Details for: PLCE1

Gene ID: 51196

Symbol: PLCE1

Ensembl ID: ENSG00000138193

Description: phospholipase C epsilon 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 242.5018
    Cell Significance Index: -37.7200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 147.4117
    Cell Significance Index: -37.3900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 30.7716
    Cell Significance Index: -37.9400
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 29.2435
    Cell Significance Index: -27.9200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 13.3340
    Cell Significance Index: -35.7200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 13.0447
    Cell Significance Index: 1896.2000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 9.6350
    Cell Significance Index: -38.0200
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 3.4174
    Cell Significance Index: 31.4700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.8799
    Cell Significance Index: 130.5400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 2.8531
    Cell Significance Index: 148.2100
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 2.5087
    Cell Significance Index: 37.5900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.5910
    Cell Significance Index: 286.8200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.1347
    Cell Significance Index: 215.9400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.0837
    Cell Significance Index: 133.2600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.9549
    Cell Significance Index: 73.2800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.8168
    Cell Significance Index: 1257.4600
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6806
    Cell Significance Index: 614.5500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.6537
    Cell Significance Index: 36.6800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.5458
    Cell Significance Index: 14.0300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.5354
    Cell Significance Index: 10.4500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5246
    Cell Significance Index: 286.4900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.5020
    Cell Significance Index: 347.2300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.4478
    Cell Significance Index: 843.2000
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.4259
    Cell Significance Index: 6.4800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4138
    Cell Significance Index: 67.3000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.3347
    Cell Significance Index: 212.5900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2212
    Cell Significance Index: 43.9000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.2150
    Cell Significance Index: 396.5100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2100
    Cell Significance Index: 20.7700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1763
    Cell Significance Index: 5.0800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.1692
    Cell Significance Index: 230.0000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1513
    Cell Significance Index: 20.7800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1478
    Cell Significance Index: 10.2200
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.1011
    Cell Significance Index: 2.1600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0743
    Cell Significance Index: 3.9000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0691
    Cell Significance Index: 13.8700
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 0.0493
    Cell Significance Index: 0.6900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0484
    Cell Significance Index: 21.4000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0473
    Cell Significance Index: 29.5600
  • Cell Name: glioblast (CL0000030)
    Fold Change: 0.0350
    Cell Significance Index: 0.2200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0288
    Cell Significance Index: 1.3500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0286
    Cell Significance Index: 1.0100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0151
    Cell Significance Index: 5.4100
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0093
    Cell Significance Index: -6.8700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0158
    Cell Significance Index: -2.7000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0268
    Cell Significance Index: -12.1700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0268
    Cell Significance Index: -0.5700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0343
    Cell Significance Index: -19.3400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0407
    Cell Significance Index: -29.8200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0509
    Cell Significance Index: -38.5500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0880
    Cell Significance Index: -10.2500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0995
    Cell Significance Index: -12.7600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1034
    Cell Significance Index: -29.7600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1063
    Cell Significance Index: -12.1800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1148
    Cell Significance Index: -24.1700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1293
    Cell Significance Index: -4.1400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1444
    Cell Significance Index: -3.6100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.1560
    Cell Significance Index: -3.3800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1744
    Cell Significance Index: -22.5400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2121
    Cell Significance Index: -21.6700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2200
    Cell Significance Index: -13.5200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2247
    Cell Significance Index: -4.7700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2377
