Details for: MST1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 27.1304
Cell Significance Index: -4.2200 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 24.6409
Cell Significance Index: -6.2500 - Cell Name: liver dendritic cell (CL2000055)
Fold Change: 5.3413
Cell Significance Index: 14.0900 - Cell Name: kidney cell (CL1000497)
Fold Change: 4.3429
Cell Significance Index: 34.6800 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 4.2662
Cell Significance Index: -5.2600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 3.0069
Cell Significance Index: 572.2200 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 2.2259
Cell Significance Index: 37.5000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 1.6105
Cell Significance Index: -6.3600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.5980
Cell Significance Index: 1442.8400 - Cell Name: intrahepatic cholangiocyte (CL0002538)
Fold Change: 1.5944
Cell Significance Index: 6.0100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.5094
Cell Significance Index: 43.4900 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.4183
Cell Significance Index: 38.0100 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: 1.3909
Cell Significance Index: 22.9200 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 1.2111
Cell Significance Index: 5.8900 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.1946
Cell Significance Index: 71.7200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.1824
Cell Significance Index: 128.6100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.1064
Cell Significance Index: 219.5600 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.9978
Cell Significance Index: 162.2900 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 0.8130
Cell Significance Index: 12.0000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.6865
Cell Significance Index: 47.4800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.3621
Cell Significance Index: 10.1200 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 0.3134
Cell Significance Index: 1.8100 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.2967
Cell Significance Index: 13.4500 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.2683
Cell Significance Index: 5.8800 - Cell Name: Leydig cell (CL0000178)
Fold Change: 0.2445
Cell Significance Index: 1.2200 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 0.2311
Cell Significance Index: 2.9600 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.2225
Cell Significance Index: 5.8500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.2211
Cell Significance Index: 7.7700 - Cell Name: epidermal cell (CL0000362)
Fold Change: 0.2173
Cell Significance Index: 0.4900 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 0.2161
Cell Significance Index: 1.7900 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 0.2130
Cell Significance Index: 2.3300 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.2025
Cell Significance Index: 20.0300 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.1840
Cell Significance Index: 2.5100 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.1819
Cell Significance Index: 1.1300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.1744
Cell Significance Index: 9.0600 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.1165
Cell Significance Index: 4.0500 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.1018
Cell Significance Index: 13.0500 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0995
Cell Significance Index: 2.1200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0982
Cell Significance Index: 17.7000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0968
Cell Significance Index: 52.8800 - Cell Name: columnar/cuboidal epithelial cell (CL0000075)
Fold Change: 0.0966
Cell Significance Index: 0.3700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0685
Cell Significance Index: 9.4100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0545
Cell Significance Index: 24.0800 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.0536
Cell Significance Index: 0.8300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.0524
Cell Significance Index: 1.4300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0491
Cell Significance Index: 9.8500 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 0.0485
Cell Significance Index: 0.6800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0478
Cell Significance Index: 2.9400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0464
Cell Significance Index: 1.1600 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 0.0464
Cell Significance Index: 0.3600 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.0405
