Details for: ENPP2

Gene ID: 5168

Symbol: ENPP2

Ensembl ID: ENSG00000136960

Description: ectonucleotide pyrophosphatase/phosphodiesterase 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 150.5671
    Cell Significance Index: -23.4200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 90.8756
    Cell Significance Index: -23.0500
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 50.4360
    Cell Significance Index: -20.4900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 49.7805
    Cell Significance Index: -23.5000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 18.9950
    Cell Significance Index: -23.4200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 6.3129
    Cell Significance Index: 387.0400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 6.0267
    Cell Significance Index: -13.1900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.8692
    Cell Significance Index: -23.1600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 5.5526
    Cell Significance Index: 177.8400
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 3.5713
    Cell Significance Index: 22.1000
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 3.1710
    Cell Significance Index: 67.7800
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 2.9260
    Cell Significance Index: 23.8600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.8042
    Cell Significance Index: 127.1100
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 2.3329
    Cell Significance Index: 41.2300
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 1.6689
    Cell Significance Index: 10.4500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.4898
    Cell Significance Index: 77.6000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 1.3812
    Cell Significance Index: 28.9100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.3506
    Cell Significance Index: 36.1900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.3273
    Cell Significance Index: 842.9500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.2976
    Cell Significance Index: 188.6200
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 1.2907
    Cell Significance Index: 19.4500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.2158
    Cell Significance Index: 120.2700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.1165
    Cell Significance Index: 67.0300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8837
    Cell Significance Index: 96.1200
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.8629
    Cell Significance Index: 13.3500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7715
    Cell Significance Index: 153.1000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.7321
    Cell Significance Index: 15.8600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.7138
    Cell Significance Index: 91.5100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6241
    Cell Significance Index: 563.5400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.5805
    Cell Significance Index: 11.3300
  • Cell Name: embryonic fibroblast (CL2000042)
    Fold Change: 0.5414
    Cell Significance Index: 2.5900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.4109
    Cell Significance Index: 147.4000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3504
    Cell Significance Index: 10.1000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2689
    Cell Significance Index: 51.1700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1308
    Cell Significance Index: 90.4600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0991
    Cell Significance Index: 2.1100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0776
    Cell Significance Index: 15.5700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0377
    Cell Significance Index: 70.9300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0088
    Cell Significance Index: 0.3100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0014
    Cell Significance Index: -1.0200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0015
    Cell Significance Index: -0.9300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0046
    Cell Significance Index: -8.4400
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.0065
    Cell Significance Index: -0.0700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0075
    Cell Significance Index: -1.0300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0141
    Cell Significance Index: -21.7500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0149
    Cell Significance Index: -8.1300
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.0191
    Cell Significance Index: -0.2400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0202
    Cell Significance Index: -27.5100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0216
    Cell Significance Index: -12.2000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0293
    Cell Significance Index: -21.4900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0313
    Cell Significance Index: -23.6700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0316
    Cell Significance Index: -6.6500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0394
    Cell Significance Index: -17.8700
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: -0.0418
    Cell Significance Index: -0.3000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0497
    Cell Significance Index: -1.4300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0645
    Cell Significance Index: -18.5700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0691
    Cell Significance Index: -7.8900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0716
    Cell Significance Index: -12.9100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0744
    Cell Significance Index: -12.7100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0870
    Cell Significance Index: -8.8900
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.1055
    Cell Significance Index: -2.6300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1150
    Cell Significance Index: -1.9300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1409
    Cell Significance Index: -17.3300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1706
    Cell Significance Index: -22.0500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1912
    Cell Significance Index: -21.9000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2072
    Cell Significance Index: -24.1500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2088
    Cell Significance Index: -21.7400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2167
    Cell Significance Index: -12.1600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2186
    Cell Significance Index: -25.7800
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.2277
    Cell Significance Index: -9.9000
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: -0.2278
    Cell Significance Index: -2.4500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2512
    Cell Significance Index: -16.8900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2753
    Cell Significance Index: -21.8000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2819
    Cell Significance Index: -17.3300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2994
    Cell Significance Index: -22.3200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3012
    Cell Significance Index: -15.2200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.3090
    Cell Significance Index: -23.7100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3130
    Cell Significance Index: -19.7300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.3267
    Cell Significance Index: -9.1300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3392
    Cell Significance Index: -15.9400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3684
    Cell Significance Index: -23.7700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3850
    Cell Significance Index: -17.0300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4129
    Cell Significance Index: -21.6800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.4831
    Cell Significance Index: -18.3000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.5043
    Cell Significance Index: -13.4900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.5117
    Cell Significance Index: -26.5800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.5632
    Cell Significance Index: -19.7300
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.5729
    Cell Significance Index: -8.1400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.5763
    Cell Significance Index: -26.8700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.6003
    Cell Significance Index: -15.4300
  • Cell Name: melanocyte (CL0000148)
    Fold Change: -0.6008
    Cell Significance Index: -5.6300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.6104
    Cell Significance Index: -17.9800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.6206
    Cell Significance Index: -17.7100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.6277
    Cell Significance Index: -16.7600
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.6338
    Cell Significance Index: -10.6600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.6381
    Cell Significance Index: -20.8900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.6414
    Cell Significance Index: -22.2900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.6631
    Cell Significance Index: -21.1200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.6948
    Cell Significance Index: -18.2700
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.7167
    Cell Significance Index: -26.3100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ENPP2 is a transmembrane enzyme that exhibits both ectonucleotidase and phosphodiesterase activities. Its ectonucleotidase activity involves the degradation of extracellular nucleotides, while its phosphodiesterase activity involves the hydrolysis of phosphodiester bonds. ENPP2 is expressed in various cell types, including oligodendrocytes, endothelial cells, and immune cells. Its expression is often regulated by inflammatory cytokines and growth factors, indicating its involvement in immune responses. **Pathways and Functions:** ENPP2 has been implicated in several signaling pathways, including: 1. **Immune Response:** ENPP2 regulates the activity of immune cells, such as T cells and dendritic cells, by modulating the levels of extracellular nucleotides and phosphodiesterase products. 2. **Cell Migration:** ENPP2 is involved in the regulation of cell migration, particularly in the context of immune cell migration and angiogenesis. 3. **Metabolism:** ENPP2 plays a role in the metabolism of vitamins and cofactors, including vitamin B5 (pantothenate). 4. **Signaling Pathways:** ENPP2 interacts with various signaling molecules, including G-proteins, kinases, and phosphatases, to modulate their activity. **Clinical Significance:** Dysregulation of ENPP2 has been implicated in various immune-related disorders, including: 1. **Autoimmune Diseases:** ENPP2 has been linked to autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis, where it contributes to the regulation of immune cell activity. 2. **Cancer:** ENPP2 has been implicated in cancer progression, particularly in the context of tumor cell migration and invasion. 3. **Neurological Disorders:** ENPP2 has been linked to neurological disorders, such as Alzheimer's disease and Parkinson's disease, where it contributes to the regulation of neuronal function and survival. In conclusion, ENPP2 is a multifunctional enzyme that plays a crucial role in various cellular processes, including immune response, cell migration, and metabolism. Its dysregulation has been implicated in various immune-related disorders, highlighting the importance of ENPP2 in maintaining immune homeostasis and overall health. **Future Directions:** Further research is needed to fully elucidate the mechanisms by which ENPP2 regulates immune responses and cellular migration. Potential therapeutic strategies targeting ENPP2 may include the development of small molecule inhibitors or antibody-based therapies to modulate its activity in immune-related disorders.

Genular Protein ID: 3152795210

Symbol: ENPP2_HUMAN

Name: Extracellular lysophospholipase D

UniProtKB Accession Codes:

Q13822 A8UHA1 E9PHP7 Q13827 Q14555 Q15117 Q9UCQ8 Q9UCR0 Q9UCR1 Q9UCR2 Q9UCR3 Q9UCR4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 2 CTD 1 ChEBI 100 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugCentral 1 EC 3 EMBL 8 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 22 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 9 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 RNAct 1 Reactome 1 RefSeq 3 Rhea 49 SABIO-RK 1 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissLipids 2 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7982964

Title: cDNA cloning of the human tumor motility-stimulating protein, autotaxin, reveals a homology with phosphodiesterases.

PubMed ID: 7982964

DOI: 10.1016/s0021-9258(18)43838-0

PubMed ID: 8586446

Title: Molecular cloning and chromosomal assignment of the human brain-type phosphodiesterase I/nucleotide pyrophosphatase gene (PDNP2).

PubMed ID: 8586446

DOI: 10.1006/geno.1995.0036

PubMed ID: 8579579

Title: Cloning, chromosomal localization, and tissue expression of autotaxin from human teratocarcinoma cells.

PubMed ID: 8579579

DOI: 10.1006/bbrc.1996.0127

PubMed ID: 15769751

Title: Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate.

PubMed ID: 15769751

DOI: 10.1074/jbc.m413183200

PubMed ID: 18175805

Title: Murine and human autotaxin alpha, beta, and gamma isoforms: gene organization, tissue distribution, and biochemical characterization.

PubMed ID: 18175805

DOI: 10.1074/jbc.m708705200

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12176993

Title: Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase.

PubMed ID: 12176993

DOI: 10.1074/jbc.m205623200

PubMed ID: 1733949

Title: Identification, purification, and partial sequence analysis of autotaxin, a novel motility-stimulating protein.

PubMed ID: 1733949

DOI: 10.1016/s0021-9258(18)45911-x

PubMed ID: 11559573

Title: Autotaxin (NPP-2), a metastasis-enhancing mitogen, is an angiogenic factor.

PubMed ID: 11559573

PubMed ID: 12354767

Title: Serum lysophosphatidic acid is produced through diverse phospholipase pathways.

PubMed ID: 12354767

DOI: 10.1074/jbc.m206812200

PubMed ID: 14500380

Title: Autotaxin hydrolyzes sphingosylphosphorylcholine to produce the regulator of migration, sphingosine-1-phosphate.

PubMed ID: 14500380

PubMed ID: 15700135

Title: Potential involvement of adipocyte insulin resistance in obesity-associated up-regulation of adipocyte lysophospholipase D/autotaxin expression.

PubMed ID: 15700135

DOI: 10.1007/s00125-004-1660-8

PubMed ID: 21393252

Title: The phospholipase A1 activity of lysophospholipase A-I links platelet activation to LPA production during blood coagulation.

PubMed ID: 21393252

DOI: 10.1194/jlr.m013326

PubMed ID: 21240271

Title: Structural basis of substrate discrimination and integrin binding by autotaxin.

PubMed ID: 21240271

DOI: 10.1038/nsmb.1980

PubMed ID: 26371182

Title: Structural Basis for Inhibition of Human Autotaxin by Four Potent Compounds with Distinct Modes of Binding.

PubMed ID: 26371182

DOI: 10.1124/mol.115.100404

PubMed ID: 28414242

Title: Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2-a]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation for the Treatment of Idiopathic Pulmonary Fibrosis.

PubMed ID: 28414242

DOI: 10.1021/acs.jmedchem.7b00032

PubMed ID: 27754931

Title: Selective Inhibition of Autotaxin Is Efficacious in Mouse Models of Liver Fibrosis.

PubMed ID: 27754931

DOI: 10.1124/jpet.116.237156

Sequence Information:

  • Length: 863
  • Mass: 98994
  • Checksum: 94A7A2B3701F0993
  • Sequence:
    • MARRSSFQSC QIISLFTFAV GVNICLGFTA HRIKRAEGWE EGPPTVLSDS PWTNISGSCK 
GRCFELQEAG PPDCRCDNLC KSYTSCCHDF DELCLKTARG WECTKDRCGE VRNEENACHC 
SEDCLARGDC CTNYQVVCKG ESHWVDDDCE EIKAAECPAG FVRPPLIIFS VDGFRASYMK 
KGSKVMPNIE KLRSCGTHSP YMRPVYPTKT FPNLYTLATG LYPESHGIVG NSMYDPVFDA 
TFHLRGREKF NHRWWGGQPL WITATKQGVK AGTFFWSVVI PHERRILTIL QWLTLPDHER 
PSVYAFYSEQ PDFSGHKYGP FGPEMTNPLR EIDKIVGQLM DGLKQLKLHR CVNVIFVGDH 
GMEDVTCDRT EFLSNYLTNV DDITLVPGTL GRIRSKFSNN AKYDPKAIIA NLTCKKPDQH 
FKPYLKQHLP KRLHYANNRR IEDIHLLVER RWHVARKPLD VYKKPSGKCF FQGDHGFDNK 
VNSMQTVFVG YGSTFKYKTK VPPFENIELY NVMCDLLGLK PAPNNGTHGS LNHLLRTNTF 
RPTMPEEVTR PNYPGIMYLQ SDFDLGCTCD DKVEPKNKLD ELNKRLHTKG STEERHLLYG 
RPAVLYRTRY DILYHTDFES GYSEIFLMPL WTSYTVSKQA EVSSVPDHLT SCVRPDVRVS 
PSFSQNCLAY KNDKQMSYGF LFPPYLSSSP EAKYDAFLVT NMVPMYPAFK RVWNYFQRVL 
VKKYASERNG VNVISGPIFD YDYDGLHDTE DKIKQYVEGS SIPVPTHYYS IITSCLDFTQ 
PADKCDGPLS VSSFILPHRP DNEESCNSSE DESKWVEELM KMHTARVRDI EHLTSLDFFR 
KTSRSYPEIL TLKTYLHTYE SEI

Genular Protein ID: 2168891422

Symbol: E7EUF1_HUMAN

Name: N/A

UniProtKB Accession Codes:

E7EUF1

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 3 GeneTree 1 HGNC 1 InterPro 9 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 3 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 3 SMR 1 SUPFAM 3 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

Sequence Information:

  • Length: 884
  • Mass: 101553
  • Checksum: 92F428050302F09A
  • Sequence:
    • MTRHADRIIS LFTFAVGVNI CLGFTAHRIK RAEGWEEGPP TVLSDSPWTN ISGSCKGRCF 
ELQEAGPPDC RCDNLCKSYT SCCHDFDELC LKTARGWECT KDRCGEVRNE ENACHCSEDC 
LARGDCCTNY QVVCKGESHW VDDDCEEIKA AECPAGFVRP PLIIFSVDGF RASYMKKGSK 
VMPNIEKLRS CGTHSPYMRP VYPTKTFPNL YTLATGLYPE SHGIVGNSMY DPVFDATFHL 
RGREKFNHRW WGGQPLWITA TKQGVKAGTF FWSVVIPHER RILTILQWLT LPDHERPSVY 
AFYSEQPDFS GHKYGPFGPE MTNPLREIDK IVGQLMDGLK QLKLHRCVNV IFVGDHGMED 
VTCDRTEFLS NYLTNVDDIT LVPGTLGRIR SKFSNNAKYD PKAIIANLTC KKPDQHFKPY 
LKQHLPKRLH YANNRRIEDI HLLVERRWHV ARKPLDVYKK PSGKCFFQGD HGFDNKVNSM 
QTVFVGYGST FKYKTKVPPF ENIELYNVMC DLLGLKPAPN NGTHGSLNHL LRTNTFRPTM 
PEEVTRPNYP GIMYLQSDFD LGCTCDDKVE PKNKLDELNK RLHTKGSTEA ETRKFRGSRN 
ENKENINGNF EPRKERHLLY GRPAVLYRTR YDILYHTDFE SGYSEIFLMP LWTSYTVSKQ 
AEVSSVPDHL TSCVRPDVRV SPSFSQNCLA YKNDKQMSYG FLFPPYLSSS PEAKYDAFLV 
TNMVPMYPAF KRVWNYFQRV LVKKYASERN GVNVISGPIF DYDYDGLHDT EDKIKQYVEG 
SSIPVPTHYY SIITSCLDFT QPADKCDGPL SVSSFILPHR PDNEESCNSS EDESKWVEEL 
MKMHTARVRD IEHLTSLDFF RKTSRSYPEI LTLKTYLHTY ESEI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.