Details for: NELL2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: embryonic stem cell (CL0002322)
Fold Change: 82.6076
Cell Significance Index: -34.0300 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 13.5617
Cell Significance Index: -36.3300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 8.1568
Cell Significance Index: 232.7700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 7.6029
Cell Significance Index: 511.2300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 5.7284
Cell Significance Index: 321.4500 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 5.0365
Cell Significance Index: 38.6300 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 4.9210
Cell Significance Index: -10.7700 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 4.5369
Cell Significance Index: 77.7500 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: 4.1358
Cell Significance Index: 55.1700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 3.1890
Cell Significance Index: 120.7600 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 2.9833
Cell Significance Index: 131.9600 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: 2.9827
Cell Significance Index: 31.0700 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 2.9772
Cell Significance Index: 35.4900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 2.3300
Cell Significance Index: 146.8500 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 2.1529
Cell Significance Index: 47.1400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.1233
Cell Significance Index: 761.6000 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 1.8709
Cell Significance Index: 44.8700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 1.5684
Cell Significance Index: 96.4000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.3353
Cell Significance Index: 254.1100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.0514
Cell Significance Index: 210.9000 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: 0.9281
Cell Significance Index: 10.2400 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.7856
Cell Significance Index: 543.3400 - Cell Name: granule cell (CL0000120)
Fold Change: 0.6790
Cell Significance Index: 7.7300 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.4694
Cell Significance Index: 28.1800 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 0.4305
Cell Significance Index: 13.7100 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: 0.4062
Cell Significance Index: 5.2700 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.4050
Cell Significance Index: 221.1600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.3412
Cell Significance Index: 11.9900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.3285
Cell Significance Index: 296.5700 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.2608
Cell Significance Index: 8.5400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.1997
Cell Significance Index: 21.7200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.1607
Cell Significance Index: 16.7300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1482
Cell Significance Index: 4.2700 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 0.1146
Cell Significance Index: 1.0900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.1081
Cell Significance Index: 68.6500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1023
Cell Significance Index: 192.6600 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.0656
Cell Significance Index: 10.6700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0580
Cell Significance Index: 1.4500 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: 0.0441
Cell Significance Index: 0.4800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0097
Cell Significance Index: 15.0000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0079
Cell Significance Index: 0.7900 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0066
Cell Significance Index: 12.0800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0056
Cell Significance Index: -7.6500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0300
Cell Significance Index: -13.2600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0459
Cell Significance Index: -33.6800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0514
Cell Significance Index: -38.0900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0521
Cell Significance Index: -39.4600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0531
Cell Significance Index: -1.1500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0539
Cell Significance Index: -24.4600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0622
Cell Significance Index: -9.0400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0638
Cell Significance Index: -39.8400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0656
Cell Significance Index: -37.0000 - Cell Name: intratelencephalic-projecting glutamatergic cortical neuron (CL4023008)
Fold Change: -0.0720
Cell Significance Index: -0.7400 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.0770
Cell Significance Index: -0.9600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0941
Cell Significance Index: -5.7700 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.0956
Cell Significance Index: -1.8900 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1014
Cell Significance Index: -29.1700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.1024
Cell Significance Index: -20.3200 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.1121
Cell Significance Index: -2.2500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1250
Cell Significance Index: -14.5700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.1391
Cell Significance Index: -25.0800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.1650
Cell Significance Index: -7.4800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.1736
Cell Significance Index: -12.0100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1909
Cell Significance Index: -40.2100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.2171
Cell Significance Index: -37.0700 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.2325
Cell Significance Index: -28.5900 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.2349
Cell Significance Index: -5.8600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.2575
Cell Significance Index: -35.3600 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.2591
Cell Significance Index: -7.2400 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.2786
Cell Significance Index: -35.9900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.2830
Cell Significance Index: -33.3800 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.2978
Cell Significance Index: -38.1700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.3397
Cell Significance Index: -34.7000 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.3415
Cell Significance Index: -4.8900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.3463
Cell Significance Index: -39.6800 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: -0.3804
Cell Significance Index: -3.1400 - Cell Name: neural cell (CL0002319)
Fold Change: -0.3840
Cell Significance Index: -4.4800 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.4453
Cell Significance Index: -5.6200 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: -0.4504
Cell Significance Index: -2.9300 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.4520
Cell Significance Index: -23.7300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.4560
Cell Significance Index: -35.0000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.4846
Cell Significance Index: -36.1200 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: -0.4909
Cell Significance Index: -6.8700 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.4953
Cell Significance Index: -35.0300 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.5015
Cell Significance Index: -17.5700 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.5065
Cell Significance Index: -10.7500 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: -0.5074
Cell Significance Index: -7.7200 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.5647
Cell Significance Index: -36.4300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.5653
Cell Significance Index: -12.0400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.5667
Cell Significance Index: -29.5200 - Cell Name: neuron (CL0000540)
Fold Change: -0.5744
Cell Significance Index: -5.4500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.6087
Cell Significance Index: -28.6100 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.6427
Cell Significance Index: -16.9000 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.6514
Cell Significance Index: -33.8400 - Cell Name: neuroblast (sensu Nematoda and Protostomia) (CL0000338)
Fold Change: -0.7117
Cell Significance Index: -6.4700 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: -0.7121
Cell Significance Index: -7.9100 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.7183
Cell Significance Index: -24.9600 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: -0.7291
Cell Significance Index: -9.2000 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: -0.7317
Cell Significance Index: -5.3200 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.7691
Cell Significance Index: -16.4400
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2591442636
Symbol: NELL2_HUMAN
Name: Protein kinase C-binding protein NELL2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8975702
Title: Cloning and characterization of two novel human cDNAs (NELL1 and NELL2) encoding proteins with six EGF-like repeats.
