Details for: PCBP1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 469.9276
Cell Significance Index: -73.1000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 322.7366
Cell Significance Index: -81.8600 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 284.2594
Cell Significance Index: -117.1000 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 237.5589
Cell Significance Index: -96.5100 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 219.4133
Cell Significance Index: -103.5900 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 204.5743
Cell Significance Index: -105.2300 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 155.3302
Cell Significance Index: -104.2300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 77.8292
Cell Significance Index: -95.9600 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 26.1680
Cell Significance Index: -103.2600 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 24.8384
Cell Significance Index: -76.2900 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 24.0438
Cell Significance Index: -64.4100 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 12.9536
Cell Significance Index: -28.3500 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 4.7845
Cell Significance Index: 88.4300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 3.4491
Cell Significance Index: 257.0600 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 3.2409
Cell Significance Index: 41.5100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 2.9345
Cell Significance Index: 346.0700 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 2.7054
Cell Significance Index: 440.0100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 2.6112
Cell Significance Index: 122.7300 - Cell Name: granulosa cell (CL0000501)
Fold Change: 2.4881
Cell Significance Index: 65.4300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 2.4218
Cell Significance Index: 332.5800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 2.3522
Cell Significance Index: 151.7600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 2.3281
Cell Significance Index: 286.2600 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 2.2804
Cell Significance Index: 62.0700 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 2.2536
Cell Significance Index: 18.9300 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 2.2278
Cell Significance Index: 63.8600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 2.1118
Cell Significance Index: 380.7000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 2.0949
Cell Significance Index: 1144.0800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 2.0517
Cell Significance Index: 141.8900 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 2.0344
Cell Significance Index: 12.5200 - Cell Name: lactocyte (CL0002325)
Fold Change: 2.0181
Cell Significance Index: 260.7200 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 1.9934
Cell Significance Index: 69.2700 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 1.8643
Cell Significance Index: 824.2700 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 1.8121
Cell Significance Index: 37.9300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.7540
Cell Significance Index: 81.7800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 1.6864
Cell Significance Index: 119.2700 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: 1.5440
Cell Significance Index: 17.5400 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 1.3380
Cell Significance Index: 23.6500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.2093
Cell Significance Index: 32.2900 - Cell Name: odontoblast (CL0000060)
Fold Change: 1.2006
Cell Significance Index: 153.9100 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.1913
Cell Significance Index: 71.5200 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: 1.1875
Cell Significance Index: 12.9100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.9496
Cell Significance Index: 188.4500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.7702
Cell Significance Index: 131.5200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.7592
Cell Significance Index: 39.4400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.7370
Cell Significance Index: 21.2400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.3887
Cell Significance Index: 77.9800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.3449
Cell Significance Index: 65.6300 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.2454
Cell Significance Index: 2.2600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.1140
Cell Significance Index: 86.2800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0981
Cell Significance Index: 35.1800 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 0.0748
Cell Significance Index: 0.8000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.0687
Cell Significance Index: 6.8000 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0092
Cell Significance Index: 6.7800 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0006
Cell Significance Index: -0.0100 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.0114
Cell Significance Index: -0.3000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0173
Cell Significance Index: -12.7900 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0296
Cell Significance Index: -55.7800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0339
Cell Significance Index: -1.7800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: -0.0408
Cell Significance Index: -36.8000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0559
Cell Significance Index: -34.9300 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0607
