Details for: NFKBIB
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 115.7220
Cell Significance Index: -18.0000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 72.2668
Cell Significance Index: -18.3300 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 51.9241
Cell Significance Index: -21.3900 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 43.9504
Cell Significance Index: -20.7500 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 40.6310
Cell Significance Index: -20.9000 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 15.8968
Cell Significance Index: -19.6000 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 6.9321
Cell Significance Index: -18.5700 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 5.1038
Cell Significance Index: -20.1400 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 2.2891
Cell Significance Index: -5.0100 - Cell Name: decidual cell (CL2000002)
Fold Change: 1.3398
Cell Significance Index: 21.5000 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 1.1833
Cell Significance Index: 33.9200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.1727
Cell Significance Index: 16.0000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.0899
Cell Significance Index: 107.8200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.0897
Cell Significance Index: 29.6600 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.8805
Cell Significance Index: 52.8600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.7948
Cell Significance Index: 41.2900 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.7550
Cell Significance Index: 82.1200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.6608
Cell Significance Index: 14.3200 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.5051
Cell Significance Index: 82.1500 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.4633
Cell Significance Index: 21.0000 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.4237
Cell Significance Index: 11.3400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.4191
Cell Significance Index: 19.7000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.3949
Cell Significance Index: 27.3100 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.3660
Cell Significance Index: 10.7500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.3493
Cell Significance Index: 22.5400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.3412
Cell Significance Index: 9.8300 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.3260
Cell Significance Index: 5.7600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.3219
Cell Significance Index: 23.9900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.2895
Cell Significance Index: 34.1400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.2797
Cell Significance Index: 50.4300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.2604
Cell Significance Index: 32.0200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.2595
Cell Significance Index: 29.7300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.2511
Cell Significance Index: 34.4800 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.2474
Cell Significance Index: 31.9700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.2462
Cell Significance Index: 11.4800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2398
Cell Significance Index: 45.6400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.2231
Cell Significance Index: 98.6200 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 0.2216
Cell Significance Index: 1.4500 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.1964
Cell Significance Index: 4.9100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.1891
Cell Significance Index: 170.7100 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.1830
Cell Significance Index: 99.9200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.1783
Cell Significance Index: 4.7600 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: 0.1765
Cell Significance Index: 20.1500 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.1531
Cell Significance Index: 2.8300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.1470
Cell Significance Index: 29.4800 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.1241
Cell Significance Index: 3.3300 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0846
Cell Significance Index: 10.8400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.0705
Cell Significance Index: 3.7000 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0671
Cell Significance Index: 13.3100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.0649
Cell Significance Index: 4.0900 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 0.0634
Cell Significance Index: 0.7200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0584
Cell Significance Index: 9.9700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0441
Cell Significance Index: 15.8000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0414
Cell Significance Index: 2.9300 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.0198
Cell Significance Index: 0.5200 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 0.0184
Cell Significance Index: 0.2800 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: 0.0184
Cell Significance Index: 0.1500 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 0.0065
Cell Significance Index: 0.3300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0020
Cell Significance Index: 0.0700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0009
Cell Significance Index: 0.6800 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0003
Cell Significance Index: 0.6300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0030
Cell Significance Index: -2.1900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0045
Cell Significance Index: -2.8300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0056
Cell Significance Index: -10.3300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0074
Cell Significance Index: -4.1500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0079
Cell Significance Index: -0.2200 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0084
Cell Significance Index: -12.9200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0113
Cell Significance Index: -7.2000 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0133
Cell Significance Index: -18.0300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0155
Cell Significance Index: -11.3400 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0203
Cell Significance Index: -2.0700 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0304
Cell Significance Index: -13.8200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0462
Cell Significance Index: -9.7300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0493
Cell Significance Index: -7.1600 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0541
Cell Significance Index: -15.5800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0550
Cell Significance Index: -6.4100 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.0741
Cell Significance Index: -1.5500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0912
Cell Significance Index: -7.0000 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.1015
Cell Significance Index: -4.1600 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.1016
Cell Significance Index: -1.7000 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.1308
Cell Significance Index: -0.7900 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.1379
Cell Significance Index: -1.2700 - Cell Name: helper T cell (CL0000912)
Fold Change: -0.1682
Cell Significance Index: -2.3900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1856
Cell Significance Index: -19.3300 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.1874
Cell Significance Index: -1.2700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.2184
Cell Significance Index: -12.2600 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: -0.2284
Cell Significance Index: -1.6400 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2324
Cell Significance Index: -18.4100 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.2657
Cell Significance Index: -16.2900 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.2822
Cell Significance Index: -6.0100 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.2940
Cell Significance Index: -7.5100 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.3101
Cell Significance Index: -4.4200 - Cell Name: melanocyte of skin (CL1000458)
Fold Change: -0.3389
Cell Significance Index: -4.7500 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.3403
Cell Significance Index: -3.7000 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.3479
Cell Significance Index: -12.0900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.3595
Cell Significance Index: -15.9000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.3754
Cell Significance Index: -9.6500 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.4005
Cell Significance Index: -14.0300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.4057
Cell Significance Index: -13.0000 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.4127
Cell Significance Index: -15.1500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4053860773
Symbol: IKBB_HUMAN
Name: NF-kappa-B inhibitor beta
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7776974
Title: Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.
