Details for: MPP1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 44.4546
Cell Significance Index: -18.0600 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 42.6753
Cell Significance Index: -17.5800 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 38.4537
Cell Significance Index: -19.7800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 27.8344
Cell Significance Index: -7.0600 - Cell Name: basophilic erythroblast (CL0000549)
Fold Change: 20.0920
Cell Significance Index: 9.1500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 6.7678
Cell Significance Index: -18.1300 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 4.5451
Cell Significance Index: -17.9400 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 3.1794
Cell Significance Index: 49.1900 - Cell Name: liver dendritic cell (CL2000055)
Fold Change: 2.2821
Cell Significance Index: 6.0200 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 1.9177
Cell Significance Index: 35.4500 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.1380
Cell Significance Index: 68.3200 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 1.1213
Cell Significance Index: 30.0000 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.0329
Cell Significance Index: 66.6400 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.6055
Cell Significance Index: 98.4800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.5913
Cell Significance Index: 533.9200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.5305
Cell Significance Index: 106.4100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.5072
Cell Significance Index: 50.1700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.4732
Cell Significance Index: 32.7300 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.4511
Cell Significance Index: 5.5800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.4243
Cell Significance Index: 22.2800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.3431
Cell Significance Index: 17.8700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2686
Cell Significance Index: 7.7400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.2197
Cell Significance Index: 43.6000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2027
Cell Significance Index: 72.7200 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.1204
Cell Significance Index: 15.4400 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1167
Cell Significance Index: 80.7300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1107
Cell Significance Index: 15.2000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.1056
Cell Significance Index: 2.6400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1036
Cell Significance Index: 19.7100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0876
Cell Significance Index: 38.7400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.0777
Cell Significance Index: 8.9000 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0586
Cell Significance Index: 1.2700 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0355
Cell Significance Index: 19.4100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0228
Cell Significance Index: 3.9000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0183
Cell Significance Index: 0.8300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0117
Cell Significance Index: 0.4100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0079
Cell Significance Index: 0.2100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0002
Cell Significance Index: -0.4200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0017
Cell Significance Index: -0.1700 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0026
Cell Significance Index: -0.0500 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.0049
Cell Significance Index: -0.0400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0054
Cell Significance Index: -9.9600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0055
Cell Significance Index: -8.5200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0061
Cell Significance Index: -3.8200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0085
Cell Significance Index: -6.2600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0106
Cell Significance Index: -14.4200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0122
Cell Significance Index: -8.9100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0123
Cell Significance Index: -6.9400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0148
Cell Significance Index: -1.1400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0179
Cell Significance Index: -11.3800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0184
Cell Significance Index: -2.1700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0199
Cell Significance Index: -15.0300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0294
Cell Significance Index: -13.3300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0452
Cell Significance Index: -9.5100 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0596
Cell Significance Index: -6.8100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0627
Cell Significance Index: -11.3000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0649
Cell Significance Index: -18.6700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0692
Cell Significance Index: -10.0600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0733
Cell Significance Index: -4.9300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0776
Cell Significance Index: -4.7700 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0896
Cell Significance Index: -11.5800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0980
Cell Significance Index: -6.9300 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.1031
Cell Significance Index: -4.5600 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1053
Cell Significance Index: -2.6900 - Cell Name: precursor cell (CL0011115)
Fold Change: -0.1055
Cell Significance Index: -0.8000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1118
Cell Significance Index: -13.0300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.1130
Cell Significance Index: -13.8900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.1212
Cell Significance Index: -4.5900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1374
Cell Significance Index: -4.4000 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.1405
Cell Significance Index: -2.9400 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.1517
Cell Significance Index: -1.5700 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1615
Cell Significance Index: -10.1800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1647
Cell Significance Index: -17.1500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1722
Cell Significance Index: -8.0300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1866
Cell Significance Index: -14.7800 - Cell Name: early promyelocyte (CL0002154)
Fold Change: -0.1895
Cell Significance Index: -1.2100 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2082
Cell Significance Index: -15.5200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.2137
Cell Significance Index: -13.1000 - Cell Name: megakaryocyte progenitor cell (CL0000553)
Fold Change: -0.2156
Cell Significance Index: -1.5500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.2240
Cell Significance Index: -6.2600 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.2258
Cell Significance Index: -3.8700 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.2259
Cell Significance Index: -5.9400 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.2332
Cell Significance Index: -6.8500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.2368
Cell Significance Index: -13.2900 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.2422
Cell Significance Index: -3.6500 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.2583
Cell Significance Index: -4.5700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2606
Cell Significance Index: -12.2500 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.3143
Cell Significance Index: -8.9700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.3167
Cell Significance Index: -16.4500 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.3171
Cell Significance Index: -6.7300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.3863
Cell Significance Index: -9.9300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.3933
Cell Significance Index: -10.7100 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.4044
Cell Significance Index: -12.8800 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.4051
Cell Significance Index: -6.7800 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.4161
Cell Significance Index: -21.0300 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.4191
Cell Significance Index: -10.0500 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.4252
Cell Significance Index: -13.9200 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.4253
Cell Significance Index: -14.7800 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.4296
Cell Significance Index: -15.0500 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.4350
Cell Significance Index: -15.9700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1488428059
Symbol: EM55_HUMAN
Name: 55 kDa erythrocyte membrane protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1713685
Title: Molecular identification of a major palmitoylated erythrocyte membrane protein containing the src homology 3 motif.
