Details for: MST1

Gene ID: 4485

Symbol: MST1

Ensembl ID: ENSG00000173531

Description: macrophage stimulating 1

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 3.11
    Marker Score: 10,176
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 2.51
    Marker Score: 13,490
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.84
    Marker Score: 7,953
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.78
    Marker Score: 11,424
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 1.45
    Marker Score: 341
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.33
    Marker Score: 887
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.13
    Marker Score: 1,214
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.04
    Marker Score: 251,794
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,811
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48,036
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,407
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.97
    Marker Score: 500
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.96
    Marker Score: 453
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.96
    Marker Score: 655
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,411
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 0.92
    Marker Score: 712
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,734
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.91
    Marker Score: 5,178
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.91
    Marker Score: 1,472
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.88
    Marker Score: 318
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,296
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 0.86
    Marker Score: 3,053
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 0.86
    Marker Score: 2,339
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.85
    Marker Score: 1,484
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 0.84
    Marker Score: 901
  • Cell Name: inflammatory macrophage (CL0000863)
    Fold Change: 0.81
    Marker Score: 251
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 0.78
    Marker Score: 2,090
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.77
    Marker Score: 818
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.77
    Marker Score: 1,614
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.76
    Marker Score: 582
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.75
    Marker Score: 388
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.71
    Marker Score: 652
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 0.71
    Marker Score: 1,786
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.7
    Marker Score: 282
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.7
    Marker Score: 1,644
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.68
    Marker Score: 174
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 0.67
    Marker Score: 710
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.66
    Marker Score: 2,788
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 0.65
    Marker Score: 235
  • Cell Name: precursor cell (CL0011115)
    Fold Change: 0.64
    Marker Score: 156
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.63
    Marker Score: 2,346
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 0.62
    Marker Score: 121
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 0.6
    Marker Score: 332
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: 0.6
    Marker Score: 240
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 0.59
    Marker Score: 2,833
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.57
    Marker Score: 1,953
  • Cell Name: Unknown (CL0002371)
    Fold Change: 0.56
    Marker Score: 596
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.56
    Marker Score: 444
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 0.54
    Marker Score: 173
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 0.52
    Marker Score: 751
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.52
    Marker Score: 887
  • Cell Name: enterocyte of colon (CL1000347)
    Fold Change: 0.52
    Marker Score: 797
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.52
    Marker Score: 330
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 0.5
    Marker Score: 137
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.5
    Marker Score: 4,998
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 0.49
    Marker Score: 689
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 0.48
    Marker Score: 1,508
  • Cell Name: paneth cell (CL0000510)
    Fold Change: 0.47
    Marker Score: 327
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 0.46
    Marker Score: 760
  • Cell Name: renal alpha-intercalated cell (CL0005011)
    Fold Change: 0.46
    Marker Score: 240
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.45
    Marker Score: 187
  • Cell Name: nasal mucosa goblet cell (CL0002480)
    Fold Change: 0.45
    Marker Score: 298
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.44
    Marker Score: 165
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 0.42
    Marker Score: 157
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: 0.41
    Marker Score: 458
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.39
    Marker Score: 6,915
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 0.37
    Marker Score: 370
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 0.37
    Marker Score: 372
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 0.36
    Marker Score: 134
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 0.34
    Marker Score: 140
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.33
    Marker Score: 359
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.33
    Marker Score: 2,115
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.32
    Marker Score: 242
  • Cell Name: epithelial cell of glomerular capsule (CL1000450)
    Fold Change: 0.32
    Marker Score: 82
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.32
    Marker Score: 320
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 0.32
    Marker Score: 6,798
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.32
    Marker Score: 1,875
  • Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
    Fold Change: 0.32
    Marker Score: 106
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.31
    Marker Score: 289
  • Cell Name: progenitor cell of endocrine pancreas (CL0002351)
    Fold Change: 0.3
    Marker Score: 66
  • Cell Name: M cell of gut (CL0000682)
    Fold Change: 0.3
    Marker Score: 77
  • Cell Name: promyelocyte (CL0000836)
    Fold Change: 0.29
    Marker Score: 142
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.29
    Marker Score: 76
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.28
    Marker Score: 289
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.28
    Marker Score: 162
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.28
    Marker Score: 240
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.28
    Marker Score: 1,159
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.27
    Marker Score: 357
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.26
    Marker Score: 299
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.26
    Marker Score: 85
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 0.26
    Marker Score: 184
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.26
    Marker Score: 311
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 0.25
    Marker Score: 248
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.25
    Marker Score: 104
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 0.25
    Marker Score: 1,836
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.24
    Marker Score: 192
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: 0.24
    Marker Score: 117
  • Cell Name: enterocyte of epithelium proper of ileum (CL1000342)
    Fold Change: 0.24
    Marker Score: 68
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 0.23
    Marker Score: 80
  • Cell Name: pulmonary ionocyte (CL0017000)
    Fold Change: 0.23
    Marker Score: 140

