Details for: OSBP

Gene ID: 5007

Symbol: OSBP

Ensembl ID: ENSG00000110048

Description: oxysterol binding protein

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 218.3931
    Cell Significance Index: -33.9700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 131.1684
    Cell Significance Index: -33.2700
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 76.9080
    Cell Significance Index: -36.3100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 72.4664
    Cell Significance Index: -29.4400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 31.0764
    Cell Significance Index: -29.6700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 28.1113
    Cell Significance Index: -34.6600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 13.1138
    Cell Significance Index: -35.1300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.8139
    Cell Significance Index: -34.7800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 7.5241
    Cell Significance Index: -23.1100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 6.2049
    Cell Significance Index: -13.5800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 4.2171
    Cell Significance Index: 417.1600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.7246
    Cell Significance Index: 23.5300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 1.5735
    Cell Significance Index: 14.4900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.5540
    Cell Significance Index: 169.0300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.1555
    Cell Significance Index: 187.9300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.1043
    Cell Significance Index: 199.0700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.0524
    Cell Significance Index: 211.1200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.0453
    Cell Significance Index: 27.9100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.9114
    Cell Significance Index: 180.8800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.8627
    Cell Significance Index: 23.1200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.8305
    Cell Significance Index: 20.7600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.8277
    Cell Significance Index: 57.2400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.7218
    Cell Significance Index: 88.7600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.7140
    Cell Significance Index: 37.0900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.6424
    Cell Significance Index: 88.2200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.6162
    Cell Significance Index: 17.7600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.6079
    Cell Significance Index: 27.5600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.5722
    Cell Significance Index: 26.6800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.5550
    Cell Significance Index: 15.5100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4964
    Cell Significance Index: 448.2200
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.4779
    Cell Significance Index: 8.0500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.4763
    Cell Significance Index: 36.5500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.4365
    Cell Significance Index: 11.8800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4347
    Cell Significance Index: 155.9100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3869
    Cell Significance Index: 211.3000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.3540
    Cell Significance Index: 244.8600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.3492
    Cell Significance Index: 154.3800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.3161
    Cell Significance Index: 53.9800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.2777
    Cell Significance Index: 19.6400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.2216
    Cell Significance Index: 14.3000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2149
    Cell Significance Index: 10.1000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.2062
    Cell Significance Index: 9.1200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2002
    Cell Significance Index: 38.0900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.1597
    Cell Significance Index: 8.9600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.1439
    Cell Significance Index: 5.4500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.1085
    Cell Significance Index: 3.1100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0670
    Cell Significance Index: 4.2200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0526
    Cell Significance Index: 1.1200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0526
    Cell Significance Index: 6.0300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0482
    Cell Significance Index: 30.6200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0480
    Cell Significance Index: 90.4400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0434
    Cell Significance Index: 19.6900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0307
    Cell Significance Index: 1.6000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0223
    Cell Significance Index: 16.3300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0081
    Cell Significance Index: 12.4600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0077
    Cell Significance Index: 14.2500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0059
    Cell Significance Index: 8.0500
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.0066
    Cell Significance Index: -0.1000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0071
    Cell Significance Index: -5.2700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0103
    Cell Significance Index: -6.4600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0166
    Cell Significance Index: -2.1300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0245
    Cell Significance Index: -18.5600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0259
    Cell Significance Index: -14.6000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0299
    Cell Significance Index: -4.3500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0407
