Details for: MPP3
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 52.0416
Cell Significance Index: -13.2000 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 27.5195
Cell Significance Index: -11.1800 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 11.7152
Cell Significance Index: -11.1900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 4.0064
Cell Significance Index: 307.4500 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 3.3538
Cell Significance Index: -7.3400 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 1.9723
Cell Significance Index: 33.8000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 1.1457
Cell Significance Index: 70.2400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.5951
Cell Significance Index: 17.1500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.5410
Cell Significance Index: 102.9600 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.4550
Cell Significance Index: 20.6200 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.3945
Cell Significance Index: 39.0300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.3589
Cell Significance Index: 10.0300 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.2695
Cell Significance Index: 5.9000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.2660
Cell Significance Index: 16.3500 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.2608
Cell Significance Index: 3.8500 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.2359
Cell Significance Index: 5.1100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2133
Cell Significance Index: 192.5700 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.2069
Cell Significance Index: 12.4200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.2005
Cell Significance Index: 39.7800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.1893
Cell Significance Index: 20.5900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.1864
Cell Significance Index: 30.3200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.1700
Cell Significance Index: 2.3200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.1514
Cell Significance Index: 30.3800 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1319
Cell Significance Index: 91.2400 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.1264
Cell Significance Index: 3.4400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.1188
Cell Significance Index: 6.2400 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1005
Cell Significance Index: 3.5300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.0987
Cell Significance Index: 5.5400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.0948
Cell Significance Index: 11.0500 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0696
Cell Significance Index: 1.7400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0673
Cell Significance Index: 42.7200 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 0.0667
Cell Significance Index: 1.0100 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.0551
Cell Significance Index: 2.8700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0525
Cell Significance Index: 18.8200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0219
Cell Significance Index: 1.5200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0166
Cell Significance Index: 31.2300 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0077
Cell Significance Index: 3.4000 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.0075
Cell Significance Index: 0.1800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0036
Cell Significance Index: 6.7100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0016
Cell Significance Index: 2.4100 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0019
Cell Significance Index: -1.0600 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0037
Cell Significance Index: -1.6600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0090
Cell Significance Index: -0.4200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0095
Cell Significance Index: -12.8600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0116
Cell Significance Index: -0.7800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0156
Cell Significance Index: -11.8200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0160
Cell Significance Index: -2.3200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0175
Cell Significance Index: -12.9300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0179
Cell Significance Index: -13.1300 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0217
Cell Significance Index: -0.4500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0232
Cell Significance Index: -13.0800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0235
Cell Significance Index: -14.6500 - Cell Name: stellate neuron (CL0000122)
Fold Change: -0.0308
Cell Significance Index: -0.3500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0313
Cell Significance Index: -5.6400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0375
Cell Significance Index: -4.6100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0377
Cell Significance Index: -10.8600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0410
Cell Significance Index: -4.7000 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0431
Cell Significance Index: -5.5300 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0444
Cell Significance Index: -5.7300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0450
Cell Significance Index: -1.4400 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0521
Cell Significance Index: -8.8900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0521
Cell Significance Index: -7.1500 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0661
Cell Significance Index: -1.2900 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.0683
Cell Significance Index: -1.4300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0699
Cell Significance Index: -14.7200 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0784
Cell Significance Index: -1.6700 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.0823
Cell Significance Index: -1.7600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0823
Cell Significance Index: -6.1400 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0837
Cell Significance Index: -5.9200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1107
Cell Significance Index: -5.7500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1117
Cell Significance Index: -5.2500 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1128
Cell Significance Index: -3.9200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1152
Cell Significance Index: -11.9900 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1161
Cell Significance Index: -11.8600 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.1475
Cell Significance Index: -2.1000 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.1677
Cell Significance Index: -2.1500 - Cell Name: helper T cell (CL0000912)
Fold Change: -0.1964
Cell Significance Index: -2.7900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.2029
Cell Significance Index: -12.7900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.2032
Cell Significance Index: -2.9100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.2118
Cell Significance Index: -9.3700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.2153
Cell Significance Index: -13.8900 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.2199
Cell Significance Index: -3.6800 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.2264
Cell Significance Index: -5.8200 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: -0.2275
Cell Significance Index: -2.3700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.2398
Cell Significance Index: -9.0800 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.2537
Cell Significance Index: -7.2400 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.2575
Cell Significance Index: -9.0200 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2581
Cell Significance Index: -8.4500 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.2659
Cell Significance Index: -3.8300 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.2826
Cell Significance Index: -9.0000 - Cell Name: granule cell (CL0000120)
Fold Change: -0.2872
Cell Significance Index: -3.2700 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.2907
Cell Significance Index: -7.7900 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.2911
Cell Significance Index: -7.0500 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.3004
Cell Significance Index: -7.9000 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.3053
Cell Significance Index: -6.4800 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.3209
Cell Significance Index: -11.7800 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.3345
Cell Significance Index: -9.5900 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: -0.3367
Cell Significance Index: -4.2400 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.3383
Cell Significance Index: -6.6900 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.3449
Cell Significance Index: -3.7500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3603732582
Symbol: MPP3_HUMAN
Name: Discs large homolog 3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8824795
Title: Isolation of a gene (DLG3) encoding a second member of the discs-large family on chromosome 17q12-q21.
