Details for: MMP3

Gene ID: 4314

Symbol: MMP3

Ensembl ID: ENSG00000149968

Description: matrix metallopeptidase 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 6.6190
    Cell Significance Index: 113.1500
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 3.9176
    Cell Significance Index: 26.5400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 3.5558
    Cell Significance Index: 101.9300
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 2.4514
    Cell Significance Index: 31.7200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 2.2057
    Cell Significance Index: 33.0500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 2.0534
    Cell Significance Index: 125.8900
  • Cell Name: endothelial tip cell (CL0000704)
    Fold Change: 1.9162
    Cell Significance Index: 8.2400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.4823
    Cell Significance Index: 47.4800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 1.0597
    Cell Significance Index: -2.3200
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.0342
    Cell Significance Index: 9.1800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.7163
    Cell Significance Index: 136.3100
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: 0.4760
    Cell Significance Index: 4.0900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4607
    Cell Significance Index: 45.5700
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.3936
    Cell Significance Index: 6.0900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3398
    Cell Significance Index: 306.8500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2770
    Cell Significance Index: 16.6300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.2646
    Cell Significance Index: 28.7800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2224
    Cell Significance Index: 36.1700
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 0.2146
    Cell Significance Index: 2.7100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1190
    Cell Significance Index: 8.2300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0436
    Cell Significance Index: 5.5900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0214
    Cell Significance Index: 39.4700
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.0196
    Cell Significance Index: 0.3000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0195
    Cell Significance Index: 2.4000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0191
    Cell Significance Index: 0.5500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0048
    Cell Significance Index: 0.1200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0039
    Cell Significance Index: 5.9500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0023
    Cell Significance Index: 0.4200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0004
    Cell Significance Index: -0.2700
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.0015
    Cell Significance Index: -0.0200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0020
    Cell Significance Index: -1.5000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0029
    Cell Significance Index: -1.6500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0036
    Cell Significance Index: -4.8500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0038
    Cell Significance Index: -7.2300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0039
    Cell Significance Index: -2.1400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0054
    Cell Significance Index: -0.1900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0059
    Cell Significance Index: -0.3000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0062
    Cell Significance Index: -1.0600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0087
    Cell Significance Index: -1.8400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0090
    Cell Significance Index: -5.6900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0095
    Cell Significance Index: -0.4500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0097
    Cell Significance Index: -7.3100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0119
    Cell Significance Index: -5.3900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0120
    Cell Significance Index: -0.2600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0203
    Cell Significance Index: -0.9200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0206
    Cell Significance Index: -2.3600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0247
    Cell Significance Index: -2.8800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0308
    Cell Significance Index: -3.5200
  • Cell Name: precursor cell (CL0011115)
    Fold Change: -0.0316
    Cell Significance Index: -0.2400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0334
    Cell Significance Index: -6.6900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0385
    Cell Significance Index: -5.6000
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0387
    Cell Significance Index: -1.5900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0406
    Cell Significance Index: -0.8500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0419
    Cell Significance Index: -0.8700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0423
    Cell Significance Index: -0.9000
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.0435
    Cell Significance Index: -0.6900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0445
    Cell Significance Index: -8.8300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0457
    Cell Significance Index: -6.2800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0458
    Cell Significance Index: -5.9200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0462
    Cell Significance Index: -4.7200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0520
    Cell Significance Index: -0.7100
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.0591
    Cell Significance Index: -0.8300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0633
    Cell Significance Index: -3.2900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0698
    Cell Significance Index: -7.2700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0706
    Cell Significance Index: -3.2900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0780
    Cell Significance Index: -2.0100
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0801
    Cell Significance Index: -2.0000
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0809
    Cell Significance Index: -3.5200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0858
    Cell Significance Index: -2.3400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0878
    Cell Significance Index: -6.5400
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.1017
    Cell Significance Index: -1.3300
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: -0.1036
    Cell Significance Index: -1.7800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1078
    Cell Significance Index: -7.2500
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.1087
    Cell Significance Index: -2.7700
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.1119
    Cell Significance Index: -1.5900
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: -0.1124
    Cell Significance Index: -1.0200
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.1128
    Cell Significance Index: -1.4300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1132
    Cell Significance Index: -6.9600
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: -0.1168
    Cell Significance Index: -1.4100
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.1192
    Cell Significance Index: -1.9300
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.1207
    Cell Significance Index: -2.3600
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.1230
    Cell Significance Index: -1.4000
  • Cell Name: osteoblast (CL0000062)
    Fold Change: -0.1237
    Cell Significance Index: -1.2000
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.1371
    Cell Significance Index: -1.9900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1384
    Cell Significance Index: -5.0800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1408
    Cell Significance Index: -3.7600
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: -0.1415
    Cell Significance Index: -0.8900
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: -0.1422
    Cell Significance Index: -1.6100
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: -0.1438
    Cell Significance Index: -1.7000
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: -0.1438
    Cell Significance Index: -1.2800
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.1472
    Cell Significance Index: -1.6000
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: -0.1499
    Cell Significance Index: -1.5600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1575
    Cell Significance Index: -8.8400
  • Cell Name: suprabasal keratinocyte (CL4033013)
    Fold Change: -0.1611
    Cell Significance Index: -2.5900
  • Cell Name: myoblast (CL0000056)
    Fold Change: -0.1618
    Cell Significance Index: -1.5900
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.1661
    Cell Significance Index: -2.0200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1663
    Cell Significance Index: -5.7800
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: -0.1776
    Cell Significance Index: -0.8200
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.1783
    Cell Significance Index: -5.6400
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: -0.1811
    Cell Significance Index: -2.3400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** MMP3 exhibits several key characteristics that enable its diverse functions: 1. **Substrate specificity**: MMP3 has a broad substrate specificity, cleaving a wide range of ECM components, including collagens, elastin, and proteoglycans. 2. **Zinc binding**: MMP3 contains a zinc-binding site, which is essential for its catalytic activity. 3. **Serine-type endopeptidase activity**: MMP3 is a serine-type endopeptidase, which distinguishes it from other MMPs that exhibit aspartic acid or cysteine protease activity. 4. **Cellular localization**: MMP3 is expressed in various cell types, including erythrocytes, endothelial cells, megakaryocytes, and fibroblasts. **Pathways and Functions** MMP3 is involved in several signaling pathways and processes, including: 1. **Extracellular matrix degradation**: MMP3 plays a key role in the degradation of the ECM, facilitating cell migration, invasion, and tissue remodeling. 2. **Inflammation**: MMP3 is upregulated in inflammatory conditions, contributing to the degradation of the ECM and the promotion of inflammatory responses. 3. **Cancer**: MMP3 is overexpressed in various types of cancer, where it facilitates tumor invasion, metastasis, and angiogenesis. 4. **Cardiovascular disease**: MMP3 is involved in the pathogenesis of cardiovascular disease, including atherosclerosis and cardiac remodeling. 5. **Neuroinflammation**: MMP3 is upregulated in neuroinflammatory conditions, such as Alzheimer's disease and multiple sclerosis. **Clinical Significance** MMP3 has significant clinical implications, including: 1. **Cancer diagnosis and prognosis**: Elevated MMP3 levels are associated with poor prognosis and metastasis in various types of cancer. 2. **Cardiovascular disease**: MMP3 is a potential biomarker for cardiovascular disease, with elevated levels associated with increased cardiovascular risk. 3. **Inflammation**: MMP3 is a key player in inflammatory conditions, such as arthritis and inflammatory bowel disease. 4. **Neurodegenerative diseases**: MMP3 is involved in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease and multiple sclerosis. In conclusion, MMP3 is a multifunctional enzyme that plays a crucial role in various physiological and pathological processes, including inflammation, cancer, cardiovascular disease, and neuroinflammation. Its clinical significance is reflected in its association with various diseases and disorders, making it a valuable target for therapeutic interventions.