    Cell Significance Index: -1.4300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0555
    Cell Significance Index: -7.1700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.0589
    Cell Significance Index: -1.3600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0622
    Cell Significance Index: -4.1800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0840
    Cell Significance Index: -17.7000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0850
    Cell Significance Index: -8.6800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0871
    Cell Significance Index: -6.4900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0957
    Cell Significance Index: -5.8900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.1030
    Cell Significance Index: -2.0100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1040
    Cell Significance Index: -29.9300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1107
    Cell Significance Index: -12.9100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1118
    Cell Significance Index: -13.1800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1374
    Cell Significance Index: -15.6800
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.1506
    Cell Significance Index: -0.9100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.2391
    Cell Significance Index: -5.1800
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.2456
    Cell Significance Index: -3.9400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2674
    Cell Significance Index: -27.8400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3009
    Cell Significance Index: -23.8300
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.3341
    Cell Significance Index: -8.1500
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.3381
    Cell Significance Index: -4.9900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.3460
    Cell Significance Index: -5.9300
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.3716
    Cell Significance Index: -3.0300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4170
    Cell Significance Index: -25.5700
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.4233
    Cell Significance Index: -2.7600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4420
    Cell Significance Index: -6.5200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4538
    Cell Significance Index: -23.8300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.4811
    Cell Significance Index: -9.9800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.4852
    Cell Significance Index: -10.6300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.5439
    Cell Significance Index: -15.5200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.5813
    Cell Significance Index: -8.7100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5830
    Cell Significance Index: -15.3300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.5921
    Cell Significance Index: -15.2200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5945
    Cell Significance Index: -20.6600
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.6231
    Cell Significance Index: -8.8700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.6741
    Cell Significance Index: -21.4700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.6936
    Cell Significance Index: -14.7200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** OSBP is a member of the OSBP-related protein family and is characterized by its ability to bind oxysterols, phosphatidylinositol-4-phosphate (PI4P), and other lipids. It is a large protein, consisting of 659 amino acids, and is localized to the ER, Golgi apparatus, and plasma membrane. OSBP is highly expressed in various cell types, including conjunctival epithelial cells, mural cells, and neurons. Its expression is also observed in immune cells, such as innate lymphoid cells, and in cardiac muscle myoblasts. **Pathways and Functions:** OSBP is involved in several critical pathways, including: 1. **Bile acid and bile salt metabolism:** OSBP plays a key role in the synthesis, transport, and metabolism of bile acids, which are essential for fat digestion and absorption. 2. **Intracellular cholesterol transport:** OSBP is involved in the transport of cholesterol within the cell, regulating its availability for various cellular processes, including lipid synthesis and cell signaling. 3. **Sphingolipid de novo biosynthesis:** OSBP is required for the synthesis of sphingolipids, which are essential components of cellular membranes. 4. **Insulin secretion and glucose metabolism:** OSBP is involved in the regulation of insulin secretion and glucose metabolism, making it a potential therapeutic target for the treatment of diabetes. 5. **Cell signaling and membrane trafficking:** OSBP is involved in various cell signaling pathways, including the regulation of insulin secretion, secretory granule organization, and tyrosine phosphorylation of stat protein. **Clinical Significance:** OSBP has been implicated in various diseases, including: 1. **Diabetes:** OSBP has been shown to play a critical role in insulin secretion and glucose metabolism, making it a potential therapeutic target for the treatment of diabetes. 2. **Atherosclerosis:** OSBP has been implicated in the development of atherosclerosis, a disease characterized by the buildup of lipids in the arterial walls. 3. **Neurodegenerative diseases:** OSBP has been shown to play a role in the regulation of sphingolipid metabolism, which is essential for the maintenance of neuronal function and integrity. 4. **Cardiovascular disease:** OSBP has been implicated in the regulation of cholesterol transport and metabolism, making it a potential therapeutic target for the treatment of cardiovascular disease. In conclusion, OSBP is a multifunctional protein that plays a critical role in various cellular processes, including lipid metabolism, cell signaling, and transport. Its unique ability to bind oxysterols makes it an essential regulator of lipid homeostasis and cellular function. Further research is needed to fully elucidate the mechanisms of OSBP and its clinical significance, but it is clear that OSBP is a key player in the regulation of lipid metabolism and cellular function.