    Cell Significance Index: -27.1300
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.2416
    Cell Significance Index: -4.8500
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.2756
    Cell Significance Index: -2.1200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2799
    Cell Significance Index: -17.6400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2866
    Cell Significance Index: -20.2700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2884
    Cell Significance Index: -17.6800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2925
    Cell Significance Index: -34.4900
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.3319
    Cell Significance Index: -4.9000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3355
    Cell Significance Index: -34.9400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3680
    Cell Significance Index: -27.4300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.3837
    Cell Significance Index: -5.5000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3950
    Cell Significance Index: -31.2900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.4351
    Cell Significance Index: -28.0700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.4584
    Cell Significance Index: -30.8300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.4739
    Cell Significance Index: -22.2800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.5149
    Cell Significance Index: -26.8200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.5386
    Cell Significance Index: -9.2300
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.5399
    Cell Significance Index: -3.5200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.5439
    Cell Significance Index: -9.1000
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.5444
    Cell Significance Index: -6.8600
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -0.5474
    Cell Significance Index: -3.9800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.5579
    Cell Significance Index: -15.5900
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.5990
    Cell Significance Index: -14.3700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.6564
    Cell Significance Index: -22.8100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.6657
    Cell Significance Index: -17.7800
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.6657
    Cell Significance Index: -10.6800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.6730
    Cell Significance Index: -29.7700
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.6900
    Cell Significance Index: -11.9300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.7082
    Cell Significance Index: -35.7900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.7217
    Cell Significance Index: -14.9700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.7395
    Cell Significance Index: -24.2100
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.7576
    Cell Significance Index: -18.4900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.7838
    Cell Significance Index: -29.6800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.8799
    Cell Significance Index: -30.8300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.8935
    Cell Significance Index: -32.8000
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.9578
    Cell Significance Index: -9.9200
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.9597
    Cell Significance Index: -20.0300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** PLCE1 exhibits the following key characteristics: 1. **Calcium-dependent enzyme**: PLCE1 requires calcium ions to initiate its enzymatic activity, making it a calcium-sensing enzyme. 2. **PIPs hydrolysis**: PLCE1 hydrolyzes PIP2 into DAG and IP3, which are crucial signaling molecules involved in various cellular processes. 3. **Regulation of immune response**: PLCE1 has been implicated in the regulation of immune response, particularly in the activation and differentiation of immune cells. 4. **Cell migration and differentiation**: PLCE1 plays a role in cell migration and differentiation, which are essential processes in immune response and tissue development. 5. **Expression in various cell types**: PLCE1 is expressed in various cell types, including hematopoietic cells, epithelial cells, and immune cells. **Pathways and Functions:** PLCE1 is involved in various signaling pathways, including: 1. **Calcium-mediated signaling**: PLCE1 regulates calcium-dependent signaling pathways, which are essential for immune response, cell migration, and differentiation. 2. **Epidermal growth factor receptor (EGFR) signaling pathway**: PLCE1 has been implicated in the regulation of EGFR signaling pathway, which is involved in cell proliferation, differentiation, and survival. 3. **G-protein coupled receptor (GPCR) signaling pathway**: PLCE1 regulates GPCR signaling pathways, which are involved in various cellular processes, including immune response and cell migration. 4. **Inositol phosphate metabolism**: PLCE1 participates in inositol phosphate metabolism, which is essential for the regulation of cellular signaling pathways. **Clinical Significance:** PLCE1 has been implicated in various diseases, including: 1. **Cancer**: PLCE1 has been identified as a potential biomarker for cancer diagnosis and prognosis. 2. **Autoimmune diseases**: PLCE1 has been implicated in the regulation of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. 3. **Inflammatory disorders**: PLCE1 has been implicated in the regulation of inflammatory disorders, such as asthma and psoriasis. 4. **Neurological disorders**: PLCE1 has been implicated in the regulation of neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, PLCE1 is a key regulator of immune response and cellular signaling. Its dysregulation has been implicated in various diseases, making it a potential target for therapeutic interventions. Further studies are needed to fully understand the role of PLCE1 in human diseases and to explore its potential as a biomarker and therapeutic target.