Cell Significance Index: -82.5000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0680
Cell Significance Index: -125.3800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0753
Cell Significance Index: -7.7000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0795
Cell Significance Index: -122.4300 - Cell Name: peg cell (CL4033014)
Fold Change: -0.1177
Cell Significance Index: -2.7200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.1341
Cell Significance Index: -85.1500 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1342
Cell Significance Index: -75.6900 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.2082
Cell Significance Index: -2.9200 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.2123
Cell Significance Index: -24.2300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.2126
Cell Significance Index: -96.4700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2206
Cell Significance Index: -46.4600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.2905
Cell Significance Index: -31.6000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2948
Cell Significance Index: -84.8300 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.4011
Cell Significance Index: -25.2800 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.4549
Cell Significance Index: -52.1200 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.5362
Cell Significance Index: -62.4900 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.5564
Cell Significance Index: -11.8500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.6309
Cell Significance Index: -22.1700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.6593
Cell Significance Index: -95.8400 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.7054
Cell Significance Index: -18.0200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.7131
Cell Significance Index: -15.4500 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.8172
Cell Significance Index: -11.1500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.8591
Cell Significance Index: -24.0100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.9102
Cell Significance Index: -72.0900 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: -0.9616
Cell Significance Index: -5.8100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.9749
Cell Significance Index: -65.5500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.9811
Cell Significance Index: -102.1600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -1.1330
Cell Significance Index: -69.6400 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -1.2317
Cell Significance Index: -36.1800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -1.2346
Cell Significance Index: -55.9600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -1.2963
Cell Significance Index: -99.4800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -1.3784
Cell Significance Index: -77.3500 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -1.4540
Cell Significance Index: -38.9600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -1.5202
Cell Significance Index: -48.6900 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -1.5825
Cell Significance Index: -82.4300 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -1.6358
Cell Significance Index: -28.2000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -1.6703
Cell Significance Index: -42.9400 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -1.6951
Cell Significance Index: -25.4000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.7076
Cell Significance Index: -104.6900 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -1.8518
Cell Significance Index: -19.1700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2521290461
Symbol: PCBP1_HUMAN
Name: Heterogeneous nuclear ribonucleoprotein E1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7607214
Title: Characterisation of two major cellular poly(rC)-binding human proteins, each containing three K-homologous (KH) domains.
PubMed ID: 7607214
PubMed ID: 7556077
Title: Identification of two KH domain proteins in the alpha-globin mRNP stability complex.
PubMed ID: 7556077
PubMed ID: 8152927
Title: Tissue specific expression and cDNA structure of a human transcript encoding a nucleic acid binding [oligo(dC)] protein related to the pre-mRNA binding protein K.
PubMed ID: 8152927
DOI: 10.1093/nar/22.6.959
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12414943
Title: Distinct poly(rC) binding protein KH domain determinants for poliovirus translation initiation and viral RNA replication.
PubMed ID: 12414943
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 16964243
Title: A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
PubMed ID: 16964243
DOI: 10.1038/nbt1240
PubMed ID: 17924679
Title: Improved titanium dioxide enrichment of phosphopeptides from HeLa cells and high confident phosphopeptide identification by cross-validation of MS/MS and MS/MS/MS spectra.
PubMed ID: 17924679
DOI: 10.1021/pr070152u
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 15731341
Title: Structure and RNA binding of the third KH domain of poly(C)-binding protein 1.
PubMed ID: 15731341
DOI: 10.1093/nar/gki265
Sequence Information:
- Length: 356
- Mass: 37498
- Checksum: 6D1A261276CA206D
- Sequence:
MDAGVTESGL NVTLTIRLLM HGKEVGSIIG KKGESVKRIR EESGARINIS EGNCPERIIT LTGPTNAIFK AFAMIIDKLE EDINSSMTNS TAASRPPVTL RLVVPATQCG SLIGKGGCKI KEIRESTGAQ VQVAGDMLPN STERAITIAG VPQSVTECVK QICLVMLETL SQSPQGRVMT IPYQPMPASS PVICAGGQDR CSDAAGYPHA THDLEGPPLD AYSIQGQHTI SPLDLAKLNQ VARQQSHFAM MHGGTGFAGI DSSSPEVKGY WASLDASTQT THELTIPNNL IGCIIGRQGA NINEIRQMSG AQIKIANPVE GSSGRQVTIT GSAASISLAQ YLINARLSSE KGMGCS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.