Details for: GULP1

Gene ID: 51454

Symbol: GULP1

Ensembl ID: ENSG00000144366

Description: GULP PTB domain containing engulfment adaptor 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 346.3301
    Cell Significance Index: -53.8700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 212.8382
    Cell Significance Index: -53.9900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 116.3057
    Cell Significance Index: -47.2500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 49.6312
    Cell Significance Index: -47.3900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 43.7080
    Cell Significance Index: -53.8900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 20.7850
    Cell Significance Index: -55.6800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 13.6744
    Cell Significance Index: -53.9600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 12.1631
    Cell Significance Index: -26.6200
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 6.4102
    Cell Significance Index: 137.0200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 5.5025
    Cell Significance Index: 146.9300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 3.9421
    Cell Significance Index: 221.2100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 3.4892
    Cell Significance Index: 93.5000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 3.4276
    Cell Significance Index: 2176.8800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 2.6495
    Cell Significance Index: 51.7100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.3307
    Cell Significance Index: 4388.5000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.8014
    Cell Significance Index: 79.6800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.6245
    Cell Significance Index: 1123.5800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.6109
    Cell Significance Index: 61.0000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9401
    Cell Significance Index: 848.8500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.9096
    Cell Significance Index: 23.3800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8353
    Cell Significance Index: 135.8600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.7832
    Cell Significance Index: 157.1100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.7610
    Cell Significance Index: 97.5500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.6597
    Cell Significance Index: 236.6400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.6502
    Cell Significance Index: 18.1700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.6324
    Cell Significance Index: 13.7000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5642
    Cell Significance Index: 16.2600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5589
    Cell Significance Index: 55.2900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.5355
    Cell Significance Index: 73.5400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.4528
    Cell Significance Index: 11.3200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.4305
    Cell Significance Index: 20.0700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.3348
    Cell Significance Index: 151.9800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3242
    Cell Significance Index: 35.2600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2865
    Cell Significance Index: 48.9200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2850
    Cell Significance Index: 126.0100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.2812
    Cell Significance Index: 8.0600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2119
    Cell Significance Index: 40.3200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1550
    Cell Significance Index: 84.6600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0909
    Cell Significance Index: 123.6400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.0878
    Cell Significance Index: 5.2700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0745
    Cell Significance Index: 5.1500
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.0683
    Cell Significance Index: 7.8000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0443
    Cell Significance Index: 2.0800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0387
    Cell Significance Index: 1.3600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0174
    Cell Significance Index: -10.8400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0214
    Cell Significance Index: -15.8200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0221
    Cell Significance Index: -2.3000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0282
    Cell Significance Index: -51.9200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0398
    Cell Significance Index: -61.2700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0516
    Cell Significance Index: -37.8300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0618
    Cell Significance Index: -46.7500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0706
    Cell Significance Index: -39.8100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1105
    Cell Significance Index: -5.0100
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.1196
    Cell Significance Index: -1.8200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1352
    Cell Significance Index: -19.6500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.1431
    Cell Significance Index: -25.8000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1438
    Cell Significance Index: -30.2800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1572
    Cell Significance Index: -18.3200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1669
    Cell Significance Index: -48.0300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.1715
    Cell Significance Index: -34.0300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1799
    Cell Significance Index: -3.0100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2263
    Cell Significance Index: -29.2400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2509
    Cell Significance Index: -25.6300
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.2549
    Cell Significance Index: -3.6600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2568
    Cell Significance Index: -29.4200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2739
    Cell Significance Index: -7.4600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.2813
    Cell Significance Index: -34.5900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2872
    Cell Significance Index: -20.3100
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.2892
    Cell Significance Index: -4.1600
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.3277
    Cell Significance Index: -5.0700
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.3906
    Cell Significance Index: -2.3600
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.4415
    Cell Significance Index: -2.6200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.4549
    Cell Significance Index: -27.9600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4799
    Cell Significance Index: -15.3700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.5677
    Cell Significance Index: -42.3100
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.6140
    Cell Significance Index: -4.1600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.6162
    Cell Significance Index: -47.2900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6232
    Cell Significance Index: -49.3600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6298
    Cell Significance Index: -38.6100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.7059
    Cell Significance Index: -47.4700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.7535
    Cell Significance Index: -39.2500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.8860
    Cell Significance Index: -55.8400
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: -1.0054
    Cell Significance Index: -6.2200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.0213
    Cell Significance Index: -53.6200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -1.0410
    Cell Significance Index: -22.1700
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -1.0495
    Cell Significance Index: -7.6300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.0559
    Cell Significance Index: -36.9900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.0778
    Cell Significance Index: -55.9900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -1.0878
    Cell Significance Index: -21.8400
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -1.0996
    Cell Significance Index: -8.4600
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -1.1169
    Cell Significance Index: -23.3100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -1.1626
    Cell Significance Index: -17.5200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -1.2761
    Cell Significance Index: -64.4900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.3307
    Cell Significance Index: -48.8500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.3471
    Cell Significance Index: -46.8100
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -1.3551
    Cell Significance Index: -32.5000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -1.3864
    Cell Significance Index: -29.0200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -1.4071
    Cell Significance Index: -37.0000
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -1.4374
    Cell Significance Index: -20.5900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -1.4773
    Cell Significance Index: -29.2100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Enzyme-like Function:** GULP1 possesses a PTB (phosphotyrosine-binding) domain, which is typically associated with protein-protein interactions and enzymatic activities. This domain enables GULP1 to interact with various proteins, modulating cellular processes. 2. **Cellular Localization:** GULP1 is predominantly expressed in cells involved in immune responses, such as hematopoietic cells, mast cells, and epithelial cells. This localization suggests that GULP1 plays a crucial role in regulating immune cell function and tissue homeostasis. 3. **Protein-Protein Interactions:** GULP1 interacts with various proteins, including those involved in signaling pathways, such as the PI3K/AKT and MAPK/ERK pathways. These interactions modulate cellular processes, including cell survival, proliferation, and differentiation. **Pathways and Functions:** 1. **Apoptotic Process:** GULP1 modulates the apoptotic process by interacting with pro-apoptotic and anti-apoptotic proteins. This interaction influences the balance between cell survival and cell death, ensuring proper tissue homeostasis. 2. **Phagocytosis and Engulfment:** GULP1 is involved in the regulation of phagocytosis and engulfment, processes critical for the removal of pathogens and cellular debris. GULP1 interacts with phagocytic receptors, modulating the engulfment of particles and cells. 3. **Lipid Transport:** GULP1 is involved in lipid transport and metabolism. This function is critical for maintaining cellular membrane structure and function, particularly in cells involved in immune responses. **Clinical Significance:** 1. **Autoimmune Diseases:** Abnormalities in GULP1 expression or function may contribute to autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. Understanding the role of GULP1 in immune cell regulation can provide insights into the development of novel therapeutic strategies. 2. **Cancer:** GULP1 expression is altered in various types of cancer, including leukemia and lymphoma. The dysregulation of GULP1 may contribute to tumorigenesis and cancer progression. 3. **Neurological Disorders:** GULP1 is expressed in the central nervous system, and alterations in GULP1 expression or function may contribute to neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, GULP1 is a multifaceted gene that plays a crucial role in various cellular processes, including apoptosis, phagocytosis, lipid transport, and engulfment. Its expression and function are critical for maintaining immune cell homeostasis and tissue homeostasis. Further research on GULP1 is essential to understand its role in various diseases and to develop novel therapeutic strategies.

Genular Protein ID: 251836541

Symbol: GULP1_HUMAN

Name: PTB domain-containing engulfment adapter protein 1

UniProtKB Accession Codes:

Q9UBP9 B2RB51 B4DQ40 B8ZZ72 D3DPH1 E9PB86 Q53PC1 Q53RF3 Q9BVL3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 2 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 15 Ensembl 8 ExpressionAtlas 1 GO 4 Gene3D 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 RefSeq 4 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10574771

Title: Human CED-6 encodes a functional homologue of the Caenorhabditis elegans engulfment protein CED-6.

PubMed ID: 10574771

DOI: 10.1016/s0960-9822(00)80061-5

PubMed ID: 10574763

Title: The human homologue of Caenorhabditis elegans CED-6 specifically promotes phagocytosis of apoptotic cells.

PubMed ID: 10574763

DOI: 10.1016/s0960-9822(00)80062-7

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10734103

Title: Identification and characterization of a dimerization domain in CED-6, an adapter protein involved in engulfment of apoptotic cells.

PubMed ID: 10734103

DOI: 10.1074/jbc.275.13.9542

PubMed ID: 16497666

Title: The lipoprotein receptor-related protein-1 (LRP) adapter protein GULP mediates trafficking of the LRP ligand prosaposin, leading to sphingolipid and free cholesterol accumulation in late endosomes and impaired efflux.

PubMed ID: 16497666

DOI: 10.1074/jbc.m600621200

PubMed ID: 17205124

Title: Cooperation between engulfment receptors: the case of ABCA1 and MEGF10.

PubMed ID: 17205124

DOI: 10.1371/journal.pone.0000120

PubMed ID: 17398097

Title: Regulation of Arf6 and ACAP1 signaling by the PTB-domain-containing adaptor protein GULP.

PubMed ID: 17398097

DOI: 10.1016/j.cub.2007.03.014

PubMed ID: 17643423

Title: MEGF10 is a mammalian ortholog of CED-1 that interacts with clathrin assembly protein complex 2 medium chain and induces large vacuole formation.

PubMed ID: 17643423

DOI: 10.1016/j.yexcr.2007.06.015

PubMed ID: 18230608

Title: Requirement of adaptor protein GULP during stabilin-2-mediated cell corpse engulfment.

PubMed ID: 18230608

DOI: 10.1074/jbc.m709105200

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

Sequence Information:

  • Length: 304
  • Mass: 34490
  • Checksum: 6FCDE040073DBE8B
  • Sequence:
    • MNRAFSRKKD KTWMHTPEAL SKHFIPYNAK FLGSTEVEQP KGTEVVRDAV RKLKFARHIK 
KSEGQKIPKV ELQISIYGVK ILEPKTKEVQ HNCQLHRISF CADDKTDKRI FTFICKDSES 
NKHLCYVFDS EKCAEEITLT IGQAFDLAYR KFLESGGKDV ETRKQIAGLQ KRIQDLETEN 
MELKNKVQDL ENQLRITQVS APPAGSMTPK SPSTDIFDMI PFSPISHQSS MPTRNGTQPP 
PVPSRSTEIK RDLFGAEPFD PFNCGAADFP PDIQSKLDEM QEGFKMGLTL EGTVFCLDPL 
DSRC

Genular Protein ID: 2744367040

Symbol: H7BZV7_HUMAN

Name: N/A

UniProtKB Accession Codes:

H7BZV7

Database IDs:

Antibodypedia 1 Bgee 1 CDD 2 CTD 1 ChiTaRS 1 EMBL 6 Ensembl 2 ExpressionAtlas 1 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 PANTHER 2 PROSITE 2 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 6 SAM 2 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

Sequence Information:

  • Length: 379
  • Mass: 42684
  • Checksum: 337F766255D1AE70
  • Sequence:
    • MNRAFSRKKD KTWMHTPEAL SKHFIPYNAK FLGSTEVEQP KGTEVVRDAV RKLKFARHIK 
KSEGQKIPKV ELQISIYGVK ILEPKTKEVQ HNCQLHRISF CADDKTDKRI FTFICKDSES 
NKHLCYVFDS EKCAEEITLT IGQAFDLAYR KFLESGGKDV ETRKQIAGLQ KRIQDLETEN 
MELKNKVQDL ENQLRITQVS APPLLHNMSD HEQHVFQRCS SSFWRSNGDS SPCLNISSIS 
VTPINSPDSR LSLGLLIPPP SKCGFPKPVS ESSIPRPHAG SMTPKSPSTD IFDMIPFSPI 
SHQSSMPTRN GTQPPPVPSR STEIKRDLFG AEPFDPFNCG AADFPPDIQS KLDEMQEGFK 
MGLTLEGTVF CLDPLDSRC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.