Details for: HACD3
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 147.1651
Cell Significance Index: -69.4800 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 136.8099
Cell Significance Index: -55.5800 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 58.2984
Cell Significance Index: -55.6600 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 23.9150
Cell Significance Index: -64.0700 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 15.2827
Cell Significance Index: -46.9400 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 10.1298
Cell Significance Index: -22.1700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 3.9275
Cell Significance Index: 204.0200 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 3.1371
Cell Significance Index: 310.3300 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 3.0923
Cell Significance Index: 107.4600 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 2.9418
Cell Significance Index: 27.0900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 2.3185
Cell Significance Index: 130.1000 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 2.0089
Cell Significance Index: 362.1400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.8630
Cell Significance Index: 373.7100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.7506
Cell Significance Index: 347.4100 - Cell Name: granulosa cell (CL0000501)
Fold Change: 1.6224
Cell Significance Index: 42.6600 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 1.6085
Cell Significance Index: 84.4500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.5652
Cell Significance Index: 561.4200 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.4753
Cell Significance Index: 88.5700 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.4679
Cell Significance Index: 801.6600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 1.4048
Cell Significance Index: 172.7300 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 1.2635
Cell Significance Index: 173.5100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.9704
Cell Significance Index: 27.1200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.9572
Cell Significance Index: 60.3300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.9375
Cell Significance Index: 648.4200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.8143
Cell Significance Index: 11.1100 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.8119
Cell Significance Index: 17.5900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.7279
Cell Significance Index: 50.3400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.7206
Cell Significance Index: 33.6000 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.7181
Cell Significance Index: 92.0600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.5936
Cell Significance Index: 44.2400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.5579
Cell Significance Index: 246.6500 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: 0.5351
Cell Significance Index: 11.2000 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.5174
Cell Significance Index: 11.3300 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.5025
Cell Significance Index: 33.7900 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.4762
Cell Significance Index: 29.2700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.3519
Cell Significance Index: 10.1400 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3434
Cell Significance Index: 55.8600 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.3405
Cell Significance Index: 24.0900 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.2743
Cell Significance Index: 3.2700 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 0.1217
Cell Significance Index: 6.1500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1202
Cell Significance Index: 226.3900 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1201
Cell Significance Index: 22.8500 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.1125
Cell Significance Index: 5.1000 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0934
Cell Significance Index: 68.5100 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.0933
Cell Significance Index: 0.7400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0358
Cell Significance Index: 55.1800 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0308
Cell Significance Index: 3.9700 - Cell Name: lens fiber cell (CL0011004)
Fold Change: 0.0262
Cell Significance Index: 0.8300 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0192
Cell Significance Index: 26.1500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0146
Cell Significance Index: 0.3900 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0117
Cell Significance Index: 21.5800 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0053
Cell Significance Index: 0.0900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0044
Cell Significance Index: -2.7800 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0179
Cell Significance Index: -0.3000 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0179
Cell Significance Index: -0.8400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0180
Cell Significance Index: -13.6300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0286
Cell Significance Index: -4.8900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0401
Cell Significance Index: -1.4100 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.0492
Cell Significance Index: -1.1800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0608
Cell Significance Index: -27.5900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0657
Cell Significance Index: -48.6400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.1072
Cell Significance Index: -60.4400 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1078
Cell Significance Index: -11.0100 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1094
Cell Significance Index: -2.3300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1106
Cell Significance Index: -3.0100 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1200
Cell Significance Index: -14.1500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1203
Cell Significance Index: -9.2300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1253
Cell Significance Index: -14.3500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.1337
Cell Significance Index: -83.5100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1732
Cell Significance Index: -20.1900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.1786
Cell Significance Index: -7.9000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1987
Cell Significance Index: -57.1600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2031
Cell Significance Index: -10.5800 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.2047
Cell Significance Index: -2.3300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.2106
Cell Significance Index: -30.6200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.2659
Cell Significance Index: -10.0700 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.3210
Cell Significance Index: -3.4900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.3396
Cell Significance Index: -21.9100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.3409
Cell Significance Index: -71.8000 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.3818
Cell Significance Index: -4.8900 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.5787
Cell Significance Index: -60.2600 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: -0.5916
Cell Significance Index: -3.6600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.7385
Cell Significance Index: -58.4900 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.7793
Cell Significance Index: -22.2400 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.7877
Cell Significance Index: -23.2000 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.8087
Cell Significance Index: -33.1400 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.8165
Cell Significance Index: -20.8600 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.9065
Cell Significance Index: -19.2400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.9095
Cell Significance Index: -29.1300 - Cell Name: peg cell (CL4033014)
Fold Change: -0.9691
Cell Significance Index: -22.3900 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.9867
Cell Significance Index: -19.8100 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.9893
Cell Significance Index: -25.4300 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.9905
Cell Significance Index: -29.0900 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -1.1158
Cell Significance Index: -68.4100 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -1.1566
Cell Significance Index: -22.8700 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.2497
Cell Significance Index: -39.8000 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -1.2599
Cell Significance Index: -41.2500 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: -1.2769
Cell Significance Index: -10.5400 - Cell Name: glioblast (CL0000030)
Fold Change: -1.2851
Cell Significance Index: -8.0700 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -1.3933
Cell Significance Index: -23.4700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1987502637
Symbol: HACD3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10747961
Title: B-ind1, a novel mediator of Rac1 signaling cloned from sodium butyrate-treated fibroblasts.
PubMed ID: 10747961
PubMed ID: 11042152
Title: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.
PubMed ID: 11042152
DOI: 10.1101/gr.140200
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 16516406
Title: Human B-ind1 gene promoter: cloning and regulation by histone deacetylase inhibitors.
PubMed ID: 16516406
PubMed ID: 16638134
Title: SSeCKS/Gravin/AKAP12 attenuates expression of proliferative and angiogenic genes during suppression of v-Src-induced oncogenesis.
PubMed ID: 16638134
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18554506
Title: Characterization of four mammalian 3-hydroxyacyl-CoA dehydratases involved in very long-chain fatty acid synthesis.
PubMed ID: 18554506
PubMed ID: 18220336
Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.
PubMed ID: 18220336
DOI: 10.1021/pr0705441
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 18318008
Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.
PubMed ID: 18318008
PubMed ID: 19369195
Title: Large-scale proteomics analysis of the human kinome.
PubMed ID: 19369195
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25687571
Title: The last enzyme of the de novo purine synthesis pathway 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (ATIC) plays a central role in insulin signaling and the Golgi/endosomes protein network.
PubMed ID: 25687571
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 362
- Mass: 43160
- Checksum: 1B3591E88DD85D16
- Sequence:
MENQVLTPHV YWAQRHRELY LRVELSDVQN PAISITENVL HFKAQGHGAK GDNVYEFHLE FLDLVKPEPV YKLTQRQVNI TVQKKVSQWW ERLTKQEKRP LFLAPDFDRW LDESDAEMEL RAKEEERLNK LRLESEGSPE TLTNLRKGYL FMYNLVQFLG FSWIFVNLTV RFCILGKESF YDTFHTVADM MYFCQMLAVV ETINAAIGVT TSPVLPSLIQ LLGRNFILFI IFGTMEEMQN KAVVFFVFYL WSAIEIFRYS FYMLTCIDMD WKVLTWLRYT LWIPLYPLGC LAEAVSVIQS IPIFNETGRF SFTLPYPVKI KVRFSFFLQI YLIMIFLGLY INFRHLYKQR RRRYGQKKKK IH
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.