Genular Protein ID: 41016404

Symbol: PLCE1_HUMAN

Name: Pancreas-enriched phospholipase C

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11022048

Title: Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras.

PubMed ID: 11022048

DOI: 10.1074/jbc.m008324200

PubMed ID: 11022047

Title: A novel bifunctional phospholipase C that is regulated by Galpha 12 and stimulates the Ras/mitogen-activated protein kinase pathway.

PubMed ID: 11022047

DOI: 10.1074/jbc.m008119200

PubMed ID: 10819331

Title: Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10819331

DOI: 10.1093/dnares/7.2.143

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 11395506

Title: Role of the CDC25 homology domain of phospholipase Cepsilon in amplification of Rap1-dependent signaling.

PubMed ID: 11395506

DOI: 10.1074/jbc.m103530200

PubMed ID: 11715024

Title: A new phospholipase-C-calcium signalling pathway mediated by cyclic AMP and a Rap GTPase.

PubMed ID: 11715024

DOI: 10.1038/ncb1101-1020

PubMed ID: 11877431

Title: Stimulation of phospholipase C-epsilon by the M3 muscarinic acetylcholine receptor mediated by cyclic AMP and the GTPase Rap2B.

PubMed ID: 11877431

DOI: 10.1074/jbc.m112024200

PubMed ID: 12444546

Title: Differential roles of Ras and Rap1 in growth factor-dependent activation of phospholipase C epsilon.

PubMed ID: 12444546

DOI: 10.1038/sj.onc.1206003

PubMed ID: 12721365

Title: Activation of CD4 T cells by Raf-independent effectors of Ras.

PubMed ID: 12721365

DOI: 10.1073/pnas.1031494100

PubMed ID: 15157671

Title: Inhibition of phospholipase C-epsilon by Gi-coupled receptors.

PubMed ID: 15157671

DOI: 10.1016/j.cellsig.2004.01.009

PubMed ID: 16293787

Title: Phospholipase C epsilon modulates beta-adrenergic receptor-dependent cardiac contraction and inhibits cardiac hypertrophy.

PubMed ID: 16293787

DOI: 10.1161/01.res.0000196578.15385.bb

PubMed ID: 15558028

Title: Signaling properties and expression in normal and tumor tissues of two phospholipase C epsilon splice variants.

PubMed ID: 15558028

DOI: 10.1038/sj.onc.1208168

PubMed ID: 16537651

Title: The small GTPase R-Ras regulates organization of actin and drives membrane protrusions through the activity of PLCepsilon.

PubMed ID: 16537651

DOI: 10.1242/jcs.02835

PubMed ID: 29058690

Title: Advillin acts upstream of phospholipase C 1 in steroid-resistant nephrotic syndrome.

PubMed ID: 29058690

DOI: 10.1172/jci94138

PubMed ID: 16483931

Title: Structural and mechanistic insights into ras association domains of phospholipase C epsilon.

PubMed ID: 16483931

DOI: 10.1016/j.molcel.2006.01.008

PubMed ID: 17086182

Title: Positional cloning uncovers mutations in PLCE1 responsible for a nephrotic syndrome variant that may be reversible.

PubMed ID: 17086182

DOI: 10.1038/ng1918

PubMed ID: 23595123

Title: A molecular genetic analysis of childhood nephrotic syndrome in a cohort of Saudi Arabian families.

PubMed ID: 23595123

DOI: 10.1038/jhg.2013.27

Sequence Information:

