significance Index: 238.8500
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.6670
    Cell Significance Index: 28.0800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.5333
    Cell Significance Index: 42.8500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.4165
    Cell Significance Index: 1278.9900
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.4009
    Cell Significance Index: 12.9000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.2324
    Cell Significance Index: 200.4400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 1.1108
    Cell Significance Index: 78.5600
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.0552
    Cell Significance Index: 6.5100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.9218
    Cell Significance Index: 55.3400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.8931
    Cell Significance Index: 177.2500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.8906
    Cell Significance Index: 46.3900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.8002
    Cell Significance Index: 37.3100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.7690
    Cell Significance Index: 59.0200
  • Cell Name: seromucus secreting cell (CL0000159)
    Fold Change: 0.6722
    Cell Significance Index: 14.0200
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.6293
    Cell Significance Index: 3.9100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.5030
    Cell Significance Index: 16.1100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4326
    Cell Significance Index: 59.4100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3425
    Cell Significance Index: 151.4100
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.3063
    Cell Significance Index: 4.5900
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.2705
    Cell Significance Index: 6.2500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2674
    Cell Significance Index: 50.8900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2580
    Cell Significance Index: 16.2600
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.2425
    Cell Significance Index: 2.5100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.2348
    Cell Significance Index: 5.0000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1909
    Cell Significance Index: 104.2600
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.1328
    Cell Significance Index: 0.9000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1184
    Cell Significance Index: 11.7100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1169
    Cell Significance Index: 23.4500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1156
    Cell Significance Index: 73.4200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0939
    Cell Significance Index: 3.3000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0851
    Cell Significance Index: 64.4500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0672
    Cell Significance Index: 24.0900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0363
    Cell Significance Index: 26.6100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0358
    Cell Significance Index: 24.7400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0322
    Cell Significance Index: 1.4600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0174
    Cell Significance Index: 1.2100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0160
    Cell Significance Index: 7.2600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0036
    Cell Significance Index: 0.2700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0019
    Cell Significance Index: 0.0500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0014
    Cell Significance Index: -2.5500
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: -0.0030
    Cell Significance Index: -0.0400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0069
    Cell Significance Index: -0.8800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0113
    Cell Significance Index: -1.3000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0116
    Cell Significance Index: -15.7800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0125
    Cell Significance Index: -23.0000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0162
    Cell Significance Index: -24.8700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0342
    Cell Significance Index: -25.3100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0362
    Cell Significance Index: -6.1900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0468
    Cell Significance Index: -26.4100
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0513
    Cell Significance Index: -32.0500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0571
    Cell Significance Index: -5.8300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0673
    Cell Significance Index: -19.3600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0676
    Cell Significance Index: -1.6900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0698
    Cell Significance Index: -8.1300
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0725
    Cell Significance Index: -1.0700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0859
    Cell Significance Index: -1.8600
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.1304
    Cell Significance Index: -1.1000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1422
    Cell Significance Index: -29.9500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1474
    Cell Significance Index: -21.4200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1480
    Cell Significance Index: -11.7200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1973
    Cell Significance Index: -25.4900
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.2338
    Cell Significance Index: -3.3500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.2347
    Cell Significance Index: -2.4300
  • Cell Name: myometrial cell (CL0002366)
    Fold Change: -0.2468
    Cell Significance Index: -2.8400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2494
    Cell Significance Index: -25.9700
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.2821
    Cell Significance Index: -1.7500
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.3014
    Cell Significance Index: -5.0700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3081
    Cell Significance Index: -18.8900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3303
    Cell Significance Index: -20.3000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3361
    Cell Significance Index: -22.6000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.3465
    Cell Significance Index: -4.1300
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.4009
    Cell Significance Index: -6.3600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.4070
    Cell Significance Index: -22.8400
  • Cell Name: colonocyte (CL1000347)
    Fold Change: -0.4110
    Cell Significance Index: -2.5400
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.4509
    Cell Significance Index: -2.9400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.4770
    Cell Significance Index: -9.3100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.4773
    Cell Significance Index: -30.7900
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4782
    Cell Significance Index: -7.0600
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: -0.4952
    Cell Significance Index: -1.8700
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.4966
    Cell Significance Index: -18.2300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.5118
    Cell Significance Index: -25.8600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** MAOA exhibits several distinct characteristics, including: 1. **Flavin adenine dinucleotide (FAD) dependence**: MAOA requires FAD as a cofactor to catalyze the oxidative deamination of neurotransmitters. 2. **Broad substrate specificity**: MAOA can degrade various neurotransmitters, including dopamine, serotonin, and norepinephrine, as well as biogenic amines such as histamine and tyramine. 3. **Cytosolic and mitochondrial localization**: MAOA is found in both the cytosol and mitochondria of cells, suggesting a role in both the cytosolic and mitochondrial compartments. 4. **Cellular distribution**: MAOA is expressed in various cell types, including pulmonary interstitial fibroblasts, mesenchymal stem cells, and neural progenitor cells. 5. **Regulatory mechanisms**: MAOA is subject to various regulatory mechanisms, including positive regulation by interleukin-4 and interleukin-13 signaling pathways. **Pathways and Functions** MAOA participates in several key pathways, including: 1. **Neurotransmitter clearance**: MAOA plays a critical role in regulating neurotransmitter levels by degrading dopamine, serotonin, and norepinephrine. 2. **Cytokine signaling**: MAOA is involved in the regulation of cytokine signaling, including the positive regulation of interleukin-4 and interleukin-13 signaling pathways. 3. **Biogenic amine metabolism**: MAOA is responsible for the oxidative deamination of biogenic amines, leading to their degradation and clearance. 4. **Mitochondrial function**: MAOA is localized to the mitochondrial outer membrane, suggesting a role in mitochondrial function and energy metabolism. **Clinical Significance** Dysregulation of MAOA has been implicated in various neurological and psychiatric disorders, including: 1. **Aggression and violence**: MAOA has been associated with aggression and violence, particularly in individuals with a history of trauma or abuse. 2. **Mood disorders**: MAOA has been implicated in the regulation of mood, and alterations in MAOA expression have been observed in individuals with depression and bipolar disorder. 3. **Neurodegenerative diseases**: MAOA has been implicated in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. 4. **Cancer**: MAOA has been identified as a potential biomarker for cancer diagnosis and prognosis, particularly in gastrointestinal cancers. In conclusion, MAOA is a critical enzyme involved in the regulation of neurotransmitter levels and cytokine signaling, and its dysregulation has been implicated in various neurological and psychiatric disorders. Further research is needed to fully understand the role of MAOA in human health and disease.