Cell Significance Index: 0.6500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0282
Cell Significance Index: 10.1300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0234
Cell Significance Index: 17.1800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0206
Cell Significance Index: 2.5300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.0189
Cell Significance Index: 0.8900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0174
Cell Significance Index: 2.9700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0137
Cell Significance Index: 25.7400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0119
Cell Significance Index: 18.3500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0116
Cell Significance Index: 21.3500 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.0082
Cell Significance Index: 0.0900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.0059
Cell Significance Index: 0.0900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.0017
Cell Significance Index: 0.2000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0002
Cell Significance Index: -0.1200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0014
Cell Significance Index: -1.8700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0021
Cell Significance Index: -1.5900 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0031
Cell Significance Index: -0.4000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0064
Cell Significance Index: -0.3000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0074
Cell Significance Index: -5.5000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0091
Cell Significance Index: -1.3300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0094
Cell Significance Index: -0.9600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0096
Cell Significance Index: -5.4400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0100
Cell Significance Index: -4.5300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0107
Cell Significance Index: -6.6800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0150
Cell Significance Index: -4.3300 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0167
Cell Significance Index: -0.2800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0191
Cell Significance Index: -1.3500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0199
Cell Significance Index: -1.4800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0293
Cell Significance Index: -1.8500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0316
Cell Significance Index: -3.6800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0318
Cell Significance Index: -6.7000 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.0336
Cell Significance Index: -0.9900 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0355
Cell Significance Index: -2.8100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0381
Cell Significance Index: -1.2200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0420
Cell Significance Index: -4.9500 - Cell Name: cholangiocyte (CL1000488)
Fold Change: -0.0426
Cell Significance Index: -0.4200 - Cell Name: peg cell (CL4033014)
Fold Change: -0.0446
Cell Significance Index: -1.0300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0453
Cell Significance Index: -2.5400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0455
Cell Significance Index: -3.5000 - Cell Name: fast muscle cell (CL0000190)
Fold Change: -0.0473
Cell Significance Index: -0.6200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0512
Cell Significance Index: -5.3300 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.0569
Cell Significance Index: -1.1900 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: -0.0600
Cell Significance Index: -0.5100 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: -0.0602
Cell Significance Index: -0.4600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0682
Cell Significance Index: -1.8200 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0682
Cell Significance Index: -3.5800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0712
Cell Significance Index: -3.1500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0732
Cell Significance Index: -4.9200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0786
Cell Significance Index: -4.8200 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0856
Cell Significance Index: -5.5200 - Cell Name: proerythroblast (CL0000547)
Fold Change: -0.0935
Cell Significance Index: -1.3400
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3032797769
Symbol: HGFL_HUMAN
Name: Hepatocyte growth factor-like protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1655021