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Expression Pattern:** MST1 is widely expressed in various tissues, including the liver, kidney, reproductive organs, and immune cells. 2. **Signaling Pathways:** MST1 is involved in multiple signaling pathways, including receptor tyrosine kinase binding, regulation of camp-dependent protein kinase activity, and negative regulation of gluconeogenesis. 3. **Cell Type-Specific Expression:** MST1 is highly expressed in hepatocytes, nephron tubule epithelial cells, and immune cells such as macrophages and endothelial cells. 4. **Protein Interactions:** MST1 interacts with various proteins, including hepatocyte growth factor-like protein (HGFL), which is involved in cell proliferation and differentiation. **Pathways and Functions:** 1. **Receptor Tyrosine Kinase Binding:** MST1 binds to receptor tyrosine kinases, such as c-Met and Axl, to regulate cell signaling and proliferation. 2. **Regulation of Camp-Dependent Protein Kinase Activity:** MST1 regulates the activity of camp-dependent protein kinase (PKA), which is involved in various cellular processes, including cell proliferation and differentiation. 3. **Negative Regulation of Gluconeogenesis:** MST1 negatively regulates gluconeogenesis, a process that generates glucose from non-carbohydrate sources, which is essential for maintaining glucose homeostasis. 4. **Signaling by MST1:** MST1 signals through various pathways, including the PI3K/AKT and MAPK/ERK pathways, to regulate cell growth, differentiation, and survival. 5. **Regulation of Receptor Signaling Pathway via Jak-Stat:** MST1 regulates the receptor signaling pathway via the Jak-Stat pathway, which is involved in immune responses and inflammation. **Clinical Significance:** 1. **Cancer:** MST1 is overexpressed in various types of cancer, including breast, lung, and liver cancer, where it promotes tumor growth, metastasis, and resistance to therapy. 2. **Autoimmune Disorders:** MST1 is involved in the pathogenesis of autoimmune disorders, such as rheumatoid arthritis and lupus, where it regulates immune cell function and inflammation. 3. **Metabolic Disorders:** MST1 is involved in the regulation of glucose metabolism and insulin signaling, which is essential for maintaining glucose homeostasis and preventing metabolic disorders, such as type 2 diabetes. 4. **Neurological Disorders:** MST1 is involved in the regulation of neuronal function and survival, which is essential for maintaining neurological homeostasis and preventing disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, MST1 is a multifaceted gene that plays a crucial role in various cellular processes, including immune regulation, cell signaling, and tissue homeostasis. Its involvement in multiple signaling pathways and diseases underscores its complexity and versatility, making it an attractive target for therapeutic intervention in various diseases.

Genular Protein ID: 3032797769

Symbol: HGFL_HUMAN

Name: Hepatocyte growth factor-like protein

UniProtKB Accession Codes:

P26927 A6NLA3 A8MSX3 Q13350 Q14870 Q6GTN4

Database IDs:

AGR 1 AlphaFoldDB 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CDD 3 CPTAC 1 CPTC 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 EvolutionaryTrace 1 GO 8 Gene3D 3 GeneCards 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MEROPS 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 2 PIR 1 PIRSF 2 PRINTS 2 PRO 1 PROSITE 4 PROSITE-ProRule 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1655021

Title: Characterization of the DNF15S2 locus on human chromosome 3: identification of a gene coding for four kringle domains with homology to hepatocyte growth factor.

PubMed ID: 1655021

DOI: 10.1021/bi00104a029

PubMed ID: 8393443

Title: Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins and locates the MSP gene on chromosome 3.