  • Length: 2302
  • Mass: 258715
  • Checksum: 71DDE446277077A3
  • Sequence:
  • MTSEEMTASV LIPVTQRKVV SAQSAADESS EKVSDINISK AHTVRRSGET SHTISQLNKL 
    KEEPSGSNLP KILSIAREKI VSDENSNEKC WEKIMPDSAK NLNINCNNIL RNHQHGLPQR 
    QFYEMYNSVA EEDLCLETGI PSPLERKVFP GIQLELDRPS MGISPLGNQS VIIETGRAHP 
    DSRRAVFHFH YEVDRRMSDT FCTLSENLIL DDCGNCVPLP GGEEKQKKNY VAYTCKLMEL 
    AKNCDNKNEQ LQCDHCDTLN DKYFCFEGSC EKVDMVYSGD SFCRKDFTDS QAAKTFLSHF 
    EDFPDNCDDV EEDAFKSKKE RSTLLVRRFC KNDREVKKSV YTGTRAIVRT LPSGHIGLTA 
    WSYIDQKRNG PLLPCGRVME PPSTVEIRQD GSQRLSEAQW YPIYNAVRRE ETENTVGSLL 
    HFLTKLPASE TAHGRISVGP CLKQCVRDTV CEYRATLQRT SISQYITGSL LEATTSLGAR 
    SGLLSTFGGS TGRMMLKERQ PGPSVANSNA LPSSSAGISK ELIDLQPLIQ FPEEVASILM 
    EQEQTIYRRV LPVDYLCFLT RDLGTPECQS SLPCLKASIS ASILTTQNGE HNALEDLVMR 
    FNEVSSWVTW LILTAGSMEE KREVFSYLVH VAKCCWNMGN YNAVMEFLAG LRSRKVLKMW 
    QFMDQSDIET MRSLKDAMAQ HESSCEYRKV VTRALHIPGC KVVPFCGVFL KELCEVLDGA 
    SGLMKLCPRY NSQEETLEFV ADYSGQDNFL QRVGQNGLKN SEKESTVNSI FQVIRSCNRS 
    LETDEEDSPS EGNSSRKSSL KDKSRWQFII GDLLDSDNDI FEQSKEYDSH GSEDSQKAFD 
    HGTELIPWYV LSIQADVHQF LLQGATVIHY DQDTHLSARC FLQLQPDNST LTWVKPTTAS 
    PASSKAKLGV LNNTAEPGKF PLLGNAGLSS LTEGVLDLFA VKAVYMGHPG IDIHTVCVQN 
    KLGSMFLSET GVTLLYGLQT TDNRLLHFVA PKHTAKMLFS GLLELTRAVR KMRKFPDQRQ 
    QWLRKQYVSL YQEDGRYEGP TLAHAVELFG GRRWSARNPS PGTSAKNAEK PNMQRNNTLG 
    ISTTKKKKKI LMRGESGEVT DDEMATRKAK MHKECRSRSG SDPQDINEQE ESEVNAIANP 
    PNPLPSRRAH SLTTAGSPNL AAGTSSPIRP VSSPVLSSSN KSPSSAWSSS SWHGRIKGGM 
    KGFQSFMVSD SNMSFVEFVE LFKSFSVRSR KDLKDLFDVY AVPCNRSGSE SAPLYTNLTI 
    DENTSDLQPD LDLLTRNVSD LGLFIKSKQQ LSDNQRQISD AIAAASIVTN GTGIESTSLG 
    IFGVGILQLN DFLVNCQGEH CTYDEILSII QKFEPSISMC HQGLMSFEGF ARFLMDKENF 
    ASKNDESQEN IKELQLPLSY YYIESSHNTY LTGHQLKGES SVELYSQVLL QGCRSVELDC 
    WDGDDGMPII YHGHTLTTKI PFKEVVEAID RSAFINSDLP IIISIENHCS LPQQRKMAEI 
    FKTVFGEKLV TKFLFETDFS DDPMLPSPDQ LRKKVLLKNK KLKAHQTPVD ILKQKAHQLA 
    SMQVQAYNGG NANPRPANNE EEEDEEDEYD YDYESLSDDN ILEDRPENKS CNDKLQFEYN 
    EEIPKRIKKA DNSACNKGKV YDMELGEEFY LDQNKKESRQ IAPELSDLVI YCQAVKFPGL 
    STLNASGSSR GKERKSRKSI FGNNPGRMSP GETASFNKTS GKSSCEGIRQ TWEESSSPLN 
    PTTSLSAIIR TPKCYHISSL NENAAKRLCR RYSQKLTQHT ACQLLRTYPA ATRIDSSNPN 
    PLMFWLHGIQ LVALNYQTDD LPLHLNAAMF EANGGCGYVL KPPVLWDKNC PMYQKFSPLE 
    RDLDSMDPAV YSLTIVSGQN VCPSNSMGSP CIEVDVLGMP LDSCHFRTKP IHRNTLNPMW 
    NEQFLFHVHF EDLVFLRFAV VENNSSAVTA QRIIPLKALK RGYRHLQLRN LHNEVLEISS 
    LFINSRRMEE NSSGNTMSAS SMFNTEERKC LQTHRVTVHG VPGPEPFTVF TINGGTKAKQ 
    LLQQILTNEQ DIKPVTTDYF LMEEKYFISK EKNECRKQPF QRAIGPEEEI MQILSSWFPE 
    EGYMGRIVLK TQQENLEEKN IVQDDKEVIL SSEEESFFVQ VHDVSPEQPR TVIKAPRVST 
    AQDVIQQTLC KAKYSYSILS NPNPSDYVLL EEVVKDTTNK KTTTPKSSQR VLLDQECVFQ 
    AQSKWKGAGK FILKLKEQVQ ASREDKKKGI SFASELKKLT KSTKQPRGLT SPSQLLTSES 
    IQTKEEKPVG GLSSSDTMDY RQ

