Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 448.9691
Cell Significance Index: -69.8400 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 244.7925
Cell Significance Index: -62.0900 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 174.5385
Cell Significance Index: -70.9100 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 156.3153
Cell Significance Index: -73.8000 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 150.9569
Cell Significance Index: -77.6500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 75.0359
Cell Significance Index: -71.6400 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 56.5268
Cell Significance Index: -69.7000 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 22.2207
Cell Significance Index: -68.2500 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 18.9803
Cell Significance Index: -41.5400 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 18.1929
Cell Significance Index: -71.7900 - Cell Name: hepatic pit cell (CL2000054)
Fold Change: 7.0421
Cell Significance Index: 18.8700 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 6.2065
Cell Significance Index: 73.9900 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 5.9233
Cell Significance Index: 173.9600 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.4489
Cell Significance Index: 491.2400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 2.3530
Cell Significance Index: 144.6300 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 2.3438
Cell Significance Index: 56.2100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.1484
Cell Significance Index: 770.5800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 2.0508
Cell Significance Index: 115.0800 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.8891
Cell Significance Index: 1306.5700 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 1.8797
Cell Significance Index: 118.4700 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 1.8713
Cell Significance Index: 82.7700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 1.7419
Cell Significance Index: 65.9600 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 1.6905
Cell Significance Index: 199.3600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.4540
Cell Significance Index: 288.5600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 1.0062
Cell Significance Index: 74.9900 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.9481
Cell Significance Index: 20.7600 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.8470
Cell Significance Index: 23.6700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.8287
Cell Significance Index: 113.8100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.7150
Cell Significance Index: 48.0800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6699
Cell Significance Index: 604.8700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.5411
Cell Significance Index: 34.9100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4717
Cell Significance Index: 46.6600 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.4520
Cell Significance Index: 52.6700 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3843
Cell Significance Index: 209.8600 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3154
Cell Significance Index: 51.2900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.2830
Cell Significance Index: 4.8500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1274
Cell Significance Index: 239.9300 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.1002
Cell Significance Index: 10.9000 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0895
Cell Significance Index: 16.1300 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0687
Cell Significance Index: 30.3900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0432
Cell Significance Index: 5.3100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0227
Cell Significance Index: 30.8500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0178
Cell Significance Index: 27.4700 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0066
Cell Significance Index: 3.0000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0063
Cell Significance Index: 3.9700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0014
Cell Significance Index: -2.5300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: -0.0337
Cell Significance Index: -6.4200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0434
Cell Significance Index: -1.2500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0556
Cell Significance Index: -4.2600 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0627
Cell Significance Index: -1.7900 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0732
Cell Significance Index: -55.3700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0750
Cell Significance Index: -55.5800 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0817
Cell Significance Index: -59.9000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1175
Cell Significance Index: -17.0800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1231
Cell Significance Index: -69.4200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1285
Cell Significance Index: -80.2400 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1505
Cell Significance Index: -19.4500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1605
Cell Significance Index: -16.3900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1910
Cell Significance Index: -6.7100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.2115
Cell Significance Index: -36.1200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2242
Cell Significance Index: -64.5200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.2393
Cell Significance Index: -6.3900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.2436
Cell Significance Index: -12.7900 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.2550
Cell Significance Index: -15.3100 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.2977
Cell Significance Index: -38.1600 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.3369
Cell Significance Index: -23.3000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.3457
Cell Significance Index: -15.6700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.3650
Cell Significance Index: -76.8800 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.3770
Cell Significance Index: -9.6300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.4223
Cell Significance Index: -19.8500 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.4482
Cell Significance Index: -9.7100 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.5109
Cell Significance Index: -26.6100 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.5265
Cell Significance Index: -24.5500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.5990
Cell Significance Index: -68.6300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.6151
Cell Significance Index: -19.7000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.6506
Cell Significance Index: -67.7400 - Cell Name: decidual cell (CL2000002)
Fold Change: -0.6545
Cell Significance Index: -10.5000 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.6871
Cell Significance Index: -11.5000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.7935
Cell Significance Index: -56.1200 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.8015
Cell Significance Index: -21.4400 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: -0.9235
Cell Significance Index: -9.6200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.9293
Cell Significance Index: -73.6000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.9556
Cell Significance Index: -58.5900 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.9709
Cell Significance Index: -18.9500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -1.0012
Cell Significance Index: -52.0100 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.0434
Cell Significance Index: -33.2300 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -1.0614
Cell Significance Index: -34.7500 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -1.1412
Cell Significance Index: -22.5700 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -1.1746
Cell Significance Index: -24.9300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -1.2250
Cell Significance Index: -26.0900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -1.2766
Cell Significance Index: -44.3600 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -1.2949
Cell Significance Index: -22.3200 - Cell Name: granulosa cell (CL0000501)
Fold Change: -1.3090
Cell Significance Index: -34.4200 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -1.3885
Cell Significance Index: -19.8900 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -1.4986
Cell Significance Index: -52.5000 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -1.5321
Cell Significance Index: -43.9200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -1.6386
Cell Significance Index: -40.9600 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -1.6751
Cell Significance Index: -33.6300 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -1.6952
Cell Significance Index: -42.2900 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -1.7026
Cell Significance Index: -25.1300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2769900050
Symbol: EVL_HUMAN
Name: Ena/VASP-like protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10931946
Title: Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning.
PubMed ID: 10931946
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 12508121
Title: The DNA sequence and analysis of human chromosome 14.
PubMed ID: 12508121
DOI: 10.1038/nature01348
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 10747096
Title: Fyn-binding protein (Fyb)/SLP-76-associated protein (SLAP), Ena/vasodilator-stimulated phosphoprotein (VASP) proteins and the Arp2/3 complex link T cell receptor (TCR) signaling to the actin cytoskeleton.
PubMed ID: 10747096
PubMed ID: 19367720
Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.
PubMed ID: 19367720
DOI: 10.1021/pr800500r
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 10993894
Title: The orthologous human and murine semaphorin 6A-1 proteins (SEMA6A-1/Sema6A-1) bind to the enabled/vasodilator-stimulated phosphoprotein-like protein (EVL) via a novel carboxyl-terminal zyxin-like domain.
PubMed ID: 10993894
PubMed ID: 15469845
Title: Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics.
PubMed ID: 15469845
PubMed ID: 18158903
Title: Tes, a specific Mena interacting partner, breaks the rules for EVH1 binding.
PubMed ID: 18158903
PubMed ID: 28882895
Title: Peptide array based screening reveals a large number of proteins interacting with the ankyrin repeat domain of the zDHHC17 S-acyltransferase.
PubMed ID: 28882895
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 416
- Mass: 44620
- Checksum: AD5B67458755D659
- Sequence:
MSEQSICQAR ASVMVYDDTS KKWVPIKPGQ QGFSRINIYH NTASNTFRVV GVKLQDQQVV INYSIVKGLK YNQATPTFHQ WRDARQVYGL NFASKEEATT FSNAMLFALN IMNSQEGGPS SQRQVQNGPS PDEMDIQRRQ VMEQHQQQRQ ESLERRTSAT GPILPPGHPS SAASAPVSCS GPPPPPPPPV PPPPTGATPP PPPPLPAGGA QGSSHDESSM SGLAAAIAGA KLRRVQRPED ASGGSSPSGT SKSDANRASS GGGGGGLMEE MNKLLAKRRK AASQSDKPAE KKEDESQMED PSTSPSPGTR AASQPPNSSE AGRKPWERSN SVEKPVSSIL SRTPSVAKSP EAKSPLQSQP HSRMKPAGSV NDMALDAFDL DRMKQEILEE VVRELHKVKE EIIDAIRQEL SGISTT
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.