Details for: ADA2

Gene ID: 51816

Symbol: ADA2

Ensembl ID: ENSG00000093072

Description: adenosine deaminase 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 40.4178
    Cell Significance Index: -16.4200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 35.1488
    Cell Significance Index: -18.0800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 34.5461
    Cell Significance Index: -16.3100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 17.2402
    Cell Significance Index: -16.4600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 5.7226
    Cell Significance Index: -15.3300
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 5.0177
    Cell Significance Index: 92.7400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 3.6042
    Cell Significance Index: -11.0700
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 3.3478
    Cell Significance Index: 22.2100
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 3.2606
    Cell Significance Index: 53.7300
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 3.2447
    Cell Significance Index: 50.2000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.1250
    Cell Significance Index: 23.9600
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: 1.0707
    Cell Significance Index: 6.8400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9195
    Cell Significance Index: 830.2100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.6614
    Cell Significance Index: 71.9400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6278
    Cell Significance Index: 37.6900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5817
    Cell Significance Index: 94.6200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5078
    Cell Significance Index: 50.2300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.4891
    Cell Significance Index: 93.0800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.3507
    Cell Significance Index: 9.3800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3465
    Cell Significance Index: 189.2200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3360
    Cell Significance Index: 23.2400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3232
    Cell Significance Index: 58.2600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2446
    Cell Significance Index: 30.0800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.2042
    Cell Significance Index: 3.5000
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 0.1852
    Cell Significance Index: 1.0100
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.1391
    Cell Significance Index: 4.4000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1231
    Cell Significance Index: 7.9500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.1010
    Cell Significance Index: 0.9300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0483
    Cell Significance Index: 17.3200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0467
    Cell Significance Index: 9.3700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0461
    Cell Significance Index: 5.3700
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0346
    Cell Significance Index: 47.0100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0334
    Cell Significance Index: 4.5800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0333
    Cell Significance Index: 61.4700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0231
    Cell Significance Index: 35.6300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0216
    Cell Significance Index: 9.5600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0174
    Cell Significance Index: 32.7500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0139
    Cell Significance Index: 2.7500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0050
    Cell Significance Index: 0.1500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0030
    Cell Significance Index: 0.1700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0019
    Cell Significance Index: 1.2000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0001
    Cell Significance Index: -0.0100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0030
    Cell Significance Index: -2.0600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0046
    Cell Significance Index: -0.4700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0070
    Cell Significance Index: -0.4400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0102
    Cell Significance Index: -7.5200
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.0117
    Cell Significance Index: -0.2700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0125
    Cell Significance Index: -9.2000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0156
    Cell Significance Index: -11.7900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0167
    Cell Significance Index: -9.4400
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: -0.0191
    Cell Significance Index: -0.1500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0240
    Cell Significance Index: -0.5200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0262
    Cell Significance Index: -1.3600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0290
    Cell Significance Index: -13.1500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0298
    Cell Significance Index: -3.5100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0307
    Cell Significance Index: -8.8400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0336
    Cell Significance Index: -1.1800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0342
    Cell Significance Index: -4.9700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0356
    Cell Significance Index: -0.7800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0364
    Cell Significance Index: -1.6500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0447
    Cell Significance Index: -1.1800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0495
    Cell Significance Index: -6.3400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0622
    Cell Significance Index: -1.5900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0758
    Cell Significance Index: -15.9600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0785
    Cell Significance Index: -8.9900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0790
    Cell Significance Index: -2.5300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0853
    Cell Significance Index: -11.0200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0894
    Cell Significance Index: -15.2600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1005
    Cell Significance Index: -7.1100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1347
    Cell Significance Index: -14.0300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1393
    Cell Significance Index: -1.6600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1430
    Cell Significance Index: -7.2300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1553
    Cell Significance Index: -4.3400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1558
    Cell Significance Index: -11.6100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1572
    Cell Significance Index: -9.6600
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1864
    Cell Significance Index: -1.9300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1888
    Cell Significance Index: -14.9600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1942
    Cell Significance Index: -13.0600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.1989
    Cell Significance Index: -5.8400
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1991
    Cell Significance Index: -4.1300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2005
    Cell Significance Index: -9.4300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2098
    Cell Significance Index: -12.8600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2175
    Cell Significance Index: -3.6400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2273
    Cell Significance Index: -10.6000
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.2336
    Cell Significance Index: -3.5200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2583
    Cell Significance Index: -6.6400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2593
    Cell Significance Index: -11.4700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2630
    Cell Significance Index: -13.8100
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.2665
    Cell Significance Index: -5.2100
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.2730
    Cell Significance Index: -11.8700
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.2801
    Cell Significance Index: -11.4800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2819
    Cell Significance Index: -9.8000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3082
    Cell Significance Index: -11.6700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3097
    Cell Significance Index: -16.1300
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.3363
    Cell Significance Index: -4.1600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.3391
    Cell Significance Index: -9.2300
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.3435
    Cell Significance Index: -8.3200
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3694
    Cell Significance Index: -12.9400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.3746
    Cell Significance Index: -7.8400
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.3847
    Cell Significance Index: -5.6800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ADA2 is a cytoplasmic protein that belongs to the ADAR (adenosine deaminase acting on RNA) family of enzymes. It is highly expressed in various cell types, including mucosal type mast cells, peripheral blood mononuclear cells, smooth muscle fibers of the ileum, ciliated cells of the bronchus, and epithelial cells of the pancreas and fallopian tube. ADA2 is characterized by its ability to bind to heparin, participate in protein homodimerization, and regulate signal transduction pathways. **Pathways and Functions:** ADA2 is involved in multiple signaling pathways that modulate immune responses and cellular homeostasis. These pathways include: 1. **Immune System:** ADA2 regulates the activity of immune cells, such as CD8-alpha-beta-positive, alpha-beta intraepithelial T cells, and classical monocytes, by modulating their signaling pathways. 2. **Innate Immunity:** ADA2 participates in the regulation of innate immune responses, including neutrophil degranulation and surfactant metabolism. 3. **Cell Signaling:** ADA2 modulates signal transduction pathways, including those involved in growth factor activity, protein metabolism, and inosine biosynthesis. 4. **Cellular Homeostasis:** ADA2 regulates cellular processes, such as protein homodimerization, proteoglycan binding, and zinc ion binding, which are essential for maintaining cellular balance. **Clinical Significance:** Dysregulation of ADA2 has been implicated in various diseases, including: 1. **Immunodeficiency Disorders:** Mutations in the ADA2 gene have been associated with immunodeficiency disorders, such as severe combined immunodeficiency (SCID). 2. **Cancer:** ADA2 expression has been found to be altered in various types of cancer, including leukemia and lymphoma. 3. **Autoimmune Diseases:** ADA2 has been implicated in the pathogenesis of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. In conclusion, ADA2 is a multifunctional gene that plays a critical role in regulating immune responses, cellular homeostasis, and protein metabolism. Its dysregulation has been implicated in various diseases, highlighting the importance of ADA2 in maintaining immune balance and cellular balance. Further research is needed to elucidate the mechanisms by which ADA2 regulates cellular processes and to explore its therapeutic potential in the treatment of diseases associated with ADA2 dysfunction.