Genular Protein ID: 3059578464

Symbol: MMP3_HUMAN

Name: Stromelysin-1

UniProtKB Accession Codes:

P08254 B2R8B8 Q3B7S0 Q6GRF8

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 ChEBI 26 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 22 DrugCentral 1 EC 1 EMBL 15 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 29 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 12 KEGG 1 MANE-Select 1 MEROPS 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MoonProt 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 44 PDBsum 44 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 7 RefSeq 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3360803

Title: The complete primary structure of human matrix metalloproteinase-3. Identity with stromelysin.

PubMed ID: 3360803

DOI: 10.1016/s0021-9258(18)68705-8

PubMed ID: 3030290

Title: Comparison of human stromelysin and collagenase by cloning and sequence analysis.

PubMed ID: 3030290

DOI: 10.1042/bj2400913

PubMed ID: 3477804

Title: Human skin fibroblast stromelysin: structure, glycosylation, substrate specificity, and differential expression in normal and tumorigenic cells.

PubMed ID: 3477804

DOI: 10.1073/pnas.84.19.6725

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2383557

Title: Stepwise activation mechanisms of the precursor of matrix metalloproteinase 3 (stromelysin) by proteinases and (4-aminophenyl)mercuric acetate.

PubMed ID: 2383557

DOI: 10.1021/bi00476a020

PubMed ID: 1371271

Title: Matrix metalloproteinase 3 (stromelysin) activates the precursor for the human matrix metalloproteinase 9.

PubMed ID: 1371271

DOI: 10.1016/s0021-9258(19)50563-4

PubMed ID: 8662692

Title: Progression of coronary atherosclerosis is associated with a common genetic variant of the human stromelysin-1 promoter which results in reduced gene expression.

