Details for: MST1

Gene ID: 4485

Symbol: MST1

Ensembl ID: ENSG00000173531

Description: macrophage stimulating 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 27.1304
    Cell Significance Index: -4.2200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 24.6409
    Cell Significance Index: -6.2500
  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: 5.3413
    Cell Significance Index: 14.0900
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 4.3429
    Cell Significance Index: 34.6800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 4.2662
    Cell Significance Index: -5.2600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 3.0069
    Cell Significance Index: 572.2200
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 2.2259
    Cell Significance Index: 37.5000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 1.6105
    Cell Significance Index: -6.3600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.5980
    Cell Significance Index: 1442.8400
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: 1.5944
    Cell Significance Index: 6.0100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.5094
    Cell Significance Index: 43.4900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.4183
    Cell Significance Index: 38.0100
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 1.3909
    Cell Significance Index: 22.9200
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 1.2111
    Cell Significance Index: 5.8900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.1946
    Cell Significance Index: 71.7200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.1824
    Cell Significance Index: 128.6100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.1064
    Cell Significance Index: 219.5600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9978
    Cell Significance Index: 162.2900
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.8130
    Cell Significance Index: 12.0000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.6865
    Cell Significance Index: 47.4800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3621
    Cell Significance Index: 10.1200
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 0.3134
    Cell Significance Index: 1.8100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2967
    Cell Significance Index: 13.4500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.2683
    Cell Significance Index: 5.8800
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 0.2445
    Cell Significance Index: 1.2200
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.2311
    Cell Significance Index: 2.9600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.2225
    Cell Significance Index: 5.8500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2211
    Cell Significance Index: 7.7700
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 0.2173
    Cell Significance Index: 0.4900
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.2161
    Cell Significance Index: 1.7900
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: 0.2130
    Cell Significance Index: 2.3300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2025
    Cell Significance Index: 20.0300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.1840
    Cell Significance Index: 2.5100
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.1819
    Cell Significance Index: 1.1300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1744
    Cell Significance Index: 9.0600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.1165
    Cell Significance Index: 4.0500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1018
    Cell Significance Index: 13.0500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0995
    Cell Significance Index: 2.1200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0982
    Cell Significance Index: 17.7000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0968
    Cell Significance Index: 52.8800
  • Cell Name: columnar/cuboidal epithelial cell (CL0000075)
    Fold Change: 0.0966
    Cell Significance Index: 0.3700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0685
    Cell Significance Index: 9.4100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0545
    Cell Significance Index: 24.0800
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.0536
    Cell Significance Index: 0.8300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0524
    Cell Significance Index: 1.4300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0491
    Cell Significance Index: 9.8500
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.0485
    Cell Significance Index: 0.6800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0478
    Cell Significance Index: 2.9400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0464
    Cell Significance Index: 1.1600
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 0.0464
    Cell Significance Index: 0.3600
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.0405
    Cell Significance Index: 0.6500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0282
    Cell Significance Index: 10.1300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0234
    Cell Significance Index: 17.1800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0206
    Cell Significance Index: 2.5300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0189
    Cell Significance Index: 0.8900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0174
    Cell Significance Index: 2.9700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0137
    Cell Significance Index: 25.7400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0119
    Cell Significance Index: 18.3500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0116
    Cell Significance Index: 21.3500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.0082
    Cell Significance Index: 0.0900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.0059
    Cell Significance Index: 0.0900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0017
    Cell Significance Index: 0.2000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0002
    Cell Significance Index: -0.1200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0014
    Cell Significance Index: -1.8700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0021