PubMed ID: 8824795
PubMed ID: 16519681
Title: MPP3 is recruited to the MPP5 protein scaffold at the retinal outer limiting membrane.
PubMed ID: 16519681
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 13679854
Title: Association of a lung tumor suppressor TSLC1 with MPP3, a human homologue of Drosophila tumor suppressor Dlg.
PubMed ID: 13679854
PubMed ID: 24503895
Title: Trans-homophilic interaction of CADM1 activates PI3K by forming a complex with MAGuK-family proteins MPP3 and Dlg.
PubMed ID: 24503895
PubMed ID: 25268382
Title: Trans-homophilic interaction of CADM1 activates PI3K by forming a complex with MAGuK-family proteins MPP3 and Dlg.
PubMed ID: 25268382
Sequence Information:
- Length: 585
- Mass: 66152
- Checksum: 782DAE54096A4993
- Sequence:
MPVLSEDSGL HETLALLTSQ LRPDSNHKEE MGFLRDVFSE KSLSYLMKIH EKLRYYERQS PTPVLHSAVA LAEDVMEELQ AASVHSDERE LLQLLSTPHL RAVLMVHDTV AQKNFDPVLP PLPDNIDEDF DEESVKIVRL VKNKEPLGAT IRRDEHSGAV VVARIMRGGA ADRSGLVHVG DELREVNGIA VLHKRPDEIS QILAQSQGSI TLKIIPATQE EDRLKESKVF MRALFHYNPR EDRAIPCQEA GLPFQRRQVL EVVSQDDPTW WQAKRVGDTN LRAGLIPSKG FQERRLSYRR AAGTLPSPQS LRKPPYDQPC DKETCDCEGY LKGHYVAGLR RSFRLGCRER LGGSQEGKMS SGAESPELLT YEEVARYQHQ PGERPRLVVL IGSLGARLHE LKQKVVAENP QHFGVAVPHT TRPRKSHEKE GVEYHFVSKQ AFEADLHHNK FLEHGEYKEN LYGTSLEAIQ AVMAKNKVCL VDVEPEALKQ LRTSEFKPYI IFVKPAIQEK RKTPPMSPAC EDTAAPFDEQ QQEMAASAAF IDRHYGHLVD AVLVKEDLQG AYSQLKVVLE KLSKDTHWVP VSWVR
Genular Protein ID: 1003080654
Symbol: D3DX46_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 11181995
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
Sequence Information:
- Length: 610
- Mass: 68889
- Checksum: EF72998CA9F5D5D7
- Sequence:
MELQYPPPPP SPRICRERSG GDNASMPVLS EDSGLHETLA LLTSQLRPDS NHKEEMGFLR DVFSEKSLSY LMKIHEKLRY YERQSPTPVL HSAVALAEDV MEELQAASVH SDERELLQLL STPHLRAVLM VHDTVAQKNF DPVLPPLPDN IDEDFDEESV KIVRLVKNKE PLGATIRRDE HSGAVVVARI MRGGAADRSG LVHVGDELRE VNGIAVLHKR PDEISQILAQ SQGSITLKII PATQEEDRLK ESKVFMRALF HYNPREDRAI PCQEAGLPFQ RRQVLEVVSQ DDPTWWQAKR VGDTNLRAGL IPSKGFQERR LSYRRAAGTL PSPQSLRKPP YDQPCDKETC DCEGYLKGHY VAGLRRSFRL GCRERLGGSQ EGKMSSGAES PELLTYEEVA RYQHQPGERP RLVVLIGSLG ARLHELKQKV VAENPQHFGV AVPHTTRPRK SHEKEGVEYH FVSKQAFEAD LHHNKFLEHG EYKENLYGTS LEAIQAVMAK NKVCLVDVEP EALKQLRTSE FKPYIIFVKP AIQEKRKTPP MSPACEDTAA PFDEQQQEMA ASAAFIDRHY GHLVDAVLVK EDLQGAYSQL KVVLEKLSKD THWVPVSWVR
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.