PubMed ID: 1713685
PubMed ID: 1301163
Title: The gene encoding the palmitoylated erythrocyte membrane protein, p55, originates at the CpG island 3' to the factor VIII gene.
PubMed ID: 1301163
DOI: 10.1093/hmg/1.2.97
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15772651
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17584769
Title: MPP1 links the Usher protein network and the Crumbs protein complex in the retina.
PubMed ID: 17584769
DOI: 10.1093/hmg/ddm147
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19144871
Title: Identification of erythrocyte p55/MPP1 as a binding partner of NF2 tumor suppressor protein/Merlin.
PubMed ID: 19144871
DOI: 10.3181/0809-rm-275
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22496366
Title: Palmitoylation of MPP1 (membrane-palmitoylated protein 1)/p55 is crucial for lateral membrane organization in erythroid cells.
PubMed ID: 22496366
PubMed ID: 29475958
Title: Palmitoylation of MPP1 (membrane-palmitoylated protein 1)/p55 is crucial for lateral membrane organization in erythroid cells.
PubMed ID: 29475958
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 16741958
Title: Solution structure of human erythroid p55 PDZ domain.
PubMed ID: 16741958
DOI: 10.1002/prot.21028
Sequence Information:
- Length: 466
- Mass: 52296
- Checksum: DC68AA68EF48A26E
- Sequence:
MTLKASEGES GGSMHTALSD LYLEHLLQKR SRPEAVSHPL NTVTEDMYTN GSPAPGSPAQ VKGQEVRKVR LIQFEKVTEE PMGITLKLNE KQSCTVARIL HGGMIHRQGS LHVGDEILEI NGTNVTNHSV DQLQKAMKET KGMISLKVIP NQQSRLPALQ MFMRAQFDYD PKKDNLIPCK EAGLKFATGD IIQIINKDDS NWWQGRVEGS SKESAGLIPS PELQEWRVAS MAQSAPSEAP SCSPFGKKKK YKDKYLAKHS SIFDQLDVVS YEEVVRLPAF KRKTLVLIGA SGVGRSHIKN ALLSQNPEKF VYPVPYTTRP PRKSEEDGKE YHFISTEEMT RNISANEFLE FGSYQGNMFG TKFETVHQIH KQNKIAILDI EPQTLKIVRT AELSPFIVFI APTDQGTQTE ALQQLQKDSE AIRSQYAHYF DLSLVNNGVD ETLKKLQEAF DQACSSPQWV PVSWVY
Genular Protein ID: 3265659268
Symbol: B4E325_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 449
- Mass: 50154
- Checksum: B3089699935612ED
- Sequence:
MTLKASEGES GGSMHTALSD LYLEHLLQKR SRPEAVSHPL NTVTEDMYTN GSPAPGSPAQ VKGQEGITLK LNEKQSCTVA RILHGGMIHR QGSLHVGDEI LEINGTNVTN HSVDQLQKAM KETKGMISLK VIPNQQSRLP ALQMFMRAQF DYDPKKDNLI PCKEAGLKFA TGDIIQIINK DDSNWWQGRV EGSSKESAGL IPSPELQEWR VASMAQSAPS EAPSCSPFGK KKKYKDKYLA KHSSIFDQLD VVSYEEVVRL PAFKRKTLVL IGASGVGRSH IKNALLSQNP EKFVYPVPYT TRPPRKSEED GKEYHFISTE EMTRNISANE FLEFGSYQGN MFGTKFETVH QIHKQNKIAI LDIEPQTLKI VRTAELSPFI VFIAPTDQGT QTEALQQLQK DSEAIRSQYA HYFDLSLVNN GVDETLKKLQ EAFGQACSSP QWVPVSWVY
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.