Details for: KLHL5
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 225.7864
Cell Significance Index: -35.1200 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 133.2580
Cell Significance Index: -33.8000 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 75.7430
Cell Significance Index: -35.7600 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 75.5310
Cell Significance Index: -30.6900 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 68.0618
Cell Significance Index: -35.0100 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 32.1605
Cell Significance Index: -30.7100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 28.6709
Cell Significance Index: -35.3500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 13.0279
Cell Significance Index: -34.9000 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 11.7501
Cell Significance Index: -36.0900 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 11.1579
Cell Significance Index: -24.4200 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 8.9938
Cell Significance Index: -35.4900 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 5.9640
Cell Significance Index: 130.5900 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 5.1620
Cell Significance Index: 64.0300 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 2.9272
Cell Significance Index: 42.1000 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 2.9128
Cell Significance Index: 195.8600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.5130
Cell Significance Index: 287.9300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.4709
Cell Significance Index: 66.6700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.3788
Cell Significance Index: 273.6300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 1.3011
Cell Significance Index: 79.9700 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 1.1455
Cell Significance Index: 32.6900 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.1034
Cell Significance Index: 29.5700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.8442
Cell Significance Index: 169.3400 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.7925
Cell Significance Index: 548.1100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6766
Cell Significance Index: 66.9400 - Cell Name: chandelier cell (CL4023083)
Fold Change: 0.6539
Cell Significance Index: 5.2800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6526
Cell Significance Index: 589.2200 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.5394
Cell Significance Index: 28.1000 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.5214
Cell Significance Index: 5.4000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.4109
Cell Significance Index: 147.3800 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.4040
Cell Significance Index: 9.6900 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.3758
Cell Significance Index: 6.3300 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3369
Cell Significance Index: 54.7900 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.2795
Cell Significance Index: 7.8100 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.2598
Cell Significance Index: 141.8800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.2462
Cell Significance Index: 29.0300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.2176
Cell Significance Index: 26.7500 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.1948
Cell Significance Index: 21.1900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.1603
Cell Significance Index: 11.9500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1228
Cell Significance Index: 16.8600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1207
Cell Significance Index: 227.3300 - Cell Name: endothelial cell of placenta (CL0009092)
Fold Change: 0.1192
Cell Significance Index: 0.7200 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.0819
Cell Significance Index: 4.3000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0703
Cell Significance Index: 108.2700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0688
Cell Significance Index: 126.8200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0600
Cell Significance Index: 10.8100 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0461
Cell Significance Index: 0.7900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0287
Cell Significance Index: 13.0300 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0163
Cell Significance Index: 22.1200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.0135
Cell Significance Index: 0.7600 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.0121
Cell Significance Index: 0.2400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0036
Cell Significance Index: 1.5800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0044
Cell Significance Index: -2.8000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0097
Cell Significance Index: -0.3400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0149
Cell Significance Index: -9.3200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0183
Cell Significance Index: -13.5800 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0293
Cell Significance Index: -21.4800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0360
Cell Significance Index: -5.2400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0366
Cell Significance Index: -20.6300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0385
Cell Significance Index: -6.5800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0460
Cell Significance Index: -34.8000 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0602
Cell Significance Index: -7.7200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0784
Cell Significance Index: -2.2600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0833
Cell Significance Index: -17.5500 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.0884
Cell Significance Index: -5.3100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1061
Cell Significance Index: -30.5200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1105
Cell Significance Index: -11.2900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1227
Cell Significance Index: -9.4200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.1246
Cell Significance Index: -2.7000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1413
Cell Significance Index: -16.4700 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1483
Cell Significance Index: -19.1600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1599
Cell Significance Index: -18.3200 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1729
Cell Significance Index: -3.6700 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.2131
Cell Significance Index: -4.5600 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.2250
Cell Significance Index: -15.5600 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.2280
Cell Significance Index: -3.2700 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.2444
Cell Significance Index: -10.8100 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2465
Cell Significance Index: -4.8100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2515
Cell Significance Index: -11.8200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2603
Cell Significance Index: -27.1000 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.2632
Cell Significance Index: -30.0400 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.2723
Cell Significance Index: -10.3100 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2819
Cell Significance Index: -9.2300 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: -0.2945
Cell Significance Index: -4.4800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.3057
Cell Significance Index: -19.7200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.3429
Cell Significance Index: -21.0200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.3528
Cell Significance Index: -16.4500 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.3587
Cell Significance Index: -5.3000 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: -0.3609
Cell Significance Index: -4.6800 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3947
Cell Significance Index: -31.2600 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.4017
Cell Significance Index: -10.7500 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.4376
Cell Significance Index: -30.9500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.4385
Cell Significance Index: -22.7800 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.4395
Cell Significance Index: -9.3600 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.4500
Cell Significance Index: -14.3300 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.4571
Cell Significance Index: -7.6500 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.5285
Cell Significance Index: -10.6100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.5667
Cell Significance Index: -35.7200 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.5907
Cell Significance Index: -18.9200 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.6074
Cell Significance Index: -12.6000 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.6142
Cell Significance Index: -15.3200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1960528727
Symbol: KLHL5_HUMAN
Name: Kelch-like protein 5
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11590829
Title: Cloning and characterization of KLHL5, a novel human gene encoding a kelch-related protein with a BTB domain.
PubMed ID: 11590829
PubMed ID: 14672410
Title: Characterization of a novel splicing variant of KLHL5, a member of the kelch protein family.
PubMed ID: 14672410
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 755
- Mass: 84457
- Checksum: 2AB1BFB98F387F6C
- Sequence:
MNVIYFPLHI FVVYSRAYTS LVLVGCTNLC AVLFARCLDD HLVSLRMSGS RKEFDVKQIL KIRWRWFGHQ ASSPNSTVDS QQGEFWNRGQ TGANGGRKFL DPCSLQLPLA SIGYRRSSQL DFQNSPSWPM ASTSEVPAFE FTAEDCGGAH WLDRPEVDDG TSEEENESDS SSCRTSNSSQ TLSSCHTMEP CTSDEFFQAL NHAEQTFKKM ENYLRHKQLC DVILVAGDRR IPAHRLVLSS VSDYFAAMFT NDVREARQEE IKMEGVEPNS LWSLIQYAYT GRLELKEDNI ECLLSTACLL QLSQVVEACC KFLMKQLHPS NCLGIRSFAD AQGCTDLHKV AHNYTMEHFM EVIRNQEFVL LPASEIAKLL ASDDMNIPNE ETILNALLTW VRHDLEQRRK DLSKLLAYIR LPLLAPQFLA DMENNVLFRD DIECQKLIME AMKYHLLPER RPMLQSPRTK PRKSTVGTLF AVGGMDSTKG ATSIEKYDLR TNMWTPVANM NGRRLQFGVA VLDDKLYVVG GRDGLKTLNT VECYNPKTKT WSVMPPMSTH RHGLGVAVLE GPMYAVGGHD GWSYLNTVER WDPQARQWNF VATMSTPRST VGVAVLSGKL YAVGGRDGSS CLKSVECFDP HTNKWTLCAQ MSKRRGGVGV TTWNGLLYAI GGHDAPASNL TSRLSDCVER YDPKTDMWTA VASMSISRDA VGVCLLGDKL YAVGGYDGQA YLNTVEAYDP QTNEWTQVAP LCLGRAGACV VTVKL
Genular Protein ID: 1823711082
Symbol: Q59HD9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 593
- Mass: 66256
- Checksum: E5C4CEAD99436207
- Sequence:
AVTHGRLRSP TRTSNSSQTL SSCHTMEPCT SDEFFQALNH AEQTFKKMEN YLRHKQLCDV ILVAGDRRIP AHRLVLSSVS DYFAAMFTND VREARQEEIK MEGVEPNSLW SLIQYAYTGR LELKEDNIEC LLSTACLLQL SQVVEACCKF LMKQLHPSNC LGIRSFADAQ GCTDLHKVAH NYTMEHFMEV IRNQEFVLLP ASEIAKLLAS DDMNIPNEET ILNALLTWVR HDLEQRRKDL SKLLAYIRLP LLAPQFLADM ENNVLFRDDI ECQKLIMEAM KYHLLPERRP MLQSPRTKPR KSTVGTLFAV GGMDSTKGAT SIEKYDLRTN MWTPVANMNG RRLQFGVAVL DDKLYVVGGR DGLKTLNTVE CYNPKTKTWS VMPPMSTHRH GLGVAVLEGP MYAVGGHDGW SYLNTVERWD PQARQWNFVA TMSTPRSTVG VAVLSGKLYA VGGRDGSSCL KSVECFDPHT NKWTLCAQMS KRRGGVGVTT WNGLLYAIGG HDAPASNLTS RLSDCVERYD PKTDMWTAVA SMSISRDAVG VCLLGDKLYA VGGYDGQAYL NTVEAYDPQT NEWTQVAPLC LGRAGACVVT VKL
Genular Protein ID: 2830138671
Symbol: Q7Z6D5_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 762
- Mass: 85029
- Checksum: B520081D12B6E0AB
- Sequence:
CGTPAWPPRP AVTHGRLRSP TRRAYTSLVL VGCTNLCAVL FARCLDDHLV SLRMSGSRKE FDVKQILKIR WRWFGHQASS PNSTVDSQQG EFWNRGQTGA NGGRKFLDPC SLQLPLASIG YRRSSQLDFQ NSPSWPMAST SEVPAFEFTA EDCGGAHWLD RPEVDDGTSE EENESDSSSC RTSNSSQTLS SCHTMEPCTS DEFFQALNHA EQTFKKMENY LRHKQLCDVI LVAGDRRIPA HRLVLSSVSD YFAAMFTNDV REARQEEIKM EGVEPNSLWS LIQYAYTGRL ELKEDNIECL LSTACLLQLS QVVEACCKFL MKQLHPSNCL GIRSFADAQG CTDLHKVAHN YTMEHFMEVI RNQEFVLLPA SEIAKLLASD DMNIPNEETI LNALLTWVRH DLEQRRKDLS KLLAYIRLPL LAPQFLADME NNVLFRDDIE CQKLIMEAMK YHLLPERRPM LQSPRTKPRK STVGTLFAVG GMDSTKGATS IEKYDLRTNM WTPVANMNGR RLQFGVAVLD DKLYVVGGRD GLKTLNTVEC YNPKTKTWSV MPPMSTHRHG LGVAVLEGPM YAVGGHDGWS YLNTVERWDP QARQWNFVAT MSTPRSTVGV AVLSGKLYAV GGRDGSSCLK SVECFDPHTN KWTLCAQMSK RRGGVGVTTW NGLLYAIGGH DAPASNLTSR LSDCVERYDP KTDMWTAVAS MSISRDAVGV CLLGDKLYAV GGYDGQAYLN TVEAYDPQTN EWTQVAPLCL GRAGACVVTV KL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.