PubMed ID: 7776974
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8816457
Title: Role of unphosphorylated, newly synthesized IkappaB beta in persistent activation of NF-kappaB.
PubMed ID: 8816457
PubMed ID: 10657303
Title: A subclass of Ras proteins that regulate the degradation of IkappaB.
PubMed ID: 10657303
PubMed ID: 8657102
Title: Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation.
PubMed ID: 8657102
PubMed ID: 8887627
Title: Basal phosphorylation of the PEST domain in the I(kappa)B(beta) regulates its functional interaction with the c-rel proto-oncogene product.
PubMed ID: 8887627
PubMed ID: 12672800
Title: KappaB-Ras binds to the unique insert within the ankyrin repeat domain of IkappaBbeta and regulates cytoplasmic retention of IkappaBbeta.NF-kappaB complexes.
PubMed ID: 12672800
PubMed ID: 15024091
Title: Inhibition of NF-kappaB activity by IkappaBbeta in association with kappaB-Ras.
PubMed ID: 15024091
PubMed ID: 16573520
Title: Characterization of COMMD protein-protein interactions in NF-kappaB signalling.
PubMed ID: 16573520
DOI: 10.1042/bj20051664
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 356
- Mass: 37771
- Checksum: E84575971B6F81CC
- Sequence:
MAGVACLGKA ADADEWCDSG LGSLGPDAAA PGGPGLGAEL GPGLSWAPLV FGYVTEDGDT ALHLAVIHQH EPFLDFLLGF SAGTEYMDLQ NDLGQTALHL AAILGETSTV EKLYAAGAGL CVAERRGHTA LHLACRVGAH ACARALLQPR PRRPREAPDT YLAQGPDRTP DTNHTPVALY PDSDLEKEEE ESEEDWKLQL EAENYEGHTP LHVAVIHKDV EMVRLLRDAG ADLDKPEPTC GRSPLHLAVE AQAADVLELL LRAGANPAAR MYGGRTPLGS AMLRPNPILA RLLRAHGAPE PEGEDEKSGP CSSSSDSDSG DEGDEYDDIV VHSSRSQTRL PPTPASKPLP DDPRPV
Genular Protein ID: 2939654193
Symbol: G5E9C2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 270
- Mass: 29145
- Checksum: AB74380323EA4CC8
- Sequence:
MDLQNDLGQT ALHLAAILGE TSTVEKLYAA GAGLCVAERR GHTALHLACR VGAHACARAL LQPRPRRPRE APDTYLAQGP DRTPDTNHTP VALYPDSDLE KEEEESEEDW KLQLEAENYE GHTPLHVAVI HKDVEMVRLL RDAGADLDKP EPTCGRSPLH LAVEAQAADV LELLLRAGAN PAARMYGGRT PLGSAMLRPN PILARLLRAH GAPEPEGEDE KSGPCSSSSD SDSGDEGDEY DDIVVHSSRS QTRLPPTPAS KPLPDDPRPV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.