    Cell Significance Index: -1.5900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0031
    Cell Significance Index: -0.4000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0064
    Cell Significance Index: -0.3000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0074
    Cell Significance Index: -5.5000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0091
    Cell Significance Index: -1.3300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0094
    Cell Significance Index: -0.9600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0096
    Cell Significance Index: -5.4400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0100
    Cell Significance Index: -4.5300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0107
    Cell Significance Index: -6.6800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0150
    Cell Significance Index: -4.3300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0167
    Cell Significance Index: -0.2800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0191
    Cell Significance Index: -1.3500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0199
    Cell Significance Index: -1.4800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0293
    Cell Significance Index: -1.8500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0316
    Cell Significance Index: -3.6800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0318
    Cell Significance Index: -6.7000
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0336
    Cell Significance Index: -0.9900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0355
    Cell Significance Index: -2.8100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0381
    Cell Significance Index: -1.2200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0420
    Cell Significance Index: -4.9500
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: -0.0426
    Cell Significance Index: -0.4200
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.0446
    Cell Significance Index: -1.0300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0453
    Cell Significance Index: -2.5400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0455
    Cell Significance Index: -3.5000
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: -0.0473
    Cell Significance Index: -0.6200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0512
    Cell Significance Index: -5.3300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0569
    Cell Significance Index: -1.1900
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.0600
    Cell Significance Index: -0.5100
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.0602
    Cell Significance Index: -0.4600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0682
    Cell Significance Index: -1.8200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0682
    Cell Significance Index: -3.5800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0712
    Cell Significance Index: -3.1500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0732
    Cell Significance Index: -4.9200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0786
    Cell Significance Index: -4.8200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0856
    Cell Significance Index: -5.5200
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.0935
    Cell Significance Index: -1.3400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Expression Pattern:** MST1 is widely expressed in various tissues, including the liver, kidney, reproductive organs, and immune cells. 2. **Signaling Pathways:** MST1 is involved in multiple signaling pathways, including receptor tyrosine kinase binding, regulation of camp-dependent protein kinase activity, and negative regulation of gluconeogenesis. 3. **Cell Type-Specific Expression:** MST1 is highly expressed in hepatocytes, nephron tubule epithelial cells, and immune cells such as macrophages and endothelial cells. 4. **Protein Interactions:** MST1 interacts with various proteins, including hepatocyte growth factor-like protein (HGFL), which is involved in cell proliferation and differentiation. **Pathways and Functions:** 1. **Receptor Tyrosine Kinase Binding:** MST1 binds to receptor tyrosine kinases, such as c-Met and Axl, to regulate cell signaling and proliferation. 2. **Regulation of Camp-Dependent Protein Kinase Activity:** MST1 regulates the activity of camp-dependent protein kinase (PKA), which is involved in various cellular processes, including cell proliferation and differentiation. 3. **Negative Regulation of Gluconeogenesis:** MST1 negatively regulates gluconeogenesis, a process that generates glucose from non-carbohydrate sources, which is essential for maintaining glucose homeostasis. 4. **Signaling by MST1:** MST1 signals through various pathways, including the PI3K/AKT and MAPK/ERK pathways, to regulate cell growth, differentiation, and survival. 5. **Regulation of Receptor Signaling Pathway via Jak-Stat:** MST1 regulates the receptor signaling pathway via the Jak-Stat pathway, which is involved in immune responses and inflammation. **Clinical Significance:** 1. **Cancer:** MST1 is overexpressed in various types of cancer, including breast, lung, and liver cancer, where it promotes tumor growth, metastasis, and resistance to therapy. 2. **Autoimmune Disorders:** MST1 is involved in the pathogenesis of autoimmune disorders, such as rheumatoid arthritis and lupus, where it regulates immune cell function and inflammation. 3. **Metabolic Disorders:** MST1 is involved in the regulation of glucose metabolism and insulin signaling, which is essential for maintaining glucose homeostasis and preventing metabolic disorders, such as type 2 diabetes. 4. **Neurological Disorders:** MST1 is involved in the regulation of neuronal function and survival, which is essential for maintaining neurological homeostasis and preventing disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, MST1 is a multifaceted gene that plays a crucial role in various cellular processes, including immune regulation, cell signaling, and tissue homeostasis. Its involvement in multiple signaling pathways and diseases underscores its complexity and versatility, making it an attractive target for therapeutic intervention in various diseases.