PubMed ID: 8662692

DOI: 10.1074/jbc.271.22.13055

PubMed ID: 11029580

Title: Prostromelysin-1 (proMMP-3) stimulates plasminogen activation by tissue-type plasminogen activator.

PubMed ID: 11029580

DOI: 10.1046/j.1432-1327.2000.01732.x

PubMed ID: 12477941

Title: Prediction of the risk of myocardial infarction from polymorphisms in candidate genes.

PubMed ID: 12477941

DOI: 10.1056/nejmoa021445

PubMed ID: 21330369

Title: Role of matrix metalloproteinase 3-mediated alpha-synuclein cleavage in dopaminergic cell death.

PubMed ID: 21330369

DOI: 10.1074/jbc.m111.222430

PubMed ID: 22265821

Title: Matrix metalloproteinase-3 is activated by HtrA2/Omi in dopaminergic cells: relevance to Parkinson's disease.

PubMed ID: 22265821

DOI: 10.1016/j.neuint.2012.01.001

PubMed ID: 35940311

Title: Matrix metalloproteinase 3 restricts viral infection by enhancing host antiviral immunity.

PubMed ID: 35940311

DOI: 10.1016/j.antiviral.2022.105388

PubMed ID: 7656014

Title: The NMR structure of the inhibited catalytic domain of human stromelysin-1.

PubMed ID: 7656014

DOI: 10.1038/nsb0294-111

PubMed ID: 9827994

Title: Solution structures of stromelysin complexed to thiadiazole inhibitors.

PubMed ID: 9827994

DOI: 10.1002/pro.5560071105

PubMed ID: 8535233

Title: Stromelysin-1: three-dimensional structure of the inhibited catalytic domain and of the C-truncated proenzyme.

PubMed ID: 8535233

DOI: 10.1002/pro.5560041002

PubMed ID: 8740360

Title: X-ray structure of a hydroxamate inhibitor complex of stromelysin catalytic domain and its comparison with members of the zinc metalloproteinase superfamily.

PubMed ID: 8740360

DOI: 10.1016/s0969-2126(96)00043-3

PubMed ID: 9083493

Title: Inhibition of stromelysin-1 (MMP-3) by P1'-biphenylylethyl carboxyalkyl dipeptides.

PubMed ID: 9083493

DOI: 10.1021/jm960465t

PubMed ID: 9288970

Title: Mechanism of inhibition of the human matrix metalloproteinase stromelysin-1 by TIMP-1.

PubMed ID: 9288970

DOI: 10.1038/37995

PubMed ID: 9792098

Title: Structural characterizations of nonpeptidic thiadiazole inhibitors of matrix metalloproteinases reveal the basis for stromelysin selectivity.

PubMed ID: 9792098

DOI: 10.1002/pro.5560071008

PubMed ID: 10543949

Title: Crystal structure of the stromelysin catalytic domain at 2.0-A resolution: inhibitor-induced conformational changes.

PubMed ID: 10543949

DOI: 10.1006/jmbi.1999.3147

PubMed ID: 10422833

Title: X-ray structure of human stromelysin catalytic domain complexed with nonpeptide inhibitors: implications for inhibitor selectivity.

PubMed ID: 10422833

DOI: 10.1110/ps.8.7.1455

PubMed ID: 9760240

Title: Solution structure of the catalytic domain of human stromelysin-1 complexed to a potent, nonpeptidic inhibitor.

PubMed ID: 9760240

DOI: 10.1021/bi981328w

Sequence Information:

  • Length: 477
  • Mass: 53977
  • Checksum: 96194833B907668D
  • Sequence:
    • MKSLPILLLL CVAVCSAYPL DGAARGEDTS MNLVQKYLEN YYDLKKDVKQ FVRRKDSGPV 
VKKIREMQKF LGLEVTGKLD SDTLEVMRKP RCGVPDVGHF RTFPGIPKWR KTHLTYRIVN 
YTPDLPKDAV DSAVEKALKV WEEVTPLTFS RLYEGEADIM ISFAVREHGD FYPFDGPGNV 
LAHAYAPGPG INGDAHFDDD EQWTKDTTGT NLFLVAAHEI GHSLGLFHSA NTEALMYPLY 
HSLTDLTRFR LSQDDINGIQ SLYGPPPDSP ETPLVPTEPV PPEPGTPANC DPALSFDAVS 
TLRGEILIFK DRHFWRKSLR KLEPELHLIS SFWPSLPSGV DAAYEVTSKD LVFIFKGNQF 
WAIRGNEVRA GYPRGIHTLG FPPTVRKIDA AISDKEKNKT YFFVEDKYWR FDEKRNSMEP 
GFPKQIAEDF PGIDSKIDAV FEEFGFFYFF TGSSQLEFDP NAKKVTHTLK SNSWLNC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.