Genular Protein ID: 3421785301

Symbol: AOFA_HUMAN

Name: Monoamine oxidase type A

UniProtKB Accession Codes:

P21397 B4DF46 Q16426

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChEBI 61 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 67 DrugCentral 1 EC 2 EMBL 40 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 10 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 1 PRINTS 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 8 RefSeq 2 Rhea 11 SABIO-RK 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3418353

Title: Structural features of human monoamine oxidase A elucidated from cDNA and peptide sequences.

PubMed ID: 3418353

DOI: 10.1111/j.1471-4159.1988.tb03105.x

PubMed ID: 3387449

Title: cDNA cloning of human liver monoamine oxidase A and B: molecular basis of differences in enzymatic properties.

PubMed ID: 3387449

DOI: 10.1073/pnas.85.13.4934

PubMed ID: 1886775

Title: Structure of the human gene for monoamine oxidase type A.

PubMed ID: 1886775

DOI: 10.1093/nar/19.16.4537

PubMed ID: 2023912

Title: Human monoamine oxidase A and B genes exhibit identical exon-intron organization.

PubMed ID: 2023912

DOI: 10.1073/pnas.88.9.3637

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15772651

Title: The DNA sequence of the human X chromosome.

PubMed ID: 15772651

DOI: 10.1038/nature03440

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1432104

Title: Promoter organization and activity of human monoamine oxidase (MAO) A and B genes.

PubMed ID: 1432104

DOI: 10.1523/jneurosci.12-11-04437.1992

PubMed ID: 8584674

Title: The promoter of the human monoamine oxidase A gene.

PubMed ID: 8584674

DOI: 10.1016/s0079-6123(08)61202-9

PubMed ID: 7519662

Title: A new look at the promoter of the human monoamine oxidase A gene: mapping transcription initiation sites and capacity to drive luciferase expression.

PubMed ID: 7519662

DOI: 10.1046/j.1471-4159.1994.63030843.x

PubMed ID: 3178846

Title: Partial amino acid sequence analysis of human placenta monoamine oxidase A and bovine liver monoamine oxidase B.

PubMed ID: 3178846

DOI: 10.1016/s0006-291x(88)80861-1

PubMed ID: 11812236

Title: High-level expression of human liver monoamine oxidase A in Pichia pastoris: comparison with the enzyme expressed in Saccharomyces cerevisiae.

PubMed ID: 11812236

DOI: 10.1006/prep.2001.1546

PubMed ID: 20493079

Title: The oxidation of adrenaline and noradrenaline by the two forms of monoamine oxidase from human and rat brain.

PubMed ID: 20493079

DOI: 10.1016/0197-0186(86)90182-8

PubMed ID: 2764901

Title: Monoamine oxidase A from human placenta and monoamine oxidase B from bovine liver both have one FAD per subunit.