Title: Characterization of the DNF15S2 locus on human chromosome 3: identification of a gene coding for four kringle domains with homology to hepatocyte growth factor.
PubMed ID: 1655021
DOI: 10.1021/bi00104a029
PubMed ID: 8393443
Title: Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins and locates the MSP gene on chromosome 3.
PubMed ID: 8393443
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1827141
Title: Macrophage stimulating protein: purification, partial amino acid sequence, and cellular activity.
PubMed ID: 1827141
PubMed ID: 9202013
Title: Macrophage stimulating protein (MSP) binds to its receptor via the MSP beta chain.
PubMed ID: 9202013
PubMed ID: 16335952
Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.
PubMed ID: 16335952
DOI: 10.1021/pr0502065
PubMed ID: 19079170
Title: Gene-centric association mapping of chromosome 3p implicates MST1 in IBD pathogenesis.
PubMed ID: 19079170
DOI: 10.1038/mi.2007.15
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 20228799
Title: Genome-wide association identifies multiple ulcerative colitis susceptibility loci.
PubMed ID: 20228799
DOI: 10.1038/ng.549
PubMed ID: 21875933
Title: Proteolytic activation of pro-macrophage-stimulating protein by hepsin.
PubMed ID: 21875933
PubMed ID: 22087277
Title: Protein characterization of a candidate mechanism SNP for Crohn's disease: the macrophage stimulating protein R689C substitution.
PubMed ID: 22087277
PubMed ID: 16279944
Title: Crystal structure of the beta-chain of human hepatocyte growth factor-like/macrophage stimulating protein.
PubMed ID: 16279944
Sequence Information:
- Length: 711
- Mass: 80320
- Checksum: 2E4B3C7D4AA9B566
- Sequence:
MGWLPLLLLL TQCLGVPGQR SPLNDFQVLR GTELQHLLHA VVPGPWQEDV ADAEECAGRC GPLMDCRAFH YNVSSHGCQL LPWTQHSPHT RLRRSGRCDL FQKKDYVRTC IMNNGVGYRG TMATTVGGLP CQAWSHKFPN DHKYTPTLRN GLEENFCRNP DGDPGGPWCY TTDPAVRFQS CGIKSCREAA CVWCNGEEYR GAVDRTESGR ECQRWDLQHP HQHPFEPGKF LDQGLDDNYC RNPDGSERPW CYTTDPQIER EFCDLPRCGS EAQPRQEATT VSCFRGKGEG YRGTANTTTA GVPCQRWDAQ IPHQHRFTPE KYACKDLREN FCRNPDGSEA PWCFTLRPGM RAAFCYQIRR CTDDVRPQDC YHGAGEQYRG TVSKTRKGVQ CQRWSAETPH KPQFTFTSEP HAQLEENFCR NPDGDSHGPW CYTMDPRTPF DYCALRRCAD DQPPSILDPP DQVQFEKCGK RVDRLDQRRS KLRVVGGHPG NSPWTVSLRN RQGQHFCGGS LVKEQWILTA RQCFSSCHMP LTGYEVWLGT LFQNPQHGEP SLQRVPVAKM VCGPSGSQLV LLKLERSVTL NQRVALICLP PEWYVVPPGT KCEIAGWGET KGTGNDTVLN VALLNVISNQ ECNIKHRGRV RESEMCTEGL LAPVGACEGD YGGPLACFTH NCWVLEGIII PNRVCARSRW PAVFTRVSVF VDWIHKVMRL G
Genular Protein ID: 792949311
Symbol: G3XAK1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 11181995
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
Sequence Information:
- Length: 725
- Mass: 81999
- Checksum: B222E0BDAC020D03
- Sequence:
MGLWWVTVQP PARRMGWLPL LLLLTQCLGV PGQRSPLNDF QVLRGTELQH LLHAVVPGPW QEDVADAEEC AGRCGPLMDC RAFHYNVSSH GCQLLPWTQH SPHTRLRRSG RCDLFQKKDY VRTCIMNNGV GYRGTMATTV GGLPCQAWSH KFPNDHKYTP TLRNGLEENF CRNPDGDPGG PWCYTTDPAV RFQSCGIKSC REAACVWCNG EEYRGAVDRT ESGRECQRWD LQHPHQHPFE PGKFLDQGLD DNYCRNPDGS ERPWCYTTDP QIEREFCDLP RCGSEAQPRQ EATTVSCFRG KGEGYRGTAN TTTAGVPCQR WDAQIPHQHR FTPEKYACKD LRENFCRNPD GSEAPWCFTL RPGMRAAFCY QIRRCTDDVR PQDCYHGAGE QYRGTVSKTR KGVQCQRWSA ETPHKPQFTF TSEPHAQLEE NFCRNPDGDS HGPWCYTMDP RTPFDYCALR RCADDQPPSI LDPPDQVQFE KCGKRVDRLD QRRSKLRVVG GHPGNSPWTV SLRNRQGQHF CGGSLVKEQW ILTARQCFSS CHMPLTGYEV WLGTLFQNPQ HGEPSLQRVP VAKMVCGPSG SQLVLLKLER SVTLNQRVAL ICLPPEWYVV PPGTKCEIAG WGETKGTGND TVLNVALLNV ISNQECNIKH RGRVRESEMC TEGLLAPVGA CEGDYGGPLA CFTHNCWVLE GIIIPNRVCA RSRWPAVFTR VSVFVDWIHK VMRLG
Genular Protein ID: 50203111
Symbol: Q53GN8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8125298
Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.
PubMed ID: 8125298
PubMed ID: 9373149
Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.
PubMed ID: 9373149
Sequence Information:
- Length: 711
- Mass: 80350
- Checksum: 2E4B3C7D4AAF9593
- Sequence:
MGWLPLLLLL TQCLGVPGQR SPLNDFQVLR GTELQHLLHA VVPGPWQEDV ADAEECAGRC GPLMDCRAFH YNVSSHGCQL LPWTQHSPHT RLRRSGRCDL FQKKDYVRTC IMNNGVGYRG TMATTVGGLP CQAWSHKFPN DHKYTPTLRN GLEENFCRNP DGDPGGPWCY TTDPAVRFQS CGIKSCREAA CVWCNGEEYR GTVDRTESGR ECQRWDLQHP HQHPFEPGKF LDQGLDDNYC RNPDGSERPW CYTTDPQIER EFCDLPRCGS EAQPRQEATT VSCFRGKGEG YRGTANTTTA GVPCQRWDAQ IPHQHRFTPE KYACKDLREN FCRNPDGSEA PWCFTLRPGM RAAFCYQIRR CTDDVRPQDC YHGAGEQYRG TVSKTRKGVQ CQRWSAETPH KPQFTFTSEP HAQLEENFCR NPDGDSHGPW CYTMDPRTPF DYCALRRCAD DQPPSILDPP DQVQFEKCGK RVDRLDQRRS KLRVVGGHPG NSPWTVSLRN RQGQHFCGGS LVKEQWILTA RQCFSSCHMP LTGYEVWLGT LFQNPQHGEP SLQRVPVAKM VCGPSGSQLV LLKLERSVTL NQRVALICLP PEWYVVPPGT KCEIAGWGET KGTGNDTVLN VALLNVISNQ ECNIKHRGRV RESEMCTEGL LAPVGACEGD YGGPLACFTH NCWVLEGIII PNRVCARSRW PAVFTRVSVF VDWIHKVMRL G
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.