Genular Protein ID: 3032797769

Symbol: HGFL_HUMAN

Name: Hepatocyte growth factor-like protein

UniProtKB Accession Codes:

P26927 A6NLA3 A8MSX3 Q13350 Q14870 Q6GTN4

Database IDs:

AGR 1 AlphaFoldDB 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CDD 3 CPTAC 1 CPTC 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 EvolutionaryTrace 1 GO 8 Gene3D 3 GeneCards 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 InParanoid 1 IntAct 1 InterPro 12 KEGG 1 MEROPS 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 1 PIRSF 2 PRINTS 2 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1655021

Title: Characterization of the DNF15S2 locus on human chromosome 3: identification of a gene coding for four kringle domains with homology to hepatocyte growth factor.

PubMed ID: 1655021

DOI: 10.1021/bi00104a029

PubMed ID: 8393443

Title: Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins and locates the MSP gene on chromosome 3.

PubMed ID: 8393443

DOI: 10.1016/s0021-9258(18)82279-7

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1827141

Title: Macrophage stimulating protein: purification, partial amino acid sequence, and cellular activity.

PubMed ID: 1827141

DOI: 10.1084/jem.173.5.1227

PubMed ID: 9202013

Title: Macrophage stimulating protein (MSP) binds to its receptor via the MSP beta chain.

PubMed ID: 9202013

DOI: 10.1074/jbc.272.27.16999

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 19079170

Title: Gene-centric association mapping of chromosome 3p implicates MST1 in IBD pathogenesis.

PubMed ID: 19079170

DOI: 10.1038/mi.2007.15

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 20228799

Title: Genome-wide association identifies multiple ulcerative colitis susceptibility loci.

PubMed ID: 20228799

DOI: 10.1038/ng.549

PubMed ID: 21875933

Title: Proteolytic activation of pro-macrophage-stimulating protein by hepsin.

PubMed ID: 21875933

DOI: 10.1158/1541-7786.mcr-11-0004

PubMed ID: 22087277

Title: Protein characterization of a candidate mechanism SNP for Crohn's disease: the macrophage stimulating protein R689C substitution.

PubMed ID: 22087277

DOI: 10.1371/journal.pone.0027269

PubMed ID: 16279944

Title: Crystal structure of the beta-chain of human hepatocyte growth factor-like/macrophage stimulating protein.

PubMed ID: 16279944

DOI: 10.1111/j.1742-4658.2005.04968.x

Sequence Information:

  • Length: 711
  • Mass: 80320
  • Checksum: 2E4B3C7D4AA9B566
  • Sequence:
    • MGWLPLLLLL TQCLGVPGQR SPLNDFQVLR GTELQHLLHA VVPGPWQEDV ADAEECAGRC 
GPLMDCRAFH YNVSSHGCQL LPWTQHSPHT RLRRSGRCDL FQKKDYVRTC IMNNGVGYRG 
TMATTVGGLP CQAWSHKFPN DHKYTPTLRN GLEENFCRNP DGDPGGPWCY TTDPAVRFQS 
CGIKSCREAA CVWCNGEEYR GAVDRTESGR ECQRWDLQHP HQHPFEPGKF LDQGLDDNYC 
RNPDGSERPW CYTTDPQIER EFCDLPRCGS EAQPRQEATT VSCFRGKGEG YRGTANTTTA 
GVPCQRWDAQ IPHQHRFTPE KYACKDLREN FCRNPDGSEA PWCFTLRPGM RAAFCYQIRR 
CTDDVRPQDC YHGAGEQYRG TVSKTRKGVQ CQRWSAETPH KPQFTFTSEP HAQLEENFCR 
NPDGDSHGPW CYTMDPRTPF DYCALRRCAD DQPPSILDPP DQVQFEKCGK RVDRLDQRRS 
KLRVVGGHPG NSPWTVSLRN RQGQHFCGGS LVKEQWILTA RQCFSSCHMP LTGYEVWLGT 
LFQNPQHGEP SLQRVPVAKM VCGPSGSQLV LLKLERSVTL NQRVALICLP PEWYVVPPGT 
KCEIAGWGET KGTGNDTVLN VALLNVISNQ ECNIKHRGRV RESEMCTEGL LAPVGACEGD 
YGGPLACFTH NCWVLEGIII PNRVCARSRW PAVFTRVSVF VDWIHKVMRL G

Genular Protein ID: 792949311

Symbol: G3XAK1_HUMAN

Name: N/A

UniProtKB Accession Codes:

G3XAK1

Database IDs:

ARBA 2 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 GO 18 Gene3D 3 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 12 KEGG 1 MANE-Select 1 MEROPS 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 2 PRINTS 2 PROSITE 7 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 3 SUPFAM 3 TreeFam 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

Sequence Information:

  • Length: 725
  • Mass: 81999
  • Checksum: B222E0BDAC020D03
  • Sequence:
    • MGLWWVTVQP PARRMGWLPL LLLLTQCLGV PGQRSPLNDF QVLRGTELQH LLHAVVPGPW 
QEDVADAEEC AGRCGPLMDC RAFHYNVSSH GCQLLPWTQH SPHTRLRRSG RCDLFQKKDY 
VRTCIMNNGV GYRGTMATTV GGLPCQAWSH KFPNDHKYTP TLRNGLEENF CRNPDGDPGG 
PWCYTTDPAV RFQSCGIKSC REAACVWCNG EEYRGAVDRT ESGRECQRWD LQHPHQHPFE 
PGKFLDQGLD DNYCRNPDGS ERPWCYTTDP QIEREFCDLP RCGSEAQPRQ EATTVSCFRG 
KGEGYRGTAN TTTAGVPCQR WDAQIPHQHR FTPEKYACKD LRENFCRNPD GSEAPWCFTL 
RPGMRAAFCY QIRRCTDDVR PQDCYHGAGE QYRGTVSKTR KGVQCQRWSA ETPHKPQFTF 
TSEPHAQLEE NFCRNPDGDS HGPWCYTMDP RTPFDYCALR RCADDQPPSI LDPPDQVQFE 
KCGKRVDRLD QRRSKLRVVG GHPGNSPWTV SLRNRQGQHF CGGSLVKEQW ILTARQCFSS 
CHMPLTGYEV WLGTLFQNPQ HGEPSLQRVP VAKMVCGPSG SQLVLLKLER SVTLNQRVAL 
ICLPPEWYVV PPGTKCEIAG WGETKGTGND TVLNVALLNV ISNQECNIKH RGRVRESEMC 
TEGLLAPVGA CEGDYGGPLA CFTHNCWVLE GIIIPNRVCA RSRWPAVFTR VSVFVDWIHK 
VMRLG

Genular Protein ID: 50203111

Symbol: Q53GN8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q53GN8

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 3 InterPro 12 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 2 PRINTS 2 PROSITE 7 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 RefSeq 1 SAM 1 SMART 3 SUPFAM 3

Citations:

PubMed ID: 8125298

Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.

PubMed ID: 8125298

DOI: 10.1016/0378-1119(94)90802-8

PubMed ID: 9373149

Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.

PubMed ID: 9373149

DOI: 10.1016/S0378-1119(97)00411-3

Sequence Information:

  • Length: 711
  • Mass: 80350
  • Checksum: 2E4B3C7D4AAF9593
  • Sequence:
    • MGWLPLLLLL TQCLGVPGQR SPLNDFQVLR GTELQHLLHA VVPGPWQEDV ADAEECAGRC 
GPLMDCRAFH YNVSSHGCQL LPWTQHSPHT RLRRSGRCDL FQKKDYVRTC IMNNGVGYRG 
TMATTVGGLP CQAWSHKFPN DHKYTPTLRN GLEENFCRNP DGDPGGPWCY TTDPAVRFQS 
CGIKSCREAA CVWCNGEEYR GTVDRTESGR ECQRWDLQHP HQHPFEPGKF LDQGLDDNYC 
RNPDGSERPW CYTTDPQIER EFCDLPRCGS EAQPRQEATT VSCFRGKGEG YRGTANTTTA 
GVPCQRWDAQ IPHQHRFTPE KYACKDLREN FCRNPDGSEA PWCFTLRPGM RAAFCYQIRR 
CTDDVRPQDC YHGAGEQYRG TVSKTRKGVQ CQRWSAETPH KPQFTFTSEP HAQLEENFCR 
NPDGDSHGPW CYTMDPRTPF DYCALRRCAD DQPPSILDPP DQVQFEKCGK RVDRLDQRRS 
KLRVVGGHPG NSPWTVSLRN RQGQHFCGGS LVKEQWILTA RQCFSSCHMP LTGYEVWLGT 
LFQNPQHGEP SLQRVPVAKM VCGPSGSQLV LLKLERSVTL NQRVALICLP PEWYVVPPGT 
KCEIAGWGET KGTGNDTVLN VALLNVISNQ ECNIKHRGRV RESEMCTEGL LAPVGACEGD 
YGGPLACFTH NCWVLEGIII PNRVCARSRW PAVFTRVSVF VDWIHKVMRL G

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.