Details for: TRIM37

Gene ID: 4591

Symbol: TRIM37

Ensembl ID: ENSG00000108395

Description: tripartite motif containing 37

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 216.8501
    Cell Significance Index: -33.7300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 132.6863
    Cell Significance Index: -33.6600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 72.9260
    Cell Significance Index: -34.4300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 65.8204
    Cell Significance Index: -26.7400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 28.1032
    Cell Significance Index: -34.6500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 27.9342
    Cell Significance Index: -26.6700
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 11.9416
    Cell Significance Index: -31.9900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 10.2850
    Cell Significance Index: -31.5900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.8595
    Cell Significance Index: -34.9600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 6.7852
    Cell Significance Index: -14.8500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 4.4747
    Cell Significance Index: 851.5700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.0324
    Cell Significance Index: 407.7000
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 1.5625
    Cell Significance Index: 19.3800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.4456
    Cell Significance Index: 518.5000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 1.2161
    Cell Significance Index: 34.7100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.1601
    Cell Significance Index: 188.6900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.0516
    Cell Significance Index: 39.8200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.0071
    Cell Significance Index: 696.5500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.9911
    Cell Significance Index: 43.8400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.9775
    Cell Significance Index: 65.7300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.8818
    Cell Significance Index: 796.2400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.8417
    Cell Significance Index: 167.0400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.6981
    Cell Significance Index: 44.0000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.6345
    Cell Significance Index: 69.0200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5881
    Cell Significance Index: 35.3100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.5394
    Cell Significance Index: 30.2700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4838
    Cell Significance Index: 47.8600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.4521
    Cell Significance Index: 34.6900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.4066
    Cell Significance Index: 24.9900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.3892
    Cell Significance Index: 4.6400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3607
    Cell Significance Index: 10.0800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.3409
    Cell Significance Index: 7.4700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3394
    Cell Significance Index: 61.1800
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.2982
    Cell Significance Index: 6.3800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2493
    Cell Significance Index: 5.4000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.2403
    Cell Significance Index: 28.0000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2258
    Cell Significance Index: 27.7600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2140
    Cell Significance Index: 116.8600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.1881
    Cell Significance Index: 4.5100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1836
    Cell Significance Index: 4.5900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1750
    Cell Significance Index: 7.9300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1623
    Cell Significance Index: 4.6800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1577
    Cell Significance Index: 8.2800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1260
    Cell Significance Index: 2.1600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1202
    Cell Significance Index: 226.3600
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 0.1072
    Cell Significance Index: 1.4300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0797
    Cell Significance Index: 35.2200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0729
    Cell Significance Index: 46.2900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0607
    Cell Significance Index: 82.4900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0549
    Cell Significance Index: 84.4900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0424
    Cell Significance Index: 78.1200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0174
    Cell Significance Index: 0.6100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0138
    Cell Significance Index: 1.8900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0132
    Cell Significance Index: 5.9900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: 0.0032
    Cell Significance Index: 2.3900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0071
    Cell Significance Index: -0.1900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0137
    Cell Significance Index: -8.5400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0273
    Cell Significance Index: -20.0100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0291
    Cell Significance Index: -1.5100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0337
    Cell Significance Index: -2.3300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0386
    Cell Significance Index: -29.2200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0409
    Cell Significance Index: -23.0800
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.0417
    Cell Significance Index: -0.5200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0490
    Cell Significance Index: -5.7800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0587
    Cell Significance Index: -10.0200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0680
    Cell Significance Index: -3.1700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0925
    Cell Significance Index: -11.8600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0935
    Cell Significance Index: -19.7000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0977
    Cell Significance Index: -28.1100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1110
    Cell Significance Index: -16.1400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1413
    Cell Significance Index: -3.0100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1582
    Cell Significance Index: -16.1600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1750
    Cell Significance Index: -22.6100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1807
    Cell Significance Index: -20.7000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1873
    Cell Significance Index: -6.0000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2035
    Cell Significance Index: -4.3200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.2260
    Cell Significance Index: -4.4100
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.2545
    Cell Significance Index: -3.3000
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.2559
    Cell Significance Index: -3.2300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2629
    Cell Significance Index: -19.5900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2645
    Cell Significance Index: -12.4300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2676
    Cell Significance Index: -27.8700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2836
    Cell Significance Index: -7.2900
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2881
    Cell Significance Index: -32.8900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2884
    Cell Significance Index: -15.0200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2885
    Cell Significance Index: -18.6200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.2989
    Cell Significance Index: -5.9100
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.3198
    Cell Significance Index: -6.4200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.3300
    Cell Significance Index: -23.3400
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.3429
    Cell Significance Index: -4.9100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3566
    Cell Significance Index: -28.2400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3802
    Cell Significance Index: -12.1100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.3864
    Cell Significance Index: -10.3600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4154
    Cell Significance Index: -13.6000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4260
    Cell Significance Index: -26.1200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5494
    Cell Significance Index: -19.0900
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.5499
    Cell Significance Index: -11.8800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5743
    Cell Significance Index: -15.1000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.6230
    Cell Significance Index: -8.5000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.6257
    Cell Significance Index: -21.9200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** TRIM37 is characterized by its ability to interact with multiple protein partners, modulate protein stability, and regulate gene expression through various post-translational modifications. Its unique tripartite motif enables it to recognize and bind to specific protein sequences, facilitating its interactions with other proteins. TRIM37 also exhibits a high degree of specificity, with its binding affinity and activity varying across different cellular contexts. **Pathways and Functions:** TRIM37 is involved in multiple signaling pathways, including: 1. **Adaptive Immune System:** TRIM37 regulates T-cell receptor signaling, modulating the activation and proliferation of T-cells. Its interaction with ubiquitin ligases and E3 enzymes influences the ubiquitination and proteasomal degradation of key immune regulatory proteins. 2. **Aggresome Assembly:** TRIM37 contributes to the formation of aggresomes, which are protein aggregates that regulate protein homeostasis and cellular stress responses. 3. **Antigen Processing and Presentation:** TRIM37 interacts with MHC class I molecules, influencing the presentation of antigens to CD8+ T-cells. 4. **Chromatin Regulation:** TRIM37 binds to histone H2A, regulating its ubiquitination and modifying chromatin structure, which in turn affects gene expression. 5. **Protein Homeostasis:** TRIM37 modulates protein stability through its ubiquitination and proteasomal degradation activities, maintaining protein homeostasis and preventing protein misfolding. **Clinical Significance:** TRIM37's dysregulation has been implicated in various diseases, including: 1. **Autoimmune Disorders:** Alterations in TRIM37 function have been linked to autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. 2. **Cancer:** TRIM37's involvement in protein homeostasis and chromatin regulation makes it a potential target for cancer therapy. 3. **Neurological Disorders:** TRIM37's role in regulating neuronal function and synaptic plasticity has implications for the treatment of neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, TRIM37 is a multifaceted protein that plays a critical role in regulating immune responses, cellular homeostasis, and chromatin structure. Its dysregulation has significant implications for various diseases, highlighting the need for further research into the molecular mechanisms underlying TRIM37's functions and its potential therapeutic applications.

