Details for: SLC11A2

Gene ID: 4891

Symbol: SLC11A2

Ensembl ID: ENSG00000110911

Description: solute carrier family 11 member 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 193.5128
    Cell Significance Index: -30.1000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 142.7595
    Cell Significance Index: -36.2100
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 95.4976
    Cell Significance Index: -39.3400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 81.2289
    Cell Significance Index: -38.3500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 75.9371
    Cell Significance Index: -30.8500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 69.4616
    Cell Significance Index: -35.7300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 32.3438
    Cell Significance Index: -30.8800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 29.4090
    Cell Significance Index: -36.2600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 13.6812
    Cell Significance Index: -36.6500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 11.3497
    Cell Significance Index: -34.8600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 9.5589
    Cell Significance Index: -37.7200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 8.4758
    Cell Significance Index: -18.5500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.3246
    Cell Significance Index: 265.7100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.2358
    Cell Significance Index: 245.2400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.9563
    Cell Significance Index: 104.0200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.7864
    Cell Significance Index: 282.0500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.7842
    Cell Significance Index: 47.0800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.7269
    Cell Significance Index: 33.8900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.7055
    Cell Significance Index: 39.5900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.6785
    Cell Significance Index: 31.8900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.5968
    Cell Significance Index: 412.8000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.4408
    Cell Significance Index: 12.3200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4324
    Cell Significance Index: 29.9100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.3744
    Cell Significance Index: 10.1900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3608
    Cell Significance Index: 18.7400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3201
    Cell Significance Index: 174.8000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2641
    Cell Significance Index: 7.6100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2639
    Cell Significance Index: 32.4600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2322
    Cell Significance Index: 41.8600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1874
    Cell Significance Index: 352.9400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1843
    Cell Significance Index: 14.1400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1350
    Cell Significance Index: 6.1200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1266
    Cell Significance Index: 24.1000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1167
    Cell Significance Index: 51.5900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0996
    Cell Significance Index: 17.0100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0854
    Cell Significance Index: 54.2200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0837
    Cell Significance Index: 75.5900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0608
    Cell Significance Index: 3.7400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0586
    Cell Significance Index: 79.6300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0560
    Cell Significance Index: 86.2100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.0530
    Cell Significance Index: 1.5200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0517
    Cell Significance Index: 95.4200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0199
    Cell Significance Index: 2.7400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0178
    Cell Significance Index: 1.2000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0166
    Cell Significance Index: 7.5400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0017
    Cell Significance Index: 0.0600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0011
    Cell Significance Index: -0.0300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0041
    Cell Significance Index: -0.5300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0062
    Cell Significance Index: -0.7900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0113
    Cell Significance Index: -7.0400
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0147
    Cell Significance Index: -0.1200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0148
    Cell Significance Index: -10.9600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.0167
    Cell Significance Index: -1.6500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0178
    Cell Significance Index: -13.4800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0285
    Cell Significance Index: -20.9200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0404
    Cell Significance Index: -22.7600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0494
    Cell Significance Index: -3.6800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0621
    Cell Significance Index: -7.1200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0747
    Cell Significance Index: -4.7100
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0769
    Cell Significance Index: -8.7800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0825
    Cell Significance Index: -8.4300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1022
    Cell Significance Index: -21.5300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1033
    Cell Significance Index: -12.0400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1118
    Cell Significance Index: -32.1600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1149
    Cell Significance Index: -16.7000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1427
    Cell Significance Index: -6.3100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1451
    Cell Significance Index: -5.5000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2146
    Cell Significance Index: -22.3500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2150
    Cell Significance Index: -13.8700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2192
    Cell Significance Index: -15.5000
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.2283
    Cell Significance Index: -5.5700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2381
    Cell Significance Index: -12.5000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2410
    Cell Significance Index: -28.4200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2626
    Cell Significance Index: -4.5000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.2631
    Cell Significance Index: -5.7600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2673
    Cell Significance Index: -8.5600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.3151
    Cell Significance Index: -6.7100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.3776
    Cell Significance Index: -9.4400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.4183
    Cell Significance Index: -21.7900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4198
    Cell Significance Index: -33.2500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4460
    Cell Significance Index: -15.5000
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.4515
    Cell Significance Index: -5.6000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4536
    Cell Significance Index: -11.6600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.4916
    Cell Significance Index: -14.0300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.4918
    Cell Significance Index: -6.7100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4998
    Cell Significance Index: -30.6400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.5133
    Cell Significance Index: -11.1200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.5508
    Cell Significance Index: -13.2100
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.5564
    Cell Significance Index: -12.8600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.5804
    Cell Significance Index: -12.0400
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.5936
    Cell Significance Index: -6.1500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.5987
    Cell Significance Index: -10.0200
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.6213
    Cell Significance Index: -10.4700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.6225
    Cell Significance Index: -16.6800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.6832
    Cell Significance Index: -14.5000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.6917
    Cell Significance Index: -22.0300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.7181
    Cell Significance Index: -23.5100
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.7268
    Cell Significance Index: -11.6600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.7680
    Cell Significance Index: -14.9900
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.7690
    Cell Significance Index: -11.3500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Function:** SLC11A2 is a transmembrane protein that functions as a ferrous iron transporter, responsible for importing iron into cells through the apical plasma membrane. 2. **Structure:** The protein consists of 12 transmembrane domains, which create a pore-like structure that allows iron ions to pass through. 3. **Expression:** SLC11A2 is highly expressed in cells involved in iron metabolism, including erythrocytes, renal principal cells, and pigmented epithelial cells. 4. **Regulation:** The protein is regulated by various mechanisms, including pH-dependent transport, which allows it to adapt to changes in the cellular environment. **Pathways and Functions:** 1. **Iron Uptake and Homeostasis:** SLC11A2 plays a critical role in maintaining iron homeostasis by regulating the uptake of iron into cells. 2. **Apical Plasma Membrane Transport:** The protein is transported to the apical plasma membrane, where it can bind and transport iron ions. 3. **Mitochondrial Iron Uptake:** SLC11A2 has been shown to facilitate the uptake of iron into mitochondria, which is essential for energy production. 4. **Immune Function:** The protein is also involved in the regulation of immune function, particularly in the context of iron-dependent immune responses. **Clinical Significance:** 1. **Hypochromic Microcytic Anemia with Iron Overload (AHMIO1):** Mutations in the SLC11A2 gene have been implicated in this disorder, which is characterized by anemia, iron overload, and other complications. 2. **Iron-Dependent Disorders:** SLC11A2 dysfunction has been linked to various iron-dependent disorders, including hemochromatosis and sideroblastic anemia. 3. **Cancer and Immune System:** The protein's role in immune function and iron metabolism makes it an important target for research in cancer and immunology. 4. **Nutritional and Environmental Factors:** SLC11A2 expression and function can be influenced by nutritional and environmental factors, such as iron supplements and exposure to heavy metals. In conclusion, SLC11A2 is a critical gene involved in iron uptake and homeostasis, and its dysfunction can lead to various disorders. Further research is needed to fully understand the complexities of this gene and its role in human health and disease.