Genular Protein ID: 1463611331

Symbol: B7ZM61_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 2286
  • Mass: 257104
  • Checksum: 8E7D88B28FA21B0C
  • Sequence:
  • MTSEEMTASV LIPVTQRKVV SAQSAADESS EKVSDINISK AHTVRRSGET SHTISQLNKL 
    KEEPSGSNLP KILSIAREKI VSDENSNEKC WEKIMPDSAK NLNINCNNIL RNHQHGLPQR 
    QFYEMYNSVA EEDLCLETGI PSPLERKVFP GIQLELDRPS MGISPLGNQS VIIETGRAHP 
    DSRRAVFHFH YEVDRRMSDT FCTLSENLIL DDCGNCVPLP GGEEKQKKNY VAYTCKLMEL 
    AKNCDNKNEQ LQCDHCDTLN DKYFCFEGSC EKVDMVYSGD SFCRKDFTDS QAAKTFLSHF 
    EDFPDNCDDV EEDAFKSKKE RSTLLVRRFC KNDREVKKSV YTGTRAIVRT LPSGHIGLTA 
    WSYIDQKRNG PLLPCGRVME PPSTVEIRQD GSQRLSEAQW YPIYNAVRRE ETENTVGSLL 
    HFLTKLPASE TAHGRISVGP CLKQCVRDTV CEYRATLQRT SISQYITGSL LEATTSLGAR 
    SGLLSTFGGS TGRMMLKERQ PGPSVANSNA LPSSSAGISK ELIDLQPLIQ FPEEVASILM 
    EQEQTIYRRV LPVDYLCFLT RDLGTPECQS SLPCLKASIS ASILTTQNGE HNALEDLVMR 
    FNEVSSWVTW LILTAGSMEE KREVFSYLVH VAKCCWNMGN YNAVMEFLAG LRSRKVLKMW 
    QFMDQSDIET MRSLKDAMAQ HESSCEYRKV VTRALHIPGC KVVPFCGVFL KELCEVLDGA 
    SGLMKLCPRY NSQEETLEFV ADYSGQDNFL QRVGQNGLKN SEKESTVNSI FQVIRSCNRS 
    LETDEEDSPS EGNSSRKSSL KDKSRWQFII GDLLDSDNDI FEQSKEYDSH GSEDSQKAFD 
    HGTELIPWYV LSIQADVHQF LLQGATVIHY DQDTHLSARC FLQLQPDNST LTWVKPTTAS 
    PASSKAKLGV LNNTAEPGKF PLLGNAGLSS LTEGVLDLFA VKAVYMGHPG IDIHTVCVQN 
    KLGSMFLSET GVTLLYGLQT TDNRLLHFVA PKHTAKMLFS GLLELTRAVR KMRKFPDQRQ 
    QWLRKQYVSL YQEDGRYEGP TLAHAVELFG GRRWSARNPS PGTSAKNAEK PNMQRNNTLG 
    ISTTKKKKKI LMRGESGEVT DDEMATRKAK MHKECRSRSG SDPQDINEQE ESEVNAIANP 
    PNPLPSRRAH SLTTAGSPNL AAGTSSPISA WSSSSWHGRI KGGMKGFQSF MVSDSNMSFV 
    EFVELFKSFS VRSRKDLKDL FDVYAVPCNR SGSESAPLYT NLTIDENTSD LQPDLDLLTR 
    NVSDLGLFIK SKQQLSDNQR QISDAIAAAS IVTNGTGIES TSLGIFGVGI LQLNDFLVNC 
    QGEHCTYDEI LSIIQKFEPS ISMCHQGLMS FEGFARFLMD KENFASKNDE SQENIKELQL 
    PLSYYYIESS HNTYLTGHQL KGESSVELYS QVLLQGCRSV ELDCWDGDDG MPIIYHGHTL 
    TTKIPFKEVV EAIDRSAFIN SDLPIIISIE NHCSLPQQRK MAEIFKTVFG EKLVTKFLFE 
    TDFSDDPMLP SPDQLRKKVL LKNKKLKAHQ TPVDILKQKA HQLASMQVQA YNGGNANPRP 
    ANNEEEEDEE DEYDYDYESL SDDNILEDRP ENKSCNDKLQ FEYNEEIPKR IKKADNSACN 
    KGKVYDMELG EEFYLDQNKK ESRQIAPELS DLVIYCQAVK FPGLSTLNAS GSSRGKERKS 
    RKSIFGNNPG RMSPGETASF NKTSGKSSCE GIRQTWEESS SPLNPTTSLS AIIRTPKCYH 
    ISSLNENAAK RLCRRYSQKL TQHTACQLLR TYPAATRIDS SNPNPLMFWL HGIQLVALNY 
    QTDDLPLHLN AAMFEANGGC GYVLKPPVLW DKNCPMYQKF SPLERDLDSM DPAVYSLTIV 
    SGQNVCPSNS MGSPCIEVDV LGMPLDSCHF RTKPIHRNTL NPMWNEQFLF HVHFEDLVFL 
    RFAVVENNSS AVTAQRIIPL KALKRGYRHL QLRNLHNEVL EISSLFINSR RMEENSSGNT 
    MSASSMFNTE ERKCLQTHRV TVHGVPGPEP FTVFTINGGT KAKQLLQQIL TNEQDIKPVT 
    TDYFLMEEKY FISKEKNECR KQPFQRAIGP EEEIMQILSS WFPEEGYMGR IVLKTQQENL 
    EEKNIVQDDK EVILSSEEES FFVQVHDVSP EQPRTVIKAP RVSTAQDVIQ QTLCKAKYSY 
    SILSNPNPSD YVLLEEVVKD TTNKKTTTPK SSQRVLLDQE CVFQAQSKWK GAGKFILKLK 
    EQVQASREDK KKGISFASEL KKLTKSTKQP RGLTSPSQLL TSESIQTKEE KPVGGLSSSD 
    TMDYRQ

Genular Protein ID: 1401515284

Symbol: A0A8I5KXT2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 1978
  • Mass: 222261
  • Checksum: 76C7FB76CDD26298
  • Sequence:
  • MVSEGSAAGR DFAGMEEVRQ LHVRFCKGIK IWHQAWFLCS LLGREPQERE AGCQLWLCTL 
    SAVLKVGWLF PLSEVPNFTL LKDGCGCWRL KEDQIYNAVR REETENTVGS LLHFLTKLPA 
    SETAHGRISV GPCLKQCVRD TVCEYRATLQ RTSISQYITG SLLEATTSLG ARSGLLSTFG 
    GSTGRMMLKE RQPGPSVANS NALPSSSAGI SKELIDLQPL IQFPEEVASI LMEQEQTIYR 
    RVLPVDYLCF LTRDLGTPEC QSSLPCLKAS ISASILTTQN GEHNALEDLV MRFNEVSSWV 
    TWLILTAGSM EEKREVFSYL VHVAKCCWNM GNYNAVMEFL AGLRSRKVLK MWQFMDQSDI 
    ETMRSLKDAM AQHESSCEYR KVVTRALHIP GCKVVPFCGV FLKELCEVLD GASGLMKLCP 
    RYNSQEETLE FVADYSGQDN FLQRVGQNGL KNSEKESTVN SIFQVIRSCN RSLETDEEDS 
    PSEGNSSRKS SLKDKSRWQF IIGDLLDSDN DIFEQSKEYD SHGSEDSQKA FDHGTELIPW 
    YVLSIQADVH QFLLQGATVI HYDQDTHLSA RCFLQLQPDN STLTWVKPTT ASPASSKAKL 
    GVLNNTAEPG KFPLLGNAGL SSLTEGVLDL FAVKAVYMGH PGIDIHTVCV QNKLGSMFLS 
    ETGVTLLYGL QTTDNRLLHF VAPKHTAKML FSGLLELTRA VRKMRKFPDQ RQQWLRKQYV 
    SLYQEDGRYE GPTLAHAVEL FGGRRWSARN PSPGTSAKNA EKPNMQRNNT LGISTTKKKK 
    KILMRGESGE VTDDEMATRK AKMHKECRSR SGSDPQDINE QEESEVNAIA NPPNPLPSRR 
    AHSLTTAGSP NLAAGTSSPI SAWSSSSWHG RIKGGMKGFQ SFMVSDSNMS FVEFVELFKS 
    FSVRSRKDLK DLFDVYAVPC NRSGSESAPL YTNLTIDENT SDLQPDLDLL TRNVSDLGLF 
    IKSKQQLSDN QRQISDAIAA ASIVTNGTGI ESTSLGIFGV GILQLNDFLV NCQGEHCTYD 
    EILSIIQKFE PSISMCHQGL MSFEGFARFL MDKENFASKN DESQENIKEL QLPLSYYYIE 
    SSHNTYLTGH QLKGESSVEL YSQVLLQGCR SVELDCWDGD DGMPIIYHGH TLTTKIPFKE 
    VVEAIDRSAF INSDLPIIIS IENHCSLPQQ RKMAEIFKTV FGEKLVTKFL FETDFSDDPM 
    LPSPDQLRKK VLLKNKKLKA HQTPVDILKQ KAHQLASMQV QAYNGGNANP RPANNEEEED 
    EEDEYDYDYE SLSDDNILED RPENKSCNDK LQFEYNEEIP KRIKKADNSA CNKGKVYDME 
    LGEEFYLDQN KKESRQIAPE LSDLVIYCQA VKFPGLSTLN ASGSSRGKER KSRKSIFGNN 
    PGRMSPGETA SFNKTSGKSS CEGIRQTWEE SSSPLNPTTS LSAIIRTPKC YHISSLNENA 
    AKRLCRRYSQ KLTQHTACQL LRTYPAATRI DSSNPNPLMF WLHGIQLVAL NYQTDDLPLH 
    LNAAMFEANG GCGYVLKPPV LWDKNCPMYQ KFSPLERDLD SMDPAVYSLT IVSGQNVCPS 
    NSMGSPCIEV DVLGMPLDSC HFRTKPIHRN TLNPMWNEQF LFHVHFEDLV FLRFAVVENN 
    SSAVTAQRII PLKALKRGYR HLQLRNLHNE VLEISSLFIN SRRMEENSSG NTMSASSMFN 
    TEERKCLQTH RVTVHGVPGP EPFTVFTING GTKAKQLLQQ ILTNEQDIKP VTTDYFLMEE 
    KYFISKEKNE CRKQPFQRAI GPEEEIMQIL SSWFPEEGYM GRIVLKTQQE NLEEKNIVQD 
    DKEVILSSEE ESFFVQVHDV SPEQPRTVIK APRVSTAQDV IQQTLCKAKY SYSILSNPNP 
    SDYVLLEEVV KDTTNKKTTT PKSSQRVLLD QECVFQAQSK WKGAGKFILK LKEQVQASRE 
    DKKKGISFAS ELKKLTKSTK QPRGLTSPSQ LLTSESIQTK EEKPVGGLSS SDTMDYRQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.