PubMed ID: 8393443

DOI: 10.1016/s0021-9258(18)82279-7

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1827141

Title: Macrophage stimulating protein: purification, partial amino acid sequence, and cellular activity.

PubMed ID: 1827141

DOI: 10.1084/jem.173.5.1227

PubMed ID: 9202013

Title: Macrophage stimulating protein (MSP) binds to its receptor via the MSP beta chain.

PubMed ID: 9202013

DOI: 10.1074/jbc.272.27.16999

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 19079170

Title: Gene-centric association mapping of chromosome 3p implicates MST1 in IBD pathogenesis.

PubMed ID: 19079170

DOI: 10.1038/mi.2007.15

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 20228799

Title: Genome-wide association identifies multiple ulcerative colitis susceptibility loci.

PubMed ID: 20228799

DOI: 10.1038/ng.549

PubMed ID: 21875933

Title: Proteolytic activation of pro-macrophage-stimulating protein by hepsin.

PubMed ID: 21875933

DOI: 10.1158/1541-7786.mcr-11-0004

PubMed ID: 22087277

Title: Protein characterization of a candidate mechanism SNP for Crohn's disease: the macrophage stimulating protein R689C substitution.

PubMed ID: 22087277

DOI: 10.1371/journal.pone.0027269

PubMed ID: 16279944

Title: Crystal structure of the beta-chain of human hepatocyte growth factor-like/macrophage stimulating protein.

PubMed ID: 16279944

DOI: 10.1111/j.1742-4658.2005.04968.x

Sequence Information:

  • Length: 711
  • Mass: 80320
  • Checksum: 2E4B3C7D4AA9B566
  • Sequence:
    • MGWLPLLLLL TQCLGVPGQR SPLNDFQVLR GTELQHLLHA VVPGPWQEDV ADAEECAGRC 
GPLMDCRAFH YNVSSHGCQL LPWTQHSPHT RLRRSGRCDL FQKKDYVRTC IMNNGVGYRG 
TMATTVGGLP CQAWSHKFPN DHKYTPTLRN GLEENFCRNP DGDPGGPWCY TTDPAVRFQS 
CGIKSCREAA CVWCNGEEYR GAVDRTESGR ECQRWDLQHP HQHPFEPGKF LDQGLDDNYC 
RNPDGSERPW CYTTDPQIER EFCDLPRCGS EAQPRQEATT VSCFRGKGEG YRGTANTTTA 
GVPCQRWDAQ IPHQHRFTPE KYACKDLREN FCRNPDGSEA PWCFTLRPGM RAAFCYQIRR 
CTDDVRPQDC YHGAGEQYRG TVSKTRKGVQ CQRWSAETPH KPQFTFTSEP HAQLEENFCR 
NPDGDSHGPW CYTMDPRTPF DYCALRRCAD DQPPSILDPP DQVQFEKCGK RVDRLDQRRS 
KLRVVGGHPG NSPWTVSLRN RQGQHFCGGS LVKEQWILTA RQCFSSCHMP LTGYEVWLGT 
LFQNPQHGEP SLQRVPVAKM VCGPSGSQLV LLKLERSVTL NQRVALICLP PEWYVVPPGT 
KCEIAGWGET KGTGNDTVLN VALLNVISNQ ECNIKHRGRV RESEMCTEGL LAPVGACEGD 
YGGPLACFTH NCWVLEGIII PNRVCARSRW PAVFTRVSVF VDWIHKVMRL G

Genular Protein ID: 50203111

Symbol: Q53GN8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q53GN8

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 DNASU 1 EMBL 2 GO 3 Gene3D 3 Genevisible 1 GenomeRNAi 1 InterPro 11 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 2 PRINTS 2 PROSITE 7 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 1 SAM 1 SMART 3 SUPFAM 3

Citations:

PubMed ID: 8125298

Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.

PubMed ID: 8125298

DOI: 10.1016/0378-1119(94)90802-8

PubMed ID: 9373149

Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.