Genular Protein ID: 3750281510

Symbol: NRAM2_HUMAN

Name: Natural resistance-associated macrophage protein 2

UniProtKB Accession Codes:

P49281 B3KT08 B4DK84 F5H741 O43288 O60932 O94801 Q498Z5 Q8IUD7 Q96J35

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CORUM 1 CTD 1 ChEBI 30 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 5 EMBL 29 Ensembl 8 ExpressionAtlas 1 GO 63 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HAMAP 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 2 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 5 PIR 1 PRINTS 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 Reactome 3 RefSeq 11 Rhea 36 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9464519

Title: Complete nucleotide sequence of human NRAMP2 cDNA.

PubMed ID: 9464519

DOI: 10.1016/s0161-5890(97)00110-7

PubMed ID: 9790986

Title: Human natural resistance-associated macrophage protein 2: gene cloning and protein identification.

PubMed ID: 9790986

DOI: 10.1006/bbrc.1998.9415

PubMed ID: 9642100

Title: The human Nramp2 gene: characterization of the gene structure, alternative splicing, promoter region and polymorphisms.

PubMed ID: 9642100

DOI: 10.1006/bcmd.1998.0186

PubMed ID: 12209011

Title: Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function.

PubMed ID: 12209011

DOI: 10.1073/pnas.192423399

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7613023

Title: Cloning and characterization of a second human NRAMP gene on chromosome 12q13.