Genular Protein ID: 1121770063

Symbol: OSBP1_HUMAN

Name: N/A

UniProtKB Accession Codes:

P22059 Q6P524

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEBI 8 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 ELM 1 EMBL 13 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 27 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissLipids 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1970801

Title: cDNA cloning of human oxysterol-binding protein and localization of the gene to human chromosome 11 and mouse chromosome 19.

PubMed ID: 1970801

DOI: 10.1016/0888-7543(90)90519-z

PubMed ID: 11278871

Title: Molecular and biochemical characterization of a novel oxysterol-binding protein (OSBP2) highly expressed in retina.

PubMed ID: 11278871

DOI: 10.1074/jbc.m011259200

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15746430

Title: OSBP is a cholesterol-regulated scaffolding protein in control of ERK 1/2 activation.

PubMed ID: 15746430

DOI: 10.1126/science.1107710

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17428193

Title: The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket.

PubMed ID: 17428193

DOI: 10.1042/bj20070176

PubMed ID: 18450749

Title: OSBP negatively regulates ABCA1 protein stability.

PubMed ID: 18450749

DOI: 10.1074/jbc.m800918200

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 24209621

Title: A four-step cycle driven by PI(4)P hydrolysis directs sterol/PI(4)P exchange by the ER-Golgi tether OSBP.

PubMed ID: 24209621

DOI: 10.1016/j.cell.2013.09.056

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 20178991

Title: Electrostatic interaction between oxysterol-binding protein and VAMP-associated protein A revealed by NMR and mutagenesis studies.

PubMed ID: 20178991

DOI: 10.1074/jbc.m109.082602

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 29514919

Title: The Rab11-binding protein RELCH/KIAA1468 controls intracellular cholesterol distribution.

PubMed ID: 29514919

DOI: 10.1083/jcb.201709123

Sequence Information:

  • Length: 807
  • Mass: 89421
  • Checksum: 2590A47BCB54FDFB
  • Sequence:
    • MAATELRGVV GPGPAAIAAL GGGGAGPPVV GGGGGRGDAG PGSGAASGTV VAAAAGGPGP 
GAGGVAAAGP APAPPTGGSG GSGAGGSGSA REGWLFKWTN YIKGYQRRWF VLSNGLLSYY 
RSKAEMRHTC RGTINLATAN ITVEDSCNFI ISNGGAQTYH LKASSEVERQ RWVTALELAK 
AKAVKMLAES DESGDEESVS QTDKTELQNT LRTLSSKVED LSTCNDLIAK HGTALQRSLS 
ELESLKLPAE SNEKIKQVNE RATLFRITSN AMINACRDFL MLAQTHSKKW QKSLQYERDQ 
RIRLEETLEQ LAKQHNHLER AFRGATVLPA NTPGNVGSGK DQCCSGKGDM SDEDDENEFF 
DAPEIITMPE NLGHKRTGSN ISGASSDISL DEQYKHQLEE TKKEKRTRIP YKPNYSLNLW 
SIMKNCIGKE LSKIPMPVNF NEPLSMLQRL TEDLEYHELL DRAAKCENSL EQLCYVAAFT 
VSSYSTTVFR TSKPFNPLLG ETFELDRLEE NGYRSLCEQV SHHPPAAAHH AESKNGWTLR 
QEIKITSKFR GKYLSIMPLG TIHCIFHATG HHYTWKKVTT TVHNIIVGKL WIDQSGEIDI 
VNHKTGDKCN LKFVPYSYFS RDVARKVTGE VTDPSGKVHF ALLGTWDEKM ECFKVQPVIG 
ENGGDARQRG HEAEESRVML WKRNPLPKNA ENMYYFSELA LTLNAWESGT APTDSRLRPD 
QRLMENGRWD EANAEKQRLE EKQRLSRKKR EAEAMKATED GTPYDPYKAL WFERKKDPVT 
KELTHIYRGE YWECKEKQDW SSCPDIF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.