PubMed ID: 9373149

DOI: 10.1016/S0378-1119(97)00411-3

Sequence Information:

  • Length: 711
  • Mass: 80350
  • Checksum: 2E4B3C7D4AAF9593
  • Sequence:
    • MGWLPLLLLL TQCLGVPGQR SPLNDFQVLR GTELQHLLHA VVPGPWQEDV ADAEECAGRC 
GPLMDCRAFH YNVSSHGCQL LPWTQHSPHT RLRRSGRCDL FQKKDYVRTC IMNNGVGYRG 
TMATTVGGLP CQAWSHKFPN DHKYTPTLRN GLEENFCRNP DGDPGGPWCY TTDPAVRFQS 
CGIKSCREAA CVWCNGEEYR GTVDRTESGR ECQRWDLQHP HQHPFEPGKF LDQGLDDNYC 
RNPDGSERPW CYTTDPQIER EFCDLPRCGS EAQPRQEATT VSCFRGKGEG YRGTANTTTA 
GVPCQRWDAQ IPHQHRFTPE KYACKDLREN FCRNPDGSEA PWCFTLRPGM RAAFCYQIRR 
CTDDVRPQDC YHGAGEQYRG TVSKTRKGVQ CQRWSAETPH KPQFTFTSEP HAQLEENFCR 
NPDGDSHGPW CYTMDPRTPF DYCALRRCAD DQPPSILDPP DQVQFEKCGK RVDRLDQRRS 
KLRVVGGHPG NSPWTVSLRN RQGQHFCGGS LVKEQWILTA RQCFSSCHMP LTGYEVWLGT 
LFQNPQHGEP SLQRVPVAKM VCGPSGSQLV LLKLERSVTL NQRVALICLP PEWYVVPPGT 
KCEIAGWGET KGTGNDTVLN VALLNVISNQ ECNIKHRGRV RESEMCTEGL LAPVGACEGD 
YGGPLACFTH NCWVLEGIII PNRVCARSRW PAVFTRVSVF VDWIHKVMRL G

Genular Protein ID: 792949311

Symbol: G3XAK1_HUMAN

Name: N/A

UniProtKB Accession Codes:

G3XAK1

Database IDs:

ARBA 2 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 EMBL 3 Ensembl 2 GO 18 Gene3D 3 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 11 KEGG 1 MANE-Select 1 MEROPS 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 2 PRINTS 2 PROSITE 7 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 3 SUPFAM 3 TreeFam 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

Sequence Information:

  • Length: 725
  • Mass: 81999
  • Checksum: B222E0BDAC020D03
  • Sequence:
    • MGLWWVTVQP PARRMGWLPL LLLLTQCLGV PGQRSPLNDF QVLRGTELQH LLHAVVPGPW 
QEDVADAEEC AGRCGPLMDC RAFHYNVSSH GCQLLPWTQH SPHTRLRRSG RCDLFQKKDY 
VRTCIMNNGV GYRGTMATTV GGLPCQAWSH KFPNDHKYTP TLRNGLEENF CRNPDGDPGG 
PWCYTTDPAV RFQSCGIKSC REAACVWCNG EEYRGAVDRT ESGRECQRWD LQHPHQHPFE 
PGKFLDQGLD DNYCRNPDGS ERPWCYTTDP QIEREFCDLP RCGSEAQPRQ EATTVSCFRG 
KGEGYRGTAN TTTAGVPCQR WDAQIPHQHR FTPEKYACKD LRENFCRNPD GSEAPWCFTL 
RPGMRAAFCY QIRRCTDDVR PQDCYHGAGE QYRGTVSKTR KGVQCQRWSA ETPHKPQFTF 
TSEPHAQLEE NFCRNPDGDS HGPWCYTMDP RTPFDYCALR RCADDQPPSI LDPPDQVQFE 
KCGKRVDRLD QRRSKLRVVG GHPGNSPWTV SLRNRQGQHF CGGSLVKEQW ILTARQCFSS 
CHMPLTGYEV WLGTLFQNPQ HGEPSLQRVP VAKMVCGPSG SQLVLLKLER SVTLNQRVAL 
ICLPPEWYVV PPGTKCEIAG WGETKGTGND TVLNVALLNV ISNQECNIKH RGRVRESEMC 
TEGLLAPVGA CEGDYGGPLA CFTHNCWVLE GIIIPNRVCA RSRWPAVFTR VSVFVDWIHK 
VMRLG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.