PubMed ID: 2764901

DOI: 10.1042/bj2600725

PubMed ID: 8316221

Title: Site-directed mutagenesis of monoamine oxidase A and B: role of cysteines.

PubMed ID: 8316221

PubMed ID: 8211186

Title: Abnormal behavior associated with a point mutation in the structural gene for monoamine oxidase A.

PubMed ID: 8211186

DOI: 10.1126/science.8211186

PubMed ID: 9799080

Title: A functional polymorphism in the monoamine oxidase A gene promoter.

PubMed ID: 9799080

DOI: 10.1007/s004390050816

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 16129825

Title: Three-dimensional structure of human monoamine oxidase A (MAO A): relation to the structures of rat MAO A and human MAO B.

PubMed ID: 16129825

DOI: 10.1073/pnas.0505975102

PubMed ID: 18391214

Title: Structure of human monoamine oxidase A at 2.2-A resolution: the control of opening the entry for substrates/inhibitors.

PubMed ID: 18391214

DOI: 10.1073/pnas.0710626105

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 21179162

Title: A population-specific HTR2B stop codon predisposes to severe impulsivity.

PubMed ID: 21179162

DOI: 10.1038/nature09629

PubMed ID: 24169519

Title: 20 ans apres: a second mutation in MAOA identified by targeted high-throughput sequencing in a family with altered behavior and cognition.

PubMed ID: 24169519

DOI: 10.1038/ejhg.2013.243

Sequence Information:

  • Length: 527
  • Mass: 59682
  • Checksum: 4270E346928AE832
  • Sequence:
    • MENQEKASIA GHMFDVVVIG GGISGLSAAK LLTEYGVSVL VLEARDRVGG RTYTIRNEHV 
DYVDVGGAYV GPTQNRILRL SKELGIETYK VNVSERLVQY VKGKTYPFRG AFPPVWNPIA 
YLDYNNLWRT IDNMGKEIPT DAPWEAQHAD KWDKMTMKEL IDKICWTKTA RRFAYLFVNI 
NVTSEPHEVS ALWFLWYVKQ CGGTTRIFSV TNGGQERKFV GGSGQVSERI MDLLGDQVKL 
NHPVTHVDQS SDNIIIETLN HEHYECKYVI NAIPPTLTAK IHFRPELPAE RNQLIQRLPM 
GAVIKCMMYY KEAFWKKKDY CGCMIIEDED APISITLDDT KPDGSLPAIM GFILARKADR 
LAKLHKEIRK KKICELYAKV LGSQEALHPV HYEEKNWCEE QYSGGCYTAY FPPGIMTQYG 
RVIRQPVGRI FFAGTETATK WSGYMEGAVE AGERAAREVL NGLGKVTEKD IWVQEPESKD 
VPAVEITHTF WERNLPSVSG LLKIIGFSTS VTALGFVLYK YKLLPRS

Genular Protein ID: 4106414237

Symbol: Q49A63_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q49A63

Database IDs:

ARBA 22 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 61 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 2 EMBL 2 GO 5 Gene3D 4 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 1 Pfam 2 RefSeq 2 Rhea 11 RuleBase 1 SMR 1 SUPFAM 2

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 527
  • Mass: 59741
  • Checksum: 36E11C6730D961B7
  • Sequence:
    • MENQEKASIA GHMFDVVVIG GGISGLSAAK LLTEYDVSVL VLEARDRVGG RTYTIRNEHV 
DYVDVGGAYV GPTQNRILRL SKELGIETYK VNVSERLVQY VKGKTYPFRG AFPPVWNPIA 
YLDYNNLWRT IDNMGKEIPT DAPWEAQHAD KWDEMTMKEL IDKICWTKTA RRFAYLFVNI 
NVTSEPHEVS ALWFLWYVKQ CGGTTRIFSV TNGGQERKFV GGSGQVSERI MDLLGDQVKL 
NHPVTHVDQS SDNIIIETLN HEHYECKYVI NAIPPTLTAK IHFRPELPAE RNQLIQRLPM 
GAVIKCMMYY KEAFWKKKDY CGCMIIEDED APISITLDDT KPDGSLPAIM GFILARKADR 
LAKLHKEIRK KKICELYAKV LGSQEALHPV HYEEKNWCEE QYSGGCYTAY FPPGIMTQYG 
RVIRQPVGRI FFAGTETATK WSGYMEGAVE AGERAAREVL NGLGKVTEKD IWVQEPESKD 
VPAVEITHTF WERNLPSVSG LLKIIGFSTS VTALGFVLYK YKLLPRS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.