PubMed ID: 7613023

DOI: 10.1007/bf00352405

PubMed ID: 12475959

Title: Alternative splicing regulates the subcellular localization of divalent metal transporter 1 isoforms.

PubMed ID: 12475959

DOI: 10.1091/mbc.e02-03-0165

PubMed ID: 17109629

Title: Functional properties of multiple isoforms of human divalent metal-ion transporter 1 (DMT1).

PubMed ID: 17109629

DOI: 10.1042/bj20061290

PubMed ID: 17293870

Title: Ca2+ channel blockers reverse iron overload by a new mechanism via divalent metal transporter-1.

PubMed ID: 17293870

DOI: 10.1038/nm1542

PubMed ID: 19706893

Title: Divalent metal transporter 1 (DMT1) regulation by Ndfip1 prevents metal toxicity in human neurons.

PubMed ID: 19706893

DOI: 10.1073/pnas.0904880106

PubMed ID: 22736759

Title: Substrate profile and metal-ion selectivity of human divalent metal-ion transporter-1.

PubMed ID: 22736759

DOI: 10.1074/jbc.m112.364208

PubMed ID: 25491917

Title: Inhibition of iron uptake by ferristatin II is exerted through internalization of DMT1 at the plasma membrane.

PubMed ID: 25491917

DOI: 10.1002/cbin.10403

PubMed ID: 24448823

Title: Evidence for mitochondrial localization of divalent metal transporter 1 (DMT1).

PubMed ID: 24448823

DOI: 10.1096/fj.13-240564

PubMed ID: 25326704

Title: Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport.

PubMed ID: 25326704

DOI: 10.1038/nsmb.2904

PubMed ID: 27462458

Title: Regulation of the divalent metal ion transporter via membrane budding.

PubMed ID: 27462458

DOI: 10.1038/celldisc.2016.11

PubMed ID: 29317744

Title: A role for divalent metal transporter (DMT1) in mitochondrial uptake of iron and manganese.

PubMed ID: 29317744

DOI: 10.1038/s41598-017-18584-4

PubMed ID: 15459009

Title: Identification of a human mutation of DMT1 in a patient with microcytic anemia and iron overload.

PubMed ID: 15459009

DOI: 10.1182/blood-2004-07-2966

PubMed ID: 16160008

Title: Microcytic anemia and hepatic iron overload in a child with compound heterozygous mutations in DMT1 (SCL11A2).

PubMed ID: 16160008

DOI: 10.1182/blood-2005-06-2477

PubMed ID: 16439678

Title: Two new human DMT1 gene mutations in a patient with microcytic anemia, low ferritinemia, and liver iron overload.

PubMed ID: 16439678

DOI: 10.1182/blood-2005-10-4269

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 568
  • Mass: 62266
  • Checksum: 4E45D6A448A23263
  • Sequence:
    • MVLGPEQKMS DDSVSGDHGE SASLGNINPA YSNPSLSQSP GDSEEYFATY FNEKISIPEE 
EYSCFSFRKL WAFTGPGFLM SIAYLDPGNI ESDLQSGAVA GFKLLWILLL ATLVGLLLQR 
LAARLGVVTG LHLAEVCHRQ YPKVPRVILW LMVELAIIGS DMQEVIGSAI AINLLSVGRI 
PLWGGVLITI ADTFVFLFLD KYGLRKLEAF FGFLITIMAL TFGYEYVTVK PSQSQVLKGM 
FVPSCSGCRT PQIEQAVGIV GAVIMPHNMY LHSALVKSRQ VNRNNKQEVR EANKYFFIES 
CIALFVSFII NVFVVSVFAE AFFGKTNEQV VEVCTNTSSP HAGLFPKDNS TLAVDIYKGG 
VVLGCYFGPA ALYIWAVGIL AAGQSSTMTG TYSGQFVMEG FLNLKWSRFA RVVLTRSIAI 
IPTLLVAVFQ DVEHLTGMND FLNVLQSLQL PFALIPILTF TSLRPVMSDF ANGLGWRIAG 
GILVLIICSI NMYFVVVYVR DLGHVALYVV AAVVSVAYLG FVFYLGWQCL IALGMSFLDC 
GHTCHLGLTA QPELYLLNTM DADSLVSR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.