Details for: NCKIPSD
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 86.0200
Cell Significance Index: -13.3800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 53.5003
Cell Significance Index: -13.5700 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 29.7592
Cell Significance Index: -14.0500 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 28.0857
Cell Significance Index: -11.4100 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 11.9928
Cell Significance Index: -11.4500 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 11.1034
Cell Significance Index: -13.6900 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 4.7371
Cell Significance Index: -12.6900 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 3.5073
Cell Significance Index: -13.8400 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 2.5633
Cell Significance Index: -5.6100 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: 1.4843
Cell Significance Index: 24.4600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.9078
Cell Significance Index: 89.8100 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.9028
Cell Significance Index: 146.8300 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.8285
Cell Significance Index: 22.2000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.7711
Cell Significance Index: 89.8600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.7092
Cell Significance Index: 640.3700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.6727
Cell Significance Index: 134.9400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.6047
Cell Significance Index: 36.3000 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.5751
Cell Significance Index: 62.5600 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.5432
Cell Significance Index: 8.7200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.4145
Cell Significance Index: 8.9800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.3457
Cell Significance Index: 9.9600 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.3446
Cell Significance Index: 17.9500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2840
Cell Significance Index: 19.6400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.2817
Cell Significance Index: 101.0300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.2791
Cell Significance Index: 55.3900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.2074
Cell Significance Index: 9.4000 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1369
Cell Significance Index: 94.6900 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.1139
Cell Significance Index: 2.5000 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.1093
Cell Significance Index: 59.7000 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.0858
Cell Significance Index: 1.1700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0788
Cell Significance Index: 1.9700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0771
Cell Significance Index: 10.5900 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.0711
Cell Significance Index: 1.5200 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.0662
Cell Significance Index: 4.4500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0652
Cell Significance Index: 3.0400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0558
Cell Significance Index: 10.0500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0513
Cell Significance Index: 9.7600 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.0506
Cell Significance Index: 2.6300 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0497
Cell Significance Index: 21.9900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.0421
Cell Significance Index: 2.2100 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0400
Cell Significance Index: 5.1300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0259
Cell Significance Index: 1.9900 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0258
Cell Significance Index: 0.5500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0219
Cell Significance Index: 2.6900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.0170
Cell Significance Index: 1.0700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0168
Cell Significance Index: 30.9700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0150
Cell Significance Index: 23.0300 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.0147
Cell Significance Index: 0.2100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0131
Cell Significance Index: 24.6000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0035
Cell Significance Index: 1.5800 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0010
Cell Significance Index: -1.3600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0023
Cell Significance Index: -0.0800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0037
Cell Significance Index: -0.1000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0043
Cell Significance Index: -2.7000 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0069
Cell Significance Index: -0.8100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0137
Cell Significance Index: -10.0400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0152
Cell Significance Index: -11.2600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0153
Cell Significance Index: -11.5500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0166
Cell Significance Index: -2.4200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0219
Cell Significance Index: -12.3500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0225
Cell Significance Index: -2.3000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0237
Cell Significance Index: -14.8100 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0294
Cell Significance Index: -0.8400 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0334
Cell Significance Index: -5.7000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0393
Cell Significance Index: -11.3200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0499
Cell Significance Index: -5.7200 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0512
Cell Significance Index: -1.6400 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0558
Cell Significance Index: -7.2100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0583
Cell Significance Index: -1.6300 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0597
Cell Significance Index: -2.2600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0630
Cell Significance Index: -3.8700 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0635
Cell Significance Index: -2.8100 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.0650
Cell Significance Index: -1.7100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0683
Cell Significance Index: -14.3900 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0841
Cell Significance Index: -5.9500 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1082
Cell Significance Index: -2.9500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1179
Cell Significance Index: -12.2800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1201
Cell Significance Index: -8.9500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1211
Cell Significance Index: -5.6900 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.1255
Cell Significance Index: -1.8800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1258
Cell Significance Index: -7.0600 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.1391
Cell Significance Index: -1.7300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1484
Cell Significance Index: -11.7500 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1649
Cell Significance Index: -3.5000 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.1689
Cell Significance Index: -4.9600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1702
Cell Significance Index: -10.9800 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1807
Cell Significance Index: -3.7500 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.1837
Cell Significance Index: -9.2800 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1974
Cell Significance Index: -6.8600 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.2115
Cell Significance Index: -1.7300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.2256
Cell Significance Index: -13.8300 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: -0.2282
Cell Significance Index: -1.9400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.2342
Cell Significance Index: -7.4600 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.2436
Cell Significance Index: -4.1800 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.2482
Cell Significance Index: -3.7400 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.2539
Cell Significance Index: -6.0900 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2550
Cell Significance Index: -8.3500 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.2642
Cell Significance Index: -3.8000 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.2649
Cell Significance Index: -9.2800 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.2709
Cell Significance Index: -4.0000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1162573211
Symbol: SPN90_HUMAN
Name: NCK-interacting protein with SH3 domain
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10648423
Title: Novel SH3 protein encoded by the AF3p21 gene is fused to the mixed lineage leukemia protein in a therapy-related leukemia with t(3;11)(p21;q23).
PubMed ID: 10648423
PubMed ID: 10619843
Title: The VacA toxin of Helicobacter pylori identifies a new intermediate filament-interacting protein.
PubMed ID: 10619843
PubMed ID: 11241789
Title: Genomic organization, tissue expression and cellular localization of AF3p21, a fusion partner of MLL in therapy-related leukemia.
PubMed ID: 11241789
DOI: 10.1002/gcc.1102
PubMed ID: 11278500
Title: SPIN90 (SH3 protein interacting with Nck, 90 kDa), an adapter protein that is developmentally regulated during cardiac myocyte differentiation.
PubMed ID: 11278500
PubMed ID: 11509578
Title: mDia-interacting protein acts downstream of rho-mDia and modifies src activation and stress fiber formation.
PubMed ID: 11509578
PubMed ID: 15095401
Title: Identification of FHOD1-binding proteins and mechanisms of FHOD1-regulated actin dynamics.
PubMed ID: 15095401
DOI: 10.1002/jcb.20031
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 18088087
PubMed ID: 19807924
Title: Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening.
PubMed ID: 19807924
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22419821
Title: Identification of IGPR-1 as a novel adhesion molecule involved in angiogenesis.
PubMed ID: 22419821
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 722
- Mass: 78960
- Checksum: 7683046B94647332
- Sequence:
MYRALYAFRS AEPNALAFAA GETFLVLERS SAHWWLAARA RSGETGYVPP AYLRRLQGLE QDVLQAIDRA IEAVHNTAMR DGGKYSLEQR GVLQKLIHHR KETLSRRGPS ASSVAVMTSS TSDHHLDAAA ARQPNGVCRA GFERQHSLPS SEHLGADGGL YQIPLPSSQI PPQPRRAAPT TPPPPVKRRD REALMASGSG GHNTMPSGGN SVSSGSSVSS TSLDTLYTSS SPSEPGSSCS PTPPPVPRRG THTTVSQVQP PPSKASAPEP PAEEEVATGT TSASDDLEAL GTLSLGTTEE KAAAEAAVPR TIGAELMELV RRNTGLSHEL CRVAIGIIVG HIQASVPASS PVMEQVLLSL VEGKDLSMAL PSGQVCHDQQ RLEVIFADLA RRKDDAQQRS WALYEDEGVI RCYLEELLHI LTDADPEVCK KMCKRNEFES VLALVAYYQM EHRASLRLLL LKCFGAMCSL DAAIISTLVS SVLPVELARD MQTDTQDHQK LCYSALILAM VFSMGEAVPY AHYEHLGTPF AQFLLNIVED GLPLDTTEQL PDLCVNLLLA LNLHLPAADQ NVIMAALSKH ANVKIFSEKL LLLLNRGDDP VRIFKHEPQP PHSVLKFLQD VFGSPATAAI FYHTDMMALI DITVRHIADL SPGDKLRMEY LSLMHAIVRT TPYLQHRHRL PDLQAILRRI LNEEETSPQC QMDRMIVREM CKEFLVLGEA PS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.