PubMed ID: 8975702
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16541075
Title: The finished DNA sequence of human chromosome 12.
PubMed ID: 16541075
DOI: 10.1038/nature04569
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 15340161
Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.
PubMed ID: 15340161
DOI: 10.1110/ps.04682504
PubMed ID: 32198364
Title: NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance.
PubMed ID: 32198364
Sequence Information:
- Length: 816
- Mass: 91346
- Checksum: 89370B987DC7A324
- Sequence:
MESRVLLRTF CLIFGLGAVW GLGVDPSLQI DVLTELELGE STTGVRQVPG LHNGTKAFLF QDTPRSIKAS TATAEQFFQK LRNKHEFTIL VTLKQTHLNS GVILSIHHLD HRYLELESSG HRNEVRLHYR SGSHRPHTEV FPYILADDKW HKLSLAISAS HLILHIDCNK IYERVVEKPS TDLPLGTTFW LGQRNNAHGY FKGIMQDVQL LVMPQGFIAQ CPDLNRTCPT CNDFHGLVQK IMELQDILAK TSAKLSRAEQ RMNRLDQCYC ERTCTMKGTT YREFESWIDG CKNCTCLNGT IQCETLICPN PDCPLKSALA YVDGKCCKEC KSICQFQGRT YFEGERNTVY SSSGVCVLYE CKDQTMKLVE SSGCPALDCP ESHQITLSHS CCKVCKGYDF CSERHNCMEN SICRNLNDRA VCSCRDGFRA LREDNAYCED IDECAEGRHY CRENTMCVNT PGSFMCICKT GYIRIDDYSC TEHDECITNQ HNCDENALCF NTVGGHNCVC KPGYTGNGTT CKAFCKDGCR NGGACIAANV CACPQGFTGP SCETDIDECS DGFVQCDSRA NCINLPGWYH CECRDGYHDN GMFSPSGESC EDIDECGTGR HSCANDTICF NLDGGYDCRC PHGKNCTGDC IHDGKVKHNG QIWVLENDRC SVCSCQNGFV MCRRMVCDCE NPTVDLFCCP ECDPRLSSQC LHQNGETLYN SGDTWVQNCQ QCRCLQGEVD CWPLPCPDVE CEFSILPENE CCPRCVTDPC QADTIRNDIT KTCLDEMNVV RFTGSSWIKH GTECTLCQCK NGHICCSVDP QCLQEL
Genular Protein ID: 4015880335
Symbol: B7Z625_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 866
- Mass: 96849
- Checksum: 5CC916276A4C8A43
- Sequence:
MGFPPLLKGQ ASATRSSLAS CSWVVFFLSC LSRHAPEIEG GRRWTELIRT MESRVLLRTF CLIFGLGAVW GLGVDPSLQI DVLTELELGE STTGVRQVPG LHNGTKAFLF QDTPRSIKAS TATAEQFFQK LRNKHEFTIL VTLKQTHLNS GVILSIHHLD HRYLELESSG HRNEVRLHYR SGSHRPHTEV FPYILADDKW HKLSLAISAS HLILHIDCNK IYERVVEKPS TDLPLGTTFW LGQRNNAHGY FKGIMQDVQL LVMPQGFIAQ CPDLNRTCPT CNDFHGLVQK IMELQDILAK TSAKLSRAEQ RMNRLDQCYC ERTCTMKGTT YREFESWIDG CKNCTCLNGT IQCETLICPN PDCPLKSALA YVDGKCCKEC KSICQFQGRT YFEGERNTVY SSSGVCVLYE CKDQTMELVE SSGCPALDCP ESHQITLSHS CCKVCKGYDF CSERHNCMEN SICRNLNDRA VCSCRDGSRA LREDNAYCED IDECAEGRHY CRENTMCVNT PGSFMCICKT GYIRIDDYSC TEHDECITNQ HNCDENALCF NTVGGHNCVC KPGYTGNGTT CKAFCKDGCR NGGACIAANV CACPQGFTGP SCETDIDECS DGFVQCDSRA NCINLPGWYH CECRDGYHDN GMFSPSGESC EDIDECGTGR HSCANDTICF NLDGGYDCRC PHGKNCTGDC IHDGKVKHNG QIWVLENDRC SVCSCQNGFV MCRRMVCDCE NPTVDLFCCP ECDPRLSSQC LHQNGETLYN SGDTWVQNCQ QCRCLQGEVD CWPLPCPDVE CEFSILPENE CCPRCVTDPC QADTIRNDIT KTCLDEMNVV RFTGSSWIKH GTECTLCQCK NGHICCSVDP RCLQEL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.