Details for: MYO9B

Gene ID: 4650

Symbol: MYO9B

Ensembl ID: ENSG00000099331

Description: myosin IXB

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 345.2372
    Cell Significance Index: -53.7000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 204.6180
    Cell Significance Index: -51.9000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 116.4051
    Cell Significance Index: -54.9600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 109.9796
    Cell Significance Index: -44.6800
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 99.1280
    Cell Significance Index: -50.9900
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 82.2626
    Cell Significance Index: -55.2000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 47.3216
    Cell Significance Index: -45.1800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 44.1378
    Cell Significance Index: -54.4200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 17.4085
    Cell Significance Index: -46.6400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 16.2159
    Cell Significance Index: -35.4900
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 15.8492
    Cell Significance Index: -48.6800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 13.9000
    Cell Significance Index: -54.8500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 2.0732
    Cell Significance Index: 116.3400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.4915
    Cell Significance Index: 299.1900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.3469
    Cell Significance Index: 267.2900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.2351
    Cell Significance Index: 355.3700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.1660
    Cell Significance Index: 21.5500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.9989
    Cell Significance Index: 76.6600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9834
    Cell Significance Index: 887.9100
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.9692
    Cell Significance Index: 15.5500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.6878
    Cell Significance Index: 246.7100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6214
    Cell Significance Index: 101.0700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5981
    Cell Significance Index: 41.3600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.5240
    Cell Significance Index: 362.4500
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.5218
    Cell Significance Index: 6.2200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.5074
    Cell Significance Index: 14.1800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.5010
    Cell Significance Index: 32.3300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3728
    Cell Significance Index: 40.5500
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.3653
    Cell Significance Index: 7.1300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3585
    Cell Significance Index: 22.0400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3487
    Cell Significance Index: 42.8800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.3415
    Cell Significance Index: 40.2700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3283
    Cell Significance Index: 59.1900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3189
    Cell Significance Index: 60.6800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2450
    Cell Significance Index: 7.0600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2367
    Cell Significance Index: 10.7300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.2074
    Cell Significance Index: 5.9500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.2028
    Cell Significance Index: 5.4400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1454
    Cell Significance Index: 197.6400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1392
    Cell Significance Index: 76.0400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0927
    Cell Significance Index: 142.6600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0868
    Cell Significance Index: 11.9200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0750
    Cell Significance Index: 4.7300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0678
    Cell Significance Index: 6.7100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0651
    Cell Significance Index: 3.3900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0585
    Cell Significance Index: 110.2400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0466
    Cell Significance Index: 1.0100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0409
    Cell Significance Index: 25.9700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0216
    Cell Significance Index: 1.4500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0210
    Cell Significance Index: 38.7500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0087
    Cell Significance Index: 0.4100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0063
    Cell Significance Index: 2.7700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0007
    Cell Significance Index: -0.0200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0207
    Cell Significance Index: -9.3700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0208
    Cell Significance Index: -0.7300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0598
    Cell Significance Index: -43.8400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0655
    Cell Significance Index: -49.6000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0743
    Cell Significance Index: -9.6100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0784
    Cell Significance Index: -11.4000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0810
    Cell Significance Index: -59.9900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0957
    Cell Significance Index: -1.6400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1015
    Cell Significance Index: -63.3600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1054
    Cell Significance Index: -59.4200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1489
    Cell Significance Index: -15.2100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1894
    Cell Significance Index: -22.0700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.2293
    Cell Significance Index: -39.1500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.2333
    Cell Significance Index: -29.9100
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.2503
    Cell Significance Index: -3.6000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2822
    Cell Significance Index: -14.6600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3028
    Cell Significance Index: -63.7700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3435
    Cell Significance Index: -25.6000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3775
    Cell Significance Index: -5.1500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.4087
    Cell Significance Index: -46.8200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4499
    Cell Significance Index: -46.8500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.4774
    Cell Significance Index: -22.2600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.5188
    Cell Significance Index: -14.1200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.5786
    Cell Significance Index: -40.9200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6158
    Cell Significance Index: -48.7700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6283
    Cell Significance Index: -38.5200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.6334
    Cell Significance Index: -15.1900
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.6371
    Cell Significance Index: -8.9300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.6505
    Cell Significance Index: -16.2600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.6551
    Cell Significance Index: -13.5900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.8116
    Cell Significance Index: -35.9000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.8848
    Cell Significance Index: -19.3800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.9305
    Cell Significance Index: -48.8600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.9311
    Cell Significance Index: -19.8300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.9701
    Cell Significance Index: -31.0700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -1.0042
    Cell Significance Index: -38.0300
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -1.1020
    Cell Significance Index: -11.8200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.1340
    Cell Significance Index: -29.1500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.1754
    Cell Significance Index: -41.1800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -1.1807
    Cell Significance Index: -25.0600
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -1.1815
    Cell Significance Index: -10.8800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -1.1917
    Cell Significance Index: -35.0000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.1956
    Cell Significance Index: -38.0800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.2104
    Cell Significance Index: -39.6300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.2150
    Cell Significance Index: -42.2200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -1.2178
    Cell Significance Index: -31.1100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.2447
    Cell Significance Index: -33.3000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** MYO9B is an unconventional myosin, belonging to the myosin IX family. It consists of two heavy chains and six light chains, with a molecular weight of approximately 140 kDa. The protein has a characteristic tail domain, which interacts with calmodulin and other signaling proteins. MYO9B exhibits a high degree of specificity in its interactions with actin filaments, binding to actin at the plus end and generating a force to drive actin filament-based movement. **Pathways and Functions** MYO9B is involved in various signaling pathways, including: 1. **Actin dynamics regulation**: MYO9B regulates actin filament dynamics, influencing cell movement, shape, and morphology. 2. **Phagocytosis**: MYO9B is essential for phagocytic cup formation and movement, facilitating the engulfment and internalization of pathogens and foreign particles. 3. **Immune system regulation**: MYO9B is expressed in immune cells, including macrophages and microglia, and regulates immune responses to infections and inflammation. 4. **Nervous system development**: MYO9B is involved in axon guidance and neuronal development, influencing the formation of neural connections and synapses. 5. **Innate immune response**: MYO9B regulates the innate immune response to pathogens, influencing the activation and function of immune cells. **Clinical Significance** Abnormalities in MYO9B have been implicated in various diseases, including: 1. **Infectious diseases**: MYO9B dysfunction has been linked to impaired phagocytosis, leading to increased susceptibility to infections. 2. **Neurodegenerative disorders**: MYO9B mutations have been associated with neurodegenerative diseases, such as Leishmania infection and neurodegenerative disorders. 3. **Cancer**: MYO9B overexpression has been observed in certain types of cancer, suggesting a role in tumor progression and metastasis. 4. **Immune system disorders**: MYO9B dysfunction has been implicated in autoimmune diseases, such as rheumatoid arthritis and lupus. In conclusion, MYO9B is a critical regulator of actin dynamics, phagocytosis, and immune system function. Its unique structure and function enable it to influence various cellular processes, and its dysfunction has been implicated in various diseases. Further research is necessary to fully understand the role of MYO9B in human health and disease.

Genular Protein ID: 714980276

Symbol: MYO9B_HUMAN

Name: Unconventional myosin-IXb

UniProtKB Accession Codes:

Q13459 O75314 Q9NUJ2 Q9UHN0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 4 CPTAC 2 CTD 1 ChEBI 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 6 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 28 Gene3D 8 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 14 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PRINTS 1 PRO 1 PROSITE 6 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 9 RefSeq 1 SIGNOR 1 SMART 5 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 2 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8907710

Title: Human myosin-IXb, an unconventional myosin with a chimerin-like rho/rac GTPase-activating protein domain in its tail.

PubMed ID: 8907710

DOI: 10.1242/jcs.109.3.653

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 10580159

Title: Cloning of the murine unconventional myosin gene Myo9b and identification of alternative splicing.

PubMed ID: 10580159

DOI: 10.1016/s0378-1119(99)00459-x

PubMed ID: 9490638

Title: Human myosin-IXb is a mechanochemically active motor and a GAP for rho.

PubMed ID: 9490638

DOI: 10.1242/jcs.111.7.941

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16964243

Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

PubMed ID: 16964243

DOI: 10.1038/nbt1240

PubMed ID: 19367720

Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.

PubMed ID: 19367720

DOI: 10.1021/pr800500r

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26529257

Title: Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression.

PubMed ID: 26529257

DOI: 10.1172/jci81673

Sequence Information:

  • Length: 2157
  • Mass: 243401
  • Checksum: A3E72CAB759CD5FD
  • Sequence:
    • MSVKEAGSSG RREQAAYHLH IYPQLSTTES QASCRVTATK DSTTSDVIKD AIASLRLDGT 
KCYVLVEVKE SGGEEWVLDA NDSPVHRVLL WPRRAQDEHP QEDGYYFLLQ ERNADGTIKY 
VHMQLVAQAT ATRRLVERGL LPRQQADFDD LCNLPELTEG NLLKNLKHRF LQQKIYTYAG 
SILVAINPFK FLPIYNPKYV KMYENQQLGK LEPHVFALAD VAYYTMLRKR VNQCIVISGE 
SGSGKTQSTN FLIHCLTALS QKGYASGVER TILGAGPVLE AFGNAKTAHN NNSSRFGKFI 
QVSYLESGIV RGAVVEKYLL EKSRLVSQEK DERNYHVFYY LLLGVSEEER QEFQLKQPED 
YFYLNQHNLK IEDGEDLKHD FERLKQAMEM VGFLPATKKQ IFAVLSAILY LGNVTYKKRA 
TGREEGLEVG PPEVLDTLSQ LLKVKREILV EVLTKRKTVT VNDKLILPYS LSEAITARDS 
MAKSLYSALF DWIVLRINHA LLNKKDVEEA VSCLSIGVLD IFGFEDFERN SFEQFCINYA 
NEQLQYYFNQ HIFKLEQEEY QGEGITWHNI GYTDNVGCIH LISKKPTGLF YLLDEESNFP 
HATSQTLLAK FKQQHEDNKY FLGTPVMEPA FIIQHFAGKV KYQIKDFREK NMDYMRPDIV 
ALLRGSDSSY VRELIGMDPV AVFRWAVLRA AIRAMAVLRE AGRLRAERAE KAAGMSSPGA 
QSHPEELPRG ASTPSEKLYR DLHNQMIKSI KGLPWQGEDP RSLLQSLSRL QKPRAFILKS 
KGIKQKQIIP KNLLDSKSLK LIISMTLHDR TTKSLLHLHK KKKPPSISAQ FQTSLNKLLE 
ALGKAEPFFI RCIRSNAEKK ELCFDDELVL QQLRYTGMLE TVRIRRSGYS AKYTFQDFTE 
QFQVLLPKDA QPCREVISTL LEKMKIDKRN YQIGKTKVFL KETERQALQE TLHREVVRKI 
LLLQSWFRMV LERRHFLQMK RAAVTIQACW RSYRVRRALE RTQAAVYLQA SWRGYWQRKL 
YRHQKQSIIR LQSLCRGHLQ RKSFSQMISE KQKAEEKERE ALEAARAGAE EGGQGQAAGG 
QQVAEQGPEP AEDGGHLASE PEVQPSDRSP LEHSSPEKEA PSPEKTLPPQ KTVAAESHEK 
VPSSREKRES RRQRGLEHVK FQNKHIQSCK EESALREPSR RVTQEQGVSL LEDKKESRED 
ETLLVVETEA ENTSQKQPTE QPQAMAVGKV SEETEKTLPS GSPRPGQLER PTSLALDSRV 
SPPAPGSAPE TPEDKSKPCG SPRVQEKPDS PGGSTQIQRY LDAERLASAV ELWRGKKLVA 
AASPSAMLSQ SLDLSDRHRA TGAALTPTEE RRTSFSTSDV SKLLPSLAKA QPAAETTDGE 
RSAKKPAVQK KKPGDASSLP DAGLSPGSQV DSKSTFKRLF LHKTKDKKYS LEGAEELENA 
VSGHVVLEAT TMKKGLEAPS GQQHRHAAGE KRTKEPGGKG KKNRNVKIGK ITVSEKWRES 
VFRQITNANE LKYLDEFLLN KINDLRSQKT PIESLFIEAT EKFRSNIKTM YSVPNGKIHV 
GYKDLMENYQ IVVSNLATER GQKDTNLVLN LFQSLLDEFT RGYTKNDFEP VKQSKAQKKK 
RKQERAVQEH NGHVFASYQV SIPQSCEQCL SYIWLMDKAL LCSVCKMTCH KKCVHKIQSH 
CSYTYGRKGE PGVEPGHFGV CVDSLTSDKA SVPIVLEKLL EHVEMHGLYT EGLYRKSGAA 
NRTRELRQAL QTDPAAVKLE NFPIHAITGV LKQWLRELPE PLMTFAQYGD FLRAVELPEK 
QEQLAAIYAV LEHLPEANHN SLERLIFHLV KVALLEDVNR MSPGALAIIF APCLLRCPDN 
SDPLTSMKDV LKITTCVEML IKEQMRKYKV KMEEISQLEA AESIAFRRLS LLRQNAPWPL 
KLGFSSPYEG VLNKSPKTRD IQEEELEVLL EEEAAGGDED REKEILIERI QSIKEEKEDI 
TYRLPELDPR GSDEENLDSE TSASTESLLE ERAGRGASEG PPAPALPCPG APTPSPLPTV 
AAPPRRRPSS FVTVRVKTPR RTPIMPTANI KLPPGLPSHL PRWAPGAREA AAPVRRREPP 
ARRPDQIHSV YITPGADLPV QGALEPLEED GQPPGAKRRY SDPPTYCLPP ASGQTNG

Genular Protein ID: 85090103

Symbol: Q8WVD2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8WVD2

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 7 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 2 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 501
  • Mass: 55557
  • Checksum: 85D19A22863846F2
  • Sequence:
    • DKALLCSVCK MTCHKKCVHK IQSHCSYTYG RKGEPGVEPG HFGVCVDSLT SDKASVPIVL 
EKLLEHVEMH GLYTEGLYRK SGAANRTREL RQALQTDPAA VKLENFPIHA ITGVLKQWLR 
ELPEPLMTFA QYGDFLRAVE LPEKQEQLAA IYAVLEHLPE ANHNSLERLI FHLVKVALLE 
DVNRMSPGAL AIIFAPCLLR CPDNSDPLTS MKDVLKITTC VEMLIKEQMR KYKVKMEEIS 
QLEAAESIAF RRLSLLRQNA PWPLKLGFSS PYEGVLNKSP KTRDIQEEEL EVLLEEEAAG 
GDEDREKEIL IERIQSIKEE KEDITYRLPE LDPRGSDEEN LDSETSASTE SLLEERAGRG 
ASEGPPAPAL PCPGAPTPSP LPTVAAPPRR RPSSFVTVRV KTPRRTPIMP TANIKLPPGL 
PSHLPRWAPG AREAAAPVRR REPPARRPDQ IHSVYITPGA DLPVQGALEP LEEDGQPPGA 
KRRYSDPPTY CLPPASGQTN G

Genular Protein ID: 2204136108

Symbol: Q4LE74_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q4LE74

Database IDs:

ARBA 8 BioGRID-ORCS 1 CDD 4 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 9 Gene3D 8 InterPro 14 NCBI Taxonomy 1 PANTHER 2 PRINTS 1 PROSITE 10 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 RefSeq 1 SAM 1 SMART 5 SUPFAM 4

Sequence Information:

  • Length: 2028
  • Mass: 229714
  • Checksum: 36290F3E28DD0469
  • Sequence:
    • SQAAGRMSVK EAGSSGRREQ AAYHLHIYPQ LSTTESQASC RVTATKDSTT SDVIKDAIAS 
LRLDGTKCYV LVEVKESGGE EWVLDANDSP VHRVLLWPRR AQDEHPQEDG YYFLLQERNA 
DGTIKYVHMQ LVAQATATRR LVERGLLPRQ QADFDDLCNL PELTEGNLLK NLKHRFLQQK 
IYTYAGSILV AINPFKFLPI YNPKYVKMYE NQQLGKLEPH VFALADVAYY TMLRKRVNQC 
IVISGESGSG KTQSTNFLIH CLTALSQKGY ASGVERTILG AGPVLEAFGN AKTAHNNNSS 
RFGKFIQVSY LESGIVRGAV VEKYLLEKSR LVSQEKDERN YHVFYYLLLG VSEEERQEFQ 
LKQPEDYFYL NQHNLKIEDG EDLKHDFERL KQAMEMVGFL PATKKQIFAV LSAILYLGNV 
TYKKRATGRE EGLEVGPPEV LDTLSQLLKV KREILVEVLT KRKTVTVNDK LILPYSLSEA 
ITARDSMAKS LYSALFDWIV LRINHALLNK KDVEEAVSCL SIGVLDIFGF EDFERNSFEQ 
FCINYANEQL QYYFNQHIFK LEQEEYQGEG ITWHNIGYTD NVGCIHLISK KPTGLFYLLD 
EESNFPHATS QTLLAKFKQQ HEDNKYFLGT PVMEPAFIIQ HFAGKVKYQI KDFREKNMDY 
MRPDIVALLR GSDSSYVREL IGMDPVAVFR WAVLRAAIRA MAVLREAGRL RAERAEKAAG 
MSSPGAQSHP EELPRGASTP SEKLYRDLHN QMIKSIKGLP WQGEDPRSLL QSLSRLQKPR 
AFILKSKGIK QKQIIPKNLL DSKSLKLIIS MTLHDRTTKS LLHLHKKKKP PSISAQFQTS 
LNKLLEALGK AEPFFIRCIR SNAEKKELCF DDELVLQQLR YTGMLETVRI RRSGYSAKYT 
FQDFTEQFQV LLPKDAQPCR EVISTLLEKM KIDKRNYQIG KTKVFLKETE RQALQETLHR 
EVVRKILLLQ SWFRMVLERR HFLQMKRAAV TIQACWRSYR VRRALERTQA AVYLQASWRG 
YWQRKLYRHQ KQSIIRLQSL CRGHLQRKSF SQMISEKQKA EEKEREALEA ARAGAEEGGQ 
GQAAGGQQVA EQGPEPAEDG GHLASEPEVQ PSDRSPLEHS SPEKEAPSPE KTLPPQKTVA 
AESHEKVPSS REKRESRRQR GLEHVKFQNK HIQSCKEESA LREPSRRVTQ EQGVSLLEDK 
KESREDETLL VVETEAENTS QKQPTEQPQA MAVGKVSEET EKTLPSGSPR PGQLERPTSL 
ALDSRVSPPA PGSAPETPED KSKPCGSPRV QEKPDSPGGS TQIQRYLDAE RLASAVELWR 
GKKLVAAASP SAMLSQSLDL SDRHRATGAA LTPTEERRTS FSTSDVSKLL PSLAKAQPAA 
ETTDGERSAK KPAVQKKKPG DASSLPDAGL SPGSQVDSKS TFKRLFLHKT KDKKYSLEGA 
EELENAVSGH VVLEATTMKK GLEAPSGQQH RHAAGEKRTK EPGGKGKKNR NVKIGKITVS 
EKWRESVFRQ ITNANELKYL DEFLLNKIND LRSQKTPIES LFIEATEKFR SNIKTMYSVP 
NGKIHVGYKD LMENYQIVVS NLATERGQKD TNLVLNLFQS LLDEFTRGYT KNDFEPVKQS 
KAQKKKRKQE RAVQEHNGHV FASYQVSIPQ SCEQCLSYIW LMDKALLCSV CKMTCHKKCV 
HKIQSHCSYT YGRKGEPGVE PGHFGVCVDS LTSDKASVPI VLEKLLEHVE MHGLYTEGLY 
RKSGAANRTR ELRQALQTDP AAVKLENFPI HAITGVLKQW LRELPEPLMT FAQYGDFLRA 
VELPEKQEQL AAIYAVLEHL PEANHNSLER LIFHLVKVAL LEDVNRMSPG ALAIIFAPCL 
LRCPDNSDPL TSMKDVLKIT TCVEMLIKEQ MRKYKVKMEE ISQLEAAESI AFRRLSLLRQ 
NAPWPLKLGF SSPYEGVLNK SPKTRDIQEE ELEVLLEEEA AGGDEDREKE ILIERIQSIK 
EEKEDITYRL PELDPRGSDE ENLDSETSAS TESLLEERAG RGASEGQY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.