Genular Protein ID: 1527636217

Symbol: TRI37_HUMAN

Name: N/A

UniProtKB Accession Codes:

O94972 A8K0V9 A8K8U4 A8MZ79 B4DGZ3 F8WEE6 Q7Z3E6 Q8IYF7 Q8WYF7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 3 CTD 1 ChEBI 4 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 EC 1 EMBL 13 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 27 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 1 RefSeq 4 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 2 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10048485

Title: Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10048485

DOI: 10.1093/dnares/5.6.355

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10888877

Title: Gene encoding a new RING-B-box-coiled-coil protein is mutated in mulibrey nanism.

PubMed ID: 10888877

DOI: 10.1038/77053

PubMed ID: 11938494

Title: The TRIM37 gene encodes a peroxisomal RING-B-box-coiled-coil protein: classification of mulibrey nanism as a new peroxisomal disorder.

PubMed ID: 11938494

DOI: 10.1086/340256

PubMed ID: 12754710

Title: A novel splice site mutation in the TRIM37 gene causes mulibrey nanism in a Turkish family with phenotypic heterogeneity.

PubMed ID: 12754710

DOI: 10.1002/humu.10220

PubMed ID: 15885686

Title: TRIM37 defective in mulibrey nanism is a novel RING finger ubiquitin E3 ligase.

PubMed ID: 15885686

DOI: 10.1016/j.yexcr.2005.04.001

PubMed ID: 16310976

Title: Characterisation of the mulibrey nanism-associated TRIM37 gene: transcription initiation, promoter region and alternative splicing.

PubMed ID: 16310976

DOI: 10.1016/j.gene.2005.08.008

PubMed ID: 17551331

Title: A novel mutation in TRIM37 is associated with mulibrey nanism in a Turkish boy.

PubMed ID: 17551331

DOI: 10.1097/mcd.0b013e3280f6d00b

PubMed ID: 21865362

Title: Testicular failure and male infertility in the monogenic Mulibrey nanism disorder.

PubMed ID: 21865362

DOI: 10.1210/jc.2011-1493

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23769972

Title: Discovering regulators of centriole biogenesis through siRNA-based functional genomics in human cells.

PubMed ID: 23769972

DOI: 10.1016/j.devcel.2013.05.016

PubMed ID: 23385855

Title: Refractory congestive heart failure following delayed pericardectomy in a 12-year-old child with Mulibrey nanism due to a novel mutation in TRIM37.

PubMed ID: 23385855

DOI: 10.1007/s00431-013-1962-2

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24317724

Title: Anti-HIV-1 activity of Trim 37.

PubMed ID: 24317724

DOI: 10.1099/vir.0.057653-0

PubMed ID: 25470042

Title: TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein.

PubMed ID: 25470042

DOI: 10.1038/nature13955

PubMed ID: 28724525

Title: TRIM37, a novel E3 ligase for PEX5-mediated peroxisomal matrix protein import.

PubMed ID: 28724525

DOI: 10.1083/jcb.201611170

PubMed ID: 15108285

Title: Novel mutations in the TRIM37 gene in Mulibrey Nanism.

PubMed ID: 15108285

DOI: 10.1002/humu.9233

PubMed ID: 17100991

Title: Wilms' tumor and novel TRIM37 mutations in an Australian patient with mulibrey nanism.

PubMed ID: 17100991

DOI: 10.1111/j.1399-0004.2006.00700.x

PubMed ID: 26697951

Title: FTO variant associated with malformation syndrome.

PubMed ID: 26697951

DOI: 10.1002/ajmg.a.37515

Sequence Information:

  • Length: 964
  • Mass: 107906
  • Checksum: C0F08D5A5DC3B5AC
  • Sequence:
    • MDEQSVESIA EVFRCFICME KLRDARLCPH CSKLCCFSCI RRWLTEQRAQ CPHCRAPLQL 
RELVNCRWAE EVTQQLDTLQ LCSLTKHEEN EKDKCENHHE KLSVFCWTCK KCICHQCALW 
GGMHGGHTFK PLAEIYEQHV TKVNEEVAKL RRRLMELISL VQEVERNVEA VRNAKDERVR 
EIRNAVEMMI ARLDTQLKNK LITLMGQKTS LTQETELLES LLQEVEHQLR SCSKSELISK 
SSEILMMFQQ VHRKPMASFV TTPVPPDFTS ELVPSYDSAT FVLENFSTLR QRADPVYSPP 
LQVSGLCWRL KVYPDGNGVV RGYYLSVFLE LSAGLPETSK YEYRVEMVHQ SCNDPTKNII 
REFASDFEVG ECWGYNRFFR LDLLANEGYL NPQNDTVILR FQVRSPTFFQ KSRDQHWYIT 
QLEAAQTSYI QQINNLKERL TIELSRTQKS RDLSPPDNHL SPQNDDALET RAKKSACSDM 
LLEGGPTTAS VREAKEDEED EEKIQNEDYH HELSDGDLDL DLVYEDEVNQ LDGSSSSASS 
TATSNTEEND IDEETMSGEN DVEYNNMELE EGELMEDAAA AGPAGSSHGY VGSSSRISRR 
THLCSAATSS LLDIDPLILI HLLDLKDRSS IENLWGLQPR PPASLLQPTA SYSRKDKDQR 
KQQAMWRVPS DLKMLKRLKT QMAEVRCMKT DVKNTLSEIK SSSAASGDMQ TSLFSADQAA 
LAACGTENSG RLQDLGMELL AKSSVANCYI RNSTNKKSNS PKPARSSVAG SLSLRRAVDP 
GENSRSKGDC QTLSEGSPGS SQSGSRHSSP RALIHGSIGD ILPKTEDRQC KALDSDAVVV 
AVFSGLPAVE KRRKMVTLGA NAKGGHLEGL QMTDLENNSE TGELQPVLPE GASAAPEEGM 
SSDSDIECDT ENEEQEEHTS VGGFHDSFMV MTQPPDEDTH SSFPDGEQIG PEDLSFNTDE 
NSGR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.