Genular Protein ID: 3972606139

Symbol: ADA2_HUMAN

Name: Cat eye syndrome critical region protein 1

UniProtKB Accession Codes:

Q9NZK5 A8K9H4 Q6ICF1 Q86UB6 Q8NCJ2 Q96K41

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 10 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 8 Ensembl 10 EvolutionaryTrace 1 ExpressionAtlas 1 GO 13 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 5 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 2 RefSeq 7 Rhea 1 SMR 1 STRING 1 SUPFAM 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10756095

Title: The human homolog of insect-derived growth factor, CECR1, is a candidate gene for features of cat eye syndrome.

PubMed ID: 10756095

DOI: 10.1006/geno.1999.6099

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15926889

Title: Human ADA2 belongs to a new family of growth factors with adenosine deaminase activity.

PubMed ID: 15926889

DOI: 10.1042/bj20050683

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 20453107

Title: Human adenosine deaminase 2 induces differentiation of monocytes into macrophages and stimulates proliferation of T helper cells and macrophages.

PubMed ID: 20453107

DOI: 10.1189/jlb.1109764

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 20147294

Title: Structural basis for the growth factor activity of human adenosine deaminase ADA2.

PubMed ID: 20147294

DOI: 10.1074/jbc.m109.083527

PubMed ID: 24552284

Title: Early-onset stroke and vasculopathy associated with mutations in ADA2.

PubMed ID: 24552284

DOI: 10.1056/nejmoa1307361

PubMed ID: 24552285

Title: Mutant adenosine deaminase 2 in a polyarteritis nodosa vasculopathy.

PubMed ID: 24552285

DOI: 10.1056/nejmoa1307362

PubMed ID: 25075847

Title: Mutant ADA2 in vasculopathies.

PubMed ID: 25075847

DOI: 10.1056/nejmc1405506

Sequence Information:

  • Length: 511
  • Mass: 58934
  • Checksum: A4AB0A83E8A0611E
  • Sequence:
    • MLVDGPSERP ALCFLLLAVA MSFFGSALSI DETRAHLLLK EKMMRLGGRL VLNTKEELAN 
ERLMTLKIAE MKEAMRTLIF PPSMHFFQAK HLIERSQVFN ILRMMPKGAA LHLHDIGIVT 
MDWLVRNVTY RPHCHICFTP RGIMQFRFAH PTPRPSEKCS KWILLEDYRK RVQNVTEFDD 
SLLRNFTLVT QHPEVIYTNQ NVVWSKFETI FFTISGLIHY APVFRDYVFR SMQEFYEDNV 
LYMEIRARLL PVYELSGEHH DEEWSVKTYQ EVAQKFVETH PEFIGIKIIY SDHRSKDVAV 
IAESIRMAMG LRIKFPTVVA GFDLVGHEDT GHSLHDYKEA LMIPAKDGVK LPYFFHAGET 
DWQGTSIDRN ILDALMLNTT RIGHGFALSK HPAVRTYSWK KDIPIEVCPI SNQVLKLVSD 
LRNHPVATLM ATGHPMVISS DDPAMFGAKG LSYDFYEVFM GIGGMKADLR TLKQLAMNSI 
KYSTLLESEK NTFMEIWKKR WDKFIADVAT K

Genular Protein ID: 858678669

Symbol: B4E3Q4_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4E3Q4

Database IDs:

ARBA 8 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 6 DNASU 1 DisGeNET 1 EC 1 EMBL 6 Ensembl 3 GO 5 Gene3D 1 GeneTree 1 HGNC 1 InterPro 5 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 4 Proteomes 2 ProteomicsDB 2 RefSeq 3 Rhea 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 18477386

Title: Finishing the finished human chromosome 22 sequence.

PubMed ID: 18477386

DOI: 10.1186/gb-2008-9-5-r78

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 469
  • Mass: 54360
  • Checksum: 5BF79F3CD63A449C
  • Sequence:
    • MMRLGGRLVL NTKEELANER LMTLKIAEMK EAMRTLIFPP SMHFFQAKHL IERSQVFNIL 
RMMPKGAALH LHDIGIVTMD WLVRNVTYRP HCHICFTPRG IMQFRFAHPT PRPSEKCSKW 
ILLEDYRKRV QNVTEFDDSL LRNFTLVTQH PEVIYTNQNV VWSKFETIFF TISGLIHYAP 
VFRDYVFRSM QEFYEDNVLY MEIRARLLPV YELSGEHHDE EWSVKTYQEV AQKFVETHPE 
FIGIKIIYSD HRSKDVAVIA ESIRMAMGLR IKFPTVVAGF DLVGHEDTGH SLHDYKEALM 
IPAKDGVKLP YFFHAGETDW QGTSIDRNIL DALMLNTTRI GHGFALSKHP AVRTYSWKKD 
IPIEVCPISN QVLKLVSDLR NHPVATLMAT GHPMVISSDD PAMFGAKGLS YDFYEVFMGI 
GGMKADLRTL KQLAMNSIKY STLLESEKNT FMEIWKKRWD KFIADVATK

Genular Protein ID: 1895259400

Symbol: A0A087X0I3_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087X0I3

Database IDs:

ARBA 6 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 6 DNASU 1 DisGeNET 1 EC 1 EMBL 4 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 18477386

Title: Finishing the finished human chromosome 22 sequence.

PubMed ID: 18477386

DOI: 10.1186/gb-2008-9-5-r78

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 391
  • Mass: 45361
  • Checksum: C373B37A3C4EAEDB
  • Sequence:
    • MDWLVRNVTY RPHCHICFTP RGIMQFRFAH PTPRPSEKCS KWILLEDYRK RVQNVTEFDD 
SLLRNFTLVT QHPEVIYTNQ NVVWSKFETI FFTISGLIHY APVFRDYVFR SMQEFYEDNV 
LYMEIRARLL PVYELSGEHH DEEWSVKTYQ EVAQKFVETH PEFIGIKIIY SDHRSKDVAV 
IAESIRMAMG LRIKFPTVVA GFDLVGHEDT GHSLHDYKEA LMIPAKDGVK LPYFFHAGET 
DWQGTSIDRN ILDALMLNTT RIGHGFALSK HPAVRTYSWK KDIPIEVCPI SNQVLKLVSD 
LRNHPVATLM ATGHPMVISS DDPAMFGAKG LSYDFYEVFM GIGGMKADLR TLKQLAMNSI 
KYSTLLESEK NTFMEIWKKR